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The map label for this gene is gpwA [H]

Identifier: 119775607

GI number: 119775607

Start: 2977327

End: 2977869

Strand: Reverse

Name: gpwA [H]

Synonym: Sama_2474

Alternate gene names: 119775607

Gene position: 2977869-2977327 (Counterclockwise)

Preceding gene: 119775608

Following gene: 119775602

Centisome position: 69.15

GC content: 52.12

Gene sequence:

>543_bases
ATGGCAGAAACTGTTGAGACTCAAAACGCCGCGGAGCACACTGCGGGCACGCAAGTCGCTTGTCCTGCGTATCTCAATCA
CGAGTTTCGTAAGCTGCACTCAAGTGAGTCGGTGAACCTTTGCGATATTGCCGCCGGCAAACCAGTGCTCTTTATCAATA
CCGCCAGCAACTGCGGCTTTACGCCACAGTTCAAGGCGCTTGAGCTGCTCAACAAGGAATATGGCCCCAAGGGACTGGTG
CTGGTGGGTTTTCCATCCGATGACTTCTTTCAGGAAGAAAACGATGAAAAGGATACCGCCAAGGTATGCTACCTCAACTA
TGGTGTGACCTTTACCATGCTGGCCACATCGGCGGTGCGTGGAGGTGATGCCAATCCTGTGTTTGAGTATTTGGGCGAAA
AAGCCGGTTCACCCAAGTGGAATTTCTACAAGTATCTGGTGTCTGCCGATGGCAAAGAAGTGACGGCTTTCAACTCCCGT
GTAAAGCCTGACAGCCTTGAGCTTAAAGCCGCTATCGAGGCTGCCTTGCCCAAAGCACTCTGA

Upstream 100 bases:

>100_bases
TATTTTCGGTCGGGAAGGTCATTGAAGAGATAGGTATTCAGGAGTCAGAATGCGTAGCTTATTGTTTTCATTACTGCTGG
TTTCAGGTGTTCATCCGGCA

Downstream 100 bases:

>100_bases
GTGTTTCAGGCAAGGGGAGACGAAATAAAAAACGCCGCATTCAGCGGCGTTTTTTATTTTGGCAACATCAGGCACCATAT
TGATTTTCAAAGTAACTTTC

Product: glutathione peroxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 180; Mature: 179

Protein sequence:

>180_residues
MAETVETQNAAEHTAGTQVACPAYLNHEFRKLHSSESVNLCDIAAGKPVLFINTASNCGFTPQFKALELLNKEYGPKGLV
LVGFPSDDFFQEENDEKDTAKVCYLNYGVTFTMLATSAVRGGDANPVFEYLGEKAGSPKWNFYKYLVSADGKEVTAFNSR
VKPDSLELKAAIEAALPKAL

Sequences:

>Translated_180_residues
MAETVETQNAAEHTAGTQVACPAYLNHEFRKLHSSESVNLCDIAAGKPVLFINTASNCGFTPQFKALELLNKEYGPKGLV
LVGFPSDDFFQEENDEKDTAKVCYLNYGVTFTMLATSAVRGGDANPVFEYLGEKAGSPKWNFYKYLVSADGKEVTAFNSR
VKPDSLELKAAIEAALPKAL
>Mature_179_residues
AETVETQNAAEHTAGTQVACPAYLNHEFRKLHSSESVNLCDIAAGKPVLFINTASNCGFTPQFKALELLNKEYGPKGLVL
VGFPSDDFFQEENDEKDTAKVCYLNYGVTFTMLATSAVRGGDANPVFEYLGEKAGSPKWNFYKYLVSADGKEVTAFNSRV
KPDSLELKAAIEAALPKAL

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI15618997, Length=138, Percent_Identity=38.4057971014493, Blast_Score=94, Evalue=4e-20,
Organism=Homo sapiens, GI192455698, Length=127, Percent_Identity=32.2834645669291, Blast_Score=74, Evalue=6e-14,
Organism=Homo sapiens, GI4557629, Length=149, Percent_Identity=30.2013422818792, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI1788003, Length=160, Percent_Identity=30, Blast_Score=81, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI193210707, Length=146, Percent_Identity=32.8767123287671, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319721, Length=145, Percent_Identity=46.2068965517241, Blast_Score=113, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6322228, Length=132, Percent_Identity=43.9393939393939, Blast_Score=109, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6322826, Length=137, Percent_Identity=41.6058394160584, Blast_Score=93, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24656772, Length=142, Percent_Identity=32.3943661971831, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24656777, Length=142, Percent_Identity=32.3943661971831, Blast_Score=67, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24656767, Length=142, Percent_Identity=32.3943661971831, Blast_Score=67, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: =1.11.1.9 [H]

Molecular weight: Translated: 19597; Mature: 19466

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS00460 GLUTATHIONE_PEROXID_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAETVETQNAAEHTAGTQVACPAYLNHEFRKLHSSESVNLCDIAAGKPVLFINTASNCGF
CCCCCCCCCCHHHCCCCCEECHHHHHHHHHHHHCCCCCCEEEECCCCCEEEEECCCCCCC
TPQFKALELLNKEYGPKGLVLVGFPSDDFFQEENDEKDTAKVCYLNYGVTFTMLATSAVR
CCCHHHHHHHHHCCCCCCEEEEECCCCHHHCCCCCCCCCEEEEEEECCCEEEEEHHHHHC
GGDANPVFEYLGEKAGSPKWNFYKYLVSADGKEVTAFNSRVKPDSLELKAAIEAALPKAL
CCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AETVETQNAAEHTAGTQVACPAYLNHEFRKLHSSESVNLCDIAAGKPVLFINTASNCGF
CCCCCCCCCHHHCCCCCEECHHHHHHHHHHHHCCCCCCEEEECCCCCEEEEECCCCCCC
TPQFKALELLNKEYGPKGLVLVGFPSDDFFQEENDEKDTAKVCYLNYGVTFTMLATSAVR
CCCHHHHHHHHHCCCCCCEEEEECCCCHHHCCCCCCCCCEEEEEEECCCEEEEEHHHHHC
GGDANPVFEYLGEKAGSPKWNFYKYLVSADGKEVTAFNSRVKPDSLELKAAIEAALPKAL
CCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA