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The map label for this gene is corC [H]

Identifier: 119775710

GI number: 119775710

Start: 3085101

End: 3085979

Strand: Direct

Name: corC [H]

Synonym: Sama_2578

Alternate gene names: 119775710

Gene position: 3085101-3085979 (Clockwise)

Preceding gene: 119775709

Following gene: 119775711

Centisome position: 71.64

GC content: 52.1

Gene sequence:

>879_bases
ATGAGTGACGACATACCCCCGAGTAGCAACGCCCAAAAGAAAGGCTGGTTAGAACGCGTTAGTCAGTTATTCCAGGGCGA
ACCTCAAAATCGTGACGATCTGGTGGAAGTGATCCACGATGCCGAGCAACGCGACCTCATCACCGAAGACACCCGTGAAA
TGATCCAGGGTGTACTGGAAGTCTCAGACCTGCGTGTCAGGGACATCATGATCCCCCGCGCCCAGATTGTGGCCATTAAA
ATCGACAGCACAGTGGAAGAACTGTTGGCTACCGTCATAGGGTCGGCCCATTCACGCTTCCCCGTAGTTAACGACGATAA
AGACCACATCGAAGGCATACTGCTGGCCAAGGATCTGATCAAGTACGGATTTAATAACAGTGATGAACCCTTTGCGCTGG
AGAAGGTGATCCGCCCTGCCGTGGTGGTGCCCGAAAGCAAGCGCGTGGATGTGCTACTCAAGGAGTTTCGCTCCCAACGT
TACCATATGGCCATTGTCGTGGATGAATACGGCGGTGTATCCGGTCTGGTAACCATCGAGGATATTCTCGAAGAAATCGT
GGGTGAAATCGAAGATGAATTCGACCATGACAGTGTGGAAGAGACCGAAATCCGCAAGGTCAACAACACTGTGTTTATGG
TCAAGGCGCTGACGGCGATTGAAGACTTCAACGAAGAATTCGGTACCGACTTCTCCGACGAAGAATTTGATACTGTTGGC
GGTATGGTGGCCCACGCCTTTGGCCATCTGCCCGAACGTAATGAACAAATCAGTATCGGCGGCATCGAGTTCAAAGTGAT
CAGTGCCGACACACGGCGTCTTATTCAGCTGAGGGTCAAGTTTCCCGACCCGGAGCAGGCTGAGATAGCCGAGATCTGA

Upstream 100 bases:

>100_bases
AGAAATGGAAGCGCTGGAAACCACGCTTCTGACTGGCCTTGGTTACCCCGATCCCTATAAGGAGCAATAATCGGCCCTTT
ATTGAGCCGTGAAAATCACT

Downstream 100 bases:

>100_bases
GTTTCCCCTGAACGGGCCTTCACGGCCCGTTTTTTCCTGTCTATGGATGATTGACTGCAATTGGACTTGAATGCAATCGC
CGGCCGCCGCTGGCCCCGAC

Product: magnesium and cobalt efflux protein CorC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MSDDIPPSSNAQKKGWLERVSQLFQGEPQNRDDLVEVIHDAEQRDLITEDTREMIQGVLEVSDLRVRDIMIPRAQIVAIK
IDSTVEELLATVIGSAHSRFPVVNDDKDHIEGILLAKDLIKYGFNNSDEPFALEKVIRPAVVVPESKRVDVLLKEFRSQR
YHMAIVVDEYGGVSGLVTIEDILEEIVGEIEDEFDHDSVEETEIRKVNNTVFMVKALTAIEDFNEEFGTDFSDEEFDTVG
GMVAHAFGHLPERNEQISIGGIEFKVISADTRRLIQLRVKFPDPEQAEIAEI

Sequences:

>Translated_292_residues
MSDDIPPSSNAQKKGWLERVSQLFQGEPQNRDDLVEVIHDAEQRDLITEDTREMIQGVLEVSDLRVRDIMIPRAQIVAIK
IDSTVEELLATVIGSAHSRFPVVNDDKDHIEGILLAKDLIKYGFNNSDEPFALEKVIRPAVVVPESKRVDVLLKEFRSQR
YHMAIVVDEYGGVSGLVTIEDILEEIVGEIEDEFDHDSVEETEIRKVNNTVFMVKALTAIEDFNEEFGTDFSDEEFDTVG
GMVAHAFGHLPERNEQISIGGIEFKVISADTRRLIQLRVKFPDPEQAEIAEI
>Mature_291_residues
SDDIPPSSNAQKKGWLERVSQLFQGEPQNRDDLVEVIHDAEQRDLITEDTREMIQGVLEVSDLRVRDIMIPRAQIVAIKI
DSTVEELLATVIGSAHSRFPVVNDDKDHIEGILLAKDLIKYGFNNSDEPFALEKVIRPAVVVPESKRVDVLLKEFRSQRY
HMAIVVDEYGGVSGLVTIEDILEEIVGEIEDEFDHDSVEETEIRKVNNTVFMVKALTAIEDFNEEFGTDFSDEEFDTVGG
MVAHAFGHLPERNEQISIGGIEFKVISADTRRLIQLRVKFPDPEQAEIAEI

Specific function: Plays a role in the transport of magnesium and cobalt ions [H]

COG id: COG4535

COG function: function code P; Putative Mg2+ and Co2+ transporter CorC

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=213, Percent_Identity=33.8028169014084, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI94681046, Length=180, Percent_Identity=32.2222222222222, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI40068055, Length=184, Percent_Identity=28.2608695652174, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI40068053, Length=184, Percent_Identity=28.2608695652174, Blast_Score=69, Evalue=4e-12,
Organism=Escherichia coli, GI1786879, Length=286, Percent_Identity=60.1398601398601, Blast_Score=324, Evalue=4e-90,
Organism=Escherichia coli, GI145693175, Length=266, Percent_Identity=26.3157894736842, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788119, Length=243, Percent_Identity=31.6872427983539, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1790664, Length=261, Percent_Identity=24.1379310344828, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI87082033, Length=267, Percent_Identity=24.7191011235955, Blast_Score=90, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC [H]

EC number: NA

Molecular weight: Translated: 32987; Mature: 32855

Theoretical pI: Translated: 4.19; Mature: 4.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDDIPPSSNAQKKGWLERVSQLFQGEPQNRDDLVEVIHDAEQRDLITEDTREMIQGVLE
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHCCHHHHHHHHHHHHHH
VSDLRVRDIMIPRAQIVAIKIDSTVEELLATVIGSAHSRFPVVNDDKDHIEGILLAKDLI
HHCCHHHHEECCCEEEEEEEECHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
KYGFNNSDEPFALEKVIRPAVVVPESKRVDVLLKEFRSQRYHMAIVVDEYGGVSGLVTIE
HHCCCCCCCCHHHHHHHCCCEECCCCCHHHHHHHHHHCCCEEEEEEEECCCCCCCEEEHH
DILEEIVGEIEDEFDHDSVEETEIRKVNNTVFMVKALTAIEDFNEEFGTDFSDEEFDTVG
HHHHHHHHHHHHHCCCCCCCHHHHHHHCCCEEEHHHHHHHHHHHHHHCCCCCCCHHHHHH
GMVAHAFGHLPERNEQISIGGIEFKVISADTRRLIQLRVKFPDPEQAEIAEI
HHHHHHHCCCCCCCCEEEECCEEEEEECCCHHEEEEEEEECCCCCCCHHCCC
>Mature Secondary Structure 
SDDIPPSSNAQKKGWLERVSQLFQGEPQNRDDLVEVIHDAEQRDLITEDTREMIQGVLE
CCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHCCHHHHHHHHHHHHHH
VSDLRVRDIMIPRAQIVAIKIDSTVEELLATVIGSAHSRFPVVNDDKDHIEGILLAKDLI
HHCCHHHHEECCCEEEEEEEECHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
KYGFNNSDEPFALEKVIRPAVVVPESKRVDVLLKEFRSQRYHMAIVVDEYGGVSGLVTIE
HHCCCCCCCCHHHHHHHCCCEECCCCCHHHHHHHHHHCCCEEEEEEEECCCCCCCEEEHH
DILEEIVGEIEDEFDHDSVEETEIRKVNNTVFMVKALTAIEDFNEEFGTDFSDEEFDTVG
HHHHHHHHHHHHHCCCCCCCHHHHHHHCCCEEEHHHHHHHHHHHHHHCCCCCCCHHHHHH
GMVAHAFGHLPERNEQISIGGIEFKVISADTRRLIQLRVKFPDPEQAEIAEI
HHHHHHHCCCCCCCCEEEECCEEEEEECCCHHEEEEEEEECCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]