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The map label for this gene is nrfC [H]

Identifier: 119776035

GI number: 119776035

Start: 3450625

End: 3451317

Strand: Direct

Name: nrfC [H]

Synonym: Sama_2903

Alternate gene names: 119776035

Gene position: 3450625-3451317 (Clockwise)

Preceding gene: 119776034

Following gene: 119776036

Centisome position: 80.13

GC content: 58.87

Gene sequence:

>693_bases
ATGCTAGTTTCCAAACGCCAGTTTCTCAAGGGGGTTGGGGCGCTGCTGACCGGTGTCTCTGTGTATGGAGCCACCCGCAC
GCTCCAGGCCGATTCCCTGCTGCAACCCGAGGCGGAAAGCGAAACCAAATATGCCATGGTGCACGATGAAAATGCCTGCA
TCGGCTGTAATGCCTGTGTCCAGGCGTGCCGTGAGACCAATCAGATCCCCGAGGGTGTCACCCGGGTGAAGATAGAGCGC
AGGGGCCCCTTTGGTGAGTATCCTAACCAGAGCTACCGCTTCAGCCGTGTCTCCTGTCAGCATTGCGAAGCCGCGCCCTG
TGTGCGGGTCTGCCCCACAGGCGCTGCCTATATCGACAAAGAGACCGGCATTGTGGCGGTCAACAGCGACCGCTGCGTGG
GTTGCCAGTATTGCATTGCCGCCTGCCCCTATCAGGTCAGGTATATCCACCCCGAGACCCGCACCGCCGACAAATGCGAT
TTCTGTCAGAAGAGTCGCCTGGCTCAGGGGCTGCAACCTGCCTGTGTCGAAGCCTGCCCCACCAAGGCACTGACCTTCGG
CAATCTCAAGGATCCCGAGTCGGAATTGGTCAAGTTGCTTAAAGCCAAGCCCAGCTACCGCGCCAAGGTGGACCTGGGGA
CCCGGCCCAAGCTGTTCCATATTCAAACCATAGATGGGGAGATAATGCTATGA

Upstream 100 bases:

>100_bases
CGACTCCATCCCGAATCGGACCCCATGTTGTCGCTCTCACCGCAACAACATAGCCAGCTGTGCGTCAGCTGCCACAAAGT
CGAACAATAGGAGGCCTGTC

Downstream 100 bases:

>100_bases
GCGCTTTTCATTTCGAAGGCCTGGTATGGCATTGGCCTATCGCCATTTACCTCTTCCTGGCGGGTCTGTCTGCTGGGGCG
GTATTTTTCGCCATCATGCT

Product: NrfC, Fe-S-cluster-containing hydrogenase component 1

Products: oxidized cytochrome C552; NH3 [C]

Alternate protein names: NA

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MLVSKRQFLKGVGALLTGVSVYGATRTLQADSLLQPEAESETKYAMVHDENACIGCNACVQACRETNQIPEGVTRVKIER
RGPFGEYPNQSYRFSRVSCQHCEAAPCVRVCPTGAAYIDKETGIVAVNSDRCVGCQYCIAACPYQVRYIHPETRTADKCD
FCQKSRLAQGLQPACVEACPTKALTFGNLKDPESELVKLLKAKPSYRAKVDLGTRPKLFHIQTIDGEIML

Sequences:

>Translated_230_residues
MLVSKRQFLKGVGALLTGVSVYGATRTLQADSLLQPEAESETKYAMVHDENACIGCNACVQACRETNQIPEGVTRVKIER
RGPFGEYPNQSYRFSRVSCQHCEAAPCVRVCPTGAAYIDKETGIVAVNSDRCVGCQYCIAACPYQVRYIHPETRTADKCD
FCQKSRLAQGLQPACVEACPTKALTFGNLKDPESELVKLLKAKPSYRAKVDLGTRPKLFHIQTIDGEIML
>Mature_230_residues
MLVSKRQFLKGVGALLTGVSVYGATRTLQADSLLQPEAESETKYAMVHDENACIGCNACVQACRETNQIPEGVTRVKIER
RGPFGEYPNQSYRFSRVSCQHCEAAPCVRVCPTGAAYIDKETGIVAVNSDRCVGCQYCIAACPYQVRYIHPETRTADKCD
FCQKSRLAQGLQPACVEACPTKALTFGNLKDPESELVKLLKAKPSYRAKVDLGTRPKLFHIQTIDGEIML

Specific function: Probably involved in the transfer of electrons from the quinone pool to the type-c cytochromes [H]

COG id: COG0437

COG function: function code C; Fe-S-cluster-containing hydrogenase components 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Escherichia coli, GI2367345, Length=230, Percent_Identity=57.8260869565217, Blast_Score=276, Evalue=1e-75,
Organism=Escherichia coli, GI226510944, Length=220, Percent_Identity=45.4545454545455, Blast_Score=192, Evalue=1e-50,
Organism=Escherichia coli, GI1787872, Length=184, Percent_Identity=35.3260869565217, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1789370, Length=233, Percent_Identity=31.7596566523605, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1787122, Length=184, Percent_Identity=34.2391304347826, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1790326, Length=188, Percent_Identity=35.1063829787234, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1787749, Length=169, Percent_Identity=33.7278106508876, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI1787963, Length=205, Percent_Identity=27.3170731707317, Blast_Score=78, Evalue=4e-16,
Organism=Escherichia coli, GI87082179, Length=154, Percent_Identity=33.7662337662338, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1788811, Length=153, Percent_Identity=32.6797385620915, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1789067, Length=154, Percent_Identity=33.1168831168831, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1787740, Length=106, Percent_Identity=33.9622641509434, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI2367245, Length=150, Percent_Identity=34.6666666666667, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI87082180, Length=169, Percent_Identity=31.3609467455621, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1787478, Length=106, Percent_Identity=33.0188679245283, Blast_Score=70, Evalue=9e-14,
Organism=Escherichia coli, GI87082114, Length=171, Percent_Identity=28.6549707602339, Blast_Score=61, Evalue=7e-11,
Organism=Escherichia coli, GI1789079, Length=204, Percent_Identity=27.9411764705882, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR017567
- InterPro:   IPR006311 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 25317; Mature: 25317

Theoretical pI: Translated: 8.12; Mature: 8.12

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

7.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
8.3 %Cys+Met (Translated Protein)
7.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
8.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVSKRQFLKGVGALLTGVSVYGATRTLQADSLLQPEAESETKYAMVHDENACIGCNACV
CCCCHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCEEEEEECCCCEEEHHHHH
QACRETNQIPEGVTRVKIERRGPFGEYPNQSYRFSRVSCQHCEAAPCVRVCPTGAAYIDK
HHHHHHCCCCCCCEEEEEECCCCCCCCCCCCEEECCCCCCCCCCCCCEEECCCCCEEEEC
ETGIVAVNSDRCVGCQYCIAACPYQVRYIHPETRTADKCDFCQKSRLAQGLQPACVEACP
CCCEEEECCCCCCHHHHHHHHCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCHHHHHHCC
TKALTFGNLKDPESELVKLLKAKPSYRAKVDLGTRPKLFHIQTIDGEIML
CCEEECCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCEEEEEECCCCEEC
>Mature Secondary Structure
MLVSKRQFLKGVGALLTGVSVYGATRTLQADSLLQPEAESETKYAMVHDENACIGCNACV
CCCCHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCEEEEEECCCCEEEHHHHH
QACRETNQIPEGVTRVKIERRGPFGEYPNQSYRFSRVSCQHCEAAPCVRVCPTGAAYIDK
HHHHHHCCCCCCCEEEEEECCCCCCCCCCCCEEECCCCCCCCCCCCCEEECCCCCEEEEC
ETGIVAVNSDRCVGCQYCIAACPYQVRYIHPETRTADKCDFCQKSRLAQGLQPACVEACP
CCCEEEECCCCCCHHHHHHHHCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCHHHHHHCC
TKALTFGNLKDPESELVKLLKAKPSYRAKVDLGTRPKLFHIQTIDGEIML
CCEEECCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCEEEEEECCCCEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: reduced cytochrome C552; nitrite [C]

Specific reaction: reduced cytochrome C552 + nitrite = oxidized cytochrome C552 + NH3 [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]