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The map label for this gene is aofH [H]

Identifier: 119867626

GI number: 119867626

Start: 1694893

End: 1696245

Strand: Reverse

Name: aofH [H]

Synonym: Mkms_1580

Alternate gene names: 119867626

Gene position: 1696245-1694893 (Counterclockwise)

Preceding gene: 119867629

Following gene: 119867624

Centisome position: 29.57

GC content: 72.14

Gene sequence:

>1353_bases
ATGACAGCACCGGCCGGCGCCGACGTCGTCGTGGTGGGGGCCGGGTTCGCCGGGCTCACGGCGGCCCGCGAACTCACCCG
CCGCGGCCACGACGTGGTGGTGTTCGAGGGACGGGACCGGGTCGGCGGACGGGCGTACACCACCACCGTCGCCGGCGTCC
CGGTCGACCTGGGTGCCTCGTTCATCGGGCCGACCCAGGACGCGGTCATCGCGCTGGCGGCCGAACTGGGCTGCGACACC
GTCCGCACCTACAACCGCGGCAACAACCTGATCCGCTGGCGCGGGCGGGTGCGCTCCTACCGCAGCACCATCCCGCGTCT
GTCGATCATCGAACTGCTCGACGTGAGCCGCATCCAGTGGCGGTTCGAGCGGTTGTGCAAACAGATCCCGCTCGCCGCGC
CGTGGACCGCGCCCGCGGCCCACCGACTCGACGACCTCAGCCTCGAATCGTGGCTGCGGTCGGTGCACGCCAGCGCGTCG
ACGCGCGACCTGATGGCGATCATGTCCCGGGTCACGTGGGGGTGCGAACCCGACGCGGTGTCGCTGCTGCACGCCGCGCG
CTACGTCAAGGCGGCGGGCGGTATCGGGTGCATGCTCGACGTCGAGGGCGGAGCGCAACAGGACCGTTTCCCGGGCGGCT
CCCAGCAGATCGCGGTGCGGATGGCAGCCGAACTGGGCGACCGGGTGGTCACCGGTGCGCCGGTACGCCGCATCGGGCGG
GACACCGACGGGGCGCTGCACGTCCACACCGAGCGCGGCAGCACGGCGGCGCGGGCGGTGATCGTCGCCGTGGCACCCGC
CCACCGCGAGACCATCGAGTTCGAACCGCGACTGCCCGCCGGTTACGCCGATCTGGCCGCGCACTGGCCGCAGGGCCGGC
TGAGCAAGGCCTACGCCGCCTACGACACACCGTTCTGGCGCGACGGCGGATGCTCGGGTGAGGCGTTGTCCGACGAGGGT
CCGGTGTTCATCACCTTCGACGTCAGTCCGTCGGACAAGGGCCCGGGCATCCTGCTGGGGTTCACGAACGCGGCGTCGTT
CGACCTGCTCTCCCCCGACGAGCGCCGCAGCCGCGCACTGGCCGGATTCGCCGCGCTGTTCGGCGACGCCGCATCGTCAC
CGATCGACTACGTCGATCACCTGTGGGGCGCCGACGAGTTCGCACCGGGCGGCCCGACCGCGGCGGTGCCGCCCGGCGCA
TGGCTGGCCTACGGTCAGTGGCTGCGCACACCGGTCCACGGAATCCATTGGGCGGGAACGGAAACCGCGGACGAATGGAC
GGGCTTCCTCGACGGCGCGGTGCGCTCGGGGCAGCGGGCCGCAACCGAGGTGCACGACCTCTTGTCGCGTTAG

Upstream 100 bases:

>100_bases
GCCGTCGGCGCCCGCTTCGCGCAGCGCGTGTGCCCGTCGGATCGCATCTGTCGGGCCGAACAGCGCCGTCATCACCTGCA
CGACGTGAGAGCCTAGTCGG

Downstream 100 bases:

>100_bases
GACCCCGCCGTCACGACGTGGCGCGGCGCGGGGTGGCCACCGACTCGACCAGATTGCGCAGCGCACCGTTGACCTCGTGA
GGCCGTTCCAGGATGGCGCA

Product: amine oxidase

Products: RCHO; NH3; H2O2

Alternate protein names: NA

Number of amino acids: Translated: 450; Mature: 449

Protein sequence:

>450_residues
MTAPAGADVVVVGAGFAGLTAARELTRRGHDVVVFEGRDRVGGRAYTTTVAGVPVDLGASFIGPTQDAVIALAAELGCDT
VRTYNRGNNLIRWRGRVRSYRSTIPRLSIIELLDVSRIQWRFERLCKQIPLAAPWTAPAAHRLDDLSLESWLRSVHASAS
TRDLMAIMSRVTWGCEPDAVSLLHAARYVKAAGGIGCMLDVEGGAQQDRFPGGSQQIAVRMAAELGDRVVTGAPVRRIGR
DTDGALHVHTERGSTAARAVIVAVAPAHRETIEFEPRLPAGYADLAAHWPQGRLSKAYAAYDTPFWRDGGCSGEALSDEG
PVFITFDVSPSDKGPGILLGFTNAASFDLLSPDERRSRALAGFAALFGDAASSPIDYVDHLWGADEFAPGGPTAAVPPGA
WLAYGQWLRTPVHGIHWAGTETADEWTGFLDGAVRSGQRAATEVHDLLSR

Sequences:

>Translated_450_residues
MTAPAGADVVVVGAGFAGLTAARELTRRGHDVVVFEGRDRVGGRAYTTTVAGVPVDLGASFIGPTQDAVIALAAELGCDT
VRTYNRGNNLIRWRGRVRSYRSTIPRLSIIELLDVSRIQWRFERLCKQIPLAAPWTAPAAHRLDDLSLESWLRSVHASAS
TRDLMAIMSRVTWGCEPDAVSLLHAARYVKAAGGIGCMLDVEGGAQQDRFPGGSQQIAVRMAAELGDRVVTGAPVRRIGR
DTDGALHVHTERGSTAARAVIVAVAPAHRETIEFEPRLPAGYADLAAHWPQGRLSKAYAAYDTPFWRDGGCSGEALSDEG
PVFITFDVSPSDKGPGILLGFTNAASFDLLSPDERRSRALAGFAALFGDAASSPIDYVDHLWGADEFAPGGPTAAVPPGA
WLAYGQWLRTPVHGIHWAGTETADEWTGFLDGAVRSGQRAATEVHDLLSR
>Mature_449_residues
TAPAGADVVVVGAGFAGLTAARELTRRGHDVVVFEGRDRVGGRAYTTTVAGVPVDLGASFIGPTQDAVIALAAELGCDTV
RTYNRGNNLIRWRGRVRSYRSTIPRLSIIELLDVSRIQWRFERLCKQIPLAAPWTAPAAHRLDDLSLESWLRSVHASAST
RDLMAIMSRVTWGCEPDAVSLLHAARYVKAAGGIGCMLDVEGGAQQDRFPGGSQQIAVRMAAELGDRVVTGAPVRRIGRD
TDGALHVHTERGSTAARAVIVAVAPAHRETIEFEPRLPAGYADLAAHWPQGRLSKAYAAYDTPFWRDGGCSGEALSDEGP
VFITFDVSPSDKGPGILLGFTNAASFDLLSPDERRSRALAGFAALFGDAASSPIDYVDHLWGADEFAPGGPTAAVPPGAW
LAYGQWLRTPVHGIHWAGTETADEWTGFLDGAVRSGQRAATEVHDLLSR

Specific function: Unknown

COG id: COG1231

COG function: function code E; Monoamine oxidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the flavin monoamine oxidase family [H]

Homologues:

Organism=Homo sapiens, GI4557735, Length=452, Percent_Identity=32.9646017699115, Blast_Score=245, Evalue=8e-65,
Organism=Homo sapiens, GI38202207, Length=447, Percent_Identity=34.2281879194631, Blast_Score=229, Evalue=3e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001613
- InterPro:   IPR002937 [H]

Pfam domain/function: PF01593 Amino_oxidase [H]

EC number: 1.4.3.4

Molecular weight: Translated: 48096; Mature: 47964

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAPAGADVVVVGAGFAGLTAARELTRRGHDVVVFEGRDRVGGRAYTTTVAGVPVDLGAS
CCCCCCCCEEEEECCHHHHHHHHHHHHCCCEEEEECCCCCCCCEEEEEEECCCCHHCCCC
FIGPTQDAVIALAAELGCDTVRTYNRGNNLIRWRGRVRSYRSTIPRLSIIELLDVSRIQW
CCCCCHHHHHHHHHHHCCHHHHHHHCCCCEEEEHHHHHHHHHHCCCHHHHHHHHHHHHHH
RFERLCKQIPLAAPWTAPAAHRLDDLSLESWLRSVHASASTRDLMAIMSRVTWGCEPDAV
HHHHHHHHCCCCCCCCCCHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHH
SLLHAARYVKAAGGIGCMLDVEGGAQQDRFPGGSQQIAVRMAAELGDRVVTGAPVRRIGR
HHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCEEECCCCHHHHCC
DTDGALHVHTERGSTAARAVIVAVAPAHRETIEFEPRLPAGYADLAAHWPQGRLSKAYAA
CCCCEEEEEECCCCCHHEEEEEEECCCCCCCEEECCCCCCCHHHHHHHCCCCHHHHHHHH
YDTPFWRDGGCSGEALSDEGPVFITFDVSPSDKGPGILLGFTNAASFDLLSPDERRSRAL
CCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHH
AGFAALFGDAASSPIDYVDHLWGADEFAPGGPTAAVPPGAWLAYGQWLRTPVHGIHWAGT
HHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEECCC
ETADEWTGFLDGAVRSGQRAATEVHDLLSR
CCHHHHHHHHHHHHHCCHHHHHHHHHHHCC
>Mature Secondary Structure 
TAPAGADVVVVGAGFAGLTAARELTRRGHDVVVFEGRDRVGGRAYTTTVAGVPVDLGAS
CCCCCCCEEEEECCHHHHHHHHHHHHCCCEEEEECCCCCCCCEEEEEEECCCCHHCCCC
FIGPTQDAVIALAAELGCDTVRTYNRGNNLIRWRGRVRSYRSTIPRLSIIELLDVSRIQW
CCCCCHHHHHHHHHHHCCHHHHHHHCCCCEEEEHHHHHHHHHHCCCHHHHHHHHHHHHHH
RFERLCKQIPLAAPWTAPAAHRLDDLSLESWLRSVHASASTRDLMAIMSRVTWGCEPDAV
HHHHHHHHCCCCCCCCCCHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHH
SLLHAARYVKAAGGIGCMLDVEGGAQQDRFPGGSQQIAVRMAAELGDRVVTGAPVRRIGR
HHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCEEECCCCHHHHCC
DTDGALHVHTERGSTAARAVIVAVAPAHRETIEFEPRLPAGYADLAAHWPQGRLSKAYAA
CCCCEEEEEECCCCCHHEEEEEEECCCCCCCEEECCCCCCCHHHHHHHCCCCHHHHHHHH
YDTPFWRDGGCSGEALSDEGPVFITFDVSPSDKGPGILLGFTNAASFDLLSPDERRSRAL
CCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCEEEEEECCCCCCCCCCCHHHHHHHH
AGFAALFGDAASSPIDYVDHLWGADEFAPGGPTAAVPPGAWLAYGQWLRTPVHGIHWAGT
HHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEECCC
ETADEWTGFLDGAVRSGQRAATEVHDLLSR
CCHHHHHHHHHHHHHCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: RCH2NH2; H2O; O2

Specific reaction: RCH2NH2 + H2O + O2 = RCHO + NH3 + H2O2

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]