Click here to switch to the map view.

The map label for this gene is sdhB [H]

Identifier: 119867294

GI number: 119867294

Start: 1330232

End: 1331008

Strand: Reverse

Name: sdhB [H]

Synonym: Mkms_1244

Alternate gene names: 119867294

Gene position: 1331008-1330232 (Counterclockwise)

Preceding gene: 119867295

Following gene: 119867291

Centisome position: 23.2

GC content: 66.54

Gene sequence:

>777_bases
ATGAGCGCACCTGCAATCGAGAAGAACGAAGCCACCACACCGCCGATGCCCGAGGGCGCGGTCATGGTGACGCTCAAGAT
CGCCCGGTTCAACCCGGAGGCACCTGACGACGCCGGCTTCCAGAGCTTCCGCGTCCCGTGCCTGCCCACCGACCGGCTGC
TCAACCTGCTGCACTACGTGAAGTGGTACCTCGACGGCACGCTGACGTTCCGCCGGTCCTGCGCGCACGGCGTGTGTGGC
TCGGACGCGATGCGCATCAACGGGGTCAACCGGCTGGCGTGCAAGGTGCTGATGCGCGACATGCTGCCGAAGAACCCGAA
GAAGCAGCTCACCATCACCATCGAGCCGATCCGCGGCCTGCCCGTGGAGAAGGACCTCGTGGTCGACATGGAGCCGTTCT
TCGACGCCTACCGCGCGGTCAAGCCCTACCTGATGACCAGCGGTAACCAGCCCACCAAGGAACGCATCCAGAGCCAGGTC
GACCGGGCCCGGTACGACGACACCACCAAGTGCATCCTGTGCGCGGCGTGCACCACCAGCTGCCCGATCTACTGGACCGA
GGGCAGCTATGTGGGCCCGGCGGCGATCGTCAACGCCCACCGGTTCATCTTCGACAGCCGCGACGAGGGTGCGGCCGAGC
GTCTCGACATCCTCAACGACGCCGACGGTGTGTGGCGCTGCCGCACGACGTTCAACTGCACCGAGGCCTGCCCGCGCGGC
ATCCAGATCACCCAGGCGATCCAGGAGGTCAAGCGCGCGCTGATGTTCGCCCGCTGA

Upstream 100 bases:

>100_bases
CAGACCCGCTACGAGCCGATGGAACGGAAGTACTGACGATGAGACGCTTGCGCCGCGACGAGCCCTCGGGCGAGGAGCGA
TCGATGAAGAGCGAGAACCG

Downstream 100 bases:

>100_bases
CCACGGCTCTCCCGAGACTGCGGGGAGATCGCGAGAATCGACAGATTCGCGATCTCCCCGCAGTTTCGGCGTTGTGGGGG
GGGTCACGCCGACTCGTCGG

Product: succinate dehydrogenase iron-sulfur subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:

>258_residues
MSAPAIEKNEATTPPMPEGAVMVTLKIARFNPEAPDDAGFQSFRVPCLPTDRLLNLLHYVKWYLDGTLTFRRSCAHGVCG
SDAMRINGVNRLACKVLMRDMLPKNPKKQLTITIEPIRGLPVEKDLVVDMEPFFDAYRAVKPYLMTSGNQPTKERIQSQV
DRARYDDTTKCILCAACTTSCPIYWTEGSYVGPAAIVNAHRFIFDSRDEGAAERLDILNDADGVWRCRTTFNCTEACPRG
IQITQAIQEVKRALMFAR

Sequences:

>Translated_258_residues
MSAPAIEKNEATTPPMPEGAVMVTLKIARFNPEAPDDAGFQSFRVPCLPTDRLLNLLHYVKWYLDGTLTFRRSCAHGVCG
SDAMRINGVNRLACKVLMRDMLPKNPKKQLTITIEPIRGLPVEKDLVVDMEPFFDAYRAVKPYLMTSGNQPTKERIQSQV
DRARYDDTTKCILCAACTTSCPIYWTEGSYVGPAAIVNAHRFIFDSRDEGAAERLDILNDADGVWRCRTTFNCTEACPRG
IQITQAIQEVKRALMFAR
>Mature_257_residues
SAPAIEKNEATTPPMPEGAVMVTLKIARFNPEAPDDAGFQSFRVPCLPTDRLLNLLHYVKWYLDGTLTFRRSCAHGVCGS
DAMRINGVNRLACKVLMRDMLPKNPKKQLTITIEPIRGLPVEKDLVVDMEPFFDAYRAVKPYLMTSGNQPTKERIQSQVD
RARYDDTTKCILCAACTTSCPIYWTEGSYVGPAAIVNAHRFIFDSRDEGAAERLDILNDADGVWRCRTTFNCTEACPRGI
QITQAIQEVKRALMFAR

Specific function: Two Distinct, Membrane-Bound, FAD-Containing Enzymes Are Responsible For The Catalysis Of Fumarate And Succinate Interconversion; The Fumarate Reductase Is Used In Anaerobic Growth, And The Succinate Dehydrogenase Is Used In Aerobic Growth. [C]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI115387094, Length=235, Percent_Identity=40.4255319148936, Blast_Score=167, Evalue=1e-41,
Organism=Escherichia coli, GI1786943, Length=240, Percent_Identity=41.25, Blast_Score=179, Evalue=2e-46,
Organism=Escherichia coli, GI1790596, Length=232, Percent_Identity=36.6379310344828, Blast_Score=161, Evalue=5e-41,
Organism=Caenorhabditis elegans, GI17533915, Length=241, Percent_Identity=40.2489626556017, Blast_Score=162, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6322987, Length=242, Percent_Identity=40.9090909090909, Blast_Score=175, Evalue=5e-45,
Organism=Drosophila melanogaster, GI17137106, Length=242, Percent_Identity=41.7355371900826, Blast_Score=172, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24643156, Length=239, Percent_Identity=39.3305439330544, Blast_Score=160, Evalue=6e-40,

Paralogues:

None

Copy number: 480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006058
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 28942; Mature: 28811

Theoretical pI: Translated: 8.03; Mature: 8.03

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
7.8 %Cys+Met (Translated Protein)
4.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
7.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAPAIEKNEATTPPMPEGAVMVTLKIARFNPEAPDDAGFQSFRVPCLPTDRLLNLLHYV
CCCCCCCCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
KWYLDGTLTFRRSCAHGVCGSDAMRINGVNRLACKVLMRDMLPKNPKKQLTITIEPIRGL
HHHHCCHHHHHHHHHCCCCCCCCEEECCHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCC
PVEKDLVVDMEPFFDAYRAVKPYLMTSGNQPTKERIQSQVDRARYDDTTKCILCAACTTS
CCCCCEEEECHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEEEHHCC
CPIYWTEGSYVGPAAIVNAHRFIFDSRDEGAAERLDILNDADGVWRCRTTFNCTEACPRG
CCEEECCCCCCCHHHHHHHHHHEECCCCCCHHHHHHHHCCCCCEEEEECCCCHHHHCCCC
IQITQAIQEVKRALMFAR
CHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SAPAIEKNEATTPPMPEGAVMVTLKIARFNPEAPDDAGFQSFRVPCLPTDRLLNLLHYV
CCCCCCCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
KWYLDGTLTFRRSCAHGVCGSDAMRINGVNRLACKVLMRDMLPKNPKKQLTITIEPIRGL
HHHHCCHHHHHHHHHCCCCCCCCEEECCHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCC
PVEKDLVVDMEPFFDAYRAVKPYLMTSGNQPTKERIQSQVDRARYDDTTKCILCAACTTS
CCCCCEEEECHHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEEEHHCC
CPIYWTEGSYVGPAAIVNAHRFIFDSRDEGAAERLDILNDADGVWRCRTTFNCTEACPRG
CCEEECCCCCCCHHHHHHHHHHEECCCCCCHHHHHHHHCCCCCEEEEECCCCHHHHCCCC
IQITQAIQEVKRALMFAR
CHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA