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The map label for this gene is tadA [H]

Identifier: 119775487

GI number: 119775487

Start: 2825833

End: 2826405

Strand: Reverse

Name: tadA [H]

Synonym: Sama_2352

Alternate gene names: 119775487

Gene position: 2826405-2825833 (Counterclockwise)

Preceding gene: 119775489

Following gene: 119775485

Centisome position: 65.64

GC content: 54.97

Gene sequence:

>573_bases
TTGCCAGGTAAGGGAGGCGGCAGTTATACTGTGCCCATTAAAATTGGGGTGGAAATGACATTGCAACAAACAGAGCTGGA
CAAGCATTTTATGTCGCTTGCACTTGAGGCTGCCAAAGAGGCCGAGGCAAGGGGGGAAGTCCCCGTTGGGGCCGTCCTGG
TAAGAGAAGGGCTGGTCATTGCGACCGGCTATAACCACAATATTGGTCTTAACGATCCCAGCGCCCATGCAGAGATGCAG
TGCCTGCGGGAAGCCGGGCGTATGCTGGGCAATTATCGTCTGCTGGATACCACTCTTTATGTCACCCTTGAGCCCTGCGC
CATGTGTGCCGGTGTGATGGTGCACAGTCGTATTGAACGCCTGGTGTTTGGCGCAAAAGACGAGAAAACCGGCGCCGCCG
GCAGTGTGGTGGATTTGGTCAGGCACCCAGCCTTTAACCATCAAATACAGGTGGAGGAAGGTGTGTTGGCCGAGGAATGC
TCTGGCATGCTCAGCGATTTCTTCCGTCGTCGCCGTAAAGAGCAAAAAGCCCTTAAGCAGGCTGCCCGTGACACGCAGTC
TGCTTCGGAATAA

Upstream 100 bases:

>100_bases
GAGTAAGATATTGAATGTATAAGTGTCCGGATTGCTTATGAAAATGCATTAGCAGCGGCCTTTGAAATGTCTGACTAAAG
TCTAGCCACAGCCGCAGATT

Downstream 100 bases:

>100_bases
AAATAGGGTGGAAAGTGGGCGCAGGCCCTGTGCGATTAGTCTTCGGTTTGAATAAGACTGAAGAAGAGTTTTTGTCTGCG
CAGTAAACGACTGTGGCGGA

Product: cytidine/deoxycytidylate deaminase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 190; Mature: 189

Protein sequence:

>190_residues
MPGKGGGSYTVPIKIGVEMTLQQTELDKHFMSLALEAAKEAEARGEVPVGAVLVREGLVIATGYNHNIGLNDPSAHAEMQ
CLREAGRMLGNYRLLDTTLYVTLEPCAMCAGVMVHSRIERLVFGAKDEKTGAAGSVVDLVRHPAFNHQIQVEEGVLAEEC
SGMLSDFFRRRRKEQKALKQAARDTQSASE

Sequences:

>Translated_190_residues
MPGKGGGSYTVPIKIGVEMTLQQTELDKHFMSLALEAAKEAEARGEVPVGAVLVREGLVIATGYNHNIGLNDPSAHAEMQ
CLREAGRMLGNYRLLDTTLYVTLEPCAMCAGVMVHSRIERLVFGAKDEKTGAAGSVVDLVRHPAFNHQIQVEEGVLAEEC
SGMLSDFFRRRRKEQKALKQAARDTQSASE
>Mature_189_residues
PGKGGGSYTVPIKIGVEMTLQQTELDKHFMSLALEAAKEAEARGEVPVGAVLVREGLVIATGYNHNIGLNDPSAHAEMQC
LREAGRMLGNYRLLDTTLYVTLEPCAMCAGVMVHSRIERLVFGAKDEKTGAAGSVVDLVRHPAFNHQIQVEEGVLAEECS
GMLSDFFRRRRKEQKALKQAARDTQSASE

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=173, Percent_Identity=30.0578034682081, Blast_Score=77, Evalue=1e-14,
Organism=Escherichia coli, GI145693172, Length=158, Percent_Identity=57.5949367088608, Blast_Score=196, Evalue=6e-52,
Organism=Caenorhabditis elegans, GI17541138, Length=147, Percent_Identity=34.6938775510204, Blast_Score=84, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17554608, Length=106, Percent_Identity=36.7924528301887, Blast_Score=82, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17555996, Length=121, Percent_Identity=30.5785123966942, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6325319, Length=104, Percent_Identity=35.5769230769231, Blast_Score=66, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6322425, Length=160, Percent_Identity=33.125, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21355527, Length=147, Percent_Identity=31.9727891156463, Blast_Score=71, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 20699; Mature: 20568

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGKGGGSYTVPIKIGVEMTLQQTELDKHFMSLALEAAKEAEARGEVPVGAVLVREGLVI
CCCCCCCCEEEEEEECCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCEEE
ATGYNHNIGLNDPSAHAEMQCLREAGRMLGNYRLLDTTLYVTLEPCAMCAGVMVHSRIER
EECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEEEEECHHHHHHHHHHHHHHHH
LVFGAKDEKTGAAGSVVDLVRHPAFNHQIQVEEGVLAEECSGMLSDFFRRRRKEQKALKQ
HHHCCCCCCCCCCHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AARDTQSASE
HHHHHCCCCC
>Mature Secondary Structure 
PGKGGGSYTVPIKIGVEMTLQQTELDKHFMSLALEAAKEAEARGEVPVGAVLVREGLVI
CCCCCCCEEEEEEECCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCEEE
ATGYNHNIGLNDPSAHAEMQCLREAGRMLGNYRLLDTTLYVTLEPCAMCAGVMVHSRIER
EECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEEEEECHHHHHHHHHHHHHHHH
LVFGAKDEKTGAAGSVVDLVRHPAFNHQIQVEEGVLAEECSGMLSDFFRRRRKEQKALKQ
HHHCCCCCCCCCCHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AARDTQSASE
HHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]