Click here to switch to the map view.

The map label for this gene is cypA [H]

Identifier: 119867555

GI number: 119867555

Start: 1622996

End: 1624249

Strand: Direct

Name: cypA [H]

Synonym: Mkms_1507

Alternate gene names: 119867555

Gene position: 1622996-1624249 (Clockwise)

Preceding gene: 119867554

Following gene: 119867556

Centisome position: 28.29

GC content: 63.4

Gene sequence:

>1254_bases
ATGACCGTGACCAGCGCCGCTCCCAACGTTTTCGATGCTGACCTCCCTACTTTCAGTTACGGCCTCACCGCCACCCCGGG
CGACATCATTGATGATGTCCGGGCGGCGCAATCGTGCTCGCCCATCGCCATCGGCCCCCTCGGCCCGGAAATCCTGTCTT
ATGATCTGGCTCGCAAAATGCTGCGCGACAACAGATTCCGGCTACCGCCCGGCATCACCCTGGCGGCGCAGGGCATCACC
TCGGGTCCATTGTTCGACAAGATCACGAGCAGCCTTCTGGGCCTGAACGGCGAACCCCACAGTCGCCTACGAAAGCTGGT
TTCCAAGGCGTTCACGCCCCGCGCGACAGCACGTCTTCAAGACACGATCCACGAGGTGGTGAATGGGCTCATCGATCGGG
TGATGGACGACGGACGGTGCGACGTCGTGACCGACATAGCGCGTCCCTACCCCACCCCGATCATCTGCGCGTTGCTCGGT
GCGCCTCGCGAAGATTGGCACCTGTTCGCGGATTGGACTGAAGAAGTCTTCAAAGCCTTCAACTTCCAAACAGAACTCAC
CTTCGATGAGTCCGAGATCATGCGCGCGTGGGGCGAACTCGACGCTTACGTCGACGACATGGTCGCCGCCCGACGAGACA
ATCTGACCGATGATCTGCTCTCCGAGCTCATTCGCGCCGAGAGCGACGGCGACCGGCTCAACCTCGACGAACTCCGCATG
CTGGTGGCCGGCTTCTTGATGGCGGGCACGGACACCACGCGCAATCAACTGGCCGCGTCGGTGCAGGTGCTCTGCGAGCA
TCCGGACCAATGGGCGAAACTGGGCGACCAACCGGAGCTTGCCATGCAGGCGGTCGAGGAAAGCATGCGCCACTCACCGG
CGGCCTGTATCGTCCCGCGGGTCGCCACCGAGGACGCCGAATTCGGCGGGTACACCTTTCCGGAGGGCACCTTCGTACTC
GTCAACACGTTCGCCGCCAACCGCGACCCAGCGATCTACGGCGATGCTGACCGCTTCGACATCGCGCGCGCGGACGTCCC
GGCAATTCTGACCTTCGGCGGCGGCGCCCATTACTGCCTCGGGGCGAACCTCGCACGCCGAGAGTTGGCGGAAGCGCTCA
CAGTTCTCACCAGACGACTCCCTGCACCGCGTCGCGTCGGTCCGGCCCCATGGAAATCCGTGCTGGGAATGACCGGTCCG
ACAACACTTCCGATCGAGTTCACGAGCGGAAGGGTTGTGACCGCGGATGCGTAG

Upstream 100 bases:

>100_bases
ATCGCCTTCACTCTTGACGAGTAGAAGCAGTGGTCATACGCTCGGTGTCAATGTGTCCGTATATCCACCGGTCTGAGCCC
CGGCGAAGGGTGAGACATCG

Downstream 100 bases:

>100_bases
TCGCGGCTGGGCGGGTGTCACACCCACCTCGGACGAAGAGGCCATTGGTCGGATCCTGGATGCGGTTGACGAAGTGGTCG
CCGAACACGGATCAGCGATA

Product: cytochrome P450

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 417; Mature: 416

Protein sequence:

>417_residues
MTVTSAAPNVFDADLPTFSYGLTATPGDIIDDVRAAQSCSPIAIGPLGPEILSYDLARKMLRDNRFRLPPGITLAAQGIT
SGPLFDKITSSLLGLNGEPHSRLRKLVSKAFTPRATARLQDTIHEVVNGLIDRVMDDGRCDVVTDIARPYPTPIICALLG
APREDWHLFADWTEEVFKAFNFQTELTFDESEIMRAWGELDAYVDDMVAARRDNLTDDLLSELIRAESDGDRLNLDELRM
LVAGFLMAGTDTTRNQLAASVQVLCEHPDQWAKLGDQPELAMQAVEESMRHSPAACIVPRVATEDAEFGGYTFPEGTFVL
VNTFAANRDPAIYGDADRFDIARADVPAILTFGGGAHYCLGANLARRELAEALTVLTRRLPAPRRVGPAPWKSVLGMTGP
TTLPIEFTSGRVVTADA

Sequences:

>Translated_417_residues
MTVTSAAPNVFDADLPTFSYGLTATPGDIIDDVRAAQSCSPIAIGPLGPEILSYDLARKMLRDNRFRLPPGITLAAQGIT
SGPLFDKITSSLLGLNGEPHSRLRKLVSKAFTPRATARLQDTIHEVVNGLIDRVMDDGRCDVVTDIARPYPTPIICALLG
APREDWHLFADWTEEVFKAFNFQTELTFDESEIMRAWGELDAYVDDMVAARRDNLTDDLLSELIRAESDGDRLNLDELRM
LVAGFLMAGTDTTRNQLAASVQVLCEHPDQWAKLGDQPELAMQAVEESMRHSPAACIVPRVATEDAEFGGYTFPEGTFVL
VNTFAANRDPAIYGDADRFDIARADVPAILTFGGGAHYCLGANLARRELAEALTVLTRRLPAPRRVGPAPWKSVLGMTGP
TTLPIEFTSGRVVTADA
>Mature_416_residues
TVTSAAPNVFDADLPTFSYGLTATPGDIIDDVRAAQSCSPIAIGPLGPEILSYDLARKMLRDNRFRLPPGITLAAQGITS
GPLFDKITSSLLGLNGEPHSRLRKLVSKAFTPRATARLQDTIHEVVNGLIDRVMDDGRCDVVTDIARPYPTPIICALLGA
PREDWHLFADWTEEVFKAFNFQTELTFDESEIMRAWGELDAYVDDMVAARRDNLTDDLLSELIRAESDGDRLNLDELRML
VAGFLMAGTDTTRNQLAASVQVLCEHPDQWAKLGDQPELAMQAVEESMRHSPAACIVPRVATEDAEFGGYTFPEGTFVLV
NTFAANRDPAIYGDADRFDIARADVPAILTFGGGAHYCLGANLARRELAEALTVLTRRLPAPRRVGPAPWKSVLGMTGPT
TLPIEFTSGRVVTADA

Specific function: Unknown

COG id: COG2124

COG function: function code Q; Cytochrome P450

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome P450 family [H]

Homologues:

Organism=Homo sapiens, GI13435391, Length=219, Percent_Identity=27.3972602739726, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI119220562, Length=208, Percent_Identity=25.4807692307692, Blast_Score=70, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI193206712, Length=190, Percent_Identity=25.7894736842105, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24642101, Length=196, Percent_Identity=30.6122448979592, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001128
- InterPro:   IPR002397
- InterPro:   IPR017972 [H]

Pfam domain/function: PF00067 p450 [H]

EC number: NA

Molecular weight: Translated: 45461; Mature: 45330

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: PS00086 CYTOCHROME_P450

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVTSAAPNVFDADLPTFSYGLTATPGDIIDDVRAAQSCSPIAIGPLGPEILSYDLARKM
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHH
LRDNRFRLPPGITLAAQGITSGPLFDKITSSLLGLNGEPHSRLRKLVSKAFTPRATARLQ
HHCCCEECCCCCEEEECCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHH
DTIHEVVNGLIDRVMDDGRCDVVTDIARPYPTPIICALLGAPREDWHLFADWTEEVFKAF
HHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCHHHHHHHCCCCHHCEEHHHHHHHHHHHH
NFQTELTFDESEIMRAWGELDAYVDDMVAARRDNLTDDLLSELIRAESDGDRLNLDELRM
CCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCHHHHHH
LVAGFLMAGTDTTRNQLAASVQVLCEHPDQWAKLGDQPELAMQAVEESMRHSPAACIVPR
HHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHCCCCEEEECC
VATEDAEFGGYTFPEGTFVLVNTFAANRDPAIYGDADRFDIARADVPAILTFGGGAHYCL
CCCCCCCCCCEECCCCCEEEEEEECCCCCCCEECCCCCCHHHHCCCCEEEEECCCCCEEC
GANLARRELAEALTVLTRRLPAPRRVGPAPWKSVLGMTGPTTLPIEFTSGRVVTADA
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCEEEEEECCCEEEEECC
>Mature Secondary Structure 
TVTSAAPNVFDADLPTFSYGLTATPGDIIDDVRAAQSCSPIAIGPLGPEILSYDLARKM
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHH
LRDNRFRLPPGITLAAQGITSGPLFDKITSSLLGLNGEPHSRLRKLVSKAFTPRATARLQ
HHCCCEECCCCCEEEECCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHH
DTIHEVVNGLIDRVMDDGRCDVVTDIARPYPTPIICALLGAPREDWHLFADWTEEVFKAF
HHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCHHHHHHHCCCCHHCEEHHHHHHHHHHHH
NFQTELTFDESEIMRAWGELDAYVDDMVAARRDNLTDDLLSELIRAESDGDRLNLDELRM
CCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCHHHHHH
LVAGFLMAGTDTTRNQLAASVQVLCEHPDQWAKLGDQPELAMQAVEESMRHSPAACIVPR
HHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHCCCCEEEECC
VATEDAEFGGYTFPEGTFVLVNTFAANRDPAIYGDADRFDIARADVPAILTFGGGAHYCL
CCCCCCCCCCEECCCCCEEEEEEECCCCCCCEECCCCCCHHHHCCCCEEEEECCCCCEEC
GANLARRELAEALTVLTRRLPAPRRVGPAPWKSVLGMTGPTTLPIEFTSGRVVTADA
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCEEEEEECCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9287000; 9308178; 9384377 [H]