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The map label for this gene is pntB [H]

Identifier: 119775973

GI number: 119775973

Start: 3380847

End: 3382331

Strand: Direct

Name: pntB [H]

Synonym: Sama_2841

Alternate gene names: 119775973

Gene position: 3380847-3382331 (Clockwise)

Preceding gene: 119775972

Following gene: 119775974

Centisome position: 78.51

GC content: 57.58

Gene sequence:

>1485_bases
GTGTCTCAAGGACTGGTAACAGCAGCCTACATAGTAGCAGCGCTGTGTTTTATTTTGAGTCTCGCGGGCCTGTCCCGTCA
GGAGACCGCCAAGCAGGGTAACCTCTTTGGTATCACGGGCATGGCCATTGCGCTTATTGCCACTATCCTCAACCCGGAAA
CCAGTGGTGTACACTGGATTATTCTCGCCATGGTTATCGGCGGCGCCATTGGCGTGCGTCTGGCCCTCAAGGTGGAAATG
ACCGAGATGCCGGAACTGGTGGCCATTCTCCACAGTTTTGTGGGTATGGCAGCCGTGCTGGTTGGCTTTAACAGCTTTAT
CGACGTGCATCCCCAGGCGGTCACCGAAGTGGTGATTAGCGTGGGTGGCAATATCGACCAGAGCCTCGAAGCCGCCAAGG
CCGCATTGCAGGAAGCGAGCAAGGCCGCAGAAGGTCATCACCTCACCGGCGCCATGCTCAGCATCCATCTGGTGGAAGTG
TTCCTCGGGGTCTTTATCGGTGCCGTGACTTTCACCGGCTCTGTAGTGGCCTTCTGTAAGCTGCGCGGACTGATTTCCTC
CAAGCCACTGATGCTGCCCCATCGCCATAAGCTGAACCTGCTGGCGGTACTGGTATCTTTTGGCCTGATGGTGCTCTTTG
TAAAAGCCGATGGCGCTATGCTGCCGCTTATCATCATGACACTTATCGCCTTTGCCTTTGGCTGGCATCTGGTGGCCAGC
ATCGGCGGCGCCGACATGCCGGTGGTGGTGTCCATGCTGAACTCCTACTCAGGCTGGGCGGCCGCGGCGGCGGGCTTTAT
GCTCTCCAACGACCTGCTTATCGTCACCGGTGCCCTGGTGGGCTCCTCCGGTGCCATCCTGTCTTACATCATGTGTAAGG
CGATGAACCGCTCGTTTATCTCGGTGATTGCCGGTGGTTTTGGTACCGATGGCGCTGTGTCCAGCGGTGATGAAGAAATG
GGTGAATACCGCGAAACCAACGCCGAAGATGTGGCCGACATGCTGAAAAACGCAAGCTCAGTCATCATCACCCCCGGCTA
CGGTATGGCGGTGGCTCAGGCTCAGTATCCGGTGGCCGAAATCACCCAGAAGCTGCGTGACCGTGGCATCGAAGTACGCT
TCGGTATCCACCCGGTTGCCGGTCGTCTGCCAGGCCACATGAACGTGCTGCTGGCCGAGGCCAAGGTGCCTTACGACATA
GTGCTGGAAATGGATGAAATCAACGAAGACTTCCCCGAGACGGATGTTGTGCTGGTGATTGGTGCCAACGACACAGTGAA
CCCAGCGGCCTCGGAAGACCCAGCCAGCCCCATCGCCGGTATGCCGGTGCTGGAAGTATGGAAAGCCCAAACCGTGATCG
GCTTCAAGCGTTCCATGAACACAGGCTACGCCGGGGTACAGAACCCGCTGTTCTTCCGCGATAACACCCAGATGCTGTTT
GGCGATGCCAAGGCCAGTGTCGAGGCGATTTTGAAGGCGCTGTAA

Upstream 100 bases:

>100_bases
GTTTATTGCCGTGCTCATTGCCAGTATCAACATCTTCGGCGGCTTTACCGTCACTCAGCGCATGCTGAAGATGTTCCGTA
AGGATTAAGGGGGAATCACT

Downstream 100 bases:

>100_bases
GCCTTGGATGCTTACGATAAGCATCATTGATAACCTCTGAAAAGGGCGCCATCGGGCGCCCTTTTTTATCCGCGCTCGGC
GGCAGTTTCAATTGCAATTG

Product: pyridine nucleotide transhydrogenase

Products: NA

Alternate protein names: Nicotinamide nucleotide transhydrogenase subunit beta; Pyridine nucleotide transhydrogenase subunit beta [H]

Number of amino acids: Translated: 494; Mature: 493

Protein sequence:

>494_residues
MSQGLVTAAYIVAALCFILSLAGLSRQETAKQGNLFGITGMAIALIATILNPETSGVHWIILAMVIGGAIGVRLALKVEM
TEMPELVAILHSFVGMAAVLVGFNSFIDVHPQAVTEVVISVGGNIDQSLEAAKAALQEASKAAEGHHLTGAMLSIHLVEV
FLGVFIGAVTFTGSVVAFCKLRGLISSKPLMLPHRHKLNLLAVLVSFGLMVLFVKADGAMLPLIIMTLIAFAFGWHLVAS
IGGADMPVVVSMLNSYSGWAAAAAGFMLSNDLLIVTGALVGSSGAILSYIMCKAMNRSFISVIAGGFGTDGAVSSGDEEM
GEYRETNAEDVADMLKNASSVIITPGYGMAVAQAQYPVAEITQKLRDRGIEVRFGIHPVAGRLPGHMNVLLAEAKVPYDI
VLEMDEINEDFPETDVVLVIGANDTVNPAASEDPASPIAGMPVLEVWKAQTVIGFKRSMNTGYAGVQNPLFFRDNTQMLF
GDAKASVEAILKAL

Sequences:

>Translated_494_residues
MSQGLVTAAYIVAALCFILSLAGLSRQETAKQGNLFGITGMAIALIATILNPETSGVHWIILAMVIGGAIGVRLALKVEM
TEMPELVAILHSFVGMAAVLVGFNSFIDVHPQAVTEVVISVGGNIDQSLEAAKAALQEASKAAEGHHLTGAMLSIHLVEV
FLGVFIGAVTFTGSVVAFCKLRGLISSKPLMLPHRHKLNLLAVLVSFGLMVLFVKADGAMLPLIIMTLIAFAFGWHLVAS
IGGADMPVVVSMLNSYSGWAAAAAGFMLSNDLLIVTGALVGSSGAILSYIMCKAMNRSFISVIAGGFGTDGAVSSGDEEM
GEYRETNAEDVADMLKNASSVIITPGYGMAVAQAQYPVAEITQKLRDRGIEVRFGIHPVAGRLPGHMNVLLAEAKVPYDI
VLEMDEINEDFPETDVVLVIGANDTVNPAASEDPASPIAGMPVLEVWKAQTVIGFKRSMNTGYAGVQNPLFFRDNTQMLF
GDAKASVEAILKAL
>Mature_493_residues
SQGLVTAAYIVAALCFILSLAGLSRQETAKQGNLFGITGMAIALIATILNPETSGVHWIILAMVIGGAIGVRLALKVEMT
EMPELVAILHSFVGMAAVLVGFNSFIDVHPQAVTEVVISVGGNIDQSLEAAKAALQEASKAAEGHHLTGAMLSIHLVEVF
LGVFIGAVTFTGSVVAFCKLRGLISSKPLMLPHRHKLNLLAVLVSFGLMVLFVKADGAMLPLIIMTLIAFAFGWHLVASI
GGADMPVVVSMLNSYSGWAAAAAGFMLSNDLLIVTGALVGSSGAILSYIMCKAMNRSFISVIAGGFGTDGAVSSGDEEMG
EYRETNAEDVADMLKNASSVIITPGYGMAVAQAQYPVAEITQKLRDRGIEVRFGIHPVAGRLPGHMNVLLAEAKVPYDIV
LEMDEINEDFPETDVVLVIGANDTVNPAASEDPASPIAGMPVLEVWKAQTVIGFKRSMNTGYAGVQNPLFFRDNTQMLFG
DAKASVEAILKAL

Specific function: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane [H]

