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The map label for this gene is paaE [C]

Identifier: 119867426

GI number: 119867426

Start: 1476361

End: 1477491

Strand: Direct

Name: paaE [C]

Synonym: Mkms_1376

Alternate gene names: 119867426

Gene position: 1476361-1477491 (Clockwise)

Preceding gene: 119867425

Following gene: 119867427

Centisome position: 25.73

GC content: 68.79

Gene sequence:

>1131_bases
ATGGCCAAGAGTCAGATCAAAGTCTCGGCCAGAGTTGCCGACACCGTCCGTCCCCGTGTCGCTGCCAAGAACCCCGCACT
CAACGCGTTGCGCAGCATCGCCACGAAGATCACCACGCCGCTGCTGCCCGATGACTACCTGCAACTCGCCAACCCGCTGT
GGTCGGCGCGGGAGTTGCGCGGTCGCGTCATCGACGTCCGCCGGGAGACCGAGGACTCCGCCACGCTGGTGATTAAACCG
GGGTGGGGTTTCACCTTCGACTACCAGCCCGGCCAGTACATCGGCATCGGGCTGCTGATCGACGGTCGTTGGCGGTGGCG
CAGCTACTCGCTGACCTCCAGCCCGCGCAGCGGCGGCCGCACCATCACGATCACGGTCAAGGCCATGCCCGAGGGTTTCC
TGTCGACACACCTCGTCGGCGGGGTGGCACCCGGCACGATCGTGCGGTTGGCGGCCCCGCAGGGGAACTTCGTCATGCCG
GACCCGGCTCCGGCCAAGGTGCTGTTCCTCACCGGCGGTTCCGGCATCACGCCGGTGATGTCGATGCTGCGTACGCTCGT
GCGCCGCGATCAGATCACCGACGTGATCCACGTGCACTCCGCGCCGACCGAGGCCGACGTCATGTTCGGCGGTGAGTTGG
CGGCCCTGCAGGGCAGCCACGCCGGCTACCGACTGCATCTGCGGACCACGCGTACACAGGGGCGTCTGGACCTGTCCCGG
CTCGACGAGATCGTTCCGGACTGGCGGGAGCGCCAGGCCTGGGCCTGCGGACCCGAGGGCATGCTCAACGACGCCGAGAG
GGTCTGGGGGCAGGCCGGAATCGCCGACGAGTTGCACCTGGAGCGGTTCGCGGTGGCCAAGGCGGCCCCGCACGGGGCGG
GCGGCACGGTGACGTTCGCCCGCAGCGGCAAGACCGTCGACGCCGACGCGGCCACCTCGCTGATGGATGCGGGGGAGAAG
GCCGGCATCCAGATGCCCTTCGGCTGCCGGATGGGGATCTGTCAGTCGTGTGTCGTCCCCTTGGTCGACGGCCACGTACG
TGATCTGCGGACCGGCGCCGAGCACGAGGCCGGAAGCCGGATCCAGACCTGCGTGTCGGCGGCCTCCGGCGATTGCGTTC
TGGACGTTTAG

Upstream 100 bases:

>100_bases
GGACCACGATCTGGCGTGGTACGCCCCACAGGAACTGCCGTTCCTGCTCGACCTGCTCTAAAACTGGATACGGGACCGTA
GGTTACGGTACCGTAGGTTC

Downstream 100 bases:

>100_bases
TAGTTACCCACTGGTAACCTACGATCTCGTAGGTTACGCTACCGTAGGTAGAGGAAGGAGGCGCCAAGATGGCAATCACA
GACGTACCTGAATTCGCACA

Product: ferredoxin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 376; Mature: 375

Protein sequence:

>376_residues
MAKSQIKVSARVADTVRPRVAAKNPALNALRSIATKITTPLLPDDYLQLANPLWSARELRGRVIDVRRETEDSATLVIKP
GWGFTFDYQPGQYIGIGLLIDGRWRWRSYSLTSSPRSGGRTITITVKAMPEGFLSTHLVGGVAPGTIVRLAAPQGNFVMP
DPAPAKVLFLTGGSGITPVMSMLRTLVRRDQITDVIHVHSAPTEADVMFGGELAALQGSHAGYRLHLRTTRTQGRLDLSR
LDEIVPDWRERQAWACGPEGMLNDAERVWGQAGIADELHLERFAVAKAAPHGAGGTVTFARSGKTVDADAATSLMDAGEK
AGIQMPFGCRMGICQSCVVPLVDGHVRDLRTGAEHEAGSRIQTCVSAASGDCVLDV

Sequences:

>Translated_376_residues
MAKSQIKVSARVADTVRPRVAAKNPALNALRSIATKITTPLLPDDYLQLANPLWSARELRGRVIDVRRETEDSATLVIKP
GWGFTFDYQPGQYIGIGLLIDGRWRWRSYSLTSSPRSGGRTITITVKAMPEGFLSTHLVGGVAPGTIVRLAAPQGNFVMP
DPAPAKVLFLTGGSGITPVMSMLRTLVRRDQITDVIHVHSAPTEADVMFGGELAALQGSHAGYRLHLRTTRTQGRLDLSR
LDEIVPDWRERQAWACGPEGMLNDAERVWGQAGIADELHLERFAVAKAAPHGAGGTVTFARSGKTVDADAATSLMDAGEK
AGIQMPFGCRMGICQSCVVPLVDGHVRDLRTGAEHEAGSRIQTCVSAASGDCVLDV
>Mature_375_residues
AKSQIKVSARVADTVRPRVAAKNPALNALRSIATKITTPLLPDDYLQLANPLWSARELRGRVIDVRRETEDSATLVIKPG
WGFTFDYQPGQYIGIGLLIDGRWRWRSYSLTSSPRSGGRTITITVKAMPEGFLSTHLVGGVAPGTIVRLAAPQGNFVMPD
PAPAKVLFLTGGSGITPVMSMLRTLVRRDQITDVIHVHSAPTEADVMFGGELAALQGSHAGYRLHLRTTRTQGRLDLSRL
DEIVPDWRERQAWACGPEGMLNDAERVWGQAGIADELHLERFAVAKAAPHGAGGTVTFARSGKTVDADAATSLMDAGEKA
GIQMPFGCRMGICQSCVVPLVDGHVRDLRTGAEHEAGSRIQTCVSAASGDCVLDV

Specific function: This is an electron transfer partner for desA3 [H]

COG id: COG1018

COG function: function code C; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Escherichia coli, GI1787658, Length=312, Percent_Identity=26.6025641025641, Blast_Score=101, Evalue=7e-23,
Organism=Escherichia coli, GI1787098, Length=328, Percent_Identity=27.7439024390244, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1788903, Length=216, Percent_Identity=30.5555555555556, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1788104, Length=288, Percent_Identity=30.5555555555556, Blast_Score=76, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6323510, Length=199, Percent_Identity=26.6331658291457, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR017927
- InterPro:   IPR001041
- InterPro:   IPR001709
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR001221
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00111 Fer2; PF00175 NAD_binding_1 [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 40424; Mature: 40293

Theoretical pI: Translated: 8.60; Mature: 8.60

Prosite motif: PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKSQIKVSARVADTVRPRVAAKNPALNALRSIATKITTPLLPDDYLQLANPLWSARELR
CCCCCEEEEEHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHC
GRVIDVRRETEDSATLVIKPGWGFTFDYQPGQYIGIGLLIDGRWRWRSYSLTSSPRSGGR
CEEEEEEECCCCCEEEEEECCCCEEEECCCCCEEEEEEEECCCEEEEEEECCCCCCCCCE
TITITVKAMPEGFLSTHLVGGVAPGTIVRLAAPQGNFVMPDPAPAKVLFLTGGSGITPVM
EEEEEEEECCCCHHHHHHHCCCCCCEEEEEECCCCCEECCCCCCCEEEEEECCCCHHHHH
SMLRTLVRRDQITDVIHVHSAPTEADVMFGGELAALQGSHAGYRLHLRTTRTQGRLDLSR
HHHHHHHHHHHHHHEEEECCCCCCCEEEECCEEEEECCCCCCEEEEEEEECCCCCCCHHH
LDEIVPDWRERQAWACGPEGMLNDAERVWGQAGIADELHLERFAVAKAAPHGAGGTVTFA
HHHHCCCHHHCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCEEEEE
RSGKTVDADAATSLMDAGEKAGIQMPFGCRMGICQSCVVPLVDGHVRDLRTGAEHEAGSR
CCCCEECHHHHHHHHHCHHHCCEECCCCCCHHHHHHHHHHHHCCHHHHHHCCCCCCCCHH
IQTCVSAASGDCVLDV
HHHHHHHCCCCEEEEC
>Mature Secondary Structure 
AKSQIKVSARVADTVRPRVAAKNPALNALRSIATKITTPLLPDDYLQLANPLWSARELR
CCCCEEEEEHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHC
GRVIDVRRETEDSATLVIKPGWGFTFDYQPGQYIGIGLLIDGRWRWRSYSLTSSPRSGGR
CEEEEEEECCCCCEEEEEECCCCEEEECCCCCEEEEEEEECCCEEEEEEECCCCCCCCCE
TITITVKAMPEGFLSTHLVGGVAPGTIVRLAAPQGNFVMPDPAPAKVLFLTGGSGITPVM
EEEEEEEECCCCHHHHHHHCCCCCCEEEEEECCCCCEECCCCCCCEEEEEECCCCHHHHH
SMLRTLVRRDQITDVIHVHSAPTEADVMFGGELAALQGSHAGYRLHLRTTRTQGRLDLSR
HHHHHHHHHHHHHHEEEECCCCCCCEEEECCEEEEECCCCCCEEEEEEEECCCCCCCHHH
LDEIVPDWRERQAWACGPEGMLNDAERVWGQAGIADELHLERFAVAKAAPHGAGGTVTFA
HHHHCCCHHHCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCEEEEE
RSGKTVDADAATSLMDAGEKAGIQMPFGCRMGICQSCVVPLVDGHVRDLRTGAEHEAGSR
CCCCEECHHHHHHHHHCHHHCCEECCCCCCHHHHHHHHHHHHCCHHHHHHCCCCCCCCHH
IQTCVSAASGDCVLDV
HHHHHHHCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: FAD [C]

Metal ions: Iron-Sulfur [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]