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The map label for this gene is yclF [H]

Identifier: 119775401

GI number: 119775401

Start: 2731622

End: 2733094

Strand: Direct

Name: yclF [H]

Synonym: Sama_2266

Alternate gene names: 119775401

Gene position: 2731622-2733094 (Clockwise)

Preceding gene: 119775369

Following gene: 119775404

Centisome position: 63.44

GC content: 52.95

Gene sequence:

>1473_bases
ATGAGCGAAAATTCCCAGGGTACGATGCTCGGGCATCCAAAGGGGCTGTTTCTGCTGTTCACAACGGAACTGTGGGAACG
ATTCAGTTATTACGCCATGCGTGCCATTTTGGTGCTGTATCTGGTTGACCGCGTACAAAGTGAGGGCGGTCATGGCTTAG
GTTGGAGCCAAGCCGATGCAATTTCTCTGTACGGTACTTTTACCGGCTTGGTGTACCTCACCCCGCTGCTGGGTGGCTGG
TTAGCCGATAATTTCCTTGGTCAACGTAAAGCCATCATGATTGGCGGCACCCTGATGGCTGCCGGCCAATTTATTCTGGG
TACTCCACACGCCTGGGTTCAAGGCATGGAGACCGAAGTATTCTACCTGGGTCTGGGTGTCCTTATCCTCGGTAACGGTC
TGTTCAAGCCCAACATTTCTACCATGGTGGGTGATCTGTATGCCGAAGGCGACCATCGCCGTGACGGCGCCTTTACCATC
TTCTACATGGGTATCAACGTAGGCGCCTTCCTGTCAGGTATCATCGTTGGCTCTGTAGTGAGCGCTTATGATGGTAACTT
CCAGGCTGGCTTTATCTGTGCCGGTATCGGAATGGTGCTTTCACTCATTATCCAATTCCTGTTTGCCCAAAAGTTGCTGG
GCAATATCGGTACTGTGCCTGCTGCCAAACTTGAGAAGCAAAAAGACGAGGCCCGCGGTCAGGTGCGTAAAGAGCCGCTG
ACTAAAGTTGAGCGCGACCGTATCAAAGTGATCATGGTGATGGGTCTGTTCACCATCGTATTCTGGGCAGGTTTTGAACA
GGCCGGCGGCCTGATGAACCTGTTTACCAACGATTTTACCGACCGCATGATTGGCAGCTGGGAAGTACCCACTACCTGGT
TCCAATCTCTGAACGCCATGTTCATCGTGATTTTTGCCCCTGTGGTTGCTTCTATTTGGGTACGCCTGGGCGACCGTGAG
CCAAACTCACCGGTTAAATTTGCGCTTGGCTTGGTTCTGCTGGCCATTGGCTTCCTGTTTATGATTGGTGCCGTGGTTGA
GATGGGTGGTGACCCAACTGCCAAGTCCAGCATGTGGTGGCTGGTTGGTGCCTACTTCTTCCACACCATGGGTGAACTGT
GCTTGTCTCCAATCGGTCTGTCTATGGTGACCAAGCTCGCTCCCCTGCGCATTGTATCGCTGATGATGGGGGCATGGTTC
CTGTTCATCGCCGCGGCCAACAAGATTGGTGGTGTCGTTGGCTCCTTTATCGGTCATGGTGGTGAGAAAGAAGAGCAGCT
GGCAAATGCCATGTCTATCTTCGCCGGTATCGCCATCACCGCCGCTATTTCAGGTGTGATCCTGTACTTCATGGCTGACA
AACTGGTTGATTGGATGCACGGCGCCGAAAGCAAAGTGCACCACACCGAAGAAGAAGCCCTTGAAGAGGAAATCGCCGTT
ACCGGCGAGCATGAAGCGATGAAGCGCAGCTGA

Upstream 100 bases:

>100_bases
ACAGATGCTTAATGTTAATTGTGTTGTCCGGAATGTCACATTTTATGTTTCGTAGAGCCACTGCTTTACGTGCAATCACA
AGCTTAAGGTGGAAGACTTA

Downstream 100 bases:

>100_bases
TAACAGCAGCGTCGCTACGCGACTTCTAGAAAAAGCAGAGCGCTTCGCTTCTAGAACGTCGCTACTCGACTTCTAGGTAA
TAGAAACAACAAAGCCCGCA

Product: amino acid/peptide transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 490; Mature: 489

Protein sequence:

>490_residues
MSENSQGTMLGHPKGLFLLFTTELWERFSYYAMRAILVLYLVDRVQSEGGHGLGWSQADAISLYGTFTGLVYLTPLLGGW
LADNFLGQRKAIMIGGTLMAAGQFILGTPHAWVQGMETEVFYLGLGVLILGNGLFKPNISTMVGDLYAEGDHRRDGAFTI
FYMGINVGAFLSGIIVGSVVSAYDGNFQAGFICAGIGMVLSLIIQFLFAQKLLGNIGTVPAAKLEKQKDEARGQVRKEPL
TKVERDRIKVIMVMGLFTIVFWAGFEQAGGLMNLFTNDFTDRMIGSWEVPTTWFQSLNAMFIVIFAPVVASIWVRLGDRE
PNSPVKFALGLVLLAIGFLFMIGAVVEMGGDPTAKSSMWWLVGAYFFHTMGELCLSPIGLSMVTKLAPLRIVSLMMGAWF
LFIAAANKIGGVVGSFIGHGGEKEEQLANAMSIFAGIAITAAISGVILYFMADKLVDWMHGAESKVHHTEEEALEEEIAV
TGEHEAMKRS

Sequences:

>Translated_490_residues
MSENSQGTMLGHPKGLFLLFTTELWERFSYYAMRAILVLYLVDRVQSEGGHGLGWSQADAISLYGTFTGLVYLTPLLGGW
LADNFLGQRKAIMIGGTLMAAGQFILGTPHAWVQGMETEVFYLGLGVLILGNGLFKPNISTMVGDLYAEGDHRRDGAFTI
FYMGINVGAFLSGIIVGSVVSAYDGNFQAGFICAGIGMVLSLIIQFLFAQKLLGNIGTVPAAKLEKQKDEARGQVRKEPL
TKVERDRIKVIMVMGLFTIVFWAGFEQAGGLMNLFTNDFTDRMIGSWEVPTTWFQSLNAMFIVIFAPVVASIWVRLGDRE
PNSPVKFALGLVLLAIGFLFMIGAVVEMGGDPTAKSSMWWLVGAYFFHTMGELCLSPIGLSMVTKLAPLRIVSLMMGAWF
LFIAAANKIGGVVGSFIGHGGEKEEQLANAMSIFAGIAITAAISGVILYFMADKLVDWMHGAESKVHHTEEEALEEEIAV
TGEHEAMKRS
>Mature_489_residues
SENSQGTMLGHPKGLFLLFTTELWERFSYYAMRAILVLYLVDRVQSEGGHGLGWSQADAISLYGTFTGLVYLTPLLGGWL
ADNFLGQRKAIMIGGTLMAAGQFILGTPHAWVQGMETEVFYLGLGVLILGNGLFKPNISTMVGDLYAEGDHRRDGAFTIF
YMGINVGAFLSGIIVGSVVSAYDGNFQAGFICAGIGMVLSLIIQFLFAQKLLGNIGTVPAAKLEKQKDEARGQVRKEPLT
KVERDRIKVIMVMGLFTIVFWAGFEQAGGLMNLFTNDFTDRMIGSWEVPTTWFQSLNAMFIVIFAPVVASIWVRLGDREP
NSPVKFALGLVLLAIGFLFMIGAVVEMGGDPTAKSSMWWLVGAYFFHTMGELCLSPIGLSMVTKLAPLRIVSLMMGAWFL
FIAAANKIGGVVGSFIGHGGEKEEQLANAMSIFAGIAITAAISGVILYFMADKLVDWMHGAESKVHHTEEEALEEEIAVT
GEHEAMKRS

Specific function: Unknown

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family [H]

Homologues:

Organism=Homo sapiens, GI4827008, Length=401, Percent_Identity=28.927680798005, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI226371746, Length=342, Percent_Identity=25.7309941520468, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI226371748, Length=339, Percent_Identity=23.598820058997, Blast_Score=91, Evalue=3e-18,
Organism=Escherichia coli, GI1787922, Length=496, Percent_Identity=30.4435483870968, Blast_Score=221, Evalue=1e-58,
Organism=Escherichia coli, GI1789911, Length=505, Percent_Identity=27.1287128712871, Blast_Score=195, Evalue=7e-51,
Organism=Escherichia coli, GI1790572, Length=447, Percent_Identity=30.6487695749441, Blast_Score=188, Evalue=6e-49,
Organism=Escherichia coli, GI1786927, Length=451, Percent_Identity=28.8248337028825, Blast_Score=175, Evalue=5e-45,
Organism=Caenorhabditis elegans, GI17569141, Length=389, Percent_Identity=25.1928020565553, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI71987453, Length=378, Percent_Identity=26.1904761904762, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17541704, Length=342, Percent_Identity=26.3157894736842, Blast_Score=74, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6322946, Length=510, Percent_Identity=21.9607843137255, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI28571098, Length=376, Percent_Identity=30.0531914893617, Blast_Score=118, Evalue=1e-26,
Organism=Drosophila melanogaster, GI28571102, Length=380, Percent_Identity=30, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI28571100, Length=380, Percent_Identity=30, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24639581, Length=354, Percent_Identity=27.683615819209, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24639583, Length=355, Percent_Identity=27.887323943662, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24639585, Length=346, Percent_Identity=28.0346820809249, Blast_Score=100, Evalue=4e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 53371; Mature: 53240

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: PS01022 PTR2_1 ; PS01023 PTR2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSENSQGTMLGHPKGLFLLFTTELWERFSYYAMRAILVLYLVDRVQSEGGHGLGWSQADA
CCCCCCCCEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCH
ISLYGTFTGLVYLTPLLGGWLADNFLGQRKAIMIGGTLMAAGQFILGTPHAWVQGMETEV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCHHHHCCCCEECCCHHHHCCCCCCH
FYLGLGVLILGNGLFKPNISTMVGDLYAEGDHRRDGAFTIFYMGINVGAFLSGIIVGSVV
HHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHH
SAYDGNFQAGFICAGIGMVLSLIIQFLFAQKLLGNIGTVPAAKLEKQKDEARGQVRKEPL
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
TKVERDRIKVIMVMGLFTIVFWAGFEQAGGLMNLFTNDFTDRMIGSWEVPTTWFQSLNAM
HHHHHHHHHHHHHHHHHHHHHHHCHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
FIVIFAPVVASIWVRLGDREPNSPVKFALGLVLLAIGFLFMIGAVVEMGGDPTAKSSMWW
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHH
LVGAYFFHTMGELCLSPIGLSMVTKLAPLRIVSLMMGAWFLFIAAANKIGGVVGSFIGHG
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GEKEEQLANAMSIFAGIAITAAISGVILYFMADKLVDWMHGAESKVHHTEEEALEEEIAV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCHHHHHHHHHHC
TGEHEAMKRS
CCCHHHHCCC
>Mature Secondary Structure 
SENSQGTMLGHPKGLFLLFTTELWERFSYYAMRAILVLYLVDRVQSEGGHGLGWSQADA
CCCCCCCEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCH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CCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]