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The map label for this gene is mlhB [H]

Identifier: 119867584

GI number: 119867584

Start: 1649504

End: 1650400

Strand: Direct

Name: mlhB [H]

Synonym: Mkms_1536

Alternate gene names: 119867584

Gene position: 1649504-1650400 (Clockwise)

Preceding gene: 119867581

Following gene: 119867586

Centisome position: 28.75

GC content: 66.56

Gene sequence:

>897_bases
ATGGCGAGGACTGAGGCGCTGGCACGCGTCGAGAAGATGTATGTGGAGGGCTTTCCGGACCCGGCGACGGCCTCTGTGGA
GGACTTGCGAACGGCATACGACGAGCTGTTGCTGCAGTTCGAACTGCCCGCGGGGGTCGAGCCCGTCTCCGGTGAGATCG
GTGGTGTGCCGGTTCTGACCGTGACGGCCGAGGGCGCAACCCGCGACAAAGTGCTCGTGTGGTGCCACGGTGGCGGATAC
GTCCTCGGCAGCGCCAGGGGGTTTCAAGATCTCGGTCACACGTTGTCGCGTGCGTCCGGTGTCACCGTGGTGCTGCCGGA
TTATCGGCGCGCACCGGAGAACAAGTTCCCGGCCGCGGTCGACGATGGTGCCGCGGTGATCTCAGACCTGGTGTCGACCC
TCGGTGCGACGAACGTCGCGGTGGGAGGCGACTCCGCCGGTGGGGGGCTGACACTCGCCGCGCTGACGGCACTGCGCGAT
GGGGGCACACCTCTGCCCGCGGCGGCAGTGTTCATCTCACCGCTGCTGGACTTCACGGCGAGCGGTGCCAGCGTGGATCT
CTACGACGGTAGGGACGTCGCTGTCTCCCGAGGATCGATCGCGAACCTCAGGGAGGCCTACCTGCAGGGCCATGATCCGC
AGGATCCGCTGGCCTCGCCGGTGTTCGCCGATCTCGGAGCGCTACCGCCGTCGTTGTTCCTCGTCGGCTCCGGCGAGGTG
CTTCTCGACGACTCCTGTCGCGCCGCGATGGCGATCACGGAACAGGGCGGCACCGCAACGGTTTCGGTCTACGACGACAT
GGTGCACGTATGGCCGCTCTTCTCGTCGATTCTGCCGGAGGGCGTCGATGCCGCCAACGAAGCCGGAGCGTTCATCCGCA
AGAATCTCGGACTGTGA

Upstream 100 bases:

>100_bases
ACATTTGTGAACAGCGATTATGATAGTAGGAATCGTAGAAGGTCGAAAGAGCCAGGCAAAATGCTCGAAAGTTAGCGCCA
ACTATGCAATGATCGCGACC

Downstream 100 bases:

>100_bases
GCCGTTCCGCTGCACCCGGGTGGTTGAACATCACACCCGGGTGCAGCGGCCGACCGCTGACCTGATCTCTCCTGTCAGGG
CGCCGGAGTCGGGCGGAGGC

Product: alpha/beta hydrolase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 297

Protein sequence:

>298_residues
MARTEALARVEKMYVEGFPDPATASVEDLRTAYDELLLQFELPAGVEPVSGEIGGVPVLTVTAEGATRDKVLVWCHGGGY
VLGSARGFQDLGHTLSRASGVTVVLPDYRRAPENKFPAAVDDGAAVISDLVSTLGATNVAVGGDSAGGGLTLAALTALRD
GGTPLPAAAVFISPLLDFTASGASVDLYDGRDVAVSRGSIANLREAYLQGHDPQDPLASPVFADLGALPPSLFLVGSGEV
LLDDSCRAAMAITEQGGTATVSVYDDMVHVWPLFSSILPEGVDAANEAGAFIRKNLGL

Sequences:

>Translated_298_residues
MARTEALARVEKMYVEGFPDPATASVEDLRTAYDELLLQFELPAGVEPVSGEIGGVPVLTVTAEGATRDKVLVWCHGGGY
VLGSARGFQDLGHTLSRASGVTVVLPDYRRAPENKFPAAVDDGAAVISDLVSTLGATNVAVGGDSAGGGLTLAALTALRD
GGTPLPAAAVFISPLLDFTASGASVDLYDGRDVAVSRGSIANLREAYLQGHDPQDPLASPVFADLGALPPSLFLVGSGEV
LLDDSCRAAMAITEQGGTATVSVYDDMVHVWPLFSSILPEGVDAANEAGAFIRKNLGL
>Mature_297_residues
ARTEALARVEKMYVEGFPDPATASVEDLRTAYDELLLQFELPAGVEPVSGEIGGVPVLTVTAEGATRDKVLVWCHGGGYV
LGSARGFQDLGHTLSRASGVTVVLPDYRRAPENKFPAAVDDGAAVISDLVSTLGATNVAVGGDSAGGGLTLAALTALRDG
GTPLPAAAVFISPLLDFTASGASVDLYDGRDVAVSRGSIANLREAYLQGHDPQDPLASPVFADLGALPPSLFLVGSGEVL
LDDSCRAAMAITEQGGTATVSVYDDMVHVWPLFSSILPEGVDAANEAGAFIRKNLGL

Specific function: Lactone hydrolase that is required for the degradation of monocyclic monoterpenes such as menthol and carvone. Catalyzes the ring opening of lactones formed during degradation of monocyclic monoterpenes. Can hydrolyze epsilon-caprolactone, the lactone der

COG id: COG0657

COG function: function code I; Esterase/lipase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'GDXG' lipolytic enzyme family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17567059, Length=279, Percent_Identity=24.7311827956989, Blast_Score=82, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013094 [H]

Pfam domain/function: PF07859 Abhydrolase_3 [H]

EC number: =3.1.1.83 [H]

Molecular weight: Translated: 30667; Mature: 30536

Theoretical pI: Translated: 4.13; Mature: 4.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARTEALARVEKMYVEGFPDPATASVEDLRTAYDELLLQFELPAGVEPVSGEIGGVPVLT
CCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHEEEECCCCCCCCCCCCCCEEEEE
VTAEGATRDKVLVWCHGGGYVLGSARGFQDLGHTLSRASGVTVVLPDYRRAPENKFPAAV
EEECCCCCCEEEEEECCCCEEEECCCCHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCC
DDGAAVISDLVSTLGATNVAVGGDSAGGGLTLAALTALRDGGTPLPAAAVFISPLLDFTA
CCHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCC
SGASVDLYDGRDVAVSRGSIANLREAYLQGHDPQDPLASPVFADLGALPPSLFLVGSGEV
CCCEEEEECCCEEEECCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCEEEEEECCCE
LLDDSCRAAMAITEQGGTATVSVYDDMVHVWPLFSSILPEGVDAANEAGAFIRKNLGL
EECCCCCEEEEEECCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure 
ARTEALARVEKMYVEGFPDPATASVEDLRTAYDELLLQFELPAGVEPVSGEIGGVPVLT
CHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHEEEECCCCCCCCCCCCCCEEEEE
VTAEGATRDKVLVWCHGGGYVLGSARGFQDLGHTLSRASGVTVVLPDYRRAPENKFPAAV
EEECCCCCCEEEEEECCCCEEEECCCCHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCC
DDGAAVISDLVSTLGATNVAVGGDSAGGGLTLAALTALRDGGTPLPAAAVFISPLLDFTA
CCHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCC
SGASVDLYDGRDVAVSRGSIANLREAYLQGHDPQDPLASPVFADLGALPPSLFLVGSGEV
CCCEEEEECCCEEEECCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCEEEEEECCCE
LLDDSCRAAMAITEQGGTATVSVYDDMVHVWPLFSSILPEGVDAANEAGAFIRKNLGL
EECCCCCEEEEEECCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA