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The map label for this gene is 119775466

Identifier: 119775466

GI number: 119775466

Start: 2797037

End: 2798035

Strand: Direct

Name: 119775466

Synonym: Sama_2331

Alternate gene names: NA

Gene position: 2797037-2798035 (Clockwise)

Preceding gene: 119775465

Following gene: 119775467

Centisome position: 64.95

GC content: 45.85

Gene sequence:

>999_bases
ATGGTTAAGACTTTTATCATCGCCGAAGCGGGCGTAAATCATAATGGCAATATTGCTCTGGCAAAGCAGCTAATTGACTC
TGCAGTGGAAGCCGGCGTTGATGCAGTAAAGTTCCAGACTTGGAAAACCGAATTGCTTGTCAGCAAAGATGCTGAAATGG
CTGCATATCAGATTGAAAACACACACAAAAAAGAGTCTCAATTTGAAATGCTCAAGAGACTTGAGCTGAGTTATCCCGAC
TTTATCGAGTTAAAGGCGTACTGTGATACTAAAAATATCTTGTTCCTTTCAACCCCAGACGAGCATGAAAGCGCTCGTTT
TTTAAACGGATTACAGAGTGTCTTTAAAATTGGATCCGGTGAACTGACCAACGTTCCATTCCTCAGGTTAATTGCAGGTT
TTGGTAAACCTGTGATCCTATCGACTGGCATGGGATACCTTTCAGAAGTGGAACAAGCACTGTTTGTGCTAACAGAAGCA
GGACTGGCACTAACGGATATAACGGTTTTACATGCAACCACCGACTACCCCACGGCGCCACAGGACGTAAACTTACGTGC
CATGCTGACTATTCAAAATGCGTTTCCCGGAGTTAAGGTCGGTTATTCCGACCATACTTTGGGGATTGAAGTATCTGTCG
CGGCAGTCGCCTTGGGTGCAAGTATCATTGAAAAACATTTTACGCTGGATAAAGCAATGCCGGGCCCCGATCACAAAGCG
AGCCTTGAACCTGCTGAACTGAAAGCGTTGGTGCAAGCCATTCGAAATGTCGAAGCATCCCTTGGGGATGGCCGAAAGCT
CCCCACGTCAACTGAAATGGTTAATCGAAAGCTCGTCAGAAAAAGTATCATCGCAAATACTTATATCAGCGCGGGCACAG
AGATAACCGCCGATATGTTGGATGTCAGACGTCCGGGAGATGGAATTTCCCCTTCTCGCTGGGATGAGGTAATCGGCAGT
ATCGCCAAAAAGGACTATCAATCAGGAGACCTCATTTAA

Upstream 100 bases:

>100_bases
CCCGAAAAGCGTATAGAACTGAACAAACTTTGGTGCGAATTGAGTACCACAGCAGAGATACCGGCAAGATTTCAGCTTTA
TAGAGCTTTGGAGCCCAATC

Downstream 100 bases:

>100_bases
TGCGGAAGATTTCCGTTGTGACAGCAACCCGAGCAGAATATGGATTGTTGAGAGGATTACTCGAGGACATCAATGCAGCA
TCGGAGCTGGAATTACAGCT

Product: N-acylneuraminate-9-phosphate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MVKTFIIAEAGVNHNGNIALAKQLIDSAVEAGVDAVKFQTWKTELLVSKDAEMAAYQIENTHKKESQFEMLKRLELSYPD
FIELKAYCDTKNILFLSTPDEHESARFLNGLQSVFKIGSGELTNVPFLRLIAGFGKPVILSTGMGYLSEVEQALFVLTEA
GLALTDITVLHATTDYPTAPQDVNLRAMLTIQNAFPGVKVGYSDHTLGIEVSVAAVALGASIIEKHFTLDKAMPGPDHKA
SLEPAELKALVQAIRNVEASLGDGRKLPTSTEMVNRKLVRKSIIANTYISAGTEITADMLDVRRPGDGISPSRWDEVIGS
IAKKDYQSGDLI

Sequences:

>Translated_332_residues
MVKTFIIAEAGVNHNGNIALAKQLIDSAVEAGVDAVKFQTWKTELLVSKDAEMAAYQIENTHKKESQFEMLKRLELSYPD
FIELKAYCDTKNILFLSTPDEHESARFLNGLQSVFKIGSGELTNVPFLRLIAGFGKPVILSTGMGYLSEVEQALFVLTEA
GLALTDITVLHATTDYPTAPQDVNLRAMLTIQNAFPGVKVGYSDHTLGIEVSVAAVALGASIIEKHFTLDKAMPGPDHKA
SLEPAELKALVQAIRNVEASLGDGRKLPTSTEMVNRKLVRKSIIANTYISAGTEITADMLDVRRPGDGISPSRWDEVIGS
IAKKDYQSGDLI
>Mature_332_residues
MVKTFIIAEAGVNHNGNIALAKQLIDSAVEAGVDAVKFQTWKTELLVSKDAEMAAYQIENTHKKESQFEMLKRLELSYPD
FIELKAYCDTKNILFLSTPDEHESARFLNGLQSVFKIGSGELTNVPFLRLIAGFGKPVILSTGMGYLSEVEQALFVLTEA
GLALTDITVLHATTDYPTAPQDVNLRAMLTIQNAFPGVKVGYSDHTLGIEVSVAAVALGASIIEKHFTLDKAMPGPDHKA
SLEPAELKALVQAIRNVEASLGDGRKLPTSTEMVNRKLVRKSIIANTYISAGTEITADMLDVRRPGDGISPSRWDEVIGS
IAKKDYQSGDLI

Specific function: Unknown

COG id: COG2089

COG function: function code M; Sialic acid synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis spsE [H]

Homologues:

Organism=Homo sapiens, GI12056473, Length=301, Percent_Identity=38.2059800664452, Blast_Score=206, Evalue=2e-53,
Organism=Drosophila melanogaster, GI21357081, Length=257, Percent_Identity=39.2996108949416, Blast_Score=182, Evalue=3e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006190
- InterPro:   IPR013785
- InterPro:   IPR013132
- InterPro:   IPR013974 [H]

Pfam domain/function: PF03102 NeuB; PF08666 SAF [H]

EC number: NA

Molecular weight: Translated: 36107; Mature: 36107

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS50844 AFP_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKTFIIAEAGVNHNGNIALAKQLIDSAVEAGVDAVKFQTWKTELLVSKDAEMAAYQIEN
CCEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCHHEEEEHHHHEEEEECCCHHHHHHHHC
THKKESQFEMLKRLELSYPDFIELKAYCDTKNILFLSTPDEHESARFLNGLQSVFKIGSG
CCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHCCCC
ELTNVPFLRLIAGFGKPVILSTGMGYLSEVEQALFVLTEAGLALTDITVLHATTDYPTAP
CCCCCHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCCCC
QDVNLRAMLTIQNAFPGVKVGYSDHTLGIEVSVAAVALGASIIEKHFTLDKAMPGPDHKA
CCCCEEEEEEEECCCCCCEECCCCCEEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
SLEPAELKALVQAIRNVEASLGDGRKLPTSTEMVNRKLVRKSIIANTYISAGTEITADML
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
DVRRPGDGISPSRWDEVIGSIAKKDYQSGDLI
HHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MVKTFIIAEAGVNHNGNIALAKQLIDSAVEAGVDAVKFQTWKTELLVSKDAEMAAYQIEN
CCEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCHHEEEEHHHHEEEEECCCHHHHHHHHC
THKKESQFEMLKRLELSYPDFIELKAYCDTKNILFLSTPDEHESARFLNGLQSVFKIGSG
CCCHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHCCCC
ELTNVPFLRLIAGFGKPVILSTGMGYLSEVEQALFVLTEAGLALTDITVLHATTDYPTAP
CCCCCHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCCCC
QDVNLRAMLTIQNAFPGVKVGYSDHTLGIEVSVAAVALGASIIEKHFTLDKAMPGPDHKA
CCCCEEEEEEEECCCCCCEECCCCCEEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
SLEPAELKALVQAIRNVEASLGDGRKLPTSTEMVNRKLVRKSIIANTYISAGTEITADML
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
DVRRPGDGISPSRWDEVIGSIAKKDYQSGDLI
HHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]