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The map label for this gene is ushA [C]

Identifier: 119775504

GI number: 119775504

Start: 2847440

End: 2849161

Strand: Direct

Name: ushA [C]

Synonym: Sama_2370

Alternate gene names: 119775504

Gene position: 2847440-2849161 (Clockwise)

Preceding gene: 119775503

Following gene: 119775507

Centisome position: 66.13

GC content: 54.99

Gene sequence:

>1722_bases
GTGCAGACTTCAGCTTATTACCTGCAACTGGCACACATCAACGATTGCCACAGTAATTTCGATCCCGTCGCCCTGAGCCT
GTCGGTTGACCATCACGGCTCACAGATTCGCGTAGCTTGCCACAGCGGCGGATATGGCCGCATCGCAACCATACTGGAGC
AAGCCCGCGATAAGGCCAAGCGCGATAACCAGGCCTTTTTATTTCTCCATGGTGGCGATACCTTTCAAGGGACCCTCTAT
TTCAACGAGTTTAAGGGCCGCGCCAACGCCAAACTACTGAACATGCTCAGGCCCGATGCCATGGTACTGGGCAACCATGA
AATCGACAGTGGCAATGCCCCGCTCCACCGCTTTGTCGAGGCCATTGATTTTCCTATGCTGGCCGGCAACATGGACTTGA
GCGGCGAAGATCCCACCAAAGCATTTCCGCTGGCCCGGTTGCCCAATCTCTATTACCTCGATCCAAGTACCGGCTGTGCC
AGAGTCATAAAACATCCCCTCGGTGACAGAGAGCTCGCCATTGTCGGCATCACGCTGGATCAGATGAGTGTGATTGCCAG
GCCCGACCCGGATACCCATTTCGCCAATACGCTGGAAACCTGTAAACGCACGGTGAAGGCCCTCAAGGCTGAAGGCATAG
ATCATATTCTGGTGCTCAGCCATCTTGGTCTCGATGGTGACCGCAAACTGGCCGCTTCCGTGGATGGCATAAGCCTTATC
GTTGGTGGCCACAGCCATACCCTGATGGGAGATTTTGCCGAGTTGGGATTACCGGCCGTCCCCTGGGGCGAATGCGTCAA
TGGCACTGCCATATTGCATGCGGGCAAGTATGCCGAAACACTCGGGCTTGCAGACATCGGCTTTAACGAAAAGGGACTAG
TCACCGCCCTTAATGGCGGCAATTATCTGATGCTGGATGAACATCTGGTTATCGATGGCGGCGATGAGATGACACGCAAT
GCCATCATCGCCAGGCTGAAGGCCCATCCAAATATTCTCTGGCCAGCGCAGCATCCCGACGTCCAGCAGGTGATAGATAC
TGAGTTCCGACCCGCTATCCGTGCCCTGGATCATCAGGTACTTGCCATGGTTCCCCGAGAACTGGTGCACACCCGTTTGC
CCAGTAAGGCCTTGCCCCATGGCAGCGAAGTCGCCCCCTGGGTTAGCCGTGCCATGTACGAAGAGTCCCGCATTCTGGAT
GGTGCAGTCCAATTTGCGCTGCATAACGCTGGCGGTGTCAGGCAGTCTCTCAGCCGTGGCCAAATTACCCTTGCCGATGT
GCTTGGCCGCTTGTTGCCATTTGAACTGCCGCTGGTGAAATATGCCATCGAAGGTCAGTATCTGTTTGAGGCGCTTGAAT
CTGCCATCAACAGTGCAACCAATAACAGTGTTGTTGGCACAGGTGCGGGGAGCTTTCCTTATACCTTTGGTCTTAAGTAT
CACTATGATGGCCGTCGCCCCATGGGGGAGAGGGTGCTGTCATTAACGGTCGCGCAAAATAACATTTGGGTACCAGTAAA
GCGCCAGCAGGTGTATGTGGGGGTTTCATCGGCGTACACCGCATCGGGTAAGGAAGGTTATGATGCCCTGGCTTGCTGCC
ATTGGCAGGAGTCTATCGATGGCCTAACACTGCCCGGCGCCTTTATCCGCTTTATCCAACGCCACGGCGAAATTGCCGAT
GAGTTGGCGCCGCAGTTATCCTACGTCAGTCATCTTGGCTGA

Upstream 100 bases:

>100_bases
CAAGGAGAAAGGCATTCGACTGTCAGATGACCAGGACGGAGACCTTCACTCATTCTGATTTCTGCCCGGCTCTTGCCGGG
CATTGTTAATAAGGCGTTTT

Downstream 100 bases:

>100_bases
CGGCAGGGCTCATCCGCCTTCCGGGCGGCTGAGCCACTTTTCCATACTGAAATTCACCAGGATTTGCCCGTGTCTTGGGT
GTTCATTCCGGCTAAGCTCA

Product: 5'-nucleotidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 573; Mature: 573

Protein sequence:

>573_residues
MQTSAYYLQLAHINDCHSNFDPVALSLSVDHHGSQIRVACHSGGYGRIATILEQARDKAKRDNQAFLFLHGGDTFQGTLY
FNEFKGRANAKLLNMLRPDAMVLGNHEIDSGNAPLHRFVEAIDFPMLAGNMDLSGEDPTKAFPLARLPNLYYLDPSTGCA
RVIKHPLGDRELAIVGITLDQMSVIARPDPDTHFANTLETCKRTVKALKAEGIDHILVLSHLGLDGDRKLAASVDGISLI
VGGHSHTLMGDFAELGLPAVPWGECVNGTAILHAGKYAETLGLADIGFNEKGLVTALNGGNYLMLDEHLVIDGGDEMTRN
AIIARLKAHPNILWPAQHPDVQQVIDTEFRPAIRALDHQVLAMVPRELVHTRLPSKALPHGSEVAPWVSRAMYEESRILD
GAVQFALHNAGGVRQSLSRGQITLADVLGRLLPFELPLVKYAIEGQYLFEALESAINSATNNSVVGTGAGSFPYTFGLKY
HYDGRRPMGERVLSLTVAQNNIWVPVKRQQVYVGVSSAYTASGKEGYDALACCHWQESIDGLTLPGAFIRFIQRHGEIAD
ELAPQLSYVSHLG

Sequences:

>Translated_573_residues
MQTSAYYLQLAHINDCHSNFDPVALSLSVDHHGSQIRVACHSGGYGRIATILEQARDKAKRDNQAFLFLHGGDTFQGTLY
FNEFKGRANAKLLNMLRPDAMVLGNHEIDSGNAPLHRFVEAIDFPMLAGNMDLSGEDPTKAFPLARLPNLYYLDPSTGCA
RVIKHPLGDRELAIVGITLDQMSVIARPDPDTHFANTLETCKRTVKALKAEGIDHILVLSHLGLDGDRKLAASVDGISLI
VGGHSHTLMGDFAELGLPAVPWGECVNGTAILHAGKYAETLGLADIGFNEKGLVTALNGGNYLMLDEHLVIDGGDEMTRN
AIIARLKAHPNILWPAQHPDVQQVIDTEFRPAIRALDHQVLAMVPRELVHTRLPSKALPHGSEVAPWVSRAMYEESRILD
GAVQFALHNAGGVRQSLSRGQITLADVLGRLLPFELPLVKYAIEGQYLFEALESAINSATNNSVVGTGAGSFPYTFGLKY
HYDGRRPMGERVLSLTVAQNNIWVPVKRQQVYVGVSSAYTASGKEGYDALACCHWQESIDGLTLPGAFIRFIQRHGEIAD
ELAPQLSYVSHLG
>Mature_573_residues
MQTSAYYLQLAHINDCHSNFDPVALSLSVDHHGSQIRVACHSGGYGRIATILEQARDKAKRDNQAFLFLHGGDTFQGTLY
FNEFKGRANAKLLNMLRPDAMVLGNHEIDSGNAPLHRFVEAIDFPMLAGNMDLSGEDPTKAFPLARLPNLYYLDPSTGCA
RVIKHPLGDRELAIVGITLDQMSVIARPDPDTHFANTLETCKRTVKALKAEGIDHILVLSHLGLDGDRKLAASVDGISLI
VGGHSHTLMGDFAELGLPAVPWGECVNGTAILHAGKYAETLGLADIGFNEKGLVTALNGGNYLMLDEHLVIDGGDEMTRN
AIIARLKAHPNILWPAQHPDVQQVIDTEFRPAIRALDHQVLAMVPRELVHTRLPSKALPHGSEVAPWVSRAMYEESRILD
GAVQFALHNAGGVRQSLSRGQITLADVLGRLLPFELPLVKYAIEGQYLFEALESAINSATNNSVVGTGAGSFPYTFGLKY
HYDGRRPMGERVLSLTVAQNNIWVPVKRQQVYVGVSSAYTASGKEGYDALACCHWQESIDGLTLPGAFIRFIQRHGEIAD
ELAPQLSYVSHLG

