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The map label for this gene is lptA [H]

Identifier: 119776218

GI number: 119776218

Start: 3662113

End: 3662667

Strand: Direct

Name: lptA [H]

Synonym: Sama_3086

Alternate gene names: 119776218

Gene position: 3662113-3662667 (Clockwise)

Preceding gene: 119776217

Following gene: 119776219

Centisome position: 85.04

GC content: 52.43

Gene sequence:

>555_bases
ATGAACCTAAATAAGTCGCTCATTCTGGTGCTGCTTTGCACCTGCAGCGCTGTGGCTTTGGCCAACACCAAGTTTGATTT
GAGCCAGGAAGTCAAAATTGCCGCAGCCAACAGTTATGCCGATCTGAAAAACAAGCGCATTGTATACGAAGGCCCGGTGA
CCCTGACCCAGGGCAGCCTGGTGCTTAAGGCGGGTGAACTGAGCTCTTTCACCGACGAGAAAAGCGGTAAACGCATTCTG
CTCGCCAAGGGTAACCCTGCCACTTACAGTCAGCAGGTGGAAGATGGCCGCACAGTGCATGCCAGTGCTACGGAAATCAG
CTACAACATCGACAGCCGTGTAATGAGCCTCAAAGGCAACGCCAAGGTCGAGCAGGATGGCAGCCAGGTGAGCGCCGACT
CCATCGTTTACGATATCGAAAAGCAGCAGCTCACGTCCCAAAGCAGCGGTAAAAAAGACGACCGGGTTATCACCATCATC
AAGCCCGAAAATTACCAGCAGGATCTGCAGGATAAAGTTAAGACAGAGCAACCCCAGCAAGAGAAGCAGCAATGA

Upstream 100 bases:

>100_bases
ATTATAATCAGCGGCAATAACTTCCACTTGAGCGGCCATGGTCTCTATGCTGATCTCAATGCCAAAGAAGTTAAGCTCTT
AAGCAAGATTAAGGGAACCT

Downstream 100 bases:

>100_bases
CCCAACTGACCCTGAAGGCCAGTAACCTCGCCAAGAGTTACAAAAACCGCCAGGTTGTCAAAAACGTCAGCCTCACCGTC
AATACCGGCCAGGTGGTCGG

Product: OstA-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 184; Mature: 184

Protein sequence:

>184_residues
MNLNKSLILVLLCTCSAVALANTKFDLSQEVKIAAANSYADLKNKRIVYEGPVTLTQGSLVLKAGELSSFTDEKSGKRIL
LAKGNPATYSQQVEDGRTVHASATEISYNIDSRVMSLKGNAKVEQDGSQVSADSIVYDIEKQQLTSQSSGKKDDRVITII
KPENYQQDLQDKVKTEQPQQEKQQ

Sequences:

>Translated_184_residues
MNLNKSLILVLLCTCSAVALANTKFDLSQEVKIAAANSYADLKNKRIVYEGPVTLTQGSLVLKAGELSSFTDEKSGKRIL
LAKGNPATYSQQVEDGRTVHASATEISYNIDSRVMSLKGNAKVEQDGSQVSADSIVYDIEKQQLTSQSSGKKDDRVITII
KPENYQQDLQDKVKTEQPQQEKQQ
>Mature_184_residues
MNLNKSLILVLLCTCSAVALANTKFDLSQEVKIAAANSYADLKNKRIVYEGPVTLTQGSLVLKAGELSSFTDEKSGKRIL
LAKGNPATYSQQVEDGRTVHASATEISYNIDSRVMSLKGNAKVEQDGSQVSADSIVYDIEKQQLTSQSSGKKDDRVITII
KPENYQQDLQDKVKTEQPQQEKQQ

Specific function: Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. May act as a chaperone that facilitates LPS transfer across the aquaeous environment of the periplasm. Interacts specifically with the lipid A domain

COG id: COG1934

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lptA family [H]

Homologues:

Organism=Escherichia coli, GI1789592, Length=182, Percent_Identity=30.2197802197802, Blast_Score=70, Evalue=7e-14,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014340
- InterPro:   IPR005653 [H]

Pfam domain/function: PF03968 OstA [H]

EC number: NA

Molecular weight: Translated: 20212; Mature: 20212

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLNKSLILVLLCTCSAVALANTKFDLSQEVKIAAANSYADLKNKRIVYEGPVTLTQGSL
CCCCHHHHHHHHHHHHHHEEECCCCCCCCCEEEEECCCCHHHCCCEEEEECCEEEECCCE
VLKAGELSSFTDEKSGKRILLAKGNPATYSQQVEDGRTVHASATEISYNIDSRVMSLKGN
EEEECCCCCCCCCCCCCEEEEECCCCCCCHHHHCCCCEEEEECEEEEECCCCEEEEECCC
AKVEQDGSQVSADSIVYDIEKQQLTSQSSGKKDDRVITIIKPENYQQDLQDKVKTEQPQQ
CEECCCCCEECCCCEEEECHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCHH
EKQQ
HHCC
>Mature Secondary Structure
MNLNKSLILVLLCTCSAVALANTKFDLSQEVKIAAANSYADLKNKRIVYEGPVTLTQGSL
CCCCHHHHHHHHHHHHHHEEECCCCCCCCCEEEEECCCCHHHCCCEEEEECCEEEECCCE
VLKAGELSSFTDEKSGKRILLAKGNPATYSQQVEDGRTVHASATEISYNIDSRVMSLKGN
EEEECCCCCCCCCCCCCEEEEECCCCCCCHHHHCCCCEEEEECEEEEECCCCEEEEECCC
AKVEQDGSQVSADSIVYDIEKQQLTSQSSGKKDDRVITIIKPENYQQDLQDKVKTEQPQQ
CEECCCCCEECCCCEEEECHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCHH
EKQQ
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]