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The map label for this gene is adrA [H]

Identifier: 119776148

GI number: 119776148

Start: 3591042

End: 3592199

Strand: Direct

Name: adrA [H]

Synonym: Sama_3016

Alternate gene names: 119776148

Gene position: 3591042-3592199 (Clockwise)

Preceding gene: 119776139

Following gene: 119776165

Centisome position: 83.39

GC content: 51.04

Gene sequence:

>1158_bases
ATGATTATCAAACCTTCGTCAGTAAACTCTATGGCATTTTGGGGGAAACGGCTGCTCAGTTACGCCAAAACGGGTATAGA
GCATTGTCACGGCAAAACGCAGGAACGCCGGCTCATCCAAACAAATATCAGTGTGTTTATTGCGGTCATCACCATATTGG
TGTTTAACCTTGCCTTTGTGCTGCTTGGCAATCCGGGGTTGATGTATTCAGGGCTGGTGCAACTCCCATTTTTACTGTTA
TTACCGCTGGTGCTTTGGTTCAACCGCAAAGGGCGAAGACACGAGGCGACTCTGACCCTGTTTTTATTGGTGATGCTGGA
TGCGGTTAGCGCGCTTATGCTCGCTCAAGGGGTGACACTTGGACTTCAGTACTATTTTCTGATGTTTGCGGTGTTACCGG
CATCCTATCTGGACGCCAAACATTGGCCGACCACCTTACTGCTGTTTTTAAGTAACATTCTGCTATTTGGCTATTTCGAA
GTGTATGGCTGGCAAGCTCACCCCAGCATTGCCGAAGTGCCGACATTCACCATCACACTGCTCAGAATAATAATGGTGGG
TTCATGCGCAACCACGGTATTGGTGGTTATCCTGATAAGTGAGTACTACGCTGCACAAAATGAACAGGAACTGCAATATC
TTGCGGATACGGACTCGCTGACCGGGCTGCCAAACCGGCGTGCTTTCATGGGGCGCCTGGAACGAACCATCAAAGACAGA
CGATCCTTTAGCCTGCTGATTATCGATGTTGACCATTTCAAGCAGATTAACGACACCACGGGGCACCAGACTGGCGACGC
TGCACTGCAATTTTTGGCTAACCAGCTTAATGCGTGCATTCAGGGGGAAGACTTTGCCGGGCGGATTGGCGGCGAAGAGT
TTGCTATGGTGCAGTTTTGCGCTTCGCCACTTGAGCATCTGGTCCGTGCCGAAAGTCTGCGAAAAACCATTGCCTCGGCA
CATCCAGACCTGGGCGTTGGCCCCGTATATTTAACGGTTTCCATCGGTGTGTGCATGGCAACACCGCCGGTGTCACTTAT
CACACTGATGGCCATGGCAGACAATGCACTCTATGAGGCCAAACGCAGTGGTCGCAACTGCGTCCAGGTAGCCGCCGCAA
AATCTGAATCCGTGCCGCCATGGCAGGCAGTTACATGA

Upstream 100 bases:

>100_bases
TTCGTCCGCGCGTTGAAATCCAAACAGAACAGGCCGCGAATCCTAGCACAGAGCGGCCTGCGGATCATCCAATGGCCGGA
ACTATGTCTATGCTTAAGGG

Downstream 100 bases:

>100_bases
TGGGGATGCCAAAACGAAAAAACCAGCCGATGGCTGGTTTTTGTATTATTTGACCACAGTTAAATGGCCGCGGCGTTTGG
GACTGGGATCGTCCGGCCCA

Product: GGDEF domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MIIKPSSVNSMAFWGKRLLSYAKTGIEHCHGKTQERRLIQTNISVFIAVITILVFNLAFVLLGNPGLMYSGLVQLPFLLL
LPLVLWFNRKGRRHEATLTLFLLVMLDAVSALMLAQGVTLGLQYYFLMFAVLPASYLDAKHWPTTLLLFLSNILLFGYFE
VYGWQAHPSIAEVPTFTITLLRIIMVGSCATTVLVVILISEYYAAQNEQELQYLADTDSLTGLPNRRAFMGRLERTIKDR
RSFSLLIIDVDHFKQINDTTGHQTGDAALQFLANQLNACIQGEDFAGRIGGEEFAMVQFCASPLEHLVRAESLRKTIASA
HPDLGVGPVYLTVSIGVCMATPPVSLITLMAMADNALYEAKRSGRNCVQVAAAKSESVPPWQAVT

Sequences:

>Translated_385_residues
MIIKPSSVNSMAFWGKRLLSYAKTGIEHCHGKTQERRLIQTNISVFIAVITILVFNLAFVLLGNPGLMYSGLVQLPFLLL
LPLVLWFNRKGRRHEATLTLFLLVMLDAVSALMLAQGVTLGLQYYFLMFAVLPASYLDAKHWPTTLLLFLSNILLFGYFE
VYGWQAHPSIAEVPTFTITLLRIIMVGSCATTVLVVILISEYYAAQNEQELQYLADTDSLTGLPNRRAFMGRLERTIKDR
RSFSLLIIDVDHFKQINDTTGHQTGDAALQFLANQLNACIQGEDFAGRIGGEEFAMVQFCASPLEHLVRAESLRKTIASA
HPDLGVGPVYLTVSIGVCMATPPVSLITLMAMADNALYEAKRSGRNCVQVAAAKSESVPPWQAVT
>Mature_385_residues
MIIKPSSVNSMAFWGKRLLSYAKTGIEHCHGKTQERRLIQTNISVFIAVITILVFNLAFVLLGNPGLMYSGLVQLPFLLL
LPLVLWFNRKGRRHEATLTLFLLVMLDAVSALMLAQGVTLGLQYYFLMFAVLPASYLDAKHWPTTLLLFLSNILLFGYFE
VYGWQAHPSIAEVPTFTITLLRIIMVGSCATTVLVVILISEYYAAQNEQELQYLADTDSLTGLPNRRAFMGRLERTIKDR
RSFSLLIIDVDHFKQINDTTGHQTGDAALQFLANQLNACIQGEDFAGRIGGEEFAMVQFCASPLEHLVRAESLRKTIASA
HPDLGVGPVYLTVSIGVCMATPPVSLITLMAMADNALYEAKRSGRNCVQVAAAKSESVPPWQAVT

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI1786584, Length=178, Percent_Identity=37.0786516853933, Blast_Score=108, Evalue=7e-25,
Organism=Escherichia coli, GI87081881, Length=169, Percent_Identity=39.0532544378698, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1787802, Length=185, Percent_Identity=32.4324324324324, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI145693134, Length=161, Percent_Identity=38.5093167701863, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1787262, Length=163, Percent_Identity=33.1288343558282, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI87082007, Length=178, Percent_Identity=34.2696629213483, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1787816, Length=157, Percent_Identity=34.3949044585987, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1788085, Length=168, Percent_Identity=32.1428571428571, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787541, Length=194, Percent_Identity=28.8659793814433, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1788956, Length=168, Percent_Identity=37.5, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI87081974, Length=151, Percent_Identity=30.4635761589404, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1788381, Length=204, Percent_Identity=31.8627450980392, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87081977, Length=151, Percent_Identity=33.112582781457, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1787056, Length=170, Percent_Identity=31.1764705882353, Blast_Score=68, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR007894 [H]

Pfam domain/function: PF00990 GGDEF; PF05230 MASE2 [H]

EC number: NA

Molecular weight: Translated: 42620; Mature: 42620

Theoretical pI: Translated: 7.87; Mature: 7.87

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIKPSSVNSMAFWGKRLLSYAKTGIEHCHGKTQERRLIQTNISVFIAVITILVFNLAFV
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLGNPGLMYSGLVQLPFLLLLPLVLWFNRKGRRHEATLTLFLLVMLDAVSALMLAQGVTL
HHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLQYYFLMFAVLPASYLDAKHWPTTLLLFLSNILLFGYFEVYGWQAHPSIAEVPTFTITL
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
LRIIMVGSCATTVLVVILISEYYAAQNEQELQYLADTDSLTGLPNRRAFMGRLERTIKDR
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHC
RSFSLLIIDVDHFKQINDTTGHQTGDAALQFLANQLNACIQGEDFAGRIGGEEFAMVQFC
CCEEEEEEEHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
ASPLEHLVRAESLRKTIASAHPDLGVGPVYLTVSIGVCMATPPVSLITLMAMADNALYEA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEHHHHHCCCHHHHHHHHHHHHHHHHHH
KRSGRNCVQVAAAKSESVPPWQAVT
HHCCCHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MIIKPSSVNSMAFWGKRLLSYAKTGIEHCHGKTQERRLIQTNISVFIAVITILVFNLAFV
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLGNPGLMYSGLVQLPFLLLLPLVLWFNRKGRRHEATLTLFLLVMLDAVSALMLAQGVTL
HHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLQYYFLMFAVLPASYLDAKHWPTTLLLFLSNILLFGYFEVYGWQAHPSIAEVPTFTITL
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
LRIIMVGSCATTVLVVILISEYYAAQNEQELQYLADTDSLTGLPNRRAFMGRLERTIKDR
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHC
RSFSLLIIDVDHFKQINDTTGHQTGDAALQFLANQLNACIQGEDFAGRIGGEEFAMVQFC
CCEEEEEEEHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
ASPLEHLVRAESLRKTIASAHPDLGVGPVYLTVSIGVCMATPPVSLITLMAMADNALYEA
HHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEHHHHHCCCHHHHHHHHHHHHHHHHHH
KRSGRNCVQVAAAKSESVPPWQAVT
HHCCCHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]