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The map label for this gene is metX

Identifier: 119867274

GI number: 119867274

Start: 1309131

End: 1310252

Strand: Reverse

Name: metX

Synonym: Mkms_1224

Alternate gene names: 119867274

Gene position: 1310252-1309131 (Counterclockwise)

Preceding gene: 119867275

Following gene: 119867273

Centisome position: 22.84

GC content: 72.28

Gene sequence:

>1122_bases
TTGAAGAGCCCCGCCGTGCCCGCCCTCGACCTGCCCGCCGAGGGTGAGACCGGCGTGGTCGACATCGGCCCGCTGACCCT
GGAGAGCGGCGCGGTCATCGACGACGTGTCGATCGCCGTCCAGCGCTGGGGTGAGCTCTCCCCCAACCGCGACAACGTCG
TGATGGTGCTGCATGCGCTCACCGGTGACTCGCACGTCACCGGACCGGCCGGCCCCGACCATCCCACCCCGGGCTGGTGG
GACGGCGTCGCCGGGCCGGGAGCCCCGATCGACACCGACCGCTGGTGCGCGGTGTCGACGAACGTCCTCGGCGGCTGCCG
TGGGTCGACCGGCCCGTCGTCGATCGCTCCCGACGGCCGGCCGTACGGTTCGCGGTTCCCCGCGGTGACGATCCGCGACC
AGGTCACCGCGGACCTCGCCGCGCTCGAGGCGCTGGGCATCACCGAGGTCGCCGCGGTGGTGGGCGGATCCATGGGCGGC
GCGCGTGCGCTGGAGTGGATCGTCGGCCATCCGGCCACCGTGCGTTCGGCGCTGATCCTCGCCGTCGGCGCCCGCGCCAC
CGCCGACCAGATCGGCACGCAGAGCACCCAGGTCGCCGCGATCAAGGCCGATCCCGACTGGTGCGGCGGCGACTACCACG
ACACCGGTCGCGTGCCGTCCACCGGTCTGGCGATCGCCCGCCGCTTCGCCCACCTGACCTACCGCGGTGAAGTCGAACTC
GACGACCGGTTCGGCAACCACGCCCAGGGTGACGAGAGCCCGACCGACGGCGGCCGGTACGCGGTGCAGAGTTATCTGGA
GTACCAGGGCGCCAAGCTGGTCGAGCGGTTCGACGCAGGCACCTACGTCACGCTGACCGACGCGTTGTCGAGCCACGACG
TGGGTCGCGGCCGCGGAGGCGTGCGCGCTGCGCTGCAGGGTTGCCGGGTGCCCACGATCGTCGGCGGCGTCACCTCCGAC
CGGCTCTACCCCCTGCGGCTGCAGCAGGAGTTGGCCGAACTGCTGCCCGGCTGTACCGGTCTGGACGTGGTCGATTCGGT
CTACGGCCACGACGGGTTCCTGGTCGAGACGGAGGCCGTCGGCAAGCTCATCCGGCGCACACTGGAGTTGGCGGAGCGGT
GA

Upstream 100 bases:

>100_bases
CGGCATCGAGGGCATCGACGACATCCTCGCCGACCTCGAGCAGGGGTTCGCGGCTGCCAAGGCGATCTCCTGAAGTTCGA
AGAGACAGCAAGTGACGATT

Downstream 100 bases:

>100_bases
CCGATCCGTCTCTTTCGTTCGGCGAGCAGGCCGCGGCCTACGAGCGGGGCAGGCCGTCGTATCCGCCGGAAGCGATCGAC
TGGCTGCTCCCGCGTGGCGC

Product: homoserine O-acetyltransferase

Products: NA

Alternate protein names: Homoserine O-trans-acetylase; HTA; Homoserine transacetylase

Number of amino acids: Translated: 373; Mature: 373

Protein sequence:

>373_residues
MKSPAVPALDLPAEGETGVVDIGPLTLESGAVIDDVSIAVQRWGELSPNRDNVVMVLHALTGDSHVTGPAGPDHPTPGWW
DGVAGPGAPIDTDRWCAVSTNVLGGCRGSTGPSSIAPDGRPYGSRFPAVTIRDQVTADLAALEALGITEVAAVVGGSMGG
ARALEWIVGHPATVRSALILAVGARATADQIGTQSTQVAAIKADPDWCGGDYHDTGRVPSTGLAIARRFAHLTYRGEVEL
DDRFGNHAQGDESPTDGGRYAVQSYLEYQGAKLVERFDAGTYVTLTDALSSHDVGRGRGGVRAALQGCRVPTIVGGVTSD
RLYPLRLQQELAELLPGCTGLDVVDSVYGHDGFLVETEAVGKLIRRTLELAER

Sequences:

>Translated_373_residues
MKSPAVPALDLPAEGETGVVDIGPLTLESGAVIDDVSIAVQRWGELSPNRDNVVMVLHALTGDSHVTGPAGPDHPTPGWW
DGVAGPGAPIDTDRWCAVSTNVLGGCRGSTGPSSIAPDGRPYGSRFPAVTIRDQVTADLAALEALGITEVAAVVGGSMGG
ARALEWIVGHPATVRSALILAVGARATADQIGTQSTQVAAIKADPDWCGGDYHDTGRVPSTGLAIARRFAHLTYRGEVEL
DDRFGNHAQGDESPTDGGRYAVQSYLEYQGAKLVERFDAGTYVTLTDALSSHDVGRGRGGVRAALQGCRVPTIVGGVTSD
RLYPLRLQQELAELLPGCTGLDVVDSVYGHDGFLVETEAVGKLIRRTLELAER
>Mature_373_residues
MKSPAVPALDLPAEGETGVVDIGPLTLESGAVIDDVSIAVQRWGELSPNRDNVVMVLHALTGDSHVTGPAGPDHPTPGWW
DGVAGPGAPIDTDRWCAVSTNVLGGCRGSTGPSSIAPDGRPYGSRFPAVTIRDQVTADLAALEALGITEVAAVVGGSMGG
ARALEWIVGHPATVRSALILAVGARATADQIGTQSTQVAAIKADPDWCGGDYHDTGRVPSTGLAIARRFAHLTYRGEVEL
DDRFGNHAQGDESPTDGGRYAVQSYLEYQGAKLVERFDAGTYVTLTDALSSHDVGRGRGGVRAALQGCRVPTIVGGVTSD
RLYPLRLQQELAELLPGCTGLDVVDSVYGHDGFLVETEAVGKLIRRTLELAER

Specific function: Unknown

COG id: COG2021

COG function: function code E; Homoserine acetyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. HTA family

Homologues:

Organism=Saccharomyces cerevisiae, GI6324052, Length=260, Percent_Identity=33.4615384615385, Blast_Score=137, Evalue=4e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): METX_MYCSK (A1UC78)

Other databases:

- EMBL:   CP000518
- RefSeq:   YP_937226.1
- ProteinModelPortal:   A1UC78
- SMR:   A1UC78
- STRING:   A1UC78
- EnsemblBacteria:   EBMYCT00000054777
- GeneID:   4614420
- GenomeReviews:   CP000518_GR
- KEGG:   mkm:Mkms_1224
- eggNOG:   COG2021
- GeneTree:   EBGT00050000016704
- HOGENOM:   HBG692920
- OMA:   VSFTSDW
- ProtClustDB:   PRK00175
- BioCyc:   MSP189918:MKMS_1224-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00296
- InterPro:   IPR000073
- InterPro:   IPR008220
- PIRSF:   PIRSF000443
- TIGRFAMs:   TIGR01392

Pfam domain/function: PF00561 Abhydrolase_1

EC number: =2.3.1.31

Molecular weight: Translated: 38960; Mature: 38960

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: ACT_SITE 157-157 ACT_SITE 350-350

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSPAVPALDLPAEGETGVVDIGPLTLESGAVIDDVSIAVQRWGELSPNRDNVVMVLHAL
CCCCCCCEECCCCCCCCCEEECCCEEECCCCEEHHHHHHHHHHCCCCCCCCCEEEEEEEE
TGDSHVTGPAGPDHPTPGWWDGVAGPGAPIDTDRWCAVSTNVLGGCRGSTGPSSIAPDGR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCC
PYGSRFPAVTIRDQVTADLAALEALGITEVAAVVGGSMGGARALEWIVGHPATVRSALIL
CCCCCCCEEEEHHHHHHHHHHHHHHCHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHH
AVGARATADQIGTQSTQVAAIKADPDWCGGDYHDTGRVPSTGLAIARRFAHLTYRGEVEL
HCCCCCCHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHEEEECCEEE
DDRFGNHAQGDESPTDGGRYAVQSYLEYQGAKLVERFDAGTYVTLTDALSSHDVGRGRGG
HHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHCCCCCCCCCH
VRAALQGCRVPTIVGGVTSDRLYPLRLQQELAELLPGCTGLDVVDSVYGHDGFLVETEAV
HHHHHHCCCCCEEECCCCCCCEEHHHHHHHHHHHCCCCCCHHHHHHHHCCCCEEEEHHHH
GKLIRRTLELAER
HHHHHHHHHHHCC
>Mature Secondary Structure
MKSPAVPALDLPAEGETGVVDIGPLTLESGAVIDDVSIAVQRWGELSPNRDNVVMVLHAL
CCCCCCCEECCCCCCCCCEEECCCEEECCCCEEHHHHHHHHHHCCCCCCCCCEEEEEEEE
TGDSHVTGPAGPDHPTPGWWDGVAGPGAPIDTDRWCAVSTNVLGGCRGSTGPSSIAPDGR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCC
PYGSRFPAVTIRDQVTADLAALEALGITEVAAVVGGSMGGARALEWIVGHPATVRSALIL
CCCCCCCEEEEHHHHHHHHHHHHHHCHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHHH
AVGARATADQIGTQSTQVAAIKADPDWCGGDYHDTGRVPSTGLAIARRFAHLTYRGEVEL
HCCCCCCHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHEEEECCEEE
DDRFGNHAQGDESPTDGGRYAVQSYLEYQGAKLVERFDAGTYVTLTDALSSHDVGRGRGG
HHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHCCCCCCCCCH
VRAALQGCRVPTIVGGVTSDRLYPLRLQQELAELLPGCTGLDVVDSVYGHDGFLVETEAV
HHHHHHCCCCCEEECCCCCCCEEHHHHHHHHHHHCCCCCCHHHHHHHHCCCCEEEEHHHH
GKLIRRTLELAER
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA