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The map label for this gene is glsA

Identifier: 119775620

GI number: 119775620

Start: 2990074

End: 2990988

Strand: Reverse

Name: glsA

Synonym: Sama_2487

Alternate gene names: 119775620

Gene position: 2990988-2990074 (Counterclockwise)

Preceding gene: 119775621

Following gene: 119775619

Centisome position: 69.46

GC content: 55.63

Gene sequence:

>915_bases
ATGCTTGAGCAGGCTCTGCTTGACGACCTGGTCGCCAAAGTTAGACCCTTGCTTGGGCAGGGCAAGGTGGCGGATTACAT
TCCGGCCCTTGCCCGGGTCTCCCCCTATAAGTTGGGCATTGCGGTAACCACCATTGATGGTACCACCCTGGGGGCGGGCG
ATTGGCAAGAAGCCTTTTCCATTCAAAGTATTTCCAAAGTATTCAGCCTTACCGGCGCAATGATGCTCTATGAAGAGCGT
GAGATTTGGTCGCGGGTAGGTAAAGAGCCGTCAGGTCACTCTTTTAACTCGCTGGTTCAGGTTGAACTTGAGCGGGGCAT
TCCACGTAATCCCTTTATCAACGCCGGCGCTCTGGTGATAGCCGATTTGTTGCAAAGCCGCTTGGGTGCGCCCAAACAGC
GGATGCTGGAAATAGTGCGTATGCTGAGCCAGAACCACAAAGTCTGTTATGACAAGGTGGTGGCCGACTCTGAATACCAG
CACAGCGCCCGTAATGCTGCCATCGCCTTTTTGATGAAGTCTTTCGGCAACTTCCATAACGATGTGGACAAGGTGCTCCG
AAGCTATTTCCATTACTGCTCACTCTCCATGAGCTGTGCCGATCTCTCCCGCGCCATGGTGTATCTGGCCAACCAGGGCG
TTAGCCTGGATGGCAATGAGGTGGTATCGCCCACCCAAACCCGGCGCCTGAATGCGCTGCTTGCCACATCAGGGCTCTAT
GATGGGGCAGGGGAGTTTGCCTACCGCGTGGGTATGCCGGGTAAAAGCGGTGTGGGTGGCGGAATTATTGCGGTGATCCC
CGGCGACATGTCGGTATGTGTGTGGTCGCCGGCCCTCGATGCCAGTGGTAACAGCTTGGCGGGTACCCGTCTGCTTGAGC
TGTTGGCACAGGAACTTGGCCGTTCAATCTTCTGA

Upstream 100 bases:

>100_bases
CACCGATGAAGACCGCGCCGCTGTGAAGGCATTCCTTGAAGGCCAGAAAGTGGCCAAAGTGGAAGTATCCGACCTGTACG
ATCTGTGGTGGGATTAATCC

Downstream 100 bases:

>100_bases
TCGTGCTGTCTTTTTAATTTGCTCTACCCCCGTGGCCTTTCTGATTTGAGGAAGGCCATTTCCTTATTTCGGCAACTTAT
CTGCCGCATTTTCAATCTTG

Product: glutaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MLEQALLDDLVAKVRPLLGQGKVADYIPALARVSPYKLGIAVTTIDGTTLGAGDWQEAFSIQSISKVFSLTGAMMLYEER
EIWSRVGKEPSGHSFNSLVQVELERGIPRNPFINAGALVIADLLQSRLGAPKQRMLEIVRMLSQNHKVCYDKVVADSEYQ
HSARNAAIAFLMKSFGNFHNDVDKVLRSYFHYCSLSMSCADLSRAMVYLANQGVSLDGNEVVSPTQTRRLNALLATSGLY
DGAGEFAYRVGMPGKSGVGGGIIAVIPGDMSVCVWSPALDASGNSLAGTRLLELLAQELGRSIF

Sequences:

>Translated_304_residues
MLEQALLDDLVAKVRPLLGQGKVADYIPALARVSPYKLGIAVTTIDGTTLGAGDWQEAFSIQSISKVFSLTGAMMLYEER
EIWSRVGKEPSGHSFNSLVQVELERGIPRNPFINAGALVIADLLQSRLGAPKQRMLEIVRMLSQNHKVCYDKVVADSEYQ
HSARNAAIAFLMKSFGNFHNDVDKVLRSYFHYCSLSMSCADLSRAMVYLANQGVSLDGNEVVSPTQTRRLNALLATSGLY
DGAGEFAYRVGMPGKSGVGGGIIAVIPGDMSVCVWSPALDASGNSLAGTRLLELLAQELGRSIF
>Mature_304_residues
MLEQALLDDLVAKVRPLLGQGKVADYIPALARVSPYKLGIAVTTIDGTTLGAGDWQEAFSIQSISKVFSLTGAMMLYEER
EIWSRVGKEPSGHSFNSLVQVELERGIPRNPFINAGALVIADLLQSRLGAPKQRMLEIVRMLSQNHKVCYDKVVADSEYQ
HSARNAAIAFLMKSFGNFHNDVDKVLRSYFHYCSLSMSCADLSRAMVYLANQGVSLDGNEVVSPTQTRRLNALLATSGLY
DGAGEFAYRVGMPGKSGVGGGIIAVIPGDMSVCVWSPALDASGNSLAGTRLLELLAQELGRSIF

Specific function: Unknown

COG id: COG2066

COG function: function code E; Glutaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutaminase family

Homologues:

Organism=Homo sapiens, GI156104878, Length=294, Percent_Identity=35.7142857142857, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI20336214, Length=294, Percent_Identity=33.6734693877551, Blast_Score=157, Evalue=1e-38,
Organism=Escherichia coli, GI1787804, Length=304, Percent_Identity=63.8157894736842, Blast_Score=414, Evalue=1e-117,
Organism=Escherichia coli, GI1786693, Length=305, Percent_Identity=36.0655737704918, Blast_Score=174, Evalue=7e-45,
Organism=Caenorhabditis elegans, GI17507019, Length=285, Percent_Identity=35.4385964912281, Blast_Score=172, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI17532727, Length=298, Percent_Identity=33.5570469798658, Blast_Score=170, Evalue=9e-43,
Organism=Caenorhabditis elegans, GI193204073, Length=291, Percent_Identity=34.020618556701, Blast_Score=160, Evalue=6e-40,
Organism=Caenorhabditis elegans, GI193204075, Length=293, Percent_Identity=33.7883959044369, Blast_Score=159, Evalue=2e-39,
Organism=Drosophila melanogaster, GI281363241, Length=285, Percent_Identity=36.140350877193, Blast_Score=173, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24653156, Length=285, Percent_Identity=36.140350877193, Blast_Score=173, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24653158, Length=285, Percent_Identity=36.140350877193, Blast_Score=172, Evalue=2e-43,
Organism=Drosophila melanogaster, GI281363239, Length=285, Percent_Identity=36.140350877193, Blast_Score=172, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24653162, Length=285, Percent_Identity=36.140350877193, Blast_Score=172, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24653164, Length=285, Percent_Identity=36.140350877193, Blast_Score=172, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24653166, Length=285, Percent_Identity=36.140350877193, Blast_Score=172, Evalue=2e-43,
Organism=Drosophila melanogaster, GI116008307, Length=285, Percent_Identity=36.140350877193, Blast_Score=172, Evalue=2e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLSA_SHEAM (A1S8I4)

Other databases:

- EMBL:   CP000507
- RefSeq:   YP_928360.1
- ProteinModelPortal:   A1S8I4
- SMR:   A1S8I4
- STRING:   A1S8I4
- GeneID:   4604735
- GenomeReviews:   CP000507_GR
- KEGG:   saz:Sama_2487
- NMPDR:   fig|326297.7.peg.2328
- eggNOG:   COG2066
- HOGENOM:   HBG512335
- OMA:   NALMLTC
- PhylomeDB:   A1S8I4
- ProtClustDB:   PRK00971
- HAMAP:   MF_00313
- InterPro:   IPR012338
- InterPro:   IPR015868
- Gene3D:   G3DSA:3.40.710.20
- PANTHER:   PTHR12544
- TIGRFAMs:   TIGR03814

Pfam domain/function: PF04960 Glutaminase; SSF56601 PBP_transp_fold

EC number: =3.5.1.2

Molecular weight: Translated: 32878; Mature: 32878

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEQALLDDLVAKVRPLLGQGKVADYIPALARVSPYKLGIAVTTIDGTTLGAGDWQEAFS
CCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCEEEEEEEEEECCCCCCCCCHHHHHH
IQSISKVFSLTGAMMLYEEREIWSRVGKEPSGHSFNSLVQVELERGIPRNPFINAGALVI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHEEEHHHCCCCCCCCCCCHHHHH
ADLLQSRLGAPKQRMLEIVRMLSQNHKVCYDKVVADSEYQHSARNAAIAFLMKSFGNFHN
HHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHH
DVDKVLRSYFHYCSLSMSCADLSRAMVYLANQGVSLDGNEVVSPTQTRRLNALLATSGLY
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
DGAGEFAYRVGMPGKSGVGGGIIAVIPGDMSVCVWSPALDASGNSLAGTRLLELLAQELG
CCCCCCEEEECCCCCCCCCCCEEEEECCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHC
RSIF
CCCC
>Mature Secondary Structure
MLEQALLDDLVAKVRPLLGQGKVADYIPALARVSPYKLGIAVTTIDGTTLGAGDWQEAFS
CCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCEEEEEEEEEECCCCCCCCCHHHHHH
IQSISKVFSLTGAMMLYEEREIWSRVGKEPSGHSFNSLVQVELERGIPRNPFINAGALVI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHEEEHHHCCCCCCCCCCCHHHHH
ADLLQSRLGAPKQRMLEIVRMLSQNHKVCYDKVVADSEYQHSARNAAIAFLMKSFGNFHN
HHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHH
DVDKVLRSYFHYCSLSMSCADLSRAMVYLANQGVSLDGNEVVSPTQTRRLNALLATSGLY
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
DGAGEFAYRVGMPGKSGVGGGIIAVIPGDMSVCVWSPALDASGNSLAGTRLLELLAQELG
CCCCCCEEEECCCCCCCCCCCEEEEECCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHC
RSIF
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA