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The map label for this gene is qorA [H]

Identifier: 119867624

GI number: 119867624

Start: 1692627

End: 1693628

Strand: Reverse

Name: qorA [H]

Synonym: Mkms_1577

Alternate gene names: 119867624

Gene position: 1693628-1692627 (Counterclockwise)

Preceding gene: 119867626

Following gene: 119867621

Centisome position: 29.52

GC content: 69.26

Gene sequence:

>1002_bases
ATGGTTCCCGTCGACGGAAGGAAGGCGACCATGCGCGCGGTTCAGATTGACCGATTGGACGGTCCCGGCTCGGTACAGGT
CGTCGACGTCGACGAGCCCGACAGCGCCGATGGGGTGCTGATCGATGTGCACGCGGCCGGGGTGGCGTTCCCCGATGCGC
TGCTCACCCGCGGGCTCTACCAGTACAAGCCGGACCTGCCGTTCACCCCGGGCGCCGAGATCGCCGGTGTGGTGCGCAGC
GCCCCCGCAGGATCGGGGGTGTCGCCGGGTGATCGGGTCGCGGGTCTGACGATGCTGTCCGGTGGCATGGCCGAAGTCAT
TGCGCTGGCCCCGGATCGGGTGTTCCCGCTGCCCGACGCGGTGTCGTTCGAAGCCGGCGCGGGGCTGTTGTTCAACGATC
TGACCGTGCACTGCGCGTTGCGCACGCGGGGCCGGTTGGCCAAGGGCGAGACGGTCCTCGTCCACGGCGCCGCCGGCGGG
ATCGGCACCTCGACACTGCGGTTGGCTCCGGCGTTCGGTGCGGGACGCACCATCGCCGTGGTCAGCACCGAGGAGAAGAT
CCCGGTGGCACAGGCGGCCGGCGCCGACGAGGTGGTGCTGGCCGACGGGTTCAAGGATGCCGTCAAGGAGTTGACGGATG
GGCGCGGTGTCGACGTCGTGGTCGATCCCGTGGGCGGCGACCGGTTCACCGACTCGCTGCGCTCGCTGGCACCCGGCGGC
CGGCTGTTGGTGATCGGTTTCACCGGCGGCGAGATTCCCACCGTGAAGGTGAACCGGCTGCTGCTCAACAACGTCGATGT
CGTCGGAGTCGGTTGGGGCGCTTGGACTTTCGCGCACCCCGGCTATGTGCGGGAACAGTGGGCCGAACTCGAGCCGCTGT
TGGCGTCCGGCGCGGTGTCCGCGCCGCAACCCGATGTGTTCCCGCTGGAGCGGGCGGCGGAAGCCATTGCGGCACTGGAG
AATCGCAGCGCCAAAGGAAAGGTCGTCATCGCGGTGCGATGA

Upstream 100 bases:

>100_bases
CATGAGGTTCGCTGTCGCCCTCGACGACGCAGCGCGGTGAGTGTCAGCGCCGGCTTCGAGCAGCACCGCGACACGGGCGT
CGATCACCCCGGGATGTTAA

Downstream 100 bases:

>100_bases
GCGCTCAGCCTGCGGCGACGTAGTCCATCGGGGGACCGTCGGGTCCGACGGCGGCCTGGTCGGCGACCGCGGTCGCGACC
GGCTGGCCGGACTGCACCGT

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: NADPH:quinone reductase 1; Zeta-crystallin homolog protein [H]

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MVPVDGRKATMRAVQIDRLDGPGSVQVVDVDEPDSADGVLIDVHAAGVAFPDALLTRGLYQYKPDLPFTPGAEIAGVVRS
APAGSGVSPGDRVAGLTMLSGGMAEVIALAPDRVFPLPDAVSFEAGAGLLFNDLTVHCALRTRGRLAKGETVLVHGAAGG
IGTSTLRLAPAFGAGRTIAVVSTEEKIPVAQAAGADEVVLADGFKDAVKELTDGRGVDVVVDPVGGDRFTDSLRSLAPGG
RLLVIGFTGGEIPTVKVNRLLLNNVDVVGVGWGAWTFAHPGYVREQWAELEPLLASGAVSAPQPDVFPLERAAEAIAALE
NRSAKGKVVIAVR

Sequences:

