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The map label for this gene is iap [H]

Identifier: 119855075

GI number: 119855075

Start: 198238

End: 199008

Strand: Reverse

Name: iap [H]

Synonym: Mkms_5687

Alternate gene names: 119855075

Gene position: 199008-198238 (Counterclockwise)

Preceding gene: 119855085

Following gene: 119855073

Centisome position: 65.88

GC content: 64.2

Gene sequence:

>771_bases
ATGGAATCACACGCCCGGGGCAAGGGTGAAGCACCTGCCGGCGCTGACCGTTCCGACCCGGCGATCCGCATTGCGAGACT
CGCTCGACGGCTCCCCGCAGTTATCGCGACCGTTATCTTGCTTTTGCTCGCATGTGCACCGGTCGCGTCGGCCCAACCTG
CTGCCGGTCCCTGGGACCCCCTCCTTCCAAAGCTGCCGAGCGCAGGCGCTCCCGGTGATCCGGTCGCCATCGCGAACGCA
TCGCTTCAGGCCACGGCTTTGGCGACGCAGACGGCGATGAATATGGGTCGCAACTTCCTCAGCAGCCTGGGAATCGTCAG
TCCTGCCGCAGATCCGTCGACGAGCGTGCGCGGAAATCGCGTTAATGGTCCCCAAGCGATCGAGTACGTCATCCGCCGAG
CGGGAACACAAATCGGTGTCCCCTACTCCTGGGGTGGGGGAAGCCTCACAGGCCCAACCCGCGGCGTCGACCAGGGAGCG
GACACCGTCGGCTTTGACTGTTCAGGCCTTACGCGGTTCGCCTTCGCCGGCGTCGGAGTGCTGCTGCCGCGATGGTCCGG
CGACCAGTACGACGCCGGCCGAAAGGTTCCTCCCTCTCAGGCTAAACGCGGCGACCTGTTGTTCTGGGGGCCCGGCGGAA
GTCAACACGAAGCGATCTACTTGGGCGGAGGACAGATGATCGAGGCGCAACGAACTGGCGTTCCCATCAAAGTCTCACCA
GTGCGCCACGCTGGGATGACACCGTACGTCGTACGGATTATCGAGAGCTGA

Upstream 100 bases:

>100_bases
CTACGTAGTAGGTACGTATTTGTGCCGCGCTCACGTTCGCGATTCAGCCCGCTATTGGCGCGTGGGAGTAGCTCGCCGCG
CGGCGCACCGAGGAGAAGAC

Downstream 100 bases:

>100_bases
CCGAGATCGCCCAATCAGCAAGCGCGCCAAGCCGTTCACCTTCGCGCGTGACCGCATCACCCGACGAGACGGTAGCCAAC
GCGGACGGTGCGGAGGTAGC

Product: NLP/P60 protein

Products: NA

Alternate protein names: Invasion-associated protein [H]

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MESHARGKGEAPAGADRSDPAIRIARLARRLPAVIATVILLLLACAPVASAQPAAGPWDPLLPKLPSAGAPGDPVAIANA
SLQATALATQTAMNMGRNFLSSLGIVSPAADPSTSVRGNRVNGPQAIEYVIRRAGTQIGVPYSWGGGSLTGPTRGVDQGA
DTVGFDCSGLTRFAFAGVGVLLPRWSGDQYDAGRKVPPSQAKRGDLLFWGPGGSQHEAIYLGGGQMIEAQRTGVPIKVSP
VRHAGMTPYVVRIIES

Sequences:

>Translated_256_residues
MESHARGKGEAPAGADRSDPAIRIARLARRLPAVIATVILLLLACAPVASAQPAAGPWDPLLPKLPSAGAPGDPVAIANA
SLQATALATQTAMNMGRNFLSSLGIVSPAADPSTSVRGNRVNGPQAIEYVIRRAGTQIGVPYSWGGGSLTGPTRGVDQGA
DTVGFDCSGLTRFAFAGVGVLLPRWSGDQYDAGRKVPPSQAKRGDLLFWGPGGSQHEAIYLGGGQMIEAQRTGVPIKVSP
VRHAGMTPYVVRIIES
>Mature_256_residues
MESHARGKGEAPAGADRSDPAIRIARLARRLPAVIATVILLLLACAPVASAQPAAGPWDPLLPKLPSAGAPGDPVAIANA
SLQATALATQTAMNMGRNFLSSLGIVSPAADPSTSVRGNRVNGPQAIEYVIRRAGTQIGVPYSWGGGSLTGPTRGVDQGA
DTVGFDCSGLTRFAFAGVGVLLPRWSGDQYDAGRKVPPSQAKRGDLLFWGPGGSQHEAIYLGGGQMIEAQRTGVPIKVSP
VRHAGMTPYVVRIIES

Specific function: This major extracellular protein may be involved in the invasion of non-professional phagocytic cells by Listeria [H]

COG id: COG0791

COG function: function code M; Cell wall-associated hydrolases (invasion-associated proteins)

Gene ontology:

Cell location: Attached To The Membrane By A Lipid Anchor [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 LysM repeats [H]

Homologues:

Organism=Escherichia coli, GI1786421, Length=118, Percent_Identity=38.135593220339, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1787944, Length=184, Percent_Identity=27.7173913043478, Blast_Score=72, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000064
- InterPro:   IPR018392
- InterPro:   IPR002482
- InterPro:   IPR003646
- InterPro:   IPR013247 [H]

Pfam domain/function: PF01476 LysM; PF00877 NLPC_P60; PF08239 SH3_3 [H]

EC number: NA

Molecular weight: Translated: 26404; Mature: 26404

Theoretical pI: Translated: 10.24; Mature: 10.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESHARGKGEAPAGADRSDPAIRIARLARRLPAVIATVILLLLACAPVASAQPAAGPWDP
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
LLPKLPSAGAPGDPVAIANASLQATALATQTAMNMGRNFLSSLGIVSPAADPSTSVRGNR
CCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
VNGPQAIEYVIRRAGTQIGVPYSWGGGSLTGPTRGVDQGADTVGFDCSGLTRFAFAGVGV
CCCHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCHH
LLPRWSGDQYDAGRKVPPSQAKRGDLLFWGPGGSQHEAIYLGGGQMIEAQRTGVPIKVSP
EEECCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCEEEECCCEEEEHHHCCCCEEECC
VRHAGMTPYVVRIIES
CCCCCCCHHHEEEECC
>Mature Secondary Structure
MESHARGKGEAPAGADRSDPAIRIARLARRLPAVIATVILLLLACAPVASAQPAAGPWDP
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
LLPKLPSAGAPGDPVAIANASLQATALATQTAMNMGRNFLSSLGIVSPAADPSTSVRGNR
CCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
VNGPQAIEYVIRRAGTQIGVPYSWGGGSLTGPTRGVDQGADTVGFDCSGLTRFAFAGVGV
CCCHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCHH
LLPRWSGDQYDAGRKVPPSQAKRGDLLFWGPGGSQHEAIYLGGGQMIEAQRTGVPIKVSP
EEECCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCEEEECCCEEEEHHHCCCCEEECC
VRHAGMTPYVVRIIES
CCCCCCCHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1514809; 1459966 [H]