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The map label for this gene is menC [H]

Identifier: 119776594

GI number: 119776594

Start: 4091747

End: 4092850

Strand: Direct

Name: menC [H]

Synonym: Sama_3462

Alternate gene names: 119776594

Gene position: 4091747-4092850 (Clockwise)

Preceding gene: 119776593

Following gene: 119776595

Centisome position: 95.02

GC content: 58.79

Gene sequence:

>1104_bases
ATGTCTGACTCTTCTTTTGCCCTCTATCCCTATCGCATCGCCCTCAGCCGCCCGCTGCCCGTGGGTAAGCAGCGTATTAT
GCATCGCAGCGGCTTGGTGATAGAGGTACGCACCGGCGAGCGGAGCGTCTTCGCCGAAATAGCGCCCTTAAGCGGCCCGG
ATATGGATGGTGCCCCTATCCTTGGCTTCAGCTCCGAGTCGCTGGACGAATGCATTCAGACACTAAAAAGCAGTCTTGCA
GGCATTAGCCCGGCGACCGAAGCCGAGTGGGGAGCGAGGCTTGAGACTTTGGCCGATTCCGCTCCGGAAGCGTCAGTCGC
CTGGGGGCTGGGTATACTGGCCGCTCAGCTCAATGAGCAGCTCTGTGTGCTGTCACCTGATAGTGCCCAGCAGCCGGATG
ATAGTGCTCACCCAATGCTGGGCATCCCACTCATTTATCTTGCCCAGGACGAGCCACTGGAGAGCATACGAAAGCGCGTT
AAAGCGCTGCCAGATCACACCCGATTCGTAAAGGTGAAGGTGGGCCAAACCTCCATGGAGACCGAGCTGAACCTCATCCA
TGCGATTCTTGCAGAGCGGCCACAACTGAAGCTGCGTCTCGATGCCAATCAGGGCTTTGAGTTGGAAGATGCCATTGATT
TTTGTGCATGCCTGCCCAGGGGCGCCATCGATTATATCGAAGAGCCCTGTCGTAATCCGGCCGACAATCCAGCACTCTTC
CGGGCTGTTGGCATCAGCTATGCCCTGGATGAGTCTCTCATCCTGTCAGACTTTCACTTCCCGGATGATCCCCAGTCTCA
GGGGCTCAGGGCATTGGTGTTAAAGCCCATGCTGCTCGGCTCGCCCGCCCGGGTGCAGGCGTTTATTGAGGAAGCCCATT
CGCGGGGCATTCGCTGTGTTATCAGCTCGGCACTGGAGTCATCTCTGGGCATAGCCGCGCTGGCGGCCTTTGCCAAACAG
GTCACCCCGGACGAAGCGCCGGGGCTAGATACCCTGTTTCCCTTTGAGGCCGACTGCATCGTCTCACAAGGCCAAAAGCG
TTGCCTCACCCCAGACGCCCCGGGGCCTGTGCTTGGCTGTGAACTCGGAGCCTCGCTGCTGTGA

Upstream 100 bases:

>100_bases
ATTGAAGGCGCCGGCCACAATTGTCATGCCGAGCAGCCGAGCCTGTTTGCACGCAGTCTGCTTCAGGGCATATTCCATCA
ATCCAGCGCGGATCAATCGC

Downstream 100 bases:

>100_bases
GCCCTCAGCGTTCAGTCAGGCCTCAACTATCCATCTCGCCCCTGCAGCAAGCATCGGCCACCTGGCCCGACGCCCATGCA
CTGATAACGCCGGAATTCAC

Product: O-succinylbenzoate synthase

Products: NA

Alternate protein names: OSB synthase; OSBS; 4-(2'-carboxyphenyl)-4-oxybutyric acid synthase; o-succinylbenzoic acid synthase [H]

Number of amino acids: Translated: 367; Mature: 366

Protein sequence:

>367_residues
MSDSSFALYPYRIALSRPLPVGKQRIMHRSGLVIEVRTGERSVFAEIAPLSGPDMDGAPILGFSSESLDECIQTLKSSLA
GISPATEAEWGARLETLADSAPEASVAWGLGILAAQLNEQLCVLSPDSAQQPDDSAHPMLGIPLIYLAQDEPLESIRKRV
KALPDHTRFVKVKVGQTSMETELNLIHAILAERPQLKLRLDANQGFELEDAIDFCACLPRGAIDYIEEPCRNPADNPALF
RAVGISYALDESLILSDFHFPDDPQSQGLRALVLKPMLLGSPARVQAFIEEAHSRGIRCVISSALESSLGIAALAAFAKQ
VTPDEAPGLDTLFPFEADCIVSQGQKRCLTPDAPGPVLGCELGASLL

Sequences:

>Translated_367_residues
MSDSSFALYPYRIALSRPLPVGKQRIMHRSGLVIEVRTGERSVFAEIAPLSGPDMDGAPILGFSSESLDECIQTLKSSLA
GISPATEAEWGARLETLADSAPEASVAWGLGILAAQLNEQLCVLSPDSAQQPDDSAHPMLGIPLIYLAQDEPLESIRKRV
KALPDHTRFVKVKVGQTSMETELNLIHAILAERPQLKLRLDANQGFELEDAIDFCACLPRGAIDYIEEPCRNPADNPALF
RAVGISYALDESLILSDFHFPDDPQSQGLRALVLKPMLLGSPARVQAFIEEAHSRGIRCVISSALESSLGIAALAAFAKQ
VTPDEAPGLDTLFPFEADCIVSQGQKRCLTPDAPGPVLGCELGASLL
>Mature_366_residues
SDSSFALYPYRIALSRPLPVGKQRIMHRSGLVIEVRTGERSVFAEIAPLSGPDMDGAPILGFSSESLDECIQTLKSSLAG
ISPATEAEWGARLETLADSAPEASVAWGLGILAAQLNEQLCVLSPDSAQQPDDSAHPMLGIPLIYLAQDEPLESIRKRVK
ALPDHTRFVKVKVGQTSMETELNLIHAILAERPQLKLRLDANQGFELEDAIDFCACLPRGAIDYIEEPCRNPADNPALFR
AVGISYALDESLILSDFHFPDDPQSQGLRALVLKPMLLGSPARVQAFIEEAHSRGIRCVISSALESSLGIAALAAFAKQV
TPDEAPGLDTLFPFEADCIVSQGQKRCLTPDAPGPVLGCELGASLL

Specific function: Converts SHCHC to OSB [H]

COG id: COG1441

COG function: function code H; O-succinylbenzoate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788596, Length=336, Percent_Identity=32.4404761904762, Blast_Score=126, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013342
- InterPro:   IPR010196 [H]

Pfam domain/function: PF01188 MR_MLE [H]

EC number: =4.2.1.113 [H]

Molecular weight: Translated: 39448; Mature: 39316

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: PS00909 MR_MLE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDSSFALYPYRIALSRPLPVGKQRIMHRSGLVIEVRTGERSVFAEIAPLSGPDMDGAPI
CCCCCEEEEEEEEEECCCCCHHHHHHHHHCCCEEEEECCCCEEHEEECCCCCCCCCCCEE
LGFSSESLDECIQTLKSSLAGISPATEAEWGARLETLADSAPEASVAWGLGILAAQLNEQ
ECCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCC
LCVLSPDSAQQPDDSAHPMLGIPLIYLAQDEPLESIRKRVKALPDHTRFVKVKVGQTSME
EEEECCCCCCCCCCCCCCEECCCEEEEECCCCHHHHHHHHHHCCCCCEEEEEEECCCCHH
TELNLIHAILAERPQLKLRLDANQGFELEDAIDFCACLPRGAIDYIEEPCRNPADNPALF
HHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHH
RAVGISYALDESLILSDFHFPDDPQSQGLRALVLKPMLLGSPARVQAFIEEAHSRGIRCV
HHHCCHHHHCCHHEEECCCCCCCCHHCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHH
ISSALESSLGIAALAAFAKQVTPDEAPGLDTLFPFEADCIVSQGQKRCLTPDAPGPVLGC
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCEEEC
ELGASLL
CCCCCCC
>Mature Secondary Structure 
SDSSFALYPYRIALSRPLPVGKQRIMHRSGLVIEVRTGERSVFAEIAPLSGPDMDGAPI
CCCCEEEEEEEEEECCCCCHHHHHHHHHCCCEEEEECCCCEEHEEECCCCCCCCCCCEE
LGFSSESLDECIQTLKSSLAGISPATEAEWGARLETLADSAPEASVAWGLGILAAQLNEQ
ECCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCC
LCVLSPDSAQQPDDSAHPMLGIPLIYLAQDEPLESIRKRVKALPDHTRFVKVKVGQTSME
EEEECCCCCCCCCCCCCCEECCCEEEEECCCCHHHHHHHHHHCCCCCEEEEEEECCCCHH
TELNLIHAILAERPQLKLRLDANQGFELEDAIDFCACLPRGAIDYIEEPCRNPADNPALF
HHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHH
RAVGISYALDESLILSDFHFPDDPQSQGLRALVLKPMLLGSPARVQAFIEEAHSRGIRCV
HHHCCHHHHCCHHEEECCCCCCCCHHCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHH
ISSALESSLGIAALAAFAKQVTPDEAPGLDTLFPFEADCIVSQGQKRCLTPDAPGPVLGC
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCEEEC
ELGASLL
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA