Click here to switch to the map view.

The map label for this gene is lutB [H]

Identifier: 119775576

GI number: 119775576

Start: 2939174

End: 2940574

Strand: Direct

Name: lutB [H]

Synonym: Sama_2442

Alternate gene names: 119775576

Gene position: 2939174-2940574 (Clockwise)

Preceding gene: 119775575

Following gene: 119775577

Centisome position: 68.26

GC content: 57.67

Gene sequence:

>1401_bases
ATGCAAAAAGTCATTCAGACCCATGCCAAAGCCGCCGACATTTTTTGCCGCGACGAAAGCCGCGTAGATTGGCACTCCAA
AGCCCTGTGGGTACTCAGGGAAAAACGCGACAGAGCCGCCTCCAGCCTGCCGGAATGGGAAACCTTGCGAGCACTGGGTT
CCCAGATAAAACTCCATACCTTAAACCAGTTGCCAGGCTACCTCGAAGCCTTTGAGGCCAAGTGCCTCTCCCAGGGTGTA
AAAGTGCACTGGGCCAAAGACGGCGCCGAGCACAATCGCATCGTGCACGATATTCTCTCCCGCCATGGGGTGAAAAAGCT
GGTGAAGTCCAAGTCCATGCTCACCGAAGAGTGCCATCTCAATCCGTTCCTCGAGGGAAAAGGCATTGAGGTGATAGATA
CGGATTTGGGTGAGCGTATTATTCAGCTCAATCATCAGCCGCCTTCCCACATAGTGGTGCCCGCCATTCACATGAAAAAA
GAAGAAGTGGGTGACCTCTTTCACGAAAAGCTCGGCACGCCAAAGGGTGAAAGCGACCCCACCCGACTGACCCGTGCTGC
CCGTGCGCACCTGCGTGAGCAGTTCCTCAGCGCCGATGCAGCCATGACAGGGGTCAACATGGCTGTCGCCAGTGAAGGGG
CGGTTATCGTGTGCACCAACGAAGGCAACGCCGACATGGGCGCCAACCTGCCCAAGCTGCAGCTGCACTCCATGGGCATA
GATAAAATCGTGCCGGATCTCGACAGTGCCGCCGTGCTTTTGCGAATGCTGGCCCGCAATGCCACCGGCCAGCCCATCAC
CACCTATTCCAGCCTGTACCGTACACCCAAGCCCGGTGGCGAGATGCACGTCATCATCGTGGATAATGGCCGCAGCGCCA
TGATGCGCGACAAACTGCTGGGTGAAGCCCTCAAGTGTATCCGCTGCGGTGGTTGCCTCAATACCTGCCCCGTGTACCGT
CGCAGTGGTGGCTACAGCTATGGCCATACCATCCCCGGCCCCATCGGCATTGCCGTGGGTGCCGATGAAGATGACACCCA
TTCCAGCCCCTGGGCCTGTACCCTGTGTGGCTCCTGCAGCTTTGTGTGCCCCACCAAGGTGCCGCTGGATAAAATCATCT
TCCACCGCCGCAGACTCTACGCCGAACGCAAGAGCCTGCCCTATGGCAAGTCAGGCTATATGCCATTGGTGGGCCGCTTT
ATGGCCAGTCCCTTGCTGCTGGATACCGGCATGGCCGCGGCACGTATTGCACTGAAAATTCTGCCACACAGCCTGCTCAA
ACCCATGAGCGGTGCCTGGGGTAAATACCGCGAACTGCCTGCTGCGCCCGGCTCCAGTTTCGAAGGCTGGGTGAAAAAGA
ACAGACCCGAGCTGTTGGTGAAGTCTAAGGGGGAGAAATAA

Upstream 100 bases:

>100_bases
CTGATGCACCTGGACGGTACCATTCGCCGCAGACAATTGCCCATCGAGACCCGCCATCTGGCGCAAATTCTCAACGACGC
TCTGTAACAGGGGAAACCGC

Downstream 100 bases:

>100_bases
GATGTCCAAACAAGCGATTCTCGAGGCCCTGAAATCCTCCGCCATGGAAAAAGTGGCCATGCCAACCATAGACATAGCGC
CGGTAACGACAGACCTTAAG

Product: iron-sulfur cluster-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 466; Mature: 466

Protein sequence:

>466_residues
MQKVIQTHAKAADIFCRDESRVDWHSKALWVLREKRDRAASSLPEWETLRALGSQIKLHTLNQLPGYLEAFEAKCLSQGV
KVHWAKDGAEHNRIVHDILSRHGVKKLVKSKSMLTEECHLNPFLEGKGIEVIDTDLGERIIQLNHQPPSHIVVPAIHMKK
EEVGDLFHEKLGTPKGESDPTRLTRAARAHLREQFLSADAAMTGVNMAVASEGAVIVCTNEGNADMGANLPKLQLHSMGI
DKIVPDLDSAAVLLRMLARNATGQPITTYSSLYRTPKPGGEMHVIIVDNGRSAMMRDKLLGEALKCIRCGGCLNTCPVYR
RSGGYSYGHTIPGPIGIAVGADEDDTHSSPWACTLCGSCSFVCPTKVPLDKIIFHRRRLYAERKSLPYGKSGYMPLVGRF
MASPLLLDTGMAAARIALKILPHSLLKPMSGAWGKYRELPAAPGSSFEGWVKKNRPELLVKSKGEK

Sequences:

>Translated_466_residues
MQKVIQTHAKAADIFCRDESRVDWHSKALWVLREKRDRAASSLPEWETLRALGSQIKLHTLNQLPGYLEAFEAKCLSQGV
KVHWAKDGAEHNRIVHDILSRHGVKKLVKSKSMLTEECHLNPFLEGKGIEVIDTDLGERIIQLNHQPPSHIVVPAIHMKK
EEVGDLFHEKLGTPKGESDPTRLTRAARAHLREQFLSADAAMTGVNMAVASEGAVIVCTNEGNADMGANLPKLQLHSMGI
DKIVPDLDSAAVLLRMLARNATGQPITTYSSLYRTPKPGGEMHVIIVDNGRSAMMRDKLLGEALKCIRCGGCLNTCPVYR
RSGGYSYGHTIPGPIGIAVGADEDDTHSSPWACTLCGSCSFVCPTKVPLDKIIFHRRRLYAERKSLPYGKSGYMPLVGRF
MASPLLLDTGMAAARIALKILPHSLLKPMSGAWGKYRELPAAPGSSFEGWVKKNRPELLVKSKGEK
>Mature_466_residues
MQKVIQTHAKAADIFCRDESRVDWHSKALWVLREKRDRAASSLPEWETLRALGSQIKLHTLNQLPGYLEAFEAKCLSQGV
KVHWAKDGAEHNRIVHDILSRHGVKKLVKSKSMLTEECHLNPFLEGKGIEVIDTDLGERIIQLNHQPPSHIVVPAIHMKK
EEVGDLFHEKLGTPKGESDPTRLTRAARAHLREQFLSADAAMTGVNMAVASEGAVIVCTNEGNADMGANLPKLQLHSMGI
DKIVPDLDSAAVLLRMLARNATGQPITTYSSLYRTPKPGGEMHVIIVDNGRSAMMRDKLLGEALKCIRCGGCLNTCPVYR
RSGGYSYGHTIPGPIGIAVGADEDDTHSSPWACTLCGSCSFVCPTKVPLDKIIFHRRRLYAERKSLPYGKSGYMPLVGRF
MASPLLLDTGMAAARIALKILPHSLLKPMSGAWGKYRELPAAPGSSFEGWVKKNRPELLVKSKGEK

Specific function: Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate [H]

COG id: COG1139

COG function: function code C; Uncharacterized conserved protein containing a ferredoxin-like domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Escherichia coli, GI1786498, Length=436, Percent_Identity=38.7614678899083, Blast_Score=316, Evalue=2e-87,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR003741
- InterPro:   IPR004452
- InterPro:   IPR002698
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR022825 [H]

Pfam domain/function: PF02589 DUF162 [H]

EC number: NA

Molecular weight: Translated: 51266; Mature: 51266

Theoretical pI: Translated: 9.35; Mature: 9.35

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKVIQTHAKAADIFCRDESRVDWHSKALWVLREKRDRAASSLPEWETLRALGSQIKLHT
CCHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHEEEEE
LNQLPGYLEAFEAKCLSQGVKVHWAKDGAEHNRIVHDILSRHGVKKLVKSKSMLTEECHL
HHHCCHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NPFLEGKGIEVIDTDLGERIIQLNHQPPSHIVVPAIHMKKEEVGDLFHEKLGTPKGESDP
CCCCCCCCCEEEECHHHHHHHCCCCCCCCCEEECHHHHHHHHHHHHHHHHHCCCCCCCCH
TRLTRAARAHLREQFLSADAAMTGVNMAVASEGAVIVCTNEGNADMGANLPKLQLHSMGI
HHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCEEEEEECCCCCCCCCCCCCHHHHHCCH
DKIVPDLDSAAVLLRMLARNATGQPITTYSSLYRTPKPGGEMHVIIVDNGRSAMMRDKLL
HHHCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHH
GEALKCIRCGGCLNTCPVYRRSGGYSYGHTIPGPIGIAVGADEDDTHSSPWACTLCGSCS
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCEEEECCCCC
FVCPTKVPLDKIIFHRRRLYAERKSLPYGKSGYMPLVGRFMASPLLLDTGMAAARIALKI
EECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCHHHHCCHHHHHHHHHH
LPHSLLKPMSGAWGKYRELPAAPGSSFEGWVKKNRPELLVKSKGEK
HHHHHHHHHCCCCHHHHCCCCCCCCCCCHHHHCCCCCEEECCCCCC
>Mature Secondary Structure
MQKVIQTHAKAADIFCRDESRVDWHSKALWVLREKRDRAASSLPEWETLRALGSQIKLHT
CCHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHEEEEE
LNQLPGYLEAFEAKCLSQGVKVHWAKDGAEHNRIVHDILSRHGVKKLVKSKSMLTEECHL
HHHCCHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NPFLEGKGIEVIDTDLGERIIQLNHQPPSHIVVPAIHMKKEEVGDLFHEKLGTPKGESDP
CCCCCCCCCEEEECHHHHHHHCCCCCCCCCEEECHHHHHHHHHHHHHHHHHCCCCCCCCH
TRLTRAARAHLREQFLSADAAMTGVNMAVASEGAVIVCTNEGNADMGANLPKLQLHSMGI
HHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCEEEEEECCCCCCCCCCCCCHHHHHCCH
DKIVPDLDSAAVLLRMLARNATGQPITTYSSLYRTPKPGGEMHVIIVDNGRSAMMRDKLL
HHHCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHH
GEALKCIRCGGCLNTCPVYRRSGGYSYGHTIPGPIGIAVGADEDDTHSSPWACTLCGSCS
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCEEEECCCCC
FVCPTKVPLDKIIFHRRRLYAERKSLPYGKSGYMPLVGRFMASPLLLDTGMAAARIALKI
EECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCHHHHCCHHHHHHHHHH
LPHSLLKPMSGAWGKYRELPAAPGSSFEGWVKKNRPELLVKSKGEK
HHHHHHHHHCCCCHHHHCCCCCCCCCCCHHHHCCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA