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The map label for this gene is insK [C]

Identifier: 119855043

GI number: 119855043

Start: 163222

End: 164136

Strand: Reverse

Name: insK [C]

Synonym: Mkms_5653

Alternate gene names: 119855043

Gene position: 164136-163222 (Counterclockwise)

Preceding gene: 119855044

Following gene: 119854998

Centisome position: 54.33

GC content: 66.01

Gene sequence:

>915_bases
GTGCTCACCGAGCACGCCGTGCCGATCGCCCCGCGGACATTTCATGCCTGGGCGGTGCGGGCGCCCTCGAAACGGGCCCT
GTGGGACGCCACGATCACCGAGATCCTAGCCGGCTACTACGAGCCTGATGAGCACGGACGCCGCAGGCCCGAGTCGCTGT
ACGGGTCGCTGAAGATGTGGGCCCATCTGCAGCGTGAGGGCATCCCGGTGGCCAAGTCCACCGTGGAACGCCTGATGCGC
AAGAACGGCTGGCAAGGCGTGCGCCGCCAGAAGAGGGTCCGCACCACGATCCCCGACCCGGAGGCGGTGCGACCGCCGGA
CCTGGTGGACCGCCAATTCGGGGTGGCCGCACCCAACGTGCTGCTCGTGGCCGACTTCACCTACGTCAAGCTCGTCACCG
GCGTGTTCGTCTACGTCGCGTTCGTCATCGACGCCTACGCCGGGTCGATCGTGGGCTGGGAAGCCTCGGCGTCCAAGCAC
ACCCGCTTCGTCGAATCCGCGCTGCGTCAGGCCGCTGCACTGCGTGCCCGCCAAGGCCATCCCGTCGACGGCGCAATCCA
TCACAGCGACGCCGGCTCGCAGTACACGAGTGTGAGATTTGGTGAGACACTGAGCCTTTCGGGAATTCGCCCGTCCGTGG
GCAGTGTTGGGGATGCCTTCGACAACGCGCTGGCTGAGACGACCATCGGCCTGTACAAGAACGAATGTGTCCGGGCGGAT
TCCCCGTTTCGCCGCGGCCCACTGAACACCGTGGGCGACGTCGAATACATCACCGCCGACTACGTCGCCTGGTACAACCA
GCAGCGCCTGATGCACCGACTCGGACGCATTCCGCCGGCCGAAGCCGAAGCCCGCTACTATTCCCAACTCGTGACCGGTA
GACCGGCCGGATCACAGAAACCTGAGGGTGCATGA

Upstream 100 bases:

>100_bases
TCGTGCGGGAGAGCGACCCGCGCAACCGCCGCTGACCGCTACGGTCTGCGAGTTCATCGCCGCCCACCGGGACCGTTTCG
GGGTCGCTCCGATCTGCCGC

Downstream 100 bases:

>100_bases
AACCCGGGACGGTTCAAGGTGCCGGCACACCTCAGCCAGTTCCTGGCCGGCACCGAGGAGCTTGTTGCCCTCGGCGAGCT
TGCGGATGATCTGGTCCGGG

Product: integrase catalytic subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MLTEHAVPIAPRTFHAWAVRAPSKRALWDATITEILAGYYEPDEHGRRRPESLYGSLKMWAHLQREGIPVAKSTVERLMR
KNGWQGVRRQKRVRTTIPDPEAVRPPDLVDRQFGVAAPNVLLVADFTYVKLVTGVFVYVAFVIDAYAGSIVGWEASASKH
TRFVESALRQAAALRARQGHPVDGAIHHSDAGSQYTSVRFGETLSLSGIRPSVGSVGDAFDNALAETTIGLYKNECVRAD
SPFRRGPLNTVGDVEYITADYVAWYNQQRLMHRLGRIPPAEAEARYYSQLVTGRPAGSQKPEGA

Sequences:

>Translated_304_residues
MLTEHAVPIAPRTFHAWAVRAPSKRALWDATITEILAGYYEPDEHGRRRPESLYGSLKMWAHLQREGIPVAKSTVERLMR
KNGWQGVRRQKRVRTTIPDPEAVRPPDLVDRQFGVAAPNVLLVADFTYVKLVTGVFVYVAFVIDAYAGSIVGWEASASKH
TRFVESALRQAAALRARQGHPVDGAIHHSDAGSQYTSVRFGETLSLSGIRPSVGSVGDAFDNALAETTIGLYKNECVRAD
SPFRRGPLNTVGDVEYITADYVAWYNQQRLMHRLGRIPPAEAEARYYSQLVTGRPAGSQKPEGA
>Mature_304_residues
MLTEHAVPIAPRTFHAWAVRAPSKRALWDATITEILAGYYEPDEHGRRRPESLYGSLKMWAHLQREGIPVAKSTVERLMR
KNGWQGVRRQKRVRTTIPDPEAVRPPDLVDRQFGVAAPNVLLVADFTYVKLVTGVFVYVAFVIDAYAGSIVGWEASASKH
TRFVESALRQAAALRARQGHPVDGAIHHSDAGSQYTSVRFGETLSLSGIRPSVGSVGDAFDNALAETTIGLYKNECVRAD
SPFRRGPLNTVGDVEYITADYVAWYNQQRLMHRLGRIPPAEAEARYYSQLVTGRPAGSQKPEGA

Specific function: Involved in the transposition of the insertion sequence [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=263, Percent_Identity=40.3041825095057, Blast_Score=162, Evalue=4e-40,
Organism=Escherichia coli, GI1789981, Length=287, Percent_Identity=27.5261324041812, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1788405, Length=219, Percent_Identity=27.3972602739726, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1787263, Length=219, Percent_Identity=27.3972602739726, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1786753, Length=219, Percent_Identity=27.3972602739726, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1786570, Length=219, Percent_Identity=27.3972602739726, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1786490, Length=219, Percent_Identity=27.3972602739726, Blast_Score=79, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 33667; Mature: 33667

Theoretical pI: Translated: 9.79; Mature: 9.79

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTEHAVPIAPRTFHAWAVRAPSKRALWDATITEILAGYYEPDEHGRRRPESLYGSLKMW
CCCCCCCCCCCCCCHHEEECCCCCHHHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHH
AHLQREGIPVAKSTVERLMRKNGWQGVRRQKRVRTTIPDPEAVRPPDLVDRQFGVAAPNV
HHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCCCCE
LLVADFTYVKLVTGVFVYVAFVIDAYAGSIVGWEASASKHTRFVESALRQAAALRARQGH
EEEECHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCHHHHHHHHHHHHHHHHHHHHCCCC
PVDGAIHHSDAGSQYTSVRFGETLSLSGIRPSVGSVGDAFDNALAETTIGLYKNECVRAD
CCCCEEECCCCCCCEEEEECCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
SPFRRGPLNTVGDVEYITADYVAWYNQQRLMHRLGRIPPAEAEARYYSQLVTGRPAGSQK
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCC
PEGA
CCCC
>Mature Secondary Structure
MLTEHAVPIAPRTFHAWAVRAPSKRALWDATITEILAGYYEPDEHGRRRPESLYGSLKMW
CCCCCCCCCCCCCCHHEEECCCCCHHHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHH
AHLQREGIPVAKSTVERLMRKNGWQGVRRQKRVRTTIPDPEAVRPPDLVDRQFGVAAPNV
HHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCCCCE
LLVADFTYVKLVTGVFVYVAFVIDAYAGSIVGWEASASKHTRFVESALRQAAALRARQGH
EEEECHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCHHHHHHHHHHHHHHHHHHHHCCCC
PVDGAIHHSDAGSQYTSVRFGETLSLSGIRPSVGSVGDAFDNALAETTIGLYKNECVRAD
CCCCEEECCCCCCCEEEEECCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
SPFRRGPLNTVGDVEYITADYVAWYNQQRLMHRLGRIPPAEAEARYYSQLVTGRPAGSQK
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCC
PEGA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]