>Translated_333_residues
MVPVDGRKATMRAVQIDRLDGPGSVQVVDVDEPDSADGVLIDVHAAGVAFPDALLTRGLYQYKPDLPFTPGAEIAGVVRS
APAGSGVSPGDRVAGLTMLSGGMAEVIALAPDRVFPLPDAVSFEAGAGLLFNDLTVHCALRTRGRLAKGETVLVHGAAGG
IGTSTLRLAPAFGAGRTIAVVSTEEKIPVAQAAGADEVVLADGFKDAVKELTDGRGVDVVVDPVGGDRFTDSLRSLAPGG
RLLVIGFTGGEIPTVKVNRLLLNNVDVVGVGWGAWTFAHPGYVREQWAELEPLLASGAVSAPQPDVFPLERAAEAIAALE
NRSAKGKVVIAVR
>Mature_333_residues
MVPVDGRKATMRAVQIDRLDGPGSVQVVDVDEPDSADGVLIDVHAAGVAFPDALLTRGLYQYKPDLPFTPGAEIAGVVRS
APAGSGVSPGDRVAGLTMLSGGMAEVIALAPDRVFPLPDAVSFEAGAGLLFNDLTVHCALRTRGRLAKGETVLVHGAAGG
IGTSTLRLAPAFGAGRTIAVVSTEEKIPVAQAAGADEVVLADGFKDAVKELTDGRGVDVVVDPVGGDRFTDSLRSLAPGG
RLLVIGFTGGEIPTVKVNRLLLNNVDVVGVGWGAWTFAHPGYVREQWAELEPLLASGAVSAPQPDVFPLERAAEAIAALE
NRSAKGKVVIAVR

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI194239674, Length=332, Percent_Identity=30.421686746988, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI13236495, Length=332, Percent_Identity=30.421686746988, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI18379349, Length=319, Percent_Identity=29.7805642633229, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI194239676, Length=191, Percent_Identity=36.6492146596859, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI24308257, Length=351, Percent_Identity=26.7806267806268, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI41872631, Length=311, Percent_Identity=28.9389067524116, Blast_Score=89, Evalue=8e-18,
Organism=Homo sapiens, GI22538446, Length=246, Percent_Identity=26.8292682926829, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI22538444, Length=246, Percent_Identity=26.8292682926829, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI67078404, Length=291, Percent_Identity=25.085910652921, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI67078406, Length=285, Percent_Identity=25.2631578947368, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI197927207, Length=191, Percent_Identity=27.2251308900524, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1790485, Length=334, Percent_Identity=32.0359281437126, Blast_Score=115, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI17507255, Length=345, Percent_Identity=29.8550724637681, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17556000, Length=331, Percent_Identity=23.5649546827795, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17536829, Length=328, Percent_Identity=26.8292682926829, Blast_Score=68, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6319520, Length=335, Percent_Identity=29.2537313432836, Blast_Score=98, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 34273; Mature: 34273

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVPVDGRKATMRAVQIDRLDGPGSVQVVDVDEPDSADGVLIDVHAAGVAFPDALLTRGLY
CCCCCCCHHEEEEEEEECCCCCCCEEEEECCCCCCCCCEEEEEEECCCCCCHHHHHCCHH
QYKPDLPFTPGAEIAGVVRSAPAGSGVSPGDRVAGLTMLSGGMAEVIALAPDRVFPLPDA
HCCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHEEEEEECCCHHHEEEECCCCCCCCCCC
VSFEAGAGLLFNDLTVHCALRTRGRLAKGETVLVHGAAGGIGTSTLRLAPAFGAGRTIAV
CCCCCCCCEEEECEEEEEEEECCCCCCCCCEEEEEECCCCCCCCEEEEEECCCCCCEEEE
VSTEEKIPVAQAAGADEVVLADGFKDAVKELTDGRGVDVVVDPVGGDRFTDSLRSLAPGG
EECCCCCCHHHCCCCCCEEEECCHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHCCCC
RLLVIGFTGGEIPTVKVNRLLLNNVDVVGVGWGAWTFAHPGYVREQWAELEPLLASGAVS
EEEEEEECCCCCCEEEEEEEEECCCCEEEECCCHHCCCCCCHHHHHHHHHHHHHHCCCCC
APQPDVFPLERAAEAIAALENRSAKGKVVIAVR
CCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEC
>Mature Secondary Structure
MVPVDGRKATMRAVQIDRLDGPGSVQVVDVDEPDSADGVLIDVHAAGVAFPDALLTRGLY
CCCCCCCHHEEEEEEEECCCCCCCEEEEECCCCCCCCCEEEEEEECCCCCCHHHHHCCHH
QYKPDLPFTPGAEIAGVVRSAPAGSGVSPGDRVAGLTMLSGGMAEVIALAPDRVFPLPDA
HCCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHEEEEEECCCHHHEEEECCCCCCCCCCC
VSFEAGAGLLFNDLTVHCALRTRGRLAKGETVLVHGAAGGIGTSTLRLAPAFGAGRTIAV
CCCCCCCCEEEECEEEEEEEECCCCCCCCCEEEEEECCCCCCCCEEEEEECCCCCCEEEE
VSTEEKIPVAQAAGADEVVLADGFKDAVKELTDGRGVDVVVDPVGGDRFTDSLRSLAPGG
EECCCCCCHHHCCCCCCEEEECCHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHCCCC
RLLVIGFTGGEIPTVKVNRLLLNNVDVVGVGWGAWTFAHPGYVREQWAELEPLLASGAVS
EEEEEEECCCCCCEEEEEEEEECCCCEEEECCCHHCCCCCCHHHHHHHHHHHHHHCCCCC
APQPDVFPLERAAEAIAALENRSAKGKVVIAVR
CCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503; 7602590 [H]