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The map label for this gene is pamO [H]

Identifier: 119866385

GI number: 119866385

Start: 365799

End: 367421

Strand: Direct

Name: pamO [H]

Synonym: Mkms_0330

Alternate gene names: 119866385

Gene position: 365799-367421 (Clockwise)

Preceding gene: 119866376

Following gene: 119866386

Centisome position: 6.38

GC content: 65.25

Gene sequence:

>1623_bases
GTGGACACCTCGGCTGATCAGCTGCCCAACCAGGTCGATGCGGTGGTGGTCGGCGCCGGCTTCGCGGGCCTGTACGCACT
GCACAAGCTGCGCTCGCAGGGGTTGACCGTCCGGGTGTTCGAGGCCGCCCCGGACGTCGGTGGCACCTGGTACTTCAACC
GGTACCCCGGGGCCCGGTGTGACGTCGAGAGCGTCGACTATTGCTACTCGTTCTCCGAGGAACTGCAGCAGGAGTGGAAC
TGGAGCGAGAAGTACGCCACCCAGGGCGAGATCCTGCGTTACATCAACTGGGTCGCCGACAAACTCGACCTGAGATCCGG
CATCACCTTCAACACGAAGGTCACCTCCGCGGTGCTGGACGAGGACACCCTTCGCTGGACGGTGACGACGGACGCCGGCA
CGGTGCTGTCCGCCCGGTTCGCCATCATGGCGACCGGTCCGCTGTCGGCGGCGCTCACACCACAGTTCCCCGGCCTCGAC
ACCTTCGCCGGCGACATCTACCACACCGCTGACTGGCCCCACGAGGACGTCGACTTCACCGGCAAGCGGGTCGCCGTCAT
CGGCACCGGATCGTCGGGAATCCAGTCGATTCCGATCATCGCCGAACAGGCCGCCCAGCTCTACGTCTTCCAGCGGACTC
CGAATTACAGTGTGCCCGCGGGCAACCGACCACTGACGGCGGAGGACATCGCCACGGTCAAAGCCAACTACGACGAGCGC
CGACAGCTGTCCTGGCGCAGCGGCGGCGGCTCACCGCACGTCGCACACCCGAAACTGACGATGGAGGCCTCCCTCGAGGA
GCGCAGGGCGGCGTTCGAGCGGCGCTGGGAGCTCGGCGGGGTGCTGTTCTCGAAGACCTTCCGCGACCAGATGATCGACC
CACAGGCCAACGACGAGGCCCGCAAGTTCTACGAGGAGAAGATCCGGGCGGTCATCGACGATCCCGAGGTCGCCGACCTG
CTGATCCCGAAAGATCACCCGATCGGCACCAAACGAATCTGCACCGACACCAACTACTTCCAGACGTTCAACCGACCGAA
CGTCGAGTTGATCAGCGTCCGGAAGACACCGATCGAATCGGTCGACCCAGCCGGGATCAACACCTCGGACGCGCACTATG
AGCTCGACGTCATCGTGCTGGCAACGGGATTCGACGCGATGACCGGGGCGTTGGCGAAGATGGACATCACAGGCCGGGAC
GGCGAGAAGCTGGCCGACGACTGGCGTGACGGCCCGAGGACCTACCTCGGGCTGGGCGTCGACGGGTTTCCCAACCTGTT
CATCGTGTCGGGTCCTGGCGCGCCGGCGGTGCTGGCCAACATGGTGTTGCACGCCGAGGCGCACGTGAACTGGATCGCGG
ACTGCATCGACTATCTGGACAGCCACGGGTACGCCGCCATCGAAGCGACCCCGCAGGCGGTGGACGACTGGGGCGCCGAA
CTCTCGCGGCGGGCCGATGCGACGCTGTTCACGCAGGCGAACTCGTGGTACATGGGCGCCAATGTGCCCGGTAAACCACG
GGTGTTCATGCTCTTCATCGGGGGGTTCGGGGTCTACCTCGACATCTGCGCCGAGGTCGCTGACGCCGGGTACAAGGGCT
TCGAACTGCTGAAGATCGATTGA

Upstream 100 bases:

>100_bases
CGGCGATCATGGGCGCGGACTGTGCCCGACAGGAACGCGACGTCCGTTGACCGGGACGGACCCCTCCGCGCGCGGGCGGC
CCACGCCTAGCTTGATCGTC

Downstream 100 bases:

>100_bases
TGCCGCGCCTCCTCGACAAGGTGGTCGTGGTGACCGGGGCGGCCCGGGGGACCGGCCGGGTGCACTGCGAGCGGTTCGCC
GAGGAAGGCGCCGACGTCAT

Product: FAD dependent oxidoreductase

Products: NA

Alternate protein names: PAMO; Baeyer-Villiger monooxygenase; BVMO [H]

