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The map label for this gene is mmpL4 [H]

Identifier: 119855384

GI number: 119855384

Start: 198707

End: 201544

Strand: Reverse

Name: mmpL4 [H]

Synonym: Mkms_6000

Alternate gene names: 119855384

Gene position: 201544-198707 (Counterclockwise)

Preceding gene: 119855385

Following gene: 119855383

Centisome position: 92.98

GC content: 61.21

Gene sequence:

>2838_bases
ATGAGTTCCCATCGCGCCAAGCGTCCGTTCATCGCGAGCACGGTCCGACTCCTGGCGGTTCCGATTGTCGTGTTCTGGGC
GTTGCTCGCCGTGTCGACGAACACCTTCATGCCGCAAGTTGAACGGGTCGCAGAAGAACTCGCTGGCCCGATGGTCCCGA
CGTACGCGCCGTCGCAGTCGGGGATGCTGCACATCGGTGAAAAGTTCCAGGAATCCGACTCCACCAGCTTGACCATGGTC
ATCTTGGAAGCCGACCGACCGTTGGAAGATCAAGACCACCGGTTCTACGACGACCTGGTGCAGCGGCTCAAGCAGGACAC
CGCTCACGTGCAATACGTCATGGATCTGTGGGGCAAACCGATCACGGCGGCCGGAGCTCAAAGTGTCGACGGCAAGGCCG
CCTACGTGCTGATACGTATTGCCGGTGACAGCGGCCAACTCAGGGCGAATCAATCGGTGGACGCCATCCGTCACATCGTC
AGCGAGCAGCCTCCGCCGGCGGGACTCAAGGCCTACGTCAGTGGCGCGGGACCACTGGCTTCGGACACGCTGACCATCGC
CAATGGCAGCCTGAACAACGTCACGATCGTCACGATCTTCCTGATCATCGGGATGCTGCTGCTGGTGTACCGCTCGGTGT
CCAGCGTATTCATGCCACTGGCCACCGTTCTCATCGAGATGTTGGTCGCCAAGGGGGTGATCGCCACCCTCGGTCACCTC
GGCTACATCGAGCTCTCATCCTTTGCGGTCAACATCGTCATTGCGCTGTCGCTGGGAGCCGGCACCGACTACGGCATCTT
CCTCATGGGTCGCTATCAGGAGGCCCGCCAAGCCGGCGAAAGCCGCGAAGACGCGTACTTCACCGCCTACAAGGGCGTCT
TGCCCGTCATCATCGGCTCCGGCCTAACCATCGCGGGCGCCGGTTTCTGTCTGAGTCTTGCGCGACTGAACTACTTCCAC
ACCATGGGGCCGGCGGTCGCTATCAGCATGCTGTTTACCATCGCCGCCGCCCTCACGCTCGGCCCGGCCATCCTGACCAT
CGGTAGCATTTTCGGGCTCTTTGACCCCAAGCGACTGGCAAATGCACACCTGTACCGGCGCATCGGGGCCAGCGTCGTGC
GCTGGCCAGTCCCGATTCTGGCCGCCAGCACCGCCGTCGTCATGCTGGGGGCGGTGTTCGTGCCCACCTATCGGGTGAGC
TATGACGATCGCACCTATCAGCCCGCTGACGCTCCAGCAAATCAGGGTTTCGCCGCCGCGGATCGGCACTTCCCGCCGAG
CAAGCTGTTCACTGAGATGCTGATGGTCGAGACCGACCACGACATGCGCAACTCCGCGGACTTCATCTCCCTGGACCGGG
TGGCTAAAGCGCTCATCCGCCTTCCCGGCATCGCGATGGTGCAAAGCGTCACCAGACCCCTGGGCCGGCCCTTGGAGCAC
GCCAGCATCCCCTATCTATTCACCACACAGGGAAGCGGGGCCGGCCAACAGCTGCCGTTCGCCCAGCAGCAGAACGCGAA
CACCGACGAGCAGGCGAAGATCCAGGCGCAGTCGGTGGAGACCTTGAAGCAGACGATCGCCCTGACCCAAAGTCTGGCCG
CGGAGCTGCACTCCACCGCCCTGACCATTGACAATCTGCACCAAGTCTCGGAAAACATGCGTGACCAGATCGCGAACCTC
GAGGACTTCTTCCGGCCGTTGAAGAACTACTTTTATTGGGAGCCGCACTGTTTCAATATCCCGATCTGTTGGGCCTTCCG
CTCCCTGTTCGATGGGCTCGACAACATCGACGCTCTGGAAGCCAATATCGCCGACGCCGCGATGTCCATCGAGGCGGTCG
ATCAGCTTCTCCCGCAGATGATCTCGCAGCTGCAAACGATGGCTGAGCACTCTCAAGCGCTGCTGGACATCCTGGTCAAC
TCCTACGGCCCGGCGAACCTGCAGTCCACCCAGACCGAGCAGACCTTCGAGGATCTGATCAACGTGGGCAATGACTTCGA
CACGTCGCGCAGTGACGACTTTTTCTATATACCCCGGGAAGCTTTCGACAACGAGGACGTCAAGACCGGCATCGAGCTGA
TGATGTCGCCCGATGGTAAGGCCGCGCGCTTCGTCATCACCCACGAAGGCAACGCCATGGGCCCCGAAGGCGTCGAACAC
GTCGAGGCGTTCCCTGACGCGGTGAAAATAGCGTTGAAGGAGACCTCACTGGCAGGTGCCAAGGTGTACATCGGCGGCGC
GGCATCCAACAACAAGGACATCAAAGAACTCGCCGCCTCGGATCTGCTCATCGTGGCGATCGCGGCCTTCGTCCTGATCT
TCTTGATCATGATGACCCTCACCCGAAGCCTGGTCGCGGCCATCGTCATTCCCGGCACGGTGGCCTTCTCATTTGCCGGT
GCGTTCGGTCTGTCGGTTCTGGTGTGGCAACACCTTATCGGCCTGCACCTGCATTGGCTCGTGTTACCCCTGACGTTCAT
CATCCTGGTCGCGGTCGGGTCGGACTACAACCTGCTGTTGATCGCCCGCGTCAAAGAGGAAGTCGGCGCCGGGTTACACA
CCGGTCTGATCCGCGCGCTCGGAAGTACCGGCGGGGTAGTGACCTCGGCGGGTCTGGTGTTCGCGTTCACCATGCTTTCG
ATGCTCATCAGTGACCTGAGGACTATCGGTCAGGTGGGTTCCACGATCTGCATCGGTCTGCTTCTCGACACCTTGATCGT
GCGTTCGTTCGTGGTGCCGTGTCTACTGCGGATTATGGGGCCGTGGTTCTGGTGGCCCACGCTGGTGCGGACTCGGCCGT
TACGTCAGGTGTCCGATTTCGGGGTGAAGCAAGGATGA

Upstream 100 bases:

>100_bases
GAGGTGAGGTCGGCTGCCGGATACTGGTCAACGGCGTTGTGCACGATGAACAATCGGCTACTCGTCAAGATGCCGATGTG
ACCTGCCGGGTGAAGTCTGC

Downstream 100 bases:

>100_bases
CGGCGTCATGGGCGGCATTGACGATCATTTCCCTGGCCGCCGTAGTGGTGTTCGCCGCATTCGGCGCGGTGTTTGTGATC
CGTCGGGTGCGCCGTCCCGC

Product: MMPL domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 945; Mature: 944

Protein sequence:

>945_residues
MSSHRAKRPFIASTVRLLAVPIVVFWALLAVSTNTFMPQVERVAEELAGPMVPTYAPSQSGMLHIGEKFQESDSTSLTMV
ILEADRPLEDQDHRFYDDLVQRLKQDTAHVQYVMDLWGKPITAAGAQSVDGKAAYVLIRIAGDSGQLRANQSVDAIRHIV
SEQPPPAGLKAYVSGAGPLASDTLTIANGSLNNVTIVTIFLIIGMLLLVYRSVSSVFMPLATVLIEMLVAKGVIATLGHL
GYIELSSFAVNIVIALSLGAGTDYGIFLMGRYQEARQAGESREDAYFTAYKGVLPVIIGSGLTIAGAGFCLSLARLNYFH
TMGPAVAISMLFTIAAALTLGPAILTIGSIFGLFDPKRLANAHLYRRIGASVVRWPVPILAASTAVVMLGAVFVPTYRVS
YDDRTYQPADAPANQGFAAADRHFPPSKLFTEMLMVETDHDMRNSADFISLDRVAKALIRLPGIAMVQSVTRPLGRPLEH
ASIPYLFTTQGSGAGQQLPFAQQQNANTDEQAKIQAQSVETLKQTIALTQSLAAELHSTALTIDNLHQVSENMRDQIANL
EDFFRPLKNYFYWEPHCFNIPICWAFRSLFDGLDNIDALEANIADAAMSIEAVDQLLPQMISQLQTMAEHSQALLDILVN
SYGPANLQSTQTEQTFEDLINVGNDFDTSRSDDFFYIPREAFDNEDVKTGIELMMSPDGKAARFVITHEGNAMGPEGVEH
VEAFPDAVKIALKETSLAGAKVYIGGAASNNKDIKELAASDLLIVAIAAFVLIFLIMMTLTRSLVAAIVIPGTVAFSFAG
AFGLSVLVWQHLIGLHLHWLVLPLTFIILVAVGSDYNLLLIARVKEEVGAGLHTGLIRALGSTGGVVTSAGLVFAFTMLS
MLISDLRTIGQVGSTICIGLLLDTLIVRSFVVPCLLRIMGPWFWWPTLVRTRPLRQVSDFGVKQG

Sequences:

>Translated_945_residues
MSSHRAKRPFIASTVRLLAVPIVVFWALLAVSTNTFMPQVERVAEELAGPMVPTYAPSQSGMLHIGEKFQESDSTSLTMV
ILEADRPLEDQDHRFYDDLVQRLKQDTAHVQYVMDLWGKPITAAGAQSVDGKAAYVLIRIAGDSGQLRANQSVDAIRHIV
SEQPPPAGLKAYVSGAGPLASDTLTIANGSLNNVTIVTIFLIIGMLLLVYRSVSSVFMPLATVLIEMLVAKGVIATLGHL
GYIELSSFAVNIVIALSLGAGTDYGIFLMGRYQEARQAGESREDAYFTAYKGVLPVIIGSGLTIAGAGFCLSLARLNYFH
TMGPAVAISMLFTIAAALTLGPAILTIGSIFGLFDPKRLANAHLYRRIGASVVRWPVPILAASTAVVMLGAVFVPTYRVS
YDDRTYQPADAPANQGFAAADRHFPPSKLFTEMLMVETDHDMRNSADFISLDRVAKALIRLPGIAMVQSVTRPLGRPLEH
ASIPYLFTTQGSGAGQQLPFAQQQNANTDEQAKIQAQSVETLKQTIALTQSLAAELHSTALTIDNLHQVSENMRDQIANL
EDFFRPLKNYFYWEPHCFNIPICWAFRSLFDGLDNIDALEANIADAAMSIEAVDQLLPQMISQLQTMAEHSQALLDILVN
SYGPANLQSTQTEQTFEDLINVGNDFDTSRSDDFFYIPREAFDNEDVKTGIELMMSPDGKAARFVITHEGNAMGPEGVEH
VEAFPDAVKIALKETSLAGAKVYIGGAASNNKDIKELAASDLLIVAIAAFVLIFLIMMTLTRSLVAAIVIPGTVAFSFAG
AFGLSVLVWQHLIGLHLHWLVLPLTFIILVAVGSDYNLLLIARVKEEVGAGLHTGLIRALGSTGGVVTSAGLVFAFTMLS
MLISDLRTIGQVGSTICIGLLLDTLIVRSFVVPCLLRIMGPWFWWPTLVRTRPLRQVSDFGVKQG
>Mature_944_residues
SSHRAKRPFIASTVRLLAVPIVVFWALLAVSTNTFMPQVERVAEELAGPMVPTYAPSQSGMLHIGEKFQESDSTSLTMVI
LEADRPLEDQDHRFYDDLVQRLKQDTAHVQYVMDLWGKPITAAGAQSVDGKAAYVLIRIAGDSGQLRANQSVDAIRHIVS
EQPPPAGLKAYVSGAGPLASDTLTIANGSLNNVTIVTIFLIIGMLLLVYRSVSSVFMPLATVLIEMLVAKGVIATLGHLG
YIELSSFAVNIVIALSLGAGTDYGIFLMGRYQEARQAGESREDAYFTAYKGVLPVIIGSGLTIAGAGFCLSLARLNYFHT
MGPAVAISMLFTIAAALTLGPAILTIGSIFGLFDPKRLANAHLYRRIGASVVRWPVPILAASTAVVMLGAVFVPTYRVSY
DDRTYQPADAPANQGFAAADRHFPPSKLFTEMLMVETDHDMRNSADFISLDRVAKALIRLPGIAMVQSVTRPLGRPLEHA
SIPYLFTTQGSGAGQQLPFAQQQNANTDEQAKIQAQSVETLKQTIALTQSLAAELHSTALTIDNLHQVSENMRDQIANLE
DFFRPLKNYFYWEPHCFNIPICWAFRSLFDGLDNIDALEANIADAAMSIEAVDQLLPQMISQLQTMAEHSQALLDILVNS
YGPANLQSTQTEQTFEDLINVGNDFDTSRSDDFFYIPREAFDNEDVKTGIELMMSPDGKAARFVITHEGNAMGPEGVEHV
EAFPDAVKIALKETSLAGAKVYIGGAASNNKDIKELAASDLLIVAIAAFVLIFLIMMTLTRSLVAAIVIPGTVAFSFAGA
FGLSVLVWQHLIGLHLHWLVLPLTFIILVAVGSDYNLLLIARVKEEVGAGLHTGLIRALGSTGGVVTSAGLVFAFTMLSM
LISDLRTIGQVGSTICIGLLLDTLIVRSFVVPCLLRIMGPWFWWPTLVRTRPLRQVSDFGVKQG

Specific function: Unknown

COG id: COG2409

COG function: function code R; Predicted drug exporters of the RND superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mmpL family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004707
- InterPro:   IPR004869 [H]

Pfam domain/function: PF03176 MMPL [H]

EC number: NA

Molecular weight: Translated: 102531; Mature: 102400

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSHRAKRPFIASTVRLLAVPIVVFWALLAVSTNTFMPQVERVAEELAGPMVPTYAPSQS
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCC
GMLHIGEKFQESDSTSLTMVILEADRPLEDQDHRFYDDLVQRLKQDTAHVQYVMDLWGKP
CCCHHHHHHCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
ITAAGAQSVDGKAAYVLIRIAGDSGQLRANQSVDAIRHIVSEQPPPAGLKAYVSGAGPLA
CCCCCCCCCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHCCCCCCCC
SDTLTIANGSLNNVTIVTIFLIIGMLLLVYRSVSSVFMPLATVLIEMLVAKGVIATLGHL
CCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GYIELSSFAVNIVIALSLGAGTDYGIFLMGRYQEARQAGESREDAYFTAYKGVLPVIIGS
CCEEHHHHHEEEEEEEEECCCCCCCEEEEECCHHHHHCCCCCCCHHHHHHHHHHHHHHCC
GLTIAGAGFCLSLARLNYFHTMGPAVAISMLFTIAAALTLGPAILTIGSIFGLFDPKRLA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
NAHLYRRIGASVVRWPVPILAASTAVVMLGAVFVPTYRVSYDDRTYQPADAPANQGFAAA
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCCCCC
DRHFPPSKLFTEMLMVETDHDMRNSADFISLDRVAKALIRLPGIAMVQSVTRPLGRPLEH
CCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHH
ASIPYLFTTQGSGAGQQLPFAQQQNANTDEQAKIQAQSVETLKQTIALTQSLAAELHSTA
CCCCEEEEECCCCCCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTIDNLHQVSENMRDQIANLEDFFRPLKNYFYWEPHCFNIPICWAFRSLFDGLDNIDALE
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHCEECCCCCCCCHHHHHHHHHHCCCCCCHHHH
ANIADAAMSIEAVDQLLPQMISQLQTMAEHSQALLDILVNSYGPANLQSTQTEQTFEDLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
NVGNDFDTSRSDDFFYIPREAFDNEDVKTGIELMMSPDGKAARFVITHEGNAMGPEGVEH
HCCCCCCCCCCCCEEECCHHHCCCCHHHHHHHEEECCCCCEEEEEEEECCCCCCCCHHHH
VEAFPDAVKIALKETSLAGAKVYIGGAASNNKDIKELAASDLLIVAIAAFVLIFLIMMTL
HHHCHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TRSLVAAIVIPGTVAFSFAGAFGLSVLVWQHLIGLHLHWLVLPLTFIILVAVGSDYNLLL
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
IARVKEEVGAGLHTGLIRALGSTGGVVTSAGLVFAFTMLSMLISDLRTIGQVGSTICIGL
EEEEHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLDTLIVRSFVVPCLLRIMGPWFWWPTLVRTRPLRQVSDFGVKQG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCC
>Mature Secondary Structure 
SSHRAKRPFIASTVRLLAVPIVVFWALLAVSTNTFMPQVERVAEELAGPMVPTYAPSQS
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCC
GMLHIGEKFQESDSTSLTMVILEADRPLEDQDHRFYDDLVQRLKQDTAHVQYVMDLWGKP
CCCHHHHHHCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
ITAAGAQSVDGKAAYVLIRIAGDSGQLRANQSVDAIRHIVSEQPPPAGLKAYVSGAGPLA
CCCCCCCCCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHCCCCCCCC
SDTLTIANGSLNNVTIVTIFLIIGMLLLVYRSVSSVFMPLATVLIEMLVAKGVIATLGHL
CCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GYIELSSFAVNIVIALSLGAGTDYGIFLMGRYQEARQAGESREDAYFTAYKGVLPVIIGS
CCEEHHHHHEEEEEEEEECCCCCCCEEEEECCHHHHHCCCCCCCHHHHHHHHHHHHHHCC
GLTIAGAGFCLSLARLNYFHTMGPAVAISMLFTIAAALTLGPAILTIGSIFGLFDPKRLA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
NAHLYRRIGASVVRWPVPILAASTAVVMLGAVFVPTYRVSYDDRTYQPADAPANQGFAAA
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCCCCC
DRHFPPSKLFTEMLMVETDHDMRNSADFISLDRVAKALIRLPGIAMVQSVTRPLGRPLEH
CCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHH
ASIPYLFTTQGSGAGQQLPFAQQQNANTDEQAKIQAQSVETLKQTIALTQSLAAELHSTA
CCCCEEEEECCCCCCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTIDNLHQVSENMRDQIANLEDFFRPLKNYFYWEPHCFNIPICWAFRSLFDGLDNIDALE
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHCEECCCCCCCCHHHHHHHHHHCCCCCCHHHH
ANIADAAMSIEAVDQLLPQMISQLQTMAEHSQALLDILVNSYGPANLQSTQTEQTFEDLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
NVGNDFDTSRSDDFFYIPREAFDNEDVKTGIELMMSPDGKAARFVITHEGNAMGPEGVEH
HCCCCCCCCCCCCEEECCHHHCCCCHHHHHHHEEECCCCCEEEEEEEECCCCCCCCHHHH
VEAFPDAVKIALKETSLAGAKVYIGGAASNNKDIKELAASDLLIVAIAAFVLIFLIMMTL
HHHCHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TRSLVAAIVIPGTVAFSFAGAFGLSVLVWQHLIGLHLHWLVLPLTFIILVAVGSDYNLLL
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
IARVKEEVGAGLHTGLIRALGSTGGVVTSAGLVFAFTMLSMLISDLRTIGQVGSTICIGL
EEEEHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLDTLIVRSFVVPCLLRIMGPWFWWPTLVRTRPLRQVSDFGVKQG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]