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The map label for this gene is yybE [H]

Identifier: 119775929

GI number: 119775929

Start: 3337461

End: 3338297

Strand: Direct

Name: yybE [H]

Synonym: Sama_2797

Alternate gene names: 119775929

Gene position: 3337461-3338297 (Clockwise)

Preceding gene: 119775925

Following gene: 119775930

Centisome position: 77.5

GC content: 55.91

Gene sequence:

>837_bases
ATGAACCTTAAGGCATTGAATTACTTCGTCGCAGTCTTGGAAAGAGGCAGTATCAGCGCCGCCGCCAAGCATTGCTACAT
AGCACAGCCCTCGATTTCGGCAGCCATTGGCGCCCTGGAGTCTGAACTGGGCGTGCAGCTTTTTGCCCGGCACGGGAAAG
GGGTATCGGCCACCGATGCGGGCATGCGTTTGTATCCTCTGGCCAAACGGCTCCTGAACGAATCCAAGGCCATTCAGTCG
CTGTTTTCCAAGCCAGAAACCCAGGTGCCATTCAGACTGGGGCTTATCCGCTCGCTGGGGGTTTCACGCATGAGTATGCT
GCTCAAAGACTTTACCGCGGCCTGCCCTGACATGGATTTAACCCTGGTTGAGCCGAGCGAAGAGTGCGACGGCCGCATCA
TTACCACCGCCGATTTAACACCCAACGAAAGCTTTCAGGCCATGTGGCACGATACGTATTTGCTGGCCATTCCTCCGGCA
TTGAGTCTGGCGCTGAAAAGCAGCATCCGACTGGAAGATTTACAGGGACAACCTTTTATTCACAGAGCCCCCTGCGAGGC
ACTCACCAGCCTGCAGCAACTTTTGGACATGGAAGGGATAAAGATGCAGGTGCGGGCCCGTATTCAGACCATAGAATATG
CGGTGGGATTGGTTGCGGCAGGATTAGGCATTGCCTTGGTGCCCGCCATTCCGGCATTGCTGGACCAGCAGGACATAGTG
TTTCGGCCACTGGCAGACATAGATCTTAAACGTACCGTGGGGCTGGCGCTACCTCTGGGGCACCCTCCCACGCCTCAGCA
GCGACAACTGGTCGCCCTTTGCCGACAATGTCACTAA

Upstream 100 bases:

>100_bases
CTTGTGATTTGCACTAGCATAGGCATAATCGATCATTAGGAAAAATATTCTTTTTCTCTCACTCCCATAGTATTTTCCTA
TACCTTACGCGAAGGGAAAG

Downstream 100 bases:

>100_bases
TGCCGCCTGACCTTTCGCGCTGCGTATTGGGCAAAGTACAAGTATCAAATTGCAACAGTGAAACCTTGGCCACTGCTGCA
CCGACATTTACATGCTAATC

Product: regulatory protein, LysR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 278; Mature: 278

Protein sequence:

>278_residues
MNLKALNYFVAVLERGSISAAAKHCYIAQPSISAAIGALESELGVQLFARHGKGVSATDAGMRLYPLAKRLLNESKAIQS
LFSKPETQVPFRLGLIRSLGVSRMSMLLKDFTAACPDMDLTLVEPSEECDGRIITTADLTPNESFQAMWHDTYLLAIPPA
LSLALKSSIRLEDLQGQPFIHRAPCEALTSLQQLLDMEGIKMQVRARIQTIEYAVGLVAAGLGIALVPAIPALLDQQDIV
FRPLADIDLKRTVGLALPLGHPPTPQQRQLVALCRQCH

Sequences:

>Translated_278_residues
MNLKALNYFVAVLERGSISAAAKHCYIAQPSISAAIGALESELGVQLFARHGKGVSATDAGMRLYPLAKRLLNESKAIQS
LFSKPETQVPFRLGLIRSLGVSRMSMLLKDFTAACPDMDLTLVEPSEECDGRIITTADLTPNESFQAMWHDTYLLAIPPA
LSLALKSSIRLEDLQGQPFIHRAPCEALTSLQQLLDMEGIKMQVRARIQTIEYAVGLVAAGLGIALVPAIPALLDQQDIV
FRPLADIDLKRTVGLALPLGHPPTPQQRQLVALCRQCH
>Mature_278_residues
MNLKALNYFVAVLERGSISAAAKHCYIAQPSISAAIGALESELGVQLFARHGKGVSATDAGMRLYPLAKRLLNESKAIQS
LFSKPETQVPFRLGLIRSLGVSRMSMLLKDFTAACPDMDLTLVEPSEECDGRIITTADLTPNESFQAMWHDTYLLAIPPA
LSLALKSSIRLEDLQGQPFIHRAPCEALTSLQQLLDMEGIKMQVRARIQTIEYAVGLVAAGLGIALVPAIPALLDQQDIV
FRPLADIDLKRTVGLALPLGHPPTPQQRQLVALCRQCH

Specific function: Hydrogen Peroxide Sensor. Activates The Expression Of A Regulon Of Hydrogen Peroxide-Inducible Genes Such As Katg, Gor, Ahpc, Ahpf, Oxys (A Regulatory RNA), Dps, Fur And Grxa. Oxyr Expression Is Negatively Autoregulated By Binding To A 43 Bp Region Upstre

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=290, Percent_Identity=27.2413793103448, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI2367136, Length=257, Percent_Identity=27.2373540856031, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1789204, Length=285, Percent_Identity=28.0701754385965, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787879, Length=296, Percent_Identity=25.3378378378378, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI145693105, Length=271, Percent_Identity=26.5682656826568, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI157672245, Length=159, Percent_Identity=33.3333333333333, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1788297, Length=131, Percent_Identity=34.3511450381679, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787601, Length=126, Percent_Identity=30.952380952381, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787530, Length=267, Percent_Identity=23.5955056179775, Blast_Score=61, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 30244; Mature: 30244

Theoretical pI: Translated: 7.47; Mature: 7.47

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLKALNYFVAVLERGSISAAAKHCYIAQPSISAAIGALESELGVQLFARHGKGVSATDA
CCCHHHHHHHHHHHCCCHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
GMRLYPLAKRLLNESKAIQSLFSKPETQVPFRLGLIRSLGVSRMSMLLKDFTAACPDMDL
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
TLVEPSEECDGRIITTADLTPNESFQAMWHDTYLLAIPPALSLALKSSIRLEDLQGQPFI
EEECCCHHHCCEEEEEECCCCCCCHHHHHHCEEEEEECHHHHHHHHHCCCEECCCCCCCE
HRAPCEALTSLQQLLDMEGIKMQVRARIQTIEYAVGLVAAGLGIALVPAIPALLDQQDIV
ECCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
FRPLADIDLKRTVGLALPLGHPPTPQQRQLVALCRQCH
ECCCCCCCHHHHHCEEEECCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MNLKALNYFVAVLERGSISAAAKHCYIAQPSISAAIGALESELGVQLFARHGKGVSATDA
CCCHHHHHHHHHHHCCCHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
GMRLYPLAKRLLNESKAIQSLFSKPETQVPFRLGLIRSLGVSRMSMLLKDFTAACPDMDL
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
TLVEPSEECDGRIITTADLTPNESFQAMWHDTYLLAIPPALSLALKSSIRLEDLQGQPFI
EEECCCHHHCCEEEEEECCCCCCCHHHHHHCEEEEEECHHHHHHHHHCCCEECCCCCCCE
HRAPCEALTSLQQLLDMEGIKMQVRARIQTIEYAVGLVAAGLGIALVPAIPALLDQQDIV
ECCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
FRPLADIDLKRTVGLALPLGHPPTPQQRQLVALCRQCH
ECCCCCCCHHHHHCEEEECCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]