Click here to switch to the map view.

The map label for this gene is neuA [H]

Identifier: 119775471

GI number: 119775471

Start: 2801716

End: 2802414

Strand: Direct

Name: neuA [H]

Synonym: Sama_2336

Alternate gene names: 119775471

Gene position: 2801716-2802414 (Clockwise)

Preceding gene: 119775470

Following gene: 119775472

Centisome position: 65.06

GC content: 43.78

Gene sequence:

>699_bases
ATGCTTAACGATAAACGTGTGCTGGCTCTCATACCTGCTCGAGGCGGCAGCAAACGCCTTCCGCGTAAAAATATTCGTCT
ACTTAAGGGTATTCCCCTTATTGGCTGGACCATTACAGCGGCTAAACAGAGTCAATACATTGATGAAATATTCATCAGTA
CTGATGACCAAGAAATACTCAGTTACGCCCAAACATTAGCTGTTTGGGCCCCAGAATTACGCCCCGCTGAACTGGCAACT
GACTCAGCCACAAGCTCTGATGTGCTTGTATATACATTAAACAAGTATGCTCATAATTATGACTTGGTAGTTTTGTTGCA
GCCAACCTCTCCATTCAGGAATGCTCAGCACATAGATGAAGCGTTGGAGCTGTTTATTGCAAATCAGGCGGAGGAGCTTG
CATCTGTAACCCCGTGTGAACATTCTCCCCTGTGGACCAATACCTTACCCGCAAACCATTCGCTCAATGGGTTCATCAAA
ACAGAAAACTTGAAAAGATCCCAGGAATTACCAGACTTTTACCGCTTCAACGGTGCCATTTATATATTTGATATTAAGTG
TTTTTTAATCAAAAAAAGCATTAGTTACGGTGAAAATAGCTTCGCTTATGTCATGGATAATGAACACTCGCTCGACATCG
ACACTGAGTATGATTTCAAGCTAGCCGAGGCCATCAGTAGCCTACAGACCCAGGCCTGA

Upstream 100 bases:

>100_bases
GAGTCTACACATTCCCTATCCATGAATATTGGCTGGATATTGGTCGAATGGATGAGTTCAACAAAGCACAATCTGACATA
GAAGTGTTAGGGATTAATTA

Downstream 100 bases:

>100_bases
TGGCTATTACCAACATAATTTTTATTAAATCAGATAATTATTGGTTAACGTGCGGATAGATATCGACATTCACCTTACAT
CAAACCCACCTGAGAATACG

Product: N-acylneuraminate cytidylyltransferase

Products: NA

Alternate protein names: CMP-N-acetylneuraminic acid synthase; CMP-NeuNAc synthase; CMP-sialic acid synthase [H]

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MLNDKRVLALIPARGGSKRLPRKNIRLLKGIPLIGWTITAAKQSQYIDEIFISTDDQEILSYAQTLAVWAPELRPAELAT
DSATSSDVLVYTLNKYAHNYDLVVLLQPTSPFRNAQHIDEALELFIANQAEELASVTPCEHSPLWTNTLPANHSLNGFIK
TENLKRSQELPDFYRFNGAIYIFDIKCFLIKKSISYGENSFAYVMDNEHSLDIDTEYDFKLAEAISSLQTQA

Sequences:

>Translated_232_residues
MLNDKRVLALIPARGGSKRLPRKNIRLLKGIPLIGWTITAAKQSQYIDEIFISTDDQEILSYAQTLAVWAPELRPAELAT
DSATSSDVLVYTLNKYAHNYDLVVLLQPTSPFRNAQHIDEALELFIANQAEELASVTPCEHSPLWTNTLPANHSLNGFIK
TENLKRSQELPDFYRFNGAIYIFDIKCFLIKKSISYGENSFAYVMDNEHSLDIDTEYDFKLAEAISSLQTQA
>Mature_232_residues
MLNDKRVLALIPARGGSKRLPRKNIRLLKGIPLIGWTITAAKQSQYIDEIFISTDDQEILSYAQTLAVWAPELRPAELAT
DSATSSDVLVYTLNKYAHNYDLVVLLQPTSPFRNAQHIDEALELFIANQAEELASVTPCEHSPLWTNTLPANHSLNGFIK
TENLKRSQELPDFYRFNGAIYIFDIKCFLIKKSISYGENSFAYVMDNEHSLDIDTEYDFKLAEAISSLQTQA

Specific function: Unknown

COG id: COG1083

COG function: function code M; CMP-N-acetylneuraminic acid synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CMP-NeuNAc synthase family [H]

Homologues:

Organism=Homo sapiens, GI8923900, Length=219, Percent_Identity=31.9634703196347, Blast_Score=96, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003329 [H]

Pfam domain/function: PF02348 CTP_transf_3 [H]

EC number: =2.7.7.43 [H]

Molecular weight: Translated: 26217; Mature: 26217

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNDKRVLALIPARGGSKRLPRKNIRLLKGIPLIGWTITAAKQSQYIDEIFISTDDQEIL
CCCCCEEEEEEECCCCCCCCCHHHHHHHCCCCEEEEEEEEHHHHHHHHHHEECCCHHHHH
SYAQTLAVWAPELRPAELATDSATSSDVLVYTLNKYAHNYDLVVLLQPTSPFRNAQHIDE
HHHHHHHHHCCCCCCHHHCCCCCCCCCEEEEEECHHCCCCEEEEEECCCCCCCCHHHHHH
ALELFIANQAEELASVTPCEHSPLWTNTLPANHSLNGFIKTENLKRSQELPDFYRFNGAI
HHHHHHCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEECCCCCHHHCCCHHHHHCCEE
YIFDIKCFLIKKSISYGENSFAYVMDNEHSLDIDTEYDFKLAEAISSLQTQA
EEEEEEEEEEEECCCCCCCCEEEEECCCCCEECCCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MLNDKRVLALIPARGGSKRLPRKNIRLLKGIPLIGWTITAAKQSQYIDEIFISTDDQEIL
CCCCCEEEEEEECCCCCCCCCHHHHHHHCCCCEEEEEEEEHHHHHHHHHHEECCCHHHHH
SYAQTLAVWAPELRPAELATDSATSSDVLVYTLNKYAHNYDLVVLLQPTSPFRNAQHIDE
HHHHHHHHHCCCCCCHHHCCCCCCCCCEEEEEECHHCCCCEEEEEECCCCCCCCHHHHHH
ALELFIANQAEELASVTPCEHSPLWTNTLPANHSLNGFIKTENLKRSQELPDFYRFNGAI
HHHHHHCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEECCCCCHHHCCCHHHHHCCEE
YIFDIKCFLIKKSISYGENSFAYVMDNEHSLDIDTEYDFKLAEAISSLQTQA
EEEEEEEEEEEECCCCCCCCEEEEECCCCCEECCCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1398032; 7830552; 8113198; 8045888; 10710307 [H]