Specific function: Degradation Of External Udp-Glucose To Uridine Monophosphate And Glucose-1-Phosphate, Which Can Then Be Used By The Cell. [C]

COG id: COG0737

COG function: function code F; 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 5'-nucleotidase family [H]

Homologues:

Organism=Homo sapiens, GI4505467, Length=541, Percent_Identity=25.6931608133087, Blast_Score=127, Evalue=4e-29,
Organism=Escherichia coli, GI1786687, Length=282, Percent_Identity=24.468085106383, Blast_Score=68, Evalue=1e-12,
Organism=Drosophila melanogaster, GI28573524, Length=593, Percent_Identity=27.4873524451939, Blast_Score=162, Evalue=5e-40,
Organism=Drosophila melanogaster, GI24641187, Length=540, Percent_Identity=27.4074074074074, Blast_Score=151, Evalue=1e-36,
Organism=Drosophila melanogaster, GI19922446, Length=522, Percent_Identity=25.8620689655172, Blast_Score=132, Evalue=5e-31,
Organism=Drosophila melanogaster, GI24654424, Length=522, Percent_Identity=25.8620689655172, Blast_Score=132, Evalue=5e-31,
Organism=Drosophila melanogaster, GI19922444, Length=579, Percent_Identity=25.2158894645941, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI221329836, Length=539, Percent_Identity=24.6753246753247, Blast_Score=128, Evalue=1e-29,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008334
- InterPro:   IPR006146
- InterPro:   IPR006179
- InterPro:   IPR004843
- InterPro:   IPR006420 [H]

Pfam domain/function: PF02872 5_nucleotid_C; PF00149 Metallophos [H]

EC number: =3.1.3.5 [H]

Molecular weight: Translated: 62492; Mature: 62492

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTSAYYLQLAHINDCHSNFDPVALSLSVDHHGSQIRVACHSGGYGRIATILEQARDKAK
CCCCEEEEEEEEEHHCCCCCCCEEEEEEECCCCCEEEEEEECCCCHHHHHHHHHHHHHHC
RDNQAFLFLHGGDTFQGTLYFNEFKGRANAKLLNMLRPDAMVLGNHEIDSGNAPLHRFVE
CCCCEEEEEECCCCEEEEEEEEECCCCCCHHHHHHHCCCEEEECCCCCCCCCCHHHHHHH
AIDFPMLAGNMDLSGEDPTKAFPLARLPNLYYLDPSTGCARVIKHPLGDRELAIVGITLD
HHCCCEEECCCCCCCCCCCCCCCHHHCCCEEEECCCCHHHHHHHCCCCCCCEEEEEEEHH
QMSVIARPDPDTHFANTLETCKRTVKALKAEGIDHILVLSHLGLDGDRKLAASVDGISLI
HEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHCCCCCCCEEEEECCCEEEE
VGGHSHTLMGDFAELGLPAVPWGECVNGTAILHAGKYAETLGLADIGFNEKGLVTALNGG
ECCCCCCHHHHHHHCCCCCCCCHHHCCCEEEEECCCHHHHCCCEECCCCCCCCEEEECCC
NYLMLDEHLVIDGGDEMTRNAIIARLKAHPNILWPAQHPDVQQVIDTEFRPAIRALDHQV
CEEEEECEEEEECCCHHHHHHHHHHHHCCCCEECCCCCCCHHHHHCCHHHHHHHHHHHHH
LAMVPRELVHTRLPSKALPHGSEVAPWVSRAMYEESRILDGAVQFALHNAGGVRQSLSRG
HHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCC
QITLADVLGRLLPFELPLVKYAIEGQYLFEALESAINSATNNSVVGTGAGSFPYTFGLKY
CEEHHHHHHHHCCCCCCHHHEEECHHHHHHHHHHHHHCCCCCCEEECCCCCCCEEEEEEE
HYDGRRPMGERVLSLTVAQNNIWVPVKRQQVYVGVSSAYTASGKEGYDALACCHWQESID
EECCCCCCCHHEEEEEEECCCEEEEEECCEEEEEECCCEECCCCCCCCHHEEEEHHHCCC
GLTLPGAFIRFIQRHGEIADELAPQLSYVSHLG
CEECCHHHHHHHHHHCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQTSAYYLQLAHINDCHSNFDPVALSLSVDHHGSQIRVACHSGGYGRIATILEQARDKAK
CCCCEEEEEEEEEHHCCCCCCCEEEEEEECCCCCEEEEEEECCCCHHHHHHHHHHHHHHC
RDNQAFLFLHGGDTFQGTLYFNEFKGRANAKLLNMLRPDAMVLGNHEIDSGNAPLHRFVE
CCCCEEEEEECCCCEEEEEEEEECCCCCCHHHHHHHCCCEEEECCCCCCCCCCHHHHHHH
AIDFPMLAGNMDLSGEDPTKAFPLARLPNLYYLDPSTGCARVIKHPLGDRELAIVGITLD
HHCCCEEECCCCCCCCCCCCCCCHHHCCCEEEECCCCHHHHHHHCCCCCCCEEEEEEEHH
QMSVIARPDPDTHFANTLETCKRTVKALKAEGIDHILVLSHLGLDGDRKLAASVDGISLI
HEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHCCCCCCCEEEEECCCEEEE
VGGHSHTLMGDFAELGLPAVPWGECVNGTAILHAGKYAETLGLADIGFNEKGLVTALNGG
ECCCCCCHHHHHHHCCCCCCCCHHHCCCEEEEECCCHHHHCCCEECCCCCCCCEEEECCC
NYLMLDEHLVIDGGDEMTRNAIIARLKAHPNILWPAQHPDVQQVIDTEFRPAIRALDHQV
CEEEEECEEEEECCCHHHHHHHHHHHHCCCCEECCCCCCCHHHHHCCHHHHHHHHHHHHH
LAMVPRELVHTRLPSKALPHGSEVAPWVSRAMYEESRILDGAVQFALHNAGGVRQSLSRG
HHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCC
QITLADVLGRLLPFELPLVKYAIEGQYLFEALESAINSATNNSVVGTGAGSFPYTFGLKY
CEEHHHHHHHHCCCCCCHHHEEECHHHHHHHHHHHHHCCCCCCEEECCCCCCCEEEEEEE
HYDGRRPMGERVLSLTVAQNNIWVPVKRQQVYVGVSSAYTASGKEGYDALACCHWQESID
EECCCCCCCHHEEEEEEECCCEEEEEECCEEEEEECCCEECCCCCCCCHHEEEEHHHCCC
GLTLPGAFIRFIQRHGEIADELAPQLSYVSHLG
CEECCHHHHHHHHHHCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9665876 [H]