Number of amino acids: Translated: 540; Mature: 540

Protein sequence:

>540_residues
MDTSADQLPNQVDAVVVGAGFAGLYALHKLRSQGLTVRVFEAAPDVGGTWYFNRYPGARCDVESVDYCYSFSEELQQEWN
WSEKYATQGEILRYINWVADKLDLRSGITFNTKVTSAVLDEDTLRWTVTTDAGTVLSARFAIMATGPLSAALTPQFPGLD
TFAGDIYHTADWPHEDVDFTGKRVAVIGTGSSGIQSIPIIAEQAAQLYVFQRTPNYSVPAGNRPLTAEDIATVKANYDER
RQLSWRSGGGSPHVAHPKLTMEASLEERRAAFERRWELGGVLFSKTFRDQMIDPQANDEARKFYEEKIRAVIDDPEVADL
LIPKDHPIGTKRICTDTNYFQTFNRPNVELISVRKTPIESVDPAGINTSDAHYELDVIVLATGFDAMTGALAKMDITGRD
GEKLADDWRDGPRTYLGLGVDGFPNLFIVSGPGAPAVLANMVLHAEAHVNWIADCIDYLDSHGYAAIEATPQAVDDWGAE
LSRRADATLFTQANSWYMGANVPGKPRVFMLFIGGFGVYLDICAEVADAGYKGFELLKID

Sequences:

>Translated_540_residues
MDTSADQLPNQVDAVVVGAGFAGLYALHKLRSQGLTVRVFEAAPDVGGTWYFNRYPGARCDVESVDYCYSFSEELQQEWN
WSEKYATQGEILRYINWVADKLDLRSGITFNTKVTSAVLDEDTLRWTVTTDAGTVLSARFAIMATGPLSAALTPQFPGLD
TFAGDIYHTADWPHEDVDFTGKRVAVIGTGSSGIQSIPIIAEQAAQLYVFQRTPNYSVPAGNRPLTAEDIATVKANYDER
RQLSWRSGGGSPHVAHPKLTMEASLEERRAAFERRWELGGVLFSKTFRDQMIDPQANDEARKFYEEKIRAVIDDPEVADL
LIPKDHPIGTKRICTDTNYFQTFNRPNVELISVRKTPIESVDPAGINTSDAHYELDVIVLATGFDAMTGALAKMDITGRD
GEKLADDWRDGPRTYLGLGVDGFPNLFIVSGPGAPAVLANMVLHAEAHVNWIADCIDYLDSHGYAAIEATPQAVDDWGAE
LSRRADATLFTQANSWYMGANVPGKPRVFMLFIGGFGVYLDICAEVADAGYKGFELLKID
>Mature_540_residues
MDTSADQLPNQVDAVVVGAGFAGLYALHKLRSQGLTVRVFEAAPDVGGTWYFNRYPGARCDVESVDYCYSFSEELQQEWN
WSEKYATQGEILRYINWVADKLDLRSGITFNTKVTSAVLDEDTLRWTVTTDAGTVLSARFAIMATGPLSAALTPQFPGLD
TFAGDIYHTADWPHEDVDFTGKRVAVIGTGSSGIQSIPIIAEQAAQLYVFQRTPNYSVPAGNRPLTAEDIATVKANYDER
RQLSWRSGGGSPHVAHPKLTMEASLEERRAAFERRWELGGVLFSKTFRDQMIDPQANDEARKFYEEKIRAVIDDPEVADL
LIPKDHPIGTKRICTDTNYFQTFNRPNVELISVRKTPIESVDPAGINTSDAHYELDVIVLATGFDAMTGALAKMDITGRD
GEKLADDWRDGPRTYLGLGVDGFPNLFIVSGPGAPAVLANMVLHAEAHVNWIADCIDYLDSHGYAAIEATPQAVDDWGAE
LSRRADATLFTQANSWYMGANVPGKPRVFMLFIGGFGVYLDICAEVADAGYKGFELLKID

Specific function: Catalyzes a Baeyer-Villiger oxidation reaction, i.e., the insertion of an oxygen atom into a carbon-carbon bond adjacent to a carbonyl, which converts ketones to esters. Is most efficient with phenylacetone as substrate, leading to the formation of benzyl

COG id: COG2072

COG function: function code P; Predicted flavoprotein involved in K+ transport

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-binding monooxygenase family [H]

Homologues:

Organism=Homo sapiens, GI4503755, Length=212, Percent_Identity=31.1320754716981, Blast_Score=80, Evalue=7e-15,
Organism=Homo sapiens, GI4503757, Length=210, Percent_Identity=31.4285714285714, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI50541965, Length=211, Percent_Identity=28.9099526066351, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI50541961, Length=211, Percent_Identity=28.9099526066351, Blast_Score=72, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI25150462, Length=246, Percent_Identity=28.8617886178862, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25145785, Length=207, Percent_Identity=26.0869565217391, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI19922866, Length=216, Percent_Identity=28.2407407407407, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI19921694, Length=225, Percent_Identity=25.7777777777778, Blast_Score=70, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020946 [H]

Pfam domain/function: PF00743 FMO-like [H]

EC number: =1.14.13.92 [H]

Molecular weight: Translated: 59482; Mature: 59482

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTSADQLPNQVDAVVVGAGFAGLYALHKLRSQGLTVRVFEAAPDVGGTWYFNRYPGARC
CCCCHHHCCCCCCEEEEECCHHHHHHHHHHHHCCCEEEEEECCCCCCCEEEEECCCCCCC
DVESVDYCYSFSEELQQEWNWSEKYATQGEILRYINWVADKLDLRSGITFNTKVTSAVLD
CHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHHHCCCEECCCHHHHHCC
EDTLRWTVTTDAGTVLSARFAIMATGPLSAALTPQFPGLDTFAGDIYHTADWPHEDVDFT
CCCEEEEEECCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCC
GKRVAVIGTGSSGIQSIPIIAEQAAQLYVFQRTPNYSVPAGNRPLTAEDIATVKANYDER
CCEEEEEECCCCCCCCCCHHHHCCCEEEEEEECCCCCCCCCCCCCCHHHHHEEECCCCHH
RQLSWRSGGGSPHVAHPKLTMEASLEERRAAFERRWELGGVLFSKTFRDQMIDPQANDEA
HHEEECCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHH
RKFYEEKIRAVIDDPEVADLLIPKDHPIGTKRICTDTNYFQTFNRPNVELISVRKTPIES
HHHHHHHHHHHCCCCCCEEEECCCCCCCCCCEEECCCHHHHHCCCCCEEEEEEECCCCCC
VDPAGINTSDAHYELDVIVLATGFDAMTGALAKMDITGRDGEKLADDWRDGPRTYLGLGV
CCCCCCCCCCCCEEEEEEEEEECCHHHHCCCEEEEECCCCCHHHHHHHCCCCCEEEEECC
DGFPNLFIVSGPGAPAVLANMVLHAEAHVNWIADCIDYLDSHGYAAIEATPQAVDDWGAE
CCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHH
LSRRADATLFTQANSWYMGANVPGKPRVFMLFIGGFGVYLDICAEVADAGYKGFELLKID
HHHCCCCEEEEECCCEEECCCCCCCCEEEEEEECCHHHHHHHHHHHHHCCCCCEEEEEEC
>Mature Secondary Structure
MDTSADQLPNQVDAVVVGAGFAGLYALHKLRSQGLTVRVFEAAPDVGGTWYFNRYPGARC
CCCCHHHCCCCCCEEEEECCHHHHHHHHHHHHCCCEEEEEECCCCCCCEEEEECCCCCCC
DVESVDYCYSFSEELQQEWNWSEKYATQGEILRYINWVADKLDLRSGITFNTKVTSAVLD
CHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHHHCCCEECCCHHHHHCC
EDTLRWTVTTDAGTVLSARFAIMATGPLSAALTPQFPGLDTFAGDIYHTADWPHEDVDFT
CCCEEEEEECCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCC
GKRVAVIGTGSSGIQSIPIIAEQAAQLYVFQRTPNYSVPAGNRPLTAEDIATVKANYDER
CCEEEEEECCCCCCCCCCHHHHCCCEEEEEEECCCCCCCCCCCCCCHHHHHEEECCCCHH
RQLSWRSGGGSPHVAHPKLTMEASLEERRAAFERRWELGGVLFSKTFRDQMIDPQANDEA
HHEEECCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHH
RKFYEEKIRAVIDDPEVADLLIPKDHPIGTKRICTDTNYFQTFNRPNVELISVRKTPIES
HHHHHHHHHHHCCCCCCEEEECCCCCCCCCCEEECCCHHHHHCCCCCEEEEEEECCCCCC
VDPAGINTSDAHYELDVIVLATGFDAMTGALAKMDITGRDGEKLADDWRDGPRTYLGLGV
CCCCCCCCCCCCEEEEEEEEEECCHHHHCCCEEEEECCCCCHHHHHHHCCCCCEEEEECC
DGFPNLFIVSGPGAPAVLANMVLHAEAHVNWIADCIDYLDSHGYAAIEATPQAVDDWGAE
CCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHH
LSRRADATLFTQANSWYMGANVPGKPRVFMLFIGGFGVYLDICAEVADAGYKGFELLKID
HHHCCCCEEEEECCCEEECCCCCCCCEEEEEEECCHHHHHHHHHHHHHCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA