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The map label for this gene is nhaA [H]

Identifier: 119855073

GI number: 119855073

Start: 195973

End: 196632

Strand: Reverse

Name: nhaA [H]

Synonym: Mkms_5684

Alternate gene names: 119855073

Gene position: 196632-195973 (Counterclockwise)

Preceding gene: 119855075

Following gene: 119855069

Centisome position: 65.09

GC content: 61.36

Gene sequence:

>660_bases
ATGGCACCTCTCACACGCATTCTGCTGACCGTCTTCGCGGTCATCACCATGATCATCGGGGTTGGCGTCTATCTCTCGGC
ACAGGACAAGGACACACCCGGCTCCGCGCAAGCCCAGGGTGGAGACGTCGGTCAGCTGGTCCGGGAAAACAGTCGCCGCC
TCACCAACGTGCCAAATAGCGATGTCACCTTCGTCGAGTTCCTCGACTTCGAATGCGAAGCGTGCCGCGCGGCCTTCCCG
ATGGTCGAACAGCTGCGCGCCGAGTACGGGGACCGCGTCAACTTCGTCATCCGCTACTTCCCCATTCAGTCGCACTTCAA
TGCAGAGCGGGCGGCGCGTGCGGTCGAGGCGGCCGCTCAGCAGGACAAGTTCGAGCCCATGTACAAGAAGATGTATGAGA
CGCAAAGTGAGTGGGGCGAACAGCAAACTCCGGCGGACTCCCGATTCCGCGGGTTCGCCGCCGAACTTGGGCTGGACATG
GCGGCGTTCGACGCTGCCTACAACGACCCCGCCACACTCGATCGTGTCAATGTCGATGTGGCTGACGGTAAGGCCCTCGG
TGTCCAGGGCACACCGACCTTCTTCCTCGACGGAACCGAAGTGGAGTTCAGGAGCTACGACGACTTGAAGACCGCAGTCG
AACAGGCCTTGAACGGATAG

Upstream 100 bases:

>100_bases
GCGATGCTCAACCGCGGGCACGGTCCGAGTCGGAGCTGCGGTAGACGGCTGCTCCGGCGCATCATAGACGTTCGGTGAAA
CTCAAGAAGGACGCATTCGA

Downstream 100 bases:

>100_bases
CCGCGGTGATTGATGGCGGCCCCAGGGCGCAGCGGTTCGACACCTCGGCACGTGGATGGCGCCATCGGCGCTAACATGCC
GGCGCCGCCTCGTCGACGGC

Product: DSBA oxidoreductase

Products: NA

Alternate protein names: Sodium/proton antiporter nhaA [H]

Number of amino acids: Translated: 219; Mature: 218

Protein sequence:

>219_residues
MAPLTRILLTVFAVITMIIGVGVYLSAQDKDTPGSAQAQGGDVGQLVRENSRRLTNVPNSDVTFVEFLDFECEACRAAFP
MVEQLRAEYGDRVNFVIRYFPIQSHFNAERAARAVEAAAQQDKFEPMYKKMYETQSEWGEQQTPADSRFRGFAAELGLDM
AAFDAAYNDPATLDRVNVDVADGKALGVQGTPTFFLDGTEVEFRSYDDLKTAVEQALNG

Sequences:

>Translated_219_residues
MAPLTRILLTVFAVITMIIGVGVYLSAQDKDTPGSAQAQGGDVGQLVRENSRRLTNVPNSDVTFVEFLDFECEACRAAFP
MVEQLRAEYGDRVNFVIRYFPIQSHFNAERAARAVEAAAQQDKFEPMYKKMYETQSEWGEQQTPADSRFRGFAAELGLDM
AAFDAAYNDPATLDRVNVDVADGKALGVQGTPTFFLDGTEVEFRSYDDLKTAVEQALNG
>Mature_218_residues
APLTRILLTVFAVITMIIGVGVYLSAQDKDTPGSAQAQGGDVGQLVRENSRRLTNVPNSDVTFVEFLDFECEACRAAFPM
VEQLRAEYGDRVNFVIRYFPIQSHFNAERAARAVEAAAQQDKFEPMYKKMYETQSEWGEQQTPADSRFRGFAAELGLDMA
AFDAAYNDPATLDRVNVDVADGKALGVQGTPTFFLDGTEVEFRSYDDLKTAVEQALNG

Specific function: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons [H]

COG id: COG1651

COG function: function code O; Protein-disulfide isomerase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001853
- InterPro:   IPR023171
- InterPro:   IPR004670
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01323 DSBA; PF06965 Na_H_antiport_1 [H]

EC number: NA

Molecular weight: Translated: 24232; Mature: 24101

Theoretical pI: Translated: 4.25; Mature: 4.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPLTRILLTVFAVITMIIGVGVYLSAQDKDTPGSAQAQGGDVGQLVRENSRRLTNVPNS
CCHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCHHHHHHHHCCHHHCCCCCC
DVTFVEFLDFECEACRAAFPMVEQLRAEYGDRVNFVIRYFPIQSHFNAERAARAVEAAAQ
CCEEEHHHCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCHHHCCHHHHHHHHHHHHH
QDKFEPMYKKMYETQSEWGEQQTPADSRFRGFAAELGLDMAAFDAAYNDPATLDRVNVDV
HHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHCCCCCCCHHEEEEEE
ADGKALGVQGTPTFFLDGTEVEFRSYDDLKTAVEQALNG
CCCCEECCCCCCEEEECCCEEECCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
APLTRILLTVFAVITMIIGVGVYLSAQDKDTPGSAQAQGGDVGQLVRENSRRLTNVPNS
CHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCHHHHHHHHCCHHHCCCCCC
DVTFVEFLDFECEACRAAFPMVEQLRAEYGDRVNFVIRYFPIQSHFNAERAARAVEAAAQ
CCEEEHHHCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCHHHCCHHHHHHHHHHHHH
QDKFEPMYKKMYETQSEWGEQQTPADSRFRGFAAELGLDMAAFDAAYNDPATLDRVNVDV
HHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHCCCCCCCHHEEEEEE
ADGKALGVQGTPTFFLDGTEVEFRSYDDLKTAVEQALNG
CCCCEECCCCCCEEEECCCEEECCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA