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The map label for this gene is ykoW [H]

Identifier: 119776230

GI number: 119776230

Start: 3671396

End: 3673312

Strand: Direct

Name: ykoW [H]

Synonym: Sama_3098

Alternate gene names: 119776230

Gene position: 3671396-3673312 (Clockwise)

Preceding gene: 119776229

Following gene: 119776235

Centisome position: 85.26

GC content: 53.31

Gene sequence:

>1917_bases
ATGACTTCAACACCATCAGGGATAAACACACTGCCAATGCCACAGATAAATACCAAAACCATCAGTGTGCCCGATGCCAT
GCTGTGCGGCTGGCAGGAGATTGTTGATTTGGTGGCTGATATCACCGAATGCCCTTCCGCGCTTATCATGCGTATCCATG
AAGACGACATTGAGGTATTCGCCAGCAGCCGCTCGGCAGGCAATCCCTATGTTCCCCACGCCCGGGACGCATTGGGTCAC
GGCCTTTATTGCGAAACCGTGATCCGTGAGCGGCAGCAACTGGAGGTGCCCAACGCCCTCAAAGACCCCGAATGGGCCAA
TAACCCGGATATCAAACTGGGGATGATTTGCTACTGTGGCCTGCCTATCTTCTGGCCCGATAACACCCCCTTCGGCACCA
TCTGCATCCTGGACAACAAAGAAAGACACTTCAACGACAGGGTTCACGCTCTGCTGGGGCGCTTCCAATCTGCCCTGGAA
GGACATTTGCAGATCCTTTACCACAAGTCCGAGTTGAAAGTGCTTAATGAGGAGCTGGAGCATAAGGTGCAGGAGCGCAC
CCAGCGGCTTGCCGAGCTAAGCGCCCGATTGCTCAAAGAGATTGAACAGCGCACCGCCGCCGAAGGACATTTGGAGTTTC
ACCGTACCTTTGACCCCTTAACCCATTTGCCCAATCGTGCAACCCTCACCGAAAGGCTGCAAACGTTGCTGCCGAAACTG
AAAAAAGATGAACACCTGACACTTATCTACTTTGGGCTGCGCAATTTCAAATCGGTCAACGACAGCTACGGCTACCTCAC
CGGCGACTCAATTCTGGTGAGTCTGAGTCAACGACTGAGCCTTAAGCTGCCCGACAACTGGCTGCTGGCACGTATCGCAG
GGTCGGAGTTTGTTCTGGCAGCACTGCACAACGCCAGCACAGAGATGACAGAGCAGGTCATTGCACGGGTACTGAGCGAC
TGCTCAGTACCTTTCACCGTGAACACCAACAGCATTACGGTCCAAACCAACCTGGGTGTGGCCATTGCGCCGGTGGACGC
CACCGACTCGGTCAGCCTGCTGCAACGCGCCAGTGCTGCCATGAGCATTGCCAAAAAAGAAGGCGCTGTGGTGTCTTTTT
TCGGTCAGGAAACCCAAAAAGCGGCCCACGAGCGATTGCTGCTGGAGTCACATCTGCTGGATGCGCTGCATCAGGGCGAA
CTCGCGGTGTATTTTCAGCCTCTGGTGTCCGTTCGGGATAAGAAGCGCCTGGTTGGCGCCGAAGCACTGCTGCGCTGGCA
CAGCCCTGAACTGGGGAATGTTGGCCCGGACCGCTTTATTCCACTGGCCGAAAGTAATGGGCAAATTATTGAAATAGGTA
ACTTTGTTCTGCACGAGGCGATGAAACATGCCGCCCACTGGTGCAAGCGGAGCAATAATCCCTTCAAGATAGCCATCAAT
ATTTCACCGCTGCAGTTTCGTGAGCGACAGTTTGTCGAGCATATCGAAGATCTGCTCGATTTGTATGAATTGCCCCCCGG
CACGTTGGAGCTTGAAATCACTGAAGGCATTTTGCTGCAGGATGAACACCATGCCAGGGCAAGTCTGGCGCGACTGCGTC
ATCTGGGGGTGCAGATATCTCTGGATGACTTTGGCACCGGCTATTCATCACTGAGCTATCTGCAAAAGTATGCCTTCGAT
ACTCTGAAAATCGATCGCAGCTTTATCAGTAATCTTGAGTTCAACGAACAAAATCGTGAGCTGACCCGGGCCATTATTGC
CATGGCGCACAAGCTGAAGCTAAACGTGGTTGCTGAAGGGGTTGAGAATGCCTTTCAGGAGGCCTTTATCCAGGCCGAGG
AATGTGATTTTGCCCAGGGCTATCTGTATGGTAAGGCCATACCCGCAGAGAAGTTTGCGGAAAAGTTCACCCATTAA

Upstream 100 bases:

>100_bases
GCAGTCCTTTCACCTGCAACGCCTTTGGGGTAACGCGTTACTGCAACCGCTGTGGGTGAACTACACTCAATGAGACTGGC
GCGGGCACGCCCCGCGATAC

Downstream 100 bases:

>100_bases
TGTCGCAGTGTTCCCCCGTTACAGTCCCTTCCAGGCCCGGGTCATGTGCCTGCGTCCCATAGGGCCTGGGTAACTCTCGA
CCCTGAACCCTGCCGCTTTC

Product: GGDEF family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 638; Mature: 637

Protein sequence:

>638_residues
MTSTPSGINTLPMPQINTKTISVPDAMLCGWQEIVDLVADITECPSALIMRIHEDDIEVFASSRSAGNPYVPHARDALGH
GLYCETVIRERQQLEVPNALKDPEWANNPDIKLGMICYCGLPIFWPDNTPFGTICILDNKERHFNDRVHALLGRFQSALE
GHLQILYHKSELKVLNEELEHKVQERTQRLAELSARLLKEIEQRTAAEGHLEFHRTFDPLTHLPNRATLTERLQTLLPKL
KKDEHLTLIYFGLRNFKSVNDSYGYLTGDSILVSLSQRLSLKLPDNWLLARIAGSEFVLAALHNASTEMTEQVIARVLSD
CSVPFTVNTNSITVQTNLGVAIAPVDATDSVSLLQRASAAMSIAKKEGAVVSFFGQETQKAAHERLLLESHLLDALHQGE
LAVYFQPLVSVRDKKRLVGAEALLRWHSPELGNVGPDRFIPLAESNGQIIEIGNFVLHEAMKHAAHWCKRSNNPFKIAIN
ISPLQFRERQFVEHIEDLLDLYELPPGTLELEITEGILLQDEHHARASLARLRHLGVQISLDDFGTGYSSLSYLQKYAFD
TLKIDRSFISNLEFNEQNRELTRAIIAMAHKLKLNVVAEGVENAFQEAFIQAEECDFAQGYLYGKAIPAEKFAEKFTH

Sequences:

>Translated_638_residues
MTSTPSGINTLPMPQINTKTISVPDAMLCGWQEIVDLVADITECPSALIMRIHEDDIEVFASSRSAGNPYVPHARDALGH
GLYCETVIRERQQLEVPNALKDPEWANNPDIKLGMICYCGLPIFWPDNTPFGTICILDNKERHFNDRVHALLGRFQSALE
GHLQILYHKSELKVLNEELEHKVQERTQRLAELSARLLKEIEQRTAAEGHLEFHRTFDPLTHLPNRATLTERLQTLLPKL
KKDEHLTLIYFGLRNFKSVNDSYGYLTGDSILVSLSQRLSLKLPDNWLLARIAGSEFVLAALHNASTEMTEQVIARVLSD
CSVPFTVNTNSITVQTNLGVAIAPVDATDSVSLLQRASAAMSIAKKEGAVVSFFGQETQKAAHERLLLESHLLDALHQGE
LAVYFQPLVSVRDKKRLVGAEALLRWHSPELGNVGPDRFIPLAESNGQIIEIGNFVLHEAMKHAAHWCKRSNNPFKIAIN
ISPLQFRERQFVEHIEDLLDLYELPPGTLELEITEGILLQDEHHARASLARLRHLGVQISLDDFGTGYSSLSYLQKYAFD
TLKIDRSFISNLEFNEQNRELTRAIIAMAHKLKLNVVAEGVENAFQEAFIQAEECDFAQGYLYGKAIPAEKFAEKFTH
>Mature_637_residues
TSTPSGINTLPMPQINTKTISVPDAMLCGWQEIVDLVADITECPSALIMRIHEDDIEVFASSRSAGNPYVPHARDALGHG
LYCETVIRERQQLEVPNALKDPEWANNPDIKLGMICYCGLPIFWPDNTPFGTICILDNKERHFNDRVHALLGRFQSALEG
HLQILYHKSELKVLNEELEHKVQERTQRLAELSARLLKEIEQRTAAEGHLEFHRTFDPLTHLPNRATLTERLQTLLPKLK
KDEHLTLIYFGLRNFKSVNDSYGYLTGDSILVSLSQRLSLKLPDNWLLARIAGSEFVLAALHNASTEMTEQVIARVLSDC
SVPFTVNTNSITVQTNLGVAIAPVDATDSVSLLQRASAAMSIAKKEGAVVSFFGQETQKAAHERLLLESHLLDALHQGEL
AVYFQPLVSVRDKKRLVGAEALLRWHSPELGNVGPDRFIPLAESNGQIIEIGNFVLHEAMKHAAHWCKRSNNPFKIAINI
SPLQFRERQFVEHIEDLLDLYELPPGTLELEITEGILLQDEHHARASLARLRHLGVQISLDDFGTGYSSLSYLQKYAFDT
LKIDRSFISNLEFNEQNRELTRAIIAMAHKLKLNVVAEGVENAFQEAFIQAEECDFAQGYLYGKAIPAEKFAEKFTH

Specific function: Probable signaling protein whose physiological role is not yet known [H]

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=432, Percent_Identity=32.6388888888889, Blast_Score=244, Evalue=2e-65,
Organism=Escherichia coli, GI87081921, Length=447, Percent_Identity=31.7673378076063, Blast_Score=220, Evalue=2e-58,
Organism=Escherichia coli, GI226510982, Length=427, Percent_Identity=32.3185011709602, Blast_Score=186, Evalue=3e-48,
Organism=Escherichia coli, GI87081743, Length=241, Percent_Identity=37.344398340249, Blast_Score=155, Evalue=6e-39,
Organism=Escherichia coli, GI1790496, Length=240, Percent_Identity=31.6666666666667, Blast_Score=139, Evalue=5e-34,
Organism=Escherichia coli, GI87081980, Length=240, Percent_Identity=33.75, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI1788502, Length=242, Percent_Identity=33.4710743801653, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI1787055, Length=247, Percent_Identity=34.0080971659919, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI87081845, Length=239, Percent_Identity=32.6359832635983, Blast_Score=129, Evalue=6e-31,
Organism=Escherichia coli, GI1786507, Length=247, Percent_Identity=33.1983805668016, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1788849, Length=423, Percent_Identity=27.1867612293144, Blast_Score=119, Evalue=5e-28,
Organism=Escherichia coli, GI87082096, Length=424, Percent_Identity=26.4150943396226, Blast_Score=112, Evalue=7e-26,
Organism=Escherichia coli, GI87081977, Length=342, Percent_Identity=23.0994152046784, Blast_Score=86, Evalue=1e-17,
Organism=Escherichia coli, GI1788381, Length=427, Percent_Identity=23.1850117096019, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1787802, Length=84, Percent_Identity=38.0952380952381, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330
- InterPro:   IPR000014 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 71754; Mature: 71623

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSTPSGINTLPMPQINTKTISVPDAMLCGWQEIVDLVADITECPSALIMRIHEDDIEVF
CCCCCCCCCCCCCCCCCCEEECCCHHHHHCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHH
ASSRSAGNPYVPHARDALGHGLYCETVIRERQQLEVPNALKDPEWANNPDIKLGMICYCG
CCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEEEC
LPIFWPDNTPFGTICILDNKERHFNDRVHALLGRFQSALEGHLQILYHKSELKVLNEELE
CEEECCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEHHHHHHHHHHHH
HKVQERTQRLAELSARLLKEIEQRTAAEGHLEFHRTFDPLTHLPNRATLTERLQTLLPKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
KKDEHLTLIYFGLRNFKSVNDSYGYLTGDSILVSLSQRLSLKLPDNWLLARIAGSEFVLA
CCCCCEEEEEEEHHHHCCCCCCCCEEECCHHHHHHHHHCEEECCCCEEEEEECCCCEEEH
ALHNASTEMTEQVIARVLSDCSVPFTVNTNSITVQTNLGVAIAPVDATDSVSLLQRASAA
HHHCCCHHHHHHHHHHHHHCCCCCEEECCCEEEEEECCCEEEEECCCCCHHHHHHHHHHH
MSIAKKEGAVVSFFGQETQKAAHERLLLESHLLDALHQGELAVYFQPLVSVRDKKRLVGA
HHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHH
EALLRWHSPELGNVGPDRFIPLAESNGQIIEIGNFVLHEAMKHAAHWCKRSNNPFKIAIN
HHHHHHCCCCCCCCCCCCEEEEECCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCEEEEEE
ISPLQFRERQFVEHIEDLLDLYELPPGTLELEITEGILLQDEHHARASLARLRHLGVQIS
ECCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCEEECCCHHHHHHHHHHHHCCCEEE
LDDFGTGYSSLSYLQKYAFDTLKIDRSFISNLEFNEQNRELTRAIIAMAHKLKLNVVAEG
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VENAFQEAFIQAEECDFAQGYLYGKAIPAEKFAEKFTH
HHHHHHHHHHHHHCCCCHHCEEECCCCCHHHHHHHHCC
>Mature Secondary Structure 
TSTPSGINTLPMPQINTKTISVPDAMLCGWQEIVDLVADITECPSALIMRIHEDDIEVF
CCCCCCCCCCCCCCCCCEEECCCHHHHHCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHH
ASSRSAGNPYVPHARDALGHGLYCETVIRERQQLEVPNALKDPEWANNPDIKLGMICYCG
CCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEEEC
LPIFWPDNTPFGTICILDNKERHFNDRVHALLGRFQSALEGHLQILYHKSELKVLNEELE
CEEECCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEHHHHHHHHHHHH
HKVQERTQRLAELSARLLKEIEQRTAAEGHLEFHRTFDPLTHLPNRATLTERLQTLLPKL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
KKDEHLTLIYFGLRNFKSVNDSYGYLTGDSILVSLSQRLSLKLPDNWLLARIAGSEFVLA
CCCCCEEEEEEEHHHHCCCCCCCCEEECCHHHHHHHHHCEEECCCCEEEEEECCCCEEEH
ALHNASTEMTEQVIARVLSDCSVPFTVNTNSITVQTNLGVAIAPVDATDSVSLLQRASAA
HHHCCCHHHHHHHHHHHHHCCCCCEEECCCEEEEEECCCEEEEECCCCCHHHHHHHHHHH
MSIAKKEGAVVSFFGQETQKAAHERLLLESHLLDALHQGELAVYFQPLVSVRDKKRLVGA
HHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHH
EALLRWHSPELGNVGPDRFIPLAESNGQIIEIGNFVLHEAMKHAAHWCKRSNNPFKIAIN
HHHHHHCCCCCCCCCCCCEEEEECCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCEEEEEE
ISPLQFRERQFVEHIEDLLDLYELPPGTLELEITEGILLQDEHHARASLARLRHLGVQIS
ECCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCEEECCCHHHHHHHHHHHHCCCEEE
LDDFGTGYSSLSYLQKYAFDTLKIDRSFISNLEFNEQNRELTRAIIAMAHKLKLNVVAEG
ECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VENAFQEAFIQAEECDFAQGYLYGKAIPAEKFAEKFTH
HHHHHHHHHHHHHCCCCHHCEEECCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 11728710 [H]