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The map label for this gene is fadE25 [H]

Identifier: 119867367

GI number: 119867367

Start: 1408844

End: 1410010

Strand: Direct

Name: fadE25 [H]

Synonym: Mkms_1317

Alternate gene names: 119867367

Gene position: 1408844-1410010 (Clockwise)

Preceding gene: 119867366

Following gene: 119867373

Centisome position: 24.56

GC content: 67.44

Gene sequence:

>1167_bases
ATGGCTGGTTGGACCGGAAACCCGTCCTTCGACGTGTTCGGTTTGCCCGAGGAACACCAGGAGCTGCGCGCGGCGATCCG
CGCACTCGCCGAGAAGGAGATCGCCCCGTACGCGGCGGATGTCGACGAGCAGATGCGGTTCCCGCAGGAGGCGTTGGACG
CTCTCAACGCCTCGGGGTTCAACGCGGTGCACGTACCCGAGGAGTACGGCGGCCAGGGCGCCGATTCGGTGGCGGCGTGC
ATCGTCATCGAGGAGGTCGCGCGGGTCGACGCGTCGGCGTCGCTGATCCCCGCGGTCAACAAGCTCGGCACCATGGGCCT
GATCCTGCGCGGCTCCGAGGAGTTGAAGCAGAAGGTGCTGCCGGACCTCGTCGAGGGCCAGTTGGCGTCCTATGCGCTGT
CCGAACGTGAGGCGGGCAGCGACGCCGCGTCGATGCGCACCCGCGCCAAGGCCGACGGTGACGACTGGATCCTCAACGGC
GCCAAGGCATGGATCACCAACGGCGGCAAGTCGTCCTGGTACACCGTGATGGCGGTGACCGATCCCGACAAGGGCGCCAA
CGGCATCTCGGCGTTCATGGTGCACATCGACGACGAGGGTTTCACCGTCGGCCCCAAGGAGCGCAAGCTCGGCATCAAGG
GTTCGCCCACGACCGAGCTGTACTTCGAGAACTGCCGCATCCCGGGGGACCGGATCGTCGGCGAGCCGGGCACCGGCTTC
AAGACCGCACTCGCGACGCTCGACCACACCCGCCCGACCATCGGCGCCCAGGCCGTCGGCATCGCTCAGGGCGCGGTCGA
CGCGGCGATCGCCTACACCAAGGACCGCAAGCAGTTCGGGACGTCGATCAGCGACTTCCAGGGTGTGCAGTTCATGCTCG
CCGACATGGCGATGAAGGTGGAGGCCGCCCGGTTGATGGTGTACTCGGCCGCCGCCCGCGCCGAACGCGGTGAGGGCAAT
CTCGGCTTCATCTCCGCGGCGTCGAAGTGCTTCGCCTCCGACGTCGCGATGGAGGTGACCACCGACGCGGTGCAGCTGTT
CGGCGGCGCCGGCTACACCGTCGACTTCCCGGTCGAGCGGATGATGCGTGACGCCAAGATCACCCAGATCTACGAGGGCA
CGAATCAGATTCAGCGCGTTGTGATGTCGCGGGCGCTGCTGCGCTGA

Upstream 100 bases:

>100_bases
CGAGCAGATGGTGCTCGAGAAGGATGAAGCGCTGCGGAACCGGCTACTCGGTGCGGACTGAACGCAGGTAAAGTTACCGG
TGAGTAGCAAGGAGGCCACG

Downstream 100 bases:

>100_bases
GCCGTCACGGTCAGTAGGCGCCGCGGCCGCGGGCCACGGTCATCGCGGTCCTGGCCAGGATTCGCAGGTCCTGATCCATC
GACCAGTTCTCCACGTAGTA

Product: acyl-CoA dehydrogenase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 388; Mature: 387

Protein sequence:

>388_residues
MAGWTGNPSFDVFGLPEEHQELRAAIRALAEKEIAPYAADVDEQMRFPQEALDALNASGFNAVHVPEEYGGQGADSVAAC
IVIEEVARVDASASLIPAVNKLGTMGLILRGSEELKQKVLPDLVEGQLASYALSEREAGSDAASMRTRAKADGDDWILNG
AKAWITNGGKSSWYTVMAVTDPDKGANGISAFMVHIDDEGFTVGPKERKLGIKGSPTTELYFENCRIPGDRIVGEPGTGF
KTALATLDHTRPTIGAQAVGIAQGAVDAAIAYTKDRKQFGTSISDFQGVQFMLADMAMKVEAARLMVYSAAARAERGEGN
LGFISAASKCFASDVAMEVTTDAVQLFGGAGYTVDFPVERMMRDAKITQIYEGTNQIQRVVMSRALLR

Sequences:

>Translated_388_residues
MAGWTGNPSFDVFGLPEEHQELRAAIRALAEKEIAPYAADVDEQMRFPQEALDALNASGFNAVHVPEEYGGQGADSVAAC
IVIEEVARVDASASLIPAVNKLGTMGLILRGSEELKQKVLPDLVEGQLASYALSEREAGSDAASMRTRAKADGDDWILNG
AKAWITNGGKSSWYTVMAVTDPDKGANGISAFMVHIDDEGFTVGPKERKLGIKGSPTTELYFENCRIPGDRIVGEPGTGF
KTALATLDHTRPTIGAQAVGIAQGAVDAAIAYTKDRKQFGTSISDFQGVQFMLADMAMKVEAARLMVYSAAARAERGEGN
LGFISAASKCFASDVAMEVTTDAVQLFGGAGYTVDFPVERMMRDAKITQIYEGTNQIQRVVMSRALLR
>Mature_387_residues
AGWTGNPSFDVFGLPEEHQELRAAIRALAEKEIAPYAADVDEQMRFPQEALDALNASGFNAVHVPEEYGGQGADSVAACI
VIEEVARVDASASLIPAVNKLGTMGLILRGSEELKQKVLPDLVEGQLASYALSEREAGSDAASMRTRAKADGDDWILNGA
KAWITNGGKSSWYTVMAVTDPDKGANGISAFMVHIDDEGFTVGPKERKLGIKGSPTTELYFENCRIPGDRIVGEPGTGFK
TALATLDHTRPTIGAQAVGIAQGAVDAAIAYTKDRKQFGTSISDFQGVQFMLADMAMKVEAARLMVYSAAARAERGEGNL
GFISAASKCFASDVAMEVTTDAVQLFGGAGYTVDFPVERMMRDAKITQIYEGTNQIQRVVMSRALLR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=378, Percent_Identity=46.2962962962963, Blast_Score=317, Evalue=1e-86,
Organism=Homo sapiens, GI187960098, Length=376, Percent_Identity=40.6914893617021, Blast_Score=291, Evalue=7e-79,
Organism=Homo sapiens, GI4557231, Length=376, Percent_Identity=40.6914893617021, Blast_Score=291, Evalue=8e-79,
Organism=Homo sapiens, GI4501859, Length=373, Percent_Identity=39.142091152815, Blast_Score=281, Evalue=6e-76,
Organism=Homo sapiens, GI21361497, Length=352, Percent_Identity=38.9204545454545, Blast_Score=236, Evalue=2e-62,
Organism=Homo sapiens, GI226958412, Length=386, Percent_Identity=34.7150259067358, Blast_Score=229, Evalue=3e-60,
Organism=Homo sapiens, GI7656849, Length=377, Percent_Identity=34.4827586206897, Blast_Score=228, Evalue=9e-60,
Organism=Homo sapiens, GI226958414, Length=355, Percent_Identity=35.4929577464789, Blast_Score=212, Evalue=4e-55,
Organism=Homo sapiens, GI76496475, Length=343, Percent_Identity=37.0262390670554, Blast_Score=208, Evalue=6e-54,
Organism=Homo sapiens, GI4557235, Length=343, Percent_Identity=37.0262390670554, Blast_Score=208, Evalue=7e-54,
Organism=Homo sapiens, GI4501857, Length=377, Percent_Identity=31.2997347480106, Blast_Score=195, Evalue=5e-50,
Organism=Homo sapiens, GI4503943, Length=370, Percent_Identity=24.3243243243243, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI7669494, Length=356, Percent_Identity=23.876404494382, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI211971008, Length=298, Percent_Identity=28.5234899328859, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI48976061, Length=298, Percent_Identity=28.5234899328859, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI38505218, Length=295, Percent_Identity=22.7118644067797, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI87081958, Length=381, Percent_Identity=31.758530183727, Blast_Score=155, Evalue=5e-39,
Organism=Escherichia coli, GI1786223, Length=381, Percent_Identity=29.6587926509186, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI87081702, Length=365, Percent_Identity=25.4794520547945, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI87082384, Length=273, Percent_Identity=24.9084249084249, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17570075, Length=379, Percent_Identity=43.0079155672823, Blast_Score=317, Evalue=8e-87,
Organism=Caenorhabditis elegans, GI17508101, Length=367, Percent_Identity=42.2343324250681, Blast_Score=295, Evalue=4e-80,
Organism=Caenorhabditis elegans, GI17534899, Length=380, Percent_Identity=39.4736842105263, Blast_Score=286, Evalue=2e-77,
Organism=Caenorhabditis elegans, GI17569725, Length=379, Percent_Identity=39.3139841688654, Blast_Score=285, Evalue=3e-77,
Organism=Caenorhabditis elegans, GI17506239, Length=386, Percent_Identity=39.3782383419689, Blast_Score=275, Evalue=2e-74,
Organism=Caenorhabditis elegans, GI17533517, Length=376, Percent_Identity=38.031914893617, Blast_Score=260, Evalue=1e-69,
Organism=Caenorhabditis elegans, GI17538396, Length=379, Percent_Identity=37.467018469657, Blast_Score=254, Evalue=4e-68,
Organism=Caenorhabditis elegans, GI71990804, Length=279, Percent_Identity=43.7275985663082, Blast_Score=230, Evalue=1e-60,
Organism=Caenorhabditis elegans, GI71985184, Length=382, Percent_Identity=35.3403141361257, Blast_Score=217, Evalue=9e-57,
Organism=Caenorhabditis elegans, GI32563615, Length=237, Percent_Identity=43.8818565400844, Blast_Score=199, Evalue=3e-51,
Organism=Caenorhabditis elegans, GI71982178, Length=278, Percent_Identity=34.5323741007194, Blast_Score=183, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI71985192, Length=316, Percent_Identity=35.7594936708861, Blast_Score=179, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI17505929, Length=377, Percent_Identity=29.7082228116711, Blast_Score=170, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI17551932, Length=373, Percent_Identity=30.2949061662198, Blast_Score=169, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI17531909, Length=236, Percent_Identity=34.7457627118644, Blast_Score=143, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17534353, Length=377, Percent_Identity=25.7294429708223, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17531913, Length=171, Percent_Identity=32.1637426900585, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI86563381, Length=322, Percent_Identity=26.7080745341615, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI86563383, Length=322, Percent_Identity=26.7080745341615, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17562446, Length=349, Percent_Identity=26.647564469914, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24660351, Length=384, Percent_Identity=40.1041666666667, Blast_Score=290, Evalue=1e-78,
Organism=Drosophila melanogaster, GI21356377, Length=376, Percent_Identity=39.6276595744681, Blast_Score=268, Evalue=4e-72,
Organism=Drosophila melanogaster, GI24646207, Length=375, Percent_Identity=40.2666666666667, Blast_Score=265, Evalue=4e-71,
Organism=Drosophila melanogaster, GI24666513, Length=391, Percent_Identity=36.8286445012788, Blast_Score=254, Evalue=8e-68,
Organism=Drosophila melanogaster, GI21355753, Length=388, Percent_Identity=35.5670103092784, Blast_Score=223, Evalue=1e-58,
Organism=Drosophila melanogaster, GI281363737, Length=393, Percent_Identity=34.6055979643766, Blast_Score=208, Evalue=4e-54,
Organism=Drosophila melanogaster, GI19920834, Length=379, Percent_Identity=28.7598944591029, Blast_Score=135, Evalue=6e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 41460; Mature: 41329

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGWTGNPSFDVFGLPEEHQELRAAIRALAEKEIAPYAADVDEQMRFPQEALDALNASGF
CCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCHHHHHHHCCCCC
NAVHVPEEYGGQGADSVAACIVIEEVARVDASASLIPAVNKLGTMGLILRGSEELKQKVL
CEEECCHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCEEEEEECHHHHHHHHH
PDLVEGQLASYALSEREAGSDAASMRTRAKADGDDWILNGAKAWITNGGKSSWYTVMAVT
HHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCEEECCCEEEEECCCCCCEEEEEEEE
DPDKGANGISAFMVHIDDEGFTVGPKERKLGIKGSPTTELYFENCRIPGDRIVGEPGTGF
CCCCCCCCEEEEEEEECCCCCEECCHHHCCCCCCCCCCEEEEECCCCCCCCEECCCCCCH
KTALATLDHTRPTIGAQAVGIAQGAVDAAIAYTKDRKQFGTSISDFQGVQFMLADMAMKV
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
EAARLMVYSAAARAERGEGNLGFISAASKCFASDVAMEVTTDAVQLFGGAGYTVDFPVER
HHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCHHH
MMRDAKITQIYEGTNQIQRVVMSRALLR
HHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AGWTGNPSFDVFGLPEEHQELRAAIRALAEKEIAPYAADVDEQMRFPQEALDALNASGF
CCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCHHHHHHHCCCCC
NAVHVPEEYGGQGADSVAACIVIEEVARVDASASLIPAVNKLGTMGLILRGSEELKQKVL
CEEECCHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCEEEEEECHHHHHHHHH
PDLVEGQLASYALSEREAGSDAASMRTRAKADGDDWILNGAKAWITNGGKSSWYTVMAVT
HHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCEEECCCEEEEECCCCCCEEEEEEEE
DPDKGANGISAFMVHIDDEGFTVGPKERKLGIKGSPTTELYFENCRIPGDRIVGEPGTGF
CCCCCCCCEEEEEEEECCCCCEECCHHHCCCCCCCCCCEEEEECCCCCCCCEECCCCCCH
KTALATLDHTRPTIGAQAVGIAQGAVDAAIAYTKDRKQFGTSISDFQGVQFMLADMAMKV
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
EAARLMVYSAAARAERGEGNLGFISAASKCFASDVAMEVTTDAVQLFGGAGYTVDFPVER
HHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCHHH
MMRDAKITQIYEGTNQIQRVVMSRALLR
HHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]