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The map label for this gene is trpB [H]

Identifier: 119775268

GI number: 119775268

Start: 2578783

End: 2579976

Strand: Direct

Name: trpB [H]

Synonym: Sama_2133

Alternate gene names: 119775268

Gene position: 2578783-2579976 (Clockwise)

Preceding gene: 119775267

Following gene: 119775269

Centisome position: 59.89

GC content: 57.54

Gene sequence:

>1194_bases
ATGAGCGAGCTGAAACTCGATCCCTACTTCGGCGAATACGGCGGTATGTACGTGCCGCAAATTCTGATGCCGGCGCTGAA
GCAACTGGAGACCGCCTTTGTTGAGGCCCAGCAAGACCCAGAGTTCTTAACAGAATTCCACGACCTGTTGAAAAACTATG
CGGGCCGCCCCACCGCCTTAACCTTGACCCGTAATCTGTCTCCCAATCCCAAGGTGAAAATCTACTTAAAGCGTGAGGAC
CTGCTGCACGGCGGTGCCCACAAGACCAATCAGGTGCTAGGTCAGGCGCTGCTTGCCAAACGCATGGGCAAGAAAGAGAT
TATTGCCGAGACAGGCGCCGGGCAACACGGTGTGGCCACAGCGCTGGCTTGCGCCCTGTTGGGGCTCAAGTGCAAGGTAT
ACATGGGTGCCAAAGACGTAGCCCGCCAGAGCCCCAATGTGTTTCGTATGCGTTTGATGGGCGCGGAGGTTATCCCGGTC
ACCTCCGGCTCTGCCACCCTCAAGGATGCCTGTAACGAGGCCATGCGTGACTGGTCCGGCAGCTACGACCGCGCCCACTA
TTTGCTGGGTACTGCCGCAGGGCCTCATCCCTTCCCCACCATAGTACGGGAATTCCAGCGCATGATTGGCGCCGAAACAA
AAGCCCAAATGTTGGAGAAAGAAGGCCGCCTGCCGGATGCCGTTATCGCCTGCGTGGGTGGCGGCTCCAACGCCATCGGT
ATGTTTGCTGACTTTATCGACGAACCTTCGGTGAAGCTTATTGGGGTAGAGCCCGCTGGCAAGGGCATTGACACACCGAT
GCACGGTGCGCCGCTCAAGCATGGCAAGACGGGTATCTTCTTTGGTATGAAAGCCCCCTTGATGCAGGATGCGCATGGCC
AGATTGAAGAGTCCTACTCGATTTCTGCCGGTCTGGACTTCCCGTCCGTTGGACCCCAGCACGCCTATCTCAATGCCACC
GGCCGCGCCACCTATGAGTCGGCCACCGATGACGAAGCGCTGGAGGCATTCCAGCTGCTTGCCCGCAGCGAAGGCATTAT
CCCGGCACTGGAATCGGCTCACGCGCTGGCGTATGCACTGCGTCTGGCCAAAGACGCCACCGAAGAGCAAATCATTGTGG
TCAATCTCTCTGGCCGCGGTGATAAAGACATTTTTACCGTATCTGACATTTTAGACGGCAAGGCCAGCGCATAA

Upstream 100 bases:

>100_bases
GGCATTTGCCAGCCTTCGCAACTACTGACAAGCACTTAACCGAACAGAATTATTGGTGGTAAAGCCGCCATAGCAGATTG
ACTGACTTTGGAGAGATACA

Downstream 100 bases:

>100_bases
GGAGTACTGCCATGAACCGATATTCGAACGCCTTTGCCCGCTTAAAAGCCGGATCACGGGGCGCCTTCGTGCCTTTCGTC
ACCCTGGGTGACCCAGGCAT

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 397; Mature: 396

Protein sequence:

>397_residues
MSELKLDPYFGEYGGMYVPQILMPALKQLETAFVEAQQDPEFLTEFHDLLKNYAGRPTALTLTRNLSPNPKVKIYLKRED
LLHGGAHKTNQVLGQALLAKRMGKKEIIAETGAGQHGVATALACALLGLKCKVYMGAKDVARQSPNVFRMRLMGAEVIPV
TSGSATLKDACNEAMRDWSGSYDRAHYLLGTAAGPHPFPTIVREFQRMIGAETKAQMLEKEGRLPDAVIACVGGGSNAIG
MFADFIDEPSVKLIGVEPAGKGIDTPMHGAPLKHGKTGIFFGMKAPLMQDAHGQIEESYSISAGLDFPSVGPQHAYLNAT
GRATYESATDDEALEAFQLLARSEGIIPALESAHALAYALRLAKDATEEQIIVVNLSGRGDKDIFTVSDILDGKASA

Sequences:

>Translated_397_residues
MSELKLDPYFGEYGGMYVPQILMPALKQLETAFVEAQQDPEFLTEFHDLLKNYAGRPTALTLTRNLSPNPKVKIYLKRED
LLHGGAHKTNQVLGQALLAKRMGKKEIIAETGAGQHGVATALACALLGLKCKVYMGAKDVARQSPNVFRMRLMGAEVIPV
TSGSATLKDACNEAMRDWSGSYDRAHYLLGTAAGPHPFPTIVREFQRMIGAETKAQMLEKEGRLPDAVIACVGGGSNAIG
MFADFIDEPSVKLIGVEPAGKGIDTPMHGAPLKHGKTGIFFGMKAPLMQDAHGQIEESYSISAGLDFPSVGPQHAYLNAT
GRATYESATDDEALEAFQLLARSEGIIPALESAHALAYALRLAKDATEEQIIVVNLSGRGDKDIFTVSDILDGKASA
>Mature_396_residues
SELKLDPYFGEYGGMYVPQILMPALKQLETAFVEAQQDPEFLTEFHDLLKNYAGRPTALTLTRNLSPNPKVKIYLKREDL
LHGGAHKTNQVLGQALLAKRMGKKEIIAETGAGQHGVATALACALLGLKCKVYMGAKDVARQSPNVFRMRLMGAEVIPVT
SGSATLKDACNEAMRDWSGSYDRAHYLLGTAAGPHPFPTIVREFQRMIGAETKAQMLEKEGRLPDAVIACVGGGSNAIGM
FADFIDEPSVKLIGVEPAGKGIDTPMHGAPLKHGKTGIFFGMKAPLMQDAHGQIEESYSISAGLDFPSVGPQHAYLNATG
RATYESATDDEALEAFQLLARSEGIIPALESAHALAYALRLAKDATEEQIIVVNLSGRGDKDIFTVSDILDGKASA

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=390, Percent_Identity=79.7435897435898, Blast_Score=650, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6321412, Length=384, Percent_Identity=53.90625, Blast_Score=426, Evalue=1e-120,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 42673; Mature: 42542

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSELKLDPYFGEYGGMYVPQILMPALKQLETAFVEAQQDPEFLTEFHDLLKNYAGRPTAL
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEE
TLTRNLSPNPKVKIYLKREDLLHGGAHKTNQVLGQALLAKRMGKKEIIAETGAGQHGVAT
EEEECCCCCCCEEEEEEHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCHHHH
ALACALLGLKCKVYMGAKDVARQSPNVFRMRLMGAEVIPVTSGSATLKDACNEAMRDWSG
HHHHHHHCCEEEEEECCHHHHHCCCCCEEEEECCCEEEEECCCCHHHHHHHHHHHHHCCC
SYDRAHYLLGTAAGPHPFPTIVREFQRMIGAETKAQMLEKEGRLPDAVIACVGGGSNAIG
CCCHHEEEEECCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEEECCCCCHHH
MFADFIDEPSVKLIGVEPAGKGIDTPMHGAPLKHGKTGIFFGMKAPLMQDAHGQIEESYS
HHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHCCCCCHHHCCE
ISAGLDFPSVGPQHAYLNATGRATYESATDDEALEAFQLLARSEGIIPALESAHALAYAL
EECCCCCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
RLAKDATEEQIIVVNLSGRGDKDIFTVSDILDGKASA
HHHHCCCCCEEEEEEECCCCCCCEEEHHHHCCCCCCC
>Mature Secondary Structure 
SELKLDPYFGEYGGMYVPQILMPALKQLETAFVEAQQDPEFLTEFHDLLKNYAGRPTAL
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCEEE
TLTRNLSPNPKVKIYLKREDLLHGGAHKTNQVLGQALLAKRMGKKEIIAETGAGQHGVAT
EEEECCCCCCCEEEEEEHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCHHHH
ALACALLGLKCKVYMGAKDVARQSPNVFRMRLMGAEVIPVTSGSATLKDACNEAMRDWSG
HHHHHHHCCEEEEEECCHHHHHCCCCCEEEEECCCEEEEECCCCHHHHHHHHHHHHHCCC
SYDRAHYLLGTAAGPHPFPTIVREFQRMIGAETKAQMLEKEGRLPDAVIACVGGGSNAIG
CCCHHEEEEECCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEEEECCCCCHHH
MFADFIDEPSVKLIGVEPAGKGIDTPMHGAPLKHGKTGIFFGMKAPLMQDAHGQIEESYS
HHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCEEEECCCCCHHHCCCCCHHHCCE
ISAGLDFPSVGPQHAYLNATGRATYESATDDEALEAFQLLARSEGIIPALESAHALAYAL
EECCCCCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
RLAKDATEEQIIVVNLSGRGDKDIFTVSDILDGKASA
HHHHCCCCCEEEEEEECCCCCCