Click here to switch to the map view.

The map label for this gene is hflC [H]

Identifier: 119776154

GI number: 119776154

Start: 3596256

End: 3597182

Strand: Reverse

Name: hflC [H]

Synonym: Sama_3022

Alternate gene names: 119776154

Gene position: 3597182-3596256 (Counterclockwise)

Preceding gene: 119776155

Following gene: 119776153

Centisome position: 83.54

GC content: 52.43

Gene sequence:

>927_bases
ATGAGTCGTTTAATATTGGTTATTCTGGTGGTGGTGATTGCTGTGATGAGTTCGTCTCTCATGGTAGTCAACGAGGGTGA
ACGTGCCATCGTGTCGCGCTTTAACGCCATCGTAAAAGAAAACGTTGACGGTACCGAGCGCACCAAGGTGTTCGAACCTG
GTTTGCATTTCAAGATGCCCTTTATCGATACAGTGCGTAATCTCGATGCCCGGGTGCAAACCCTGGATGGGGCTGCAGAC
CGTTTCGTGACTTCCGAGAAGAAAGACCTGATGGTGGATTCTTACGTGAAGTGGCGCATCCAGGACTTCGAAAAGTACTA
CCTGTCTACCAACGGTGGTATCAAGTCCAATGCTGAAGCTCTGCTGCAGCGCAAGGTGAACAGCGACCTGCGTACCGAGT
TTGGTCAGCGCACCATTAAGGAAATTGTATCCGGCGTACGTGCTGGCGAAGCCATCGACAAGGAAAACTCCGGTCGTGAC
GAGCTGCAACGCAACGCTCTGGAAAATGTCCGCAAGAGTGCCGAAGACCTCGGGATTGAAGTGGTCGACGTACGGGTGAA
GCAGATTAACCTGCCAACCAATGTGAGCTCTTCCATCTTCCAACGTATGCGTGCCGAGCGTCAGGCCGTGGCGAAAGAAC
ATCGCGCCAAAGGTCGTGAGGAAGCCGAAAAGATCCGTGCAACCGCCGATGCCAACGTCGTGGTTCGCCTCTCCAACGCC
CAGCGTAACGCCCAGGTGATCCGCGGTGATGGTGATGCAGTAGCGGCCAAGATTTATGCCGACGCTTACAAGAAGGACCC
TGAGTTCTATGCCTTCCTGAGAAGTCTTGATGCCTACAAGGCGAGCTTCTCTGGTAGCGGCAACATGATGGTGCTTGAAC
CGGATAGTGAATTCTTCCGCTATATGAAAGAATCCAAACCAAAATAA

Upstream 100 bases:

>100_bases
CACGCATCTGGATACCGGCGCCTTACAGCGCAGTACCGGACTGCCGGTAAGCGGCCGTCCTTCCCGTGAAGATCGTGTTC
GCCAGGGGAGGGAGTAAGTT

Downstream 100 bases:

>100_bases
TCATCATCAGTACTAAAAAAGCCCAACTCTGATAGTTGGGCTTTTTTTATGAATTTTGCTTTGTGAAAGCCAAGGTTAAA
CGGCCAATCGCTGCAATTTT

Product: hflC protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MSRLILVILVVVIAVMSSSLMVVNEGERAIVSRFNAIVKENVDGTERTKVFEPGLHFKMPFIDTVRNLDARVQTLDGAAD
RFVTSEKKDLMVDSYVKWRIQDFEKYYLSTNGGIKSNAEALLQRKVNSDLRTEFGQRTIKEIVSGVRAGEAIDKENSGRD
ELQRNALENVRKSAEDLGIEVVDVRVKQINLPTNVSSSIFQRMRAERQAVAKEHRAKGREEAEKIRATADANVVVRLSNA
QRNAQVIRGDGDAVAAKIYADAYKKDPEFYAFLRSLDAYKASFSGSGNMMVLEPDSEFFRYMKESKPK

Sequences:

>Translated_308_residues
MSRLILVILVVVIAVMSSSLMVVNEGERAIVSRFNAIVKENVDGTERTKVFEPGLHFKMPFIDTVRNLDARVQTLDGAAD
RFVTSEKKDLMVDSYVKWRIQDFEKYYLSTNGGIKSNAEALLQRKVNSDLRTEFGQRTIKEIVSGVRAGEAIDKENSGRD
ELQRNALENVRKSAEDLGIEVVDVRVKQINLPTNVSSSIFQRMRAERQAVAKEHRAKGREEAEKIRATADANVVVRLSNA
QRNAQVIRGDGDAVAAKIYADAYKKDPEFYAFLRSLDAYKASFSGSGNMMVLEPDSEFFRYMKESKPK
>Mature_307_residues
SRLILVILVVVIAVMSSSLMVVNEGERAIVSRFNAIVKENVDGTERTKVFEPGLHFKMPFIDTVRNLDARVQTLDGAADR
FVTSEKKDLMVDSYVKWRIQDFEKYYLSTNGGIKSNAEALLQRKVNSDLRTEFGQRTIKEIVSGVRAGEAIDKENSGRDE
LQRNALENVRKSAEDLGIEVVDVRVKQINLPTNVSSSIFQRMRAERQAVAKEHRAKGREEAEKIRATADANVVVRLSNAQ
RNAQVIRGDGDAVAAKIYADAYKKDPEFYAFLRSLDAYKASFSGSGNMMVLEPDSEFFRYMKESKPK

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790617, Length=312, Percent_Identity=53.525641025641, Blast_Score=316, Evalue=1e-87,
Organism=Escherichia coli, GI1786697, Length=269, Percent_Identity=20.817843866171, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010200
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: 3.4.-.-

Molecular weight: Translated: 34681; Mature: 34550

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRLILVILVVVIAVMSSSLMVVNEGERAIVSRFNAIVKENVDGTERTKVFEPGLHFKMP
CHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHCCCCCCHHHEEECCCCCEECC
FIDTVRNLDARVQTLDGAADRFVTSEKKDLMVDSYVKWRIQDFEKYYLSTNGGIKSNAEA
HHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
LLQRKVNSDLRTEFGQRTIKEIVSGVRAGEAIDKENSGRDELQRNALENVRKSAEDLGIE
HHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEE
VVDVRVKQINLPTNVSSSIFQRMRAERQAVAKEHRAKGREEAEKIRATADANVVVRLSNA
EEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEEECCC
QRNAQVIRGDGDAVAAKIYADAYKKDPEFYAFLRSLDAYKASFSGSGNMMVLEPDSEFFR
CCCCEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHH
YMKESKPK
HHHHCCCC
>Mature Secondary Structure 
SRLILVILVVVIAVMSSSLMVVNEGERAIVSRFNAIVKENVDGTERTKVFEPGLHFKMP
HHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHCCCCCCHHHEEECCCCCEECC
FIDTVRNLDARVQTLDGAADRFVTSEKKDLMVDSYVKWRIQDFEKYYLSTNGGIKSNAEA
HHHHHHHHHHHHHHHCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
LLQRKVNSDLRTEFGQRTIKEIVSGVRAGEAIDKENSGRDELQRNALENVRKSAEDLGIE
HHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEE
VVDVRVKQINLPTNVSSSIFQRMRAERQAVAKEHRAKGREEAEKIRATADANVVVRLSNA
EEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEEECCC
QRNAQVIRGDGDAVAAKIYADAYKKDPEFYAFLRSLDAYKASFSGSGNMMVLEPDSEFFR
CCCCEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHH
YMKESKPK
HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]