Click here to switch to the map view.

The map label for this gene is yeiR [H]

Identifier: 119775580

GI number: 119775580

Start: 2943939

End: 2944979

Strand: Reverse

Name: yeiR [H]

Synonym: Sama_2446

Alternate gene names: 119775580

Gene position: 2944979-2943939 (Counterclockwise)

Preceding gene: 119775581

Following gene: 119775579

Centisome position: 68.39

GC content: 56.77

Gene sequence:

>1041_bases
ATGTTGCTTGGGAATATCCCCGTCAATGTCATCACAGGTTTTTTGGGCGCAGGTAAAACCAGTTTTATCAAAAAATTACT
GGCACAAAAGCCCGAAGGAGAAACCTGGGCCGTTCTGGTGAACGAATTTGGCGAAGTCGGCCTGGATGCCGCCTTGCTGG
GAAGCCGCGAGGGGCTGGCCATCCGTGAGGTGCCCGGGGGCTGTATTTGCTGCGCCGCCGGGGTGCCCACCAGGGTGGCC
GTCGCTCAGCTGCTGAGGCAAGCCAAACCCAGCCGTCTTTTGATTGAACCCACGGGACTTGGCCATCCTGCCAATATTCT
CAAAACCCTGATGGCTCCGGAGTATCAGGGGGTGTTATCCATCCAGCGCACCCTGTGTTTGGTGGACCCGCGAAATCTTG
ATGATGCGCGCTATACCCAAAACGACATCTTCAACCAGCAGCTGGCGGTGGCCGATCTGGTGCTGGCCTGCAAGGCCGAT
ATGCAGGCTCCGGACTTTCTCGCGACCCTTGGCTCCTATGTCACAGACATCAACCCCGGCGTCTCCGTGCAGCCCTTTTC
TGCTAAAACGCCTGTTTCCGATACCCTGCTCACGGCCATGATGCAAGTATCGATCAGGGCGCCGCAGCTGATGTCCGCAG
CTCTTCCCCGGGGCCTCTTTGCCAGCAAACCGTCAGGCACCATGGGCCTCTTTGATGAAGGCGATGGCGCACAGACTTTG
CAATTAAACTCACAAGGCTTTATCCGCAAACCCCATCAGGCCGAAGGTATTTTTGCCTGTGGCTGGTGTTTCAGTGCCCA
GTGGTGCTTTGACTTTGATGCCCTGATGGCCGTGGTCCAGGCCAATCCCAGTCTGAGACTCAAGGCGGTGATGATCACCC
CGGATGGCATTCTGGCCATTAACCGGCTGGAGACAGAATTGAATCTGGCGGAGCTGGATGATGCCATGGACTCCCGCATC
GAATTTATTGCCACAGAGCCCCTCGACTGGGATGCCATTGAAGAAGCGCTGCTGACAAGTGGCAGCCCAGTTGGCCAATA
G

Upstream 100 bases:

>100_bases
GGCCGGATTTTAGCGCGTTGCCGTTTACCGCTGTGTTTCCACCGCGAGCGGCTGCACACCGAAAAAGGCAAAGGGCCAGT
TGGGCCGAAGGAGTCTTGCC

Downstream 100 bases:

>100_bases
TTGGGGCGCAGAGTCAAACCCTGTATTCAACAGATCCTTAGCGTCCATCACGCGGTCTATACCCACGTTCTGACTGGGCA
CTGGTTCAGACGAGGCAGGC

Product: cobalamin synthesis protein/P47K family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MLLGNIPVNVITGFLGAGKTSFIKKLLAQKPEGETWAVLVNEFGEVGLDAALLGSREGLAIREVPGGCICCAAGVPTRVA
VAQLLRQAKPSRLLIEPTGLGHPANILKTLMAPEYQGVLSIQRTLCLVDPRNLDDARYTQNDIFNQQLAVADLVLACKAD
MQAPDFLATLGSYVTDINPGVSVQPFSAKTPVSDTLLTAMMQVSIRAPQLMSAALPRGLFASKPSGTMGLFDEGDGAQTL
QLNSQGFIRKPHQAEGIFACGWCFSAQWCFDFDALMAVVQANPSLRLKAVMITPDGILAINRLETELNLAELDDAMDSRI
EFIATEPLDWDAIEEALLTSGSPVGQ

Sequences:

>Translated_346_residues
MLLGNIPVNVITGFLGAGKTSFIKKLLAQKPEGETWAVLVNEFGEVGLDAALLGSREGLAIREVPGGCICCAAGVPTRVA
VAQLLRQAKPSRLLIEPTGLGHPANILKTLMAPEYQGVLSIQRTLCLVDPRNLDDARYTQNDIFNQQLAVADLVLACKAD
MQAPDFLATLGSYVTDINPGVSVQPFSAKTPVSDTLLTAMMQVSIRAPQLMSAALPRGLFASKPSGTMGLFDEGDGAQTL
QLNSQGFIRKPHQAEGIFACGWCFSAQWCFDFDALMAVVQANPSLRLKAVMITPDGILAINRLETELNLAELDDAMDSRI
EFIATEPLDWDAIEEALLTSGSPVGQ
>Mature_346_residues
MLLGNIPVNVITGFLGAGKTSFIKKLLAQKPEGETWAVLVNEFGEVGLDAALLGSREGLAIREVPGGCICCAAGVPTRVA
VAQLLRQAKPSRLLIEPTGLGHPANILKTLMAPEYQGVLSIQRTLCLVDPRNLDDARYTQNDIFNQQLAVADLVLACKAD
MQAPDFLATLGSYVTDINPGVSVQPFSAKTPVSDTLLTAMMQVSIRAPQLMSAALPRGLFASKPSGTMGLFDEGDGAQTL
QLNSQGFIRKPHQAEGIFACGWCFSAQWCFDFDALMAVVQANPSLRLKAVMITPDGILAINRLETELNLAELDDAMDSRI
EFIATEPLDWDAIEEALLTSGSPVGQ

Specific function: Unknown

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI126722884, Length=185, Percent_Identity=29.1891891891892, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI223941779, Length=185, Percent_Identity=29.1891891891892, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI33469141, Length=184, Percent_Identity=28.804347826087, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1788499, Length=332, Percent_Identity=40.9638554216867, Blast_Score=225, Evalue=3e-60,
Organism=Escherichia coli, GI87082430, Length=163, Percent_Identity=35.5828220858896, Blast_Score=79, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6324356, Length=254, Percent_Identity=25.5905511811024, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 37013; Mature: 37013

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLGNIPVNVITGFLGAGKTSFIKKLLAQKPEGETWAVLVNEFGEVGLDAALLGSREGLA
CCCCCCCHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEEEEHHHHHCCCCHHHHCCCCCEE
IREVPGGCICCAAGVPTRVAVAQLLRQAKPSRLLIEPTGLGHPANILKTLMAPEYQGVLS
EEECCCCEEEECCCCCHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHCCCHHHHHH
IQRTLCLVDPRNLDDARYTQNDIFNQQLAVADLVLACKADMQAPDFLATLGSYVTDINPG
HHHEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCC
VSVQPFSAKTPVSDTLLTAMMQVSIRAPQLMSAALPRGLFASKPSGTMGLFDEGDGAQTL
CEECCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCCEECCCCCEEE
QLNSQGFIRKPHQAEGIFACGWCFSAQWCFDFDALMAVVQANPSLRLKAVMITPDGILAI
EECCCCCEECCCCCCCEEEEEHHCCCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCEEEE
NRLETELNLAELDDAMDSRIEFIATEPLDWDAIEEALLTSGSPVGQ
EHHHHHCCHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLLGNIPVNVITGFLGAGKTSFIKKLLAQKPEGETWAVLVNEFGEVGLDAALLGSREGLA
CCCCCCCHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEEEEHHHHHCCCCHHHHCCCCCEE
IREVPGGCICCAAGVPTRVAVAQLLRQAKPSRLLIEPTGLGHPANILKTLMAPEYQGVLS
EEECCCCEEEECCCCCHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHCCCHHHHHH
IQRTLCLVDPRNLDDARYTQNDIFNQQLAVADLVLACKADMQAPDFLATLGSYVTDINPG
HHHEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCC
VSVQPFSAKTPVSDTLLTAMMQVSIRAPQLMSAALPRGLFASKPSGTMGLFDEGDGAQTL
CEECCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCCCCEECCCCCEEE
QLNSQGFIRKPHQAEGIFACGWCFSAQWCFDFDALMAVVQANPSLRLKAVMITPDGILAI
EECCCCCEECCCCCCCEEEEEHHCCCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCEEEE
NRLETELNLAELDDAMDSRIEFIATEPLDWDAIEEALLTSGSPVGQ
EHHHHHCCHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]