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The map label for this gene is rnr [H]

Identifier: 119776199

GI number: 119776199

Start: 3644081

End: 3646507

Strand: Reverse

Name: rnr [H]

Synonym: Sama_3067

Alternate gene names: 119776199

Gene position: 3646507-3644081 (Counterclockwise)

Preceding gene: 119776200

Following gene: 119776198

Centisome position: 84.68

GC content: 56.65

Gene sequence:

>2427_bases
ATGATTAACGATCCGCATTTTGAGCGTGAACAGGAAAAATACGACAACCCCATCCCCAGCCGGGAATTTATCCTCGAATA
TTTGAGGTCTCAAACTTCTCCTCAGCCTCGCGACAGTATTGCCGAGGCCCTGAAAATCCATGATGAAGAGCGCTTGGAAG
CCCTGCGCCGCCGACTGCGCGCCATGGAGCGTGATGGCGAGCTGGTGTTTACCCGTGGCCAATGTTACGGCCTGCCCGAA
CGCATGGACTTGATGAGTGGTACTGTCCTTGGCCACAAAGATGGCTTTGGCTTTTTCCGCCCCGATAACGGTGGCGACGA
TCTTTTTATCAACGAGCGCGATATGCAGCTCTACTTCCATGGCGATAAGGTGCTGGCGCAAAAAGCCGGCGTTGACCGCC
GTGGTCGTCGCGATGCGCGCATTGTGAGGCTCTTGTCAGAGCGCAGCGCTGCCCTGGTGGGCCGCTTCTATGTTGATGCC
GGTATGGCCTTTGTGGTCGCGGATGACAAGCGTATTCCCCACGAAATCCTCATTGCCAACGAAGATAAAAATGGCGCCCG
CCACGGCGATGTGGTGGTGATCGAGCTGACCCGCCGCCCGGGACGTTACGTGCGTGCCGGTGGCAAGGTGACTGAGGTGC
TGGGCAAACAGATGGCACCTGGGATGGAGATCGAGATTGCCCTGCGCAATTACGACCTGCCACACCAGTGGTCAGCGGTG
ATTGAAAAGAAGCTGCGCCGCATCCCGGATTATGTCACCGATGAAGACAAGGAAGGCAGGGTCGATCTGCGAGAGCTGCC
ACTGGTTACCATAGACGGTGAAGATGCCCGCGACTTTGACGATGCTGTCTATGCCGAGCGTAAGCGTGGTGGCGGCTGGC
GCCTGTGGGTTGCCATTGCCGACGTGAGCCATTATGTGCGCACCGATTCAGCACTGGATAAAGAAGCCCGCGCCCGGGGG
AACTCCGTGTACTTCCCGTCGCAGGTGATCCCCATGCTGCCGGAAAAGCTCTCCAACGGTCTGTGCTCATTGAACCCGGG
TGTTGACCGCCTCTGTATGGTGGCAGAGATGACAATCTCCGCCAAGGGTGGTCTGTCGGGTTACAAGTTCTACCCAGCGG
TGATGCACTCCCATGCCCGCTTCACCTATACCCAGGTGGCGGCCATGCTGGAAGGTGGCGAGGTGAAAGACGAGCACAAG
GCCTTGTTCCCGCACCTTAAGGTGCTTCAAGAGTTGTATCTGTGTCTGGATGAGCAGCGTGCTGAGCGCGGCGCTATTGC
CTTTGAGACACTGGAAACCCAGTTTATTTTCAATGAGCAGCGCAAGATTGACCGCATTGTGCCCCGTGCCCGTAATCAGG
CCCACAAGATCATTGAAGAGTGCATGATTTTGGCCAACGTGGCCGCCGCCAAGTTTGTGATTAAACATAAGGGCCATGTG
CTTTATCGGGTGCACGAGAAGCCGTCAGAGCAAAAGCTGACCCAGTTTAAAGACTTCCTTGCCGAGCGCGGTTTGTCCAT
GACCGGCGGCCTCGAGCCCGAGCCTGCCGACTATTTGGCTCTGATGGCTCAGTTGGCCGGCAGACCTGATGCCGAGCTTA
TTCAGGTGATGCTGCTGCGCTCGATGCGTCAGGCCGTTTACACCCCGGATAACGAAGGTCACTTTGGCCTGGCGCTGGAA
GCTTACAGCCACTTTACCTCGCCCATTCGCCGCTACCCCGACTTGGTGCTGCACAGGGTTATCCGTTATCTGCTCGCCAA
AGAGCGGGGTGAAGCCAGTGAGAAGTGGACCGCCGATGGTGGCTACCACTATCAGCTGGAAGAGTTGGACCTCCTCGGTG
AAGAGTGCTCCAATACCGAGCGCCGTGCCGATGAAGCGACCCGGGATGTGTCCGACTGGCTTAAGTGTGAGTTTATGCAG
GACCACGTGGGTGACAGCTTCAGTGGTGTGATTGCCTCTGTGACCAGTTTTGGTCTGTTTGTGCGTCTGGATGAGCTCTT
TATCGATGGTCTGGTGCACATCTCCAGTTTGGGTAGCGATTACTTCCAGTACGACCCTCAGCGTCAGCGTCTGATCGGTG
AAAACTCTGGTCAGATCTACCAGATTGGCGATCCGGTGGCCGTGAAAGTTGCCTCGGTTAATCTGGACGACAGACAGATT
GATTTGCAGATGGAAGGTGAGCGCCCGGGCCGCAAAAAGGCTGGCAAGAAGCCAACGACCGCCCGTGACAGAGCCAATCT
TGAAGGTGCCCGCACTGGTAACGGCAAGCCCGGTAAAGGCGGTAGCGTGCGCAGCCAGTTGGCCGGCGGCAAATTGGGGG
GCTCTGAGACCAAAAAAAGAGACGCCAAGGCCAAAGACGGTAAGAAACCCAAAAAGGCGGCAGAAGCCAAGCCCAAGGCC
GCTAAACGAGTTAAGAGAAAGAAATAA

Upstream 100 bases:

>100_bases
ATCTATGATGCCCGCCAGTGCCGTGGCCAGAGCCCGGGGTGAGCATCTTTGGAATTACTGACACCCGGGCAGGGGCCTGG
GTGAACTCAATGGAAACTGA

Downstream 100 bases:

>100_bases
ATGAAAAAACAGGAATTGGTGTTTGGCATTCATGCGGTCGAGTCTGTGCTAAAGCATGCCCCCGAGCGCGTGCTCGAGTT
GTGGCTGATGACCGGCCGTC

Product: exoribonuclease II

Products: NA

Alternate protein names: RNase R [H]

Number of amino acids: Translated: 808; Mature: 808

Protein sequence:

>808_residues
MINDPHFEREQEKYDNPIPSREFILEYLRSQTSPQPRDSIAEALKIHDEERLEALRRRLRAMERDGELVFTRGQCYGLPE
RMDLMSGTVLGHKDGFGFFRPDNGGDDLFINERDMQLYFHGDKVLAQKAGVDRRGRRDARIVRLLSERSAALVGRFYVDA
GMAFVVADDKRIPHEILIANEDKNGARHGDVVVIELTRRPGRYVRAGGKVTEVLGKQMAPGMEIEIALRNYDLPHQWSAV
IEKKLRRIPDYVTDEDKEGRVDLRELPLVTIDGEDARDFDDAVYAERKRGGGWRLWVAIADVSHYVRTDSALDKEARARG
NSVYFPSQVIPMLPEKLSNGLCSLNPGVDRLCMVAEMTISAKGGLSGYKFYPAVMHSHARFTYTQVAAMLEGGEVKDEHK
ALFPHLKVLQELYLCLDEQRAERGAIAFETLETQFIFNEQRKIDRIVPRARNQAHKIIEECMILANVAAAKFVIKHKGHV
LYRVHEKPSEQKLTQFKDFLAERGLSMTGGLEPEPADYLALMAQLAGRPDAELIQVMLLRSMRQAVYTPDNEGHFGLALE
AYSHFTSPIRRYPDLVLHRVIRYLLAKERGEASEKWTADGGYHYQLEELDLLGEECSNTERRADEATRDVSDWLKCEFMQ
DHVGDSFSGVIASVTSFGLFVRLDELFIDGLVHISSLGSDYFQYDPQRQRLIGENSGQIYQIGDPVAVKVASVNLDDRQI
DLQMEGERPGRKKAGKKPTTARDRANLEGARTGNGKPGKGGSVRSQLAGGKLGGSETKKRDAKAKDGKKPKKAAEAKPKA
AKRVKRKK

Sequences:

>Translated_808_residues
MINDPHFEREQEKYDNPIPSREFILEYLRSQTSPQPRDSIAEALKIHDEERLEALRRRLRAMERDGELVFTRGQCYGLPE
RMDLMSGTVLGHKDGFGFFRPDNGGDDLFINERDMQLYFHGDKVLAQKAGVDRRGRRDARIVRLLSERSAALVGRFYVDA
GMAFVVADDKRIPHEILIANEDKNGARHGDVVVIELTRRPGRYVRAGGKVTEVLGKQMAPGMEIEIALRNYDLPHQWSAV
IEKKLRRIPDYVTDEDKEGRVDLRELPLVTIDGEDARDFDDAVYAERKRGGGWRLWVAIADVSHYVRTDSALDKEARARG
NSVYFPSQVIPMLPEKLSNGLCSLNPGVDRLCMVAEMTISAKGGLSGYKFYPAVMHSHARFTYTQVAAMLEGGEVKDEHK
ALFPHLKVLQELYLCLDEQRAERGAIAFETLETQFIFNEQRKIDRIVPRARNQAHKIIEECMILANVAAAKFVIKHKGHV
LYRVHEKPSEQKLTQFKDFLAERGLSMTGGLEPEPADYLALMAQLAGRPDAELIQVMLLRSMRQAVYTPDNEGHFGLALE
AYSHFTSPIRRYPDLVLHRVIRYLLAKERGEASEKWTADGGYHYQLEELDLLGEECSNTERRADEATRDVSDWLKCEFMQ
DHVGDSFSGVIASVTSFGLFVRLDELFIDGLVHISSLGSDYFQYDPQRQRLIGENSGQIYQIGDPVAVKVASVNLDDRQI
DLQMEGERPGRKKAGKKPTTARDRANLEGARTGNGKPGKGGSVRSQLAGGKLGGSETKKRDAKAKDGKKPKKAAEAKPKA
AKRVKRKK
>Mature_808_residues
MINDPHFEREQEKYDNPIPSREFILEYLRSQTSPQPRDSIAEALKIHDEERLEALRRRLRAMERDGELVFTRGQCYGLPE
RMDLMSGTVLGHKDGFGFFRPDNGGDDLFINERDMQLYFHGDKVLAQKAGVDRRGRRDARIVRLLSERSAALVGRFYVDA
GMAFVVADDKRIPHEILIANEDKNGARHGDVVVIELTRRPGRYVRAGGKVTEVLGKQMAPGMEIEIALRNYDLPHQWSAV
IEKKLRRIPDYVTDEDKEGRVDLRELPLVTIDGEDARDFDDAVYAERKRGGGWRLWVAIADVSHYVRTDSALDKEARARG
NSVYFPSQVIPMLPEKLSNGLCSLNPGVDRLCMVAEMTISAKGGLSGYKFYPAVMHSHARFTYTQVAAMLEGGEVKDEHK
ALFPHLKVLQELYLCLDEQRAERGAIAFETLETQFIFNEQRKIDRIVPRARNQAHKIIEECMILANVAAAKFVIKHKGHV
LYRVHEKPSEQKLTQFKDFLAERGLSMTGGLEPEPADYLALMAQLAGRPDAELIQVMLLRSMRQAVYTPDNEGHFGLALE
AYSHFTSPIRRYPDLVLHRVIRYLLAKERGEASEKWTADGGYHYQLEELDLLGEECSNTERRADEATRDVSDWLKCEFMQ
DHVGDSFSGVIASVTSFGLFVRLDELFIDGLVHISSLGSDYFQYDPQRQRLIGENSGQIYQIGDPVAVKVASVNLDDRQI
DLQMEGERPGRKKAGKKPTTARDRANLEGARTGNGKPGKGGSVRSQLAGGKLGGSETKKRDAKAKDGKKPKKAAEAKPKA
AKRVKRKK

Specific function: 3'-5'exoribonuclease that participates in an essential cell function. Acts nonspecifically on poly(A), poly(U) and ribosomal RNAs [H]

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Homo sapiens, GI190014623, Length=589, Percent_Identity=29.3718166383701, Blast_Score=187, Evalue=4e-47,
Organism=Homo sapiens, GI190014625, Length=589, Percent_Identity=29.3718166383701, Blast_Score=187, Evalue=4e-47,
Organism=Homo sapiens, GI134288890, Length=412, Percent_Identity=30.3398058252427, Blast_Score=149, Evalue=8e-36,
Organism=Homo sapiens, GI19115966, Length=515, Percent_Identity=25.631067961165, Blast_Score=146, Evalue=6e-35,
Organism=Homo sapiens, GI219521928, Length=515, Percent_Identity=25.631067961165, Blast_Score=146, Evalue=9e-35,
Organism=Homo sapiens, GI156105695, Length=553, Percent_Identity=25.3164556962025, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI156105693, Length=553, Percent_Identity=25.3164556962025, Blast_Score=77, Evalue=6e-14,
Organism=Escherichia coli, GI87082383, Length=744, Percent_Identity=59.8118279569892, Blast_Score=924, Evalue=0.0,
Organism=Escherichia coli, GI1787542, Length=651, Percent_Identity=27.0353302611367, Blast_Score=176, Evalue=4e-45,
Organism=Caenorhabditis elegans, GI17553506, Length=508, Percent_Identity=28.9370078740157, Blast_Score=162, Evalue=9e-40,
Organism=Caenorhabditis elegans, GI212645896, Length=394, Percent_Identity=29.4416243654822, Blast_Score=159, Evalue=8e-39,
Organism=Saccharomyces cerevisiae, GI6324552, Length=504, Percent_Identity=28.1746031746032, Blast_Score=158, Evalue=3e-39,
Organism=Saccharomyces cerevisiae, GI6320499, Length=549, Percent_Identity=21.8579234972678, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24649634, Length=435, Percent_Identity=28.735632183908, Blast_Score=172, Evalue=8e-43,
Organism=Drosophila melanogaster, GI24654592, Length=360, Percent_Identity=27.7777777777778, Blast_Score=137, Evalue=4e-32,
Organism=Drosophila melanogaster, GI19922976, Length=360, Percent_Identity=27.7777777777778, Blast_Score=137, Evalue=4e-32,
Organism=Drosophila melanogaster, GI24654597, Length=360, Percent_Identity=27.7777777777778, Blast_Score=137, Evalue=4e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR013223
- InterPro:   IPR001900
- InterPro:   IPR022966
- InterPro:   IPR004476
- InterPro:   IPR011805
- InterPro:   IPR013668 [H]

Pfam domain/function: PF08461 HTH_12; PF08206 OB_RNB; PF00773 RNB; PF00575 S1 [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 91176; Mature: 91176

Theoretical pI: Translated: 8.26; Mature: 8.26

Prosite motif: PS00018 EF_HAND_1 ; PS50126 S1 ; PS01175 RIBONUCLEASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINDPHFEREQEKYDNPIPSREFILEYLRSQTSPQPRDSIAEALKIHDEERLEALRRRLR
CCCCCCCCCHHHHCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHH
AMERDGELVFTRGQCYGLPERMDLMSGTVLGHKDGFGFFRPDNGGDDLFINERDMQLYFH
HHCCCCCEEEECCCCCCCHHHHHHHHCCEEECCCCCCCCCCCCCCCCEEEECCCEEEEEC
GDKVLAQKAGVDRRGRRDARIVRLLSERSAALVGRFYVDAGMAFVVADDKRIPHEILIAN
CCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCEEEEEE
EDKNGARHGDVVVIELTRRPGRYVRAGGKVTEVLGKQMAPGMEIEIALRNYDLPHQWSAV
CCCCCCCCCCEEEEEECCCCCCEEECCCHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHH
IEKKLRRIPDYVTDEDKEGRVDLRELPLVTIDGEDARDFDDAVYAERKRGGGWRLWVAIA
HHHHHHHCCCCCCCCCCCCCCCHHHCCEEEECCCCCCCHHHHHHHHHHCCCCEEEEEEEE
DVSHYVRTDSALDKEARARGNSVYFPSQVIPMLPEKLSNGLCSLNPGVDRLCMVAEMTIS
HHHHHHHCCHHHCHHHHHCCCCEECCHHHHHHCHHHHCCCCEECCCCHHHHHHHHHHHEE
AKGGLSGYKFYPAVMHSHARFTYTQVAAMLEGGEVKDEHKALFPHLKVLQELYLCLDEQR
CCCCCCCCCHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AERGAIAFETLETQFIFNEQRKIDRIVPRARNQAHKIIEECMILANVAAAKFVIKHKGHV
HHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
LYRVHEKPSEQKLTQFKDFLAERGLSMTGGLEPEPADYLALMAQLAGRPDAELIQVMLLR
EEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHH
SMRQAVYTPDNEGHFGLALEAYSHFTSPIRRYPDLVLHRVIRYLLAKERGEASEKWTADG
HHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
GYHYQLEELDLLGEECSNTERRADEATRDVSDWLKCEFMQDHVGDSFSGVIASVTSFGLF
CEEEEHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
VRLDELFIDGLVHISSLGSDYFQYDPQRQRLIGENSGQIYQIGDPVAVKVASVNLDDRQI
HHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHCCCCCCCEEECCCCEEEEEEEECCCCCEE
DLQMEGERPGRKKAGKKPTTARDRANLEGARTGNGKPGKGGSVRSQLAGGKLGGSETKKR
EEEECCCCCCHHHCCCCCCCCHHHCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCHHHHH
DAKAKDGKKPKKAAEAKPKAAKRVKRKK
CCCCCCCCCCHHHHCCCCHHHHHHHCCC
>Mature Secondary Structure
MINDPHFEREQEKYDNPIPSREFILEYLRSQTSPQPRDSIAEALKIHDEERLEALRRRLR
CCCCCCCCCHHHHCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHH
AMERDGELVFTRGQCYGLPERMDLMSGTVLGHKDGFGFFRPDNGGDDLFINERDMQLYFH
HHCCCCCEEEECCCCCCCHHHHHHHHCCEEECCCCCCCCCCCCCCCCEEEECCCEEEEEC
GDKVLAQKAGVDRRGRRDARIVRLLSERSAALVGRFYVDAGMAFVVADDKRIPHEILIAN
CCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCEEEEEE
EDKNGARHGDVVVIELTRRPGRYVRAGGKVTEVLGKQMAPGMEIEIALRNYDLPHQWSAV
CCCCCCCCCCEEEEEECCCCCCEEECCCHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHH
IEKKLRRIPDYVTDEDKEGRVDLRELPLVTIDGEDARDFDDAVYAERKRGGGWRLWVAIA
HHHHHHHCCCCCCCCCCCCCCCHHHCCEEEECCCCCCCHHHHHHHHHHCCCCEEEEEEEE
DVSHYVRTDSALDKEARARGNSVYFPSQVIPMLPEKLSNGLCSLNPGVDRLCMVAEMTIS
HHHHHHHCCHHHCHHHHHCCCCEECCHHHHHHCHHHHCCCCEECCCCHHHHHHHHHHHEE
AKGGLSGYKFYPAVMHSHARFTYTQVAAMLEGGEVKDEHKALFPHLKVLQELYLCLDEQR
CCCCCCCCCHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
AERGAIAFETLETQFIFNEQRKIDRIVPRARNQAHKIIEECMILANVAAAKFVIKHKGHV
HHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
LYRVHEKPSEQKLTQFKDFLAERGLSMTGGLEPEPADYLALMAQLAGRPDAELIQVMLLR
EEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHH
SMRQAVYTPDNEGHFGLALEAYSHFTSPIRRYPDLVLHRVIRYLLAKERGEASEKWTADG
HHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
GYHYQLEELDLLGEECSNTERRADEATRDVSDWLKCEFMQDHVGDSFSGVIASVTSFGLF
CEEEEHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
VRLDELFIDGLVHISSLGSDYFQYDPQRQRLIGENSGQIYQIGDPVAVKVASVNLDDRQI
HHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHCCCCCCCEEECCCCEEEEEEEECCCCCEE
DLQMEGERPGRKKAGKKPTTARDRANLEGARTGNGKPGKGGSVRSQLAGGKLGGSETKKR
EEEECCCCCCHHHCCCCCCCCHHHCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCHHHHH
DAKAKDGKKPKKAAEAKPKAAKRVKRKK
CCCCCCCCCCHHHHCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]