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The map label for this gene is nisX1 [H]

Identifier: 119867581

GI number: 119867581

Start: 1645373

End: 1646188

Strand: Direct

Name: nisX1 [H]

Synonym: Mkms_1533

Alternate gene names: 119867581

Gene position: 1645373-1646188 (Clockwise)

Preceding gene: 119867580

Following gene: 119867584

Centisome position: 28.68

GC content: 64.71

Gene sequence:

>816_bases
GTGACCTGCCGGATCCTGAAGATATCGACCTCAGGCTTTTACGAGTGGCGATCCCGGCCGGCCTCGACGCGCGACCGCGC
GGATGCCGAGTTGGCCAACACGATCGCCGCGATCCATACCGATTCGCGCCAGACCTACGGGGTGCGCCGAATCCGTGCCG
AACTACGCTACGGCTACGGCCTGGCAATCAGCCACAAGCGGGTGTGGCGATGCATGACATTGGTGGGTGTGCAGGGCGTG
CACCGCAGACGGTGGCGCCGGCATAAGCCCTCGCCGGCATCGTGGCCGGACCTGGTGAACCGCCAGTTCCGGGCCGAGGC
GCCCGATCGGTTGTGGGTCACCGACATCACCCAGCACCGCAGCGCCGAGGGCTGGGTCTACGCCGCGGTCGTCCTCGATG
TCTACTCTCGCCGGGTGGTGGGCTGGTCGATCGCAGATCACCTGCGCACCGAACTGGTCGCCGACGCCCTCGACATGGCC
CGGCTGCGCCGCAAACCCGTCGGCACGGTGGTCCATTCGGATCGCGGAACCCAATACACCAGTTGGCTTTTCGGCCACCG
TCTGAGAGAGGCCGGATTGCTGGGCTCGATGGGTAAAGTGGCCTCAGCATTCGACAACGCCATGATCGAATCGTTCTTCG
GATCGATGCAGATCGAGCTCCTTGACCGCCGAACCTGGACTGCTCGCGCCGAACTCGCAACAGCGATCTTCGAGTACATC
GAAGCGTTCTACAACCCCGTGCGCCGCCACAGCGCCCTGGACTACCGCAGCCCCATCGACTACGAAAGACTTCACACCAC
CAACACGGCGGCGTGA

Upstream 100 bases:

>100_bases
TCCTCAAGCGGGCCAGCGCCTACTTCGCCCGGGAAAACATCCTCCCAAAATAGGGTTCCGGCTGGTCTGTGAGCTGGCTG
CGCAGGGTTTCCCTGTCGCG

Downstream 100 bases:

>100_bases
ACACCCAACAGAAACCGTCCGGACAACCGGGAACAGGTCACGAGTGCACTGTGACGGCGTTGAGTGTTGTAGTGCTTGAG
CCAGGGCGCAAGCGCGGCGG

Product: integrase catalytic subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 271; Mature: 270

Protein sequence:

>271_residues
MTCRILKISTSGFYEWRSRPASTRDRADAELANTIAAIHTDSRQTYGVRRIRAELRYGYGLAISHKRVWRCMTLVGVQGV
HRRRWRRHKPSPASWPDLVNRQFRAEAPDRLWVTDITQHRSAEGWVYAAVVLDVYSRRVVGWSIADHLRTELVADALDMA
RLRRKPVGTVVHSDRGTQYTSWLFGHRLREAGLLGSMGKVASAFDNAMIESFFGSMQIELLDRRTWTARAELATAIFEYI
EAFYNPVRRHSALDYRSPIDYERLHTTNTAA

Sequences:

>Translated_271_residues
MTCRILKISTSGFYEWRSRPASTRDRADAELANTIAAIHTDSRQTYGVRRIRAELRYGYGLAISHKRVWRCMTLVGVQGV
HRRRWRRHKPSPASWPDLVNRQFRAEAPDRLWVTDITQHRSAEGWVYAAVVLDVYSRRVVGWSIADHLRTELVADALDMA
RLRRKPVGTVVHSDRGTQYTSWLFGHRLREAGLLGSMGKVASAFDNAMIESFFGSMQIELLDRRTWTARAELATAIFEYI
EAFYNPVRRHSALDYRSPIDYERLHTTNTAA
>Mature_270_residues
TCRILKISTSGFYEWRSRPASTRDRADAELANTIAAIHTDSRQTYGVRRIRAELRYGYGLAISHKRVWRCMTLVGVQGVH
RRRWRRHKPSPASWPDLVNRQFRAEAPDRLWVTDITQHRSAEGWVYAAVVLDVYSRRVVGWSIADHLRTELVADALDMAR
LRRKPVGTVVHSDRGTQYTSWLFGHRLREAGLLGSMGKVASAFDNAMIESFFGSMQIELLDRRTWTARAELATAIFEYIE
AFYNPVRRHSALDYRSPIDYERLHTTNTAA

Specific function: Involved in the transposition of the insertion sequence [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=239, Percent_Identity=36.4016736401674, Blast_Score=137, Evalue=2e-32,
Organism=Escherichia coli, GI1788405, Length=271, Percent_Identity=36.1623616236162, Blast_Score=162, Evalue=3e-41,
Organism=Escherichia coli, GI1787263, Length=271, Percent_Identity=36.1623616236162, Blast_Score=162, Evalue=3e-41,
Organism=Escherichia coli, GI1786753, Length=271, Percent_Identity=36.1623616236162, Blast_Score=162, Evalue=3e-41,
Organism=Escherichia coli, GI1786570, Length=271, Percent_Identity=36.1623616236162, Blast_Score=162, Evalue=3e-41,
Organism=Escherichia coli, GI1786490, Length=271, Percent_Identity=36.1623616236162, Blast_Score=162, Evalue=3e-41,
Organism=Escherichia coli, GI1789981, Length=261, Percent_Identity=30.2681992337165, Blast_Score=120, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 31267; Mature: 31136

Theoretical pI: Translated: 10.63; Mature: 10.63

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTCRILKISTSGFYEWRSRPASTRDRADAELANTIAAIHTDSRQTYGVRRIRAELRYGYG
CCEEEEEEECCCHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC
LAISHKRVWRCMTLVGVQGVHRRRWRRHKPSPASWPDLVNRQFRAEAPDRLWVTDITQHR
EEECHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCEEEEHHHHCC
SAEGWVYAAVVLDVYSRRVVGWSIADHLRTELVADALDMARLRRKPVGTVVHSDRGTQYT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHH
SWLFGHRLREAGLLGSMGKVASAFDNAMIESFFGSMQIELLDRRTWTARAELATAIFEYI
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEEHHCCHHHHHHHHHHHHHHHH
EAFYNPVRRHSALDYRSPIDYERLHTTNTAA
HHHHHHHHHHCCCCCCCCCCHHHHCCCCCCC
>Mature Secondary Structure 
TCRILKISTSGFYEWRSRPASTRDRADAELANTIAAIHTDSRQTYGVRRIRAELRYGYG
CEEEEEEECCCHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCC
LAISHKRVWRCMTLVGVQGVHRRRWRRHKPSPASWPDLVNRQFRAEAPDRLWVTDITQHR
EEECHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCEEEEHHHHCC
SAEGWVYAAVVLDVYSRRVVGWSIADHLRTELVADALDMARLRRKPVGTVVHSDRGTQYT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHH
SWLFGHRLREAGLLGSMGKVASAFDNAMIESFFGSMQIELLDRRTWTARAELATAIFEYI
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEEHHCCHHHHHHHHHHHHHHHH
EAFYNPVRRHSALDYRSPIDYERLHTTNTAA
HHHHHHHHHHCCCCCCCCCCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1482189; 11337471; 1482192 [H]