Click here to switch to the map view.

The map label for this gene is rpiA [H]

Identifier: 119775868

GI number: 119775868

Start: 3269321

End: 3269980

Strand: Direct

Name: rpiA [H]

Synonym: Sama_2736

Alternate gene names: 119775868

Gene position: 3269321-3269980 (Clockwise)

Preceding gene: 119775863

Following gene: 119775873

Centisome position: 75.92

GC content: 55.15

Gene sequence:

>660_bases
ATGACTCAAGACGAAATGAAAAAGGCCGCCGCCTGGGCTGCACTCAAATACGTAGAAAAAGACAGTATTGTTGGCGTGGG
CACAGGCTCTACTGTGAACCACTTTATCGACGCACTGGGCACCATCAAGGCGGATATCGAAGGCGCTGTGTCGTCTTCTG
AGGCCTCCACCGCCAAGCTCAAGGCGTTGGGCATTCCGGTTTACGACTTAAACAGTGTCGACAGACTGTCTGTTTATGTG
GACGGAGCGGATGAAATCAACGGCCAGATGGACATGATCAAGGGCGGCGGCGCGGCCCTCACCCGTGAAAAAATTGTCGC
TGCCGTGGCCGATAAATTTATCTGTATCGTGGACAACACCAAAGAAGTGGCCATCCTAGGTGAGTTTCCGCTGCCGGTTG
AAGTCATCCCCATGGCCCGCTCCTACGTGGCCCGTGAGCTGGTCAAACTGGGCGGTGACCCTGTGTACCGCGAAGGCGTT
GTTACCGACAACGGCAACGTTATTCTGGATGTGCACAACATGAAGATCATGGAACCCAAGAAGCTCGAAGCACAAATCAA
CGGCATCGTGGGTGTGGTTACCAATGGCCTGTTCGCCCACCGCGGCGCTGATGTGCTCTTGGTCGGCACCCCCGATGGCG
TAAAAACGGTTACCGCCTGA

Upstream 100 bases:

>100_bases
GCGCAGGCAGGATTTTTGTTAGCCAACAACCACTTTTATGGCCACTTGCAGGTATAATAAGGGCAATTTTTTTGCATTAA
GTCGTTTACAGGACCTCACC

Downstream 100 bases:

>100_bases
TAAGCTAACCGTTAAAAACAAAAAGCCACCCAAGGGTGGCTTTTTTGTTAACAGGCTCGTGGTTAACGGGTGTCCGGACT
CATTTGGCGTCGATTTGCTC

Product: ribose-5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI [H]

Number of amino acids: Translated: 219; Mature: 218

Protein sequence:

>219_residues
MTQDEMKKAAAWAALKYVEKDSIVGVGTGSTVNHFIDALGTIKADIEGAVSSSEASTAKLKALGIPVYDLNSVDRLSVYV
DGADEINGQMDMIKGGGAALTREKIVAAVADKFICIVDNTKEVAILGEFPLPVEVIPMARSYVARELVKLGGDPVYREGV
VTDNGNVILDVHNMKIMEPKKLEAQINGIVGVVTNGLFAHRGADVLLVGTPDGVKTVTA

Sequences:

>Translated_219_residues
MTQDEMKKAAAWAALKYVEKDSIVGVGTGSTVNHFIDALGTIKADIEGAVSSSEASTAKLKALGIPVYDLNSVDRLSVYV
DGADEINGQMDMIKGGGAALTREKIVAAVADKFICIVDNTKEVAILGEFPLPVEVIPMARSYVARELVKLGGDPVYREGV
VTDNGNVILDVHNMKIMEPKKLEAQINGIVGVVTNGLFAHRGADVLLVGTPDGVKTVTA
>Mature_218_residues
TQDEMKKAAAWAALKYVEKDSIVGVGTGSTVNHFIDALGTIKADIEGAVSSSEASTAKLKALGIPVYDLNSVDRLSVYVD
GADEINGQMDMIKGGGAALTREKIVAAVADKFICIVDNTKEVAILGEFPLPVEVIPMARSYVARELVKLGGDPVYREGVV
TDNGNVILDVHNMKIMEPKKLEAQINGIVGVVTNGLFAHRGADVLLVGTPDGVKTVTA

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI94536842, Length=224, Percent_Identity=35.7142857142857, Blast_Score=105, Evalue=4e-23,
Organism=Escherichia coli, GI1789280, Length=217, Percent_Identity=75.1152073732719, Blast_Score=332, Evalue=1e-92,
Organism=Caenorhabditis elegans, GI17551758, Length=214, Percent_Identity=36.9158878504673, Blast_Score=110, Evalue=5e-25,
Organism=Saccharomyces cerevisiae, GI6324669, Length=245, Percent_Identity=32.2448979591837, Blast_Score=90, Evalue=3e-19,
Organism=Drosophila melanogaster, GI281364072, Length=208, Percent_Identity=33.1730769230769, Blast_Score=82, Evalue=2e-16,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004788
- InterPro:   IPR020672 [H]

Pfam domain/function: PF06026 Rib_5-P_isom_A [H]

EC number: =5.3.1.6 [H]

Molecular weight: Translated: 23095; Mature: 22964

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQDEMKKAAAWAALKYVEKDSIVGVGTGSTVNHFIDALGTIKADIEGAVSSSEASTAKL
CCHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEE
KALGIPVYDLNSVDRLSVYVDGADEINGQMDMIKGGGAALTREKIVAAVADKFICIVDNT
EEECCCEEECCCCCEEEEEECCHHHCCCEEEEEECCCCHHHHHHHHHHHHCCEEEEEECC
KEVAILGEFPLPVEVIPMARSYVARELVKLGGDPVYREGVVTDNGNVILDVHNMKIMEPK
CEEEEEECCCCCEEEEHHHHHHHHHHHHHHCCCCCEECCEEECCCCEEEEECCEEEECCH
KLEAQINGIVGVVTNGLFAHRGADVLLVGTPDGVKTVTA
HHHHHHCCEEEEECCCEEEECCCCEEEEECCCCCEECCC
>Mature Secondary Structure 
TQDEMKKAAAWAALKYVEKDSIVGVGTGSTVNHFIDALGTIKADIEGAVSSSEASTAKL
CHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEE
KALGIPVYDLNSVDRLSVYVDGADEINGQMDMIKGGGAALTREKIVAAVADKFICIVDNT
EEECCCEEECCCCCEEEEEECCHHHCCCEEEEEECCCCHHHHHHHHHHHHCCEEEEEECC
KEVAILGEFPLPVEVIPMARSYVARELVKLGGDPVYREGVVTDNGNVILDVHNMKIMEPK
CEEEEEECCCCCEEEEHHHHHHHHHHHHHHCCCCCEECCEEECCCCEEEEECCEEEECCH
KLEAQINGIVGVVTNGLFAHRGADVLLVGTPDGVKTVTA
HHHHHHCCEEEEECCCEEEECCCCEEEEECCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA