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The map label for this gene is hlyB [H]

Identifier: 119775767

GI number: 119775767

Start: 3155682

End: 3157802

Strand: Reverse

Name: hlyB [H]

Synonym: Sama_2635

Alternate gene names: 119775767

Gene position: 3157802-3155682 (Counterclockwise)

Preceding gene: 119775768

Following gene: 119775765

Centisome position: 73.33

GC content: 54.69

Gene sequence:

>2121_bases
ATGAAACATCTTCCCCTGCGACAAAAGCTACTTTGGATGACCTCGGCGCTGTTTCTGGCCACTGTGGCCACCATGTCGAT
TACCCTCTGGAGTACCCTCAATAACAAAACCGACGAGCTCTTCGTTGAGGTCGACACAGCGCTGAATGATGAAATACGAA
CCAAATTGACTGCCAGCGCCGGGCGCTATGGTGAAAAGGTCGCGGCCTTTATCAACGAGGCCTACCGTATCCCCTATTCC
TTCAGTGCCATGATGGAAAACGATGCGCTGGTCGGACGGATGAATCGTGAAACCGTTCAGGATGCCGTGGGCGCTGTGCT
GCAGAAAAATCGCCAGATTTCCTCCATGTATGCACAGTTCGAACCCAATGGTTTCGATGGCCGAGACAGTGAATTTACGG
CACCCGGTCTGATGCACTCGGTTGAGGGCGTGGGAACGCTCGAGGTGTACTTTTATCGCAACGATGATGGCAGTCAGACC
CAGTCTCAGGTGGATGATGCCAATGAAAAATACGCCGATACCCTCAACGAATTTGGTCTGCGGGAAGCTGAGTGGTATCT
GTGTGCCAAAGACACCCAAAAACCCTGCCTGATGGAGCCCTATCTCTACGAAATCACCCCCGGCAACAACATGCTGATGA
CTTCATTGACCGTACCCATTGTTCGGGGTGGCCGTTTTCGCGGTGTGGTCGGTGTGGATTTGAACCTGCCCGTGTTTCAA
AAAATGATTGAGGAATTGTCGGCAAGTCTCTATCAGGGCCAGGCCAAGGTGACCTTGCTGTCCACCAAGGGGCTGATTGT
GGCCGCGAGCCACTATGACAAAAAAGCCAGGCCGCTCGGAGAGGCAATCGACAAGTCTCTCGCCAACCAAATTCTGGGTC
TGGGCAAGGGAGATGGTTACCTGCTTAACGACAGCAGCATGATAGTGGCCTATCCCATCAATATTCCGCTCTCTGGCAGT
CAGTGGCTGCTTGCTATCGAAGTGCCAAGGCAGATAGCGTTGGCCAGTGCTGAACAGGTTGAGGGGAGCATGCAGGCCAT
GGCAGCCAGCCTGGGGCGCTTTGTGTTGCTGCTGGGTATTGGTATTGCCGCTGTGGCTGTGATTCTTATCGCTCTTTTTA
TTCGCAGCGTGGTGGCGCCTATCCAGCAAATTCAGCAGCGGGTCAGTCAGTTGGCCAGTGCTGAGGGGGATTTAACCCAA
AGCCTGAAAGTGGATGAACACGCAGAGCTGATTGCCCTGGGCAATGGGTTTAATGCGTTTATCGGTAAGCTTCACGGACT
TATCAGTGAATTGAAAAAGGTCGCAACAGAATCCCGCAATGAAAGCCAGGCAACGGCCCGGATTGCCGAGGAAACCAAGC
AAAGTGTTAATCGGCAATACAGTGAAATCGAGAGTGTGGTGACCGCCGTTAATGAGATGAGCCATACCGCCCATGAAGTG
GCTAAGGCATCTGAGCAAACGGCCAGCGAGTCGGCCGCCATGGCCTCGCAGGTTAAGGTGAGTCAGGACAGTTTGACTCA
GGCGGTTTCTCTTGTGAGCACCATGTCCAAGGAGTCGCTGCAAGCCAAGATAGCGGTGGGCAAGGTGGCAGAAAGCAGCA
CCAATATCAGCAAAATATTGGAAGTGATCAGTGCCATTGCAGCCCAGACAAACCTGCTGGCGCTCAACGCGGCCATCGAA
GCGGCCCGCGCCGGAGAGCAGGGCAGGGGCTTTGCTGTGGTGGCCGATGAAGTGCGTTCACTTGCCTCCAAAACCCAGGC
TTCCACCGATGATATCAGTCGGCTTATCGATGCGTTGGAACAGGAAGTGAAAGGGGCTTCCGGGATTATCGATAAAGGGG
TCGGCCTTGCTGAGCAGGCGGTGGCGCAAACCGAGCAGGCGTTTGAGGCTCTGTCGGTGATGGTGGCGGGTATCAATGAA
ATCTCCAATCAGGTGACCCAAATTGCCACGGCTGCGGAGGAACAAAGTGCCGTCACCGAAGAGGTGAGCCGCAACATCAC
GGGGATCTCAGACTCGGCGGCAGAGCTGATGGATTTGGCCGGTAAGGCGCGGGAGAGCAGTGAAAGCCTGGCCAAGTTGG
TTGGCAGGCAGGAGAGTCAGCTGGCCAAGCTGCGCACCTGA

Upstream 100 bases:

>100_bases
GGCCGCCTTTTTGCTGCAAAAAAAGCACGGACGCAGATAGAGACTATACTCAGTCATACGTTAGTCTACCTATGTGTTTT
CAGGATCTTGCGGAGAGTGC

Downstream 100 bases:

>100_bases
ATAATGCTAAACCTGATAAAAAGGCTGCCTATGGCAGCCTTTTTATCTACTGGGTATTAAACGCTGTCCAGAGGTTCCAG
GCTGACATCTGTTAATGGCG

Product: putative methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 706; Mature: 706

Protein sequence:

>706_residues
MKHLPLRQKLLWMTSALFLATVATMSITLWSTLNNKTDELFVEVDTALNDEIRTKLTASAGRYGEKVAAFINEAYRIPYS
FSAMMENDALVGRMNRETVQDAVGAVLQKNRQISSMYAQFEPNGFDGRDSEFTAPGLMHSVEGVGTLEVYFYRNDDGSQT
QSQVDDANEKYADTLNEFGLREAEWYLCAKDTQKPCLMEPYLYEITPGNNMLMTSLTVPIVRGGRFRGVVGVDLNLPVFQ
KMIEELSASLYQGQAKVTLLSTKGLIVAASHYDKKARPLGEAIDKSLANQILGLGKGDGYLLNDSSMIVAYPINIPLSGS
QWLLAIEVPRQIALASAEQVEGSMQAMAASLGRFVLLLGIGIAAVAVILIALFIRSVVAPIQQIQQRVSQLASAEGDLTQ
SLKVDEHAELIALGNGFNAFIGKLHGLISELKKVATESRNESQATARIAEETKQSVNRQYSEIESVVTAVNEMSHTAHEV
AKASEQTASESAAMASQVKVSQDSLTQAVSLVSTMSKESLQAKIAVGKVAESSTNISKILEVISAIAAQTNLLALNAAIE
AARAGEQGRGFAVVADEVRSLASKTQASTDDISRLIDALEQEVKGASGIIDKGVGLAEQAVAQTEQAFEALSVMVAGINE
ISNQVTQIATAAEEQSAVTEEVSRNITGISDSAAELMDLAGKARESSESLAKLVGRQESQLAKLRT

Sequences:

>Translated_706_residues
MKHLPLRQKLLWMTSALFLATVATMSITLWSTLNNKTDELFVEVDTALNDEIRTKLTASAGRYGEKVAAFINEAYRIPYS
FSAMMENDALVGRMNRETVQDAVGAVLQKNRQISSMYAQFEPNGFDGRDSEFTAPGLMHSVEGVGTLEVYFYRNDDGSQT
QSQVDDANEKYADTLNEFGLREAEWYLCAKDTQKPCLMEPYLYEITPGNNMLMTSLTVPIVRGGRFRGVVGVDLNLPVFQ
KMIEELSASLYQGQAKVTLLSTKGLIVAASHYDKKARPLGEAIDKSLANQILGLGKGDGYLLNDSSMIVAYPINIPLSGS
QWLLAIEVPRQIALASAEQVEGSMQAMAASLGRFVLLLGIGIAAVAVILIALFIRSVVAPIQQIQQRVSQLASAEGDLTQ
SLKVDEHAELIALGNGFNAFIGKLHGLISELKKVATESRNESQATARIAEETKQSVNRQYSEIESVVTAVNEMSHTAHEV
AKASEQTASESAAMASQVKVSQDSLTQAVSLVSTMSKESLQAKIAVGKVAESSTNISKILEVISAIAAQTNLLALNAAIE
AARAGEQGRGFAVVADEVRSLASKTQASTDDISRLIDALEQEVKGASGIIDKGVGLAEQAVAQTEQAFEALSVMVAGINE
ISNQVTQIATAAEEQSAVTEEVSRNITGISDSAAELMDLAGKARESSESLAKLVGRQESQLAKLRT
>Mature_706_residues
MKHLPLRQKLLWMTSALFLATVATMSITLWSTLNNKTDELFVEVDTALNDEIRTKLTASAGRYGEKVAAFINEAYRIPYS
FSAMMENDALVGRMNRETVQDAVGAVLQKNRQISSMYAQFEPNGFDGRDSEFTAPGLMHSVEGVGTLEVYFYRNDDGSQT
QSQVDDANEKYADTLNEFGLREAEWYLCAKDTQKPCLMEPYLYEITPGNNMLMTSLTVPIVRGGRFRGVVGVDLNLPVFQ
KMIEELSASLYQGQAKVTLLSTKGLIVAASHYDKKARPLGEAIDKSLANQILGLGKGDGYLLNDSSMIVAYPINIPLSGS
QWLLAIEVPRQIALASAEQVEGSMQAMAASLGRFVLLLGIGIAAVAVILIALFIRSVVAPIQQIQQRVSQLASAEGDLTQ
SLKVDEHAELIALGNGFNAFIGKLHGLISELKKVATESRNESQATARIAEETKQSVNRQYSEIESVVTAVNEMSHTAHEV
AKASEQTASESAAMASQVKVSQDSLTQAVSLVSTMSKESLQAKIAVGKVAESSTNISKILEVISAIAAQTNLLALNAAIE
AARAGEQGRGFAVVADEVRSLASKTQASTDDISRLIDALEQEVKGASGIIDKGVGLAEQAVAQTEQAFEALSVMVAGINE
ISNQVTQIATAAEEQSAVTEEVSRNITGISDSAAELMDLAGKARESSESLAKLVGRQESQLAKLRT

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=316, Percent_Identity=31.3291139240506, Blast_Score=114, Evalue=3e-26,
Organism=Escherichia coli, GI1787690, Length=332, Percent_Identity=32.2289156626506, Blast_Score=110, Evalue=4e-25,
Organism=Escherichia coli, GI1789453, Length=308, Percent_Identity=29.5454545454545, Blast_Score=106, Evalue=6e-24,
Organism=Escherichia coli, GI1788195, Length=296, Percent_Identity=28.7162162162162, Blast_Score=102, Evalue=9e-23,
Organism=Escherichia coli, GI1788194, Length=351, Percent_Identity=27.0655270655271, Blast_Score=94, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 75900; Mature: 75900

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHLPLRQKLLWMTSALFLATVATMSITLWSTLNNKTDELFVEVDTALNDEIRTKLTASA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHC
GRYGEKVAAFINEAYRIPYSFSAMMENDALVGRMNRETVQDAVGAVLQKNRQISSMYAQF
CHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHC
EPNGFDGRDSEFTAPGLMHSVEGVGTLEVYFYRNDDGSQTQSQVDDANEKYADTLNEFGL
CCCCCCCCCCCCCCCHHHHHHCCCEEEEEEEEECCCCCHHHHHHHCCHHHHHHHHHHCCC
REAEWYLCAKDTQKPCLMEPYLYEITPGNNMLMTSLTVPIVRGGRFRGVVGVDLNLPVFQ
CCCCEEEEECCCCCCCCCCCEEEEECCCCCEEEEEEEHHHCCCCCCCEEEEECCCCHHHH
KMIEELSASLYQGQAKVTLLSTKGLIVAASHYDKKARPLGEAIDKSLANQILGLGKGDGY
HHHHHHHHHHHCCCEEEEEEEECCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCE
LLNDSSMIVAYPINIPLSGSQWLLAIEVPRQIALASAEQVEGSMQAMAASLGRFVLLLGI
EECCCCEEEEEEECCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GIAAVAVILIALFIRSVVAPIQQIQQRVSQLASAEGDLTQSLKVDEHAELIALGNGFNAF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCEEEECCCHHHH
IGKLHGLISELKKVATESRNESQATARIAEETKQSVNRQYSEIESVVTAVNEMSHTAHEV
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKASEQTASESAAMASQVKVSQDSLTQAVSLVSTMSKESLQAKIAVGKVAESSTNISKIL
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
EVISAIAAQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLASKTQASTDDISRLIDALE
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHCCCHHHHHHHHHHHH
QEVKGASGIIDKGVGLAEQAVAQTEQAFEALSVMVAGINEISNQVTQIATAAEEQSAVTE
HHHCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVSRNITGISDSAAELMDLAGKARESSESLAKLVGRQESQLAKLRT
HHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHCCC
>Mature Secondary Structure
MKHLPLRQKLLWMTSALFLATVATMSITLWSTLNNKTDELFVEVDTALNDEIRTKLTASA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHC
GRYGEKVAAFINEAYRIPYSFSAMMENDALVGRMNRETVQDAVGAVLQKNRQISSMYAQF
CHHHHHHHHHHHHHHCCCCHHHHHHCCCHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHC
EPNGFDGRDSEFTAPGLMHSVEGVGTLEVYFYRNDDGSQTQSQVDDANEKYADTLNEFGL
CCCCCCCCCCCCCCCHHHHHHCCCEEEEEEEEECCCCCHHHHHHHCCHHHHHHHHHHCCC
REAEWYLCAKDTQKPCLMEPYLYEITPGNNMLMTSLTVPIVRGGRFRGVVGVDLNLPVFQ
CCCCEEEEECCCCCCCCCCCEEEEECCCCCEEEEEEEHHHCCCCCCCEEEEECCCCHHHH
KMIEELSASLYQGQAKVTLLSTKGLIVAASHYDKKARPLGEAIDKSLANQILGLGKGDGY
HHHHHHHHHHHCCCEEEEEEEECCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCE
LLNDSSMIVAYPINIPLSGSQWLLAIEVPRQIALASAEQVEGSMQAMAASLGRFVLLLGI
EECCCCEEEEEEECCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GIAAVAVILIALFIRSVVAPIQQIQQRVSQLASAEGDLTQSLKVDEHAELIALGNGFNAF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCEEEECCCHHHH
IGKLHGLISELKKVATESRNESQATARIAEETKQSVNRQYSEIESVVTAVNEMSHTAHEV
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKASEQTASESAAMASQVKVSQDSLTQAVSLVSTMSKESLQAKIAVGKVAESSTNISKIL
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
EVISAIAAQTNLLALNAAIEAARAGEQGRGFAVVADEVRSLASKTQASTDDISRLIDALE
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHCCCHHHHHHHHHHHH
QEVKGASGIIDKGVGLAEQAVAQTEQAFEALSVMVAGINEISNQVTQIATAAEEQSAVTE
HHHCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EVSRNITGISDSAAELMDLAGKARESSESLAKLVGRQESQLAKLRT
HHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]