COG id: COG1282

COG function: function code C; NAD/NADP transhydrogenase beta subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNT beta subunit family [H]

Homologues:

Organism=Homo sapiens, GI122939155, Length=487, Percent_Identity=48.2546201232033, Blast_Score=444, Evalue=1e-125,
Organism=Homo sapiens, GI122939153, Length=487, Percent_Identity=48.2546201232033, Blast_Score=444, Evalue=1e-125,
Organism=Escherichia coli, GI1787886, Length=500, Percent_Identity=74.4, Blast_Score=728, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17550456, Length=493, Percent_Identity=48.6815415821501, Blast_Score=415, Evalue=1e-116,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012136
- InterPro:   IPR004003 [H]

Pfam domain/function: PF02233 PNTB [H]

EC number: =1.6.1.2 [H]

Molecular weight: Translated: 51991; Mature: 51859

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQGLVTAAYIVAALCFILSLAGLSRQETAKQGNLFGITGMAIALIATILNPETSGVHWI
CCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCEEEHHHHHHHHHHHHHCCCCCCHHHH
ILAMVIGGAIGVRLALKVEMTEMPELVAILHSFVGMAAVLVGFNSFIDVHPQAVTEVVIS
HHHHHHHHHHHEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
VGGNIDQSLEAAKAALQEASKAAEGHHLTGAMLSIHLVEVFLGVFIGAVTFTGSVVAFCK
HCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRGLISSKPLMLPHRHKLNLLAVLVSFGLMVLFVKADGAMLPLIIMTLIAFAFGWHLVAS
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
IGGADMPVVVSMLNSYSGWAAAAAGFMLSNDLLIVTGALVGSSGAILSYIMCKAMNRSFI
CCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCEEEEEEHHHCCCCHHHHHHHHHHHCHHHH
SVIAGGFGTDGAVSSGDEEMGEYRETNAEDVADMLKNASSVIITPGYGMAVAQAQYPVAE
HHHHCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHCCCCEEEECCCCCCHHHCCCCHHH
ITQKLRDRGIEVRFGIHPVAGRLPGHMNVLLAEAKVPYDIVLEMDEINEDFPETDVVLVI
HHHHHHHCCCEEEECCCHHCCCCCCCCEEEEECCCCCEEEEEEHHHCCCCCCCCCEEEEE
GANDTVNPAASEDPASPIAGMPVLEVWKAQTVIGFKRSMNTGYAGVQNPLFFRDNTQMLF
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCEEEE
GDAKASVEAILKAL
CCHHHHHHHHHHHC
>Mature Secondary Structure 
SQGLVTAAYIVAALCFILSLAGLSRQETAKQGNLFGITGMAIALIATILNPETSGVHWI
CCCHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCEEEHHHHHHHHHHHHHCCCCCCHHHH
ILAMVIGGAIGVRLALKVEMTEMPELVAILHSFVGMAAVLVGFNSFIDVHPQAVTEVVIS
HHHHHHHHHHHEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
VGGNIDQSLEAAKAALQEASKAAEGHHLTGAMLSIHLVEVFLGVFIGAVTFTGSVVAFCK
HCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRGLISSKPLMLPHRHKLNLLAVLVSFGLMVLFVKADGAMLPLIIMTLIAFAFGWHLVAS
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
IGGADMPVVVSMLNSYSGWAAAAAGFMLSNDLLIVTGALVGSSGAILSYIMCKAMNRSFI
CCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCEEEEEEHHHCCCCHHHHHHHHHHHCHHHH
SVIAGGFGTDGAVSSGDEEMGEYRETNAEDVADMLKNASSVIITPGYGMAVAQAQYPVAE
HHHHCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHCCCCEEEECCCCCCHHHCCCCHHH
ITQKLRDRGIEVRFGIHPVAGRLPGHMNVLLAEAKVPYDIVLEMDEINEDFPETDVVLVI
HHHHHHHCCCEEEECCCHHCCCCCCCCEEEEECCCCCEEEEEEHHHCCCCCCCCCEEEEE
GANDTVNPAASEDPASPIAGMPVLEVWKAQTVIGFKRSMNTGYAGVQNPLFFRDNTQMLF
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCEEEE
GDAKASVEAILKAL
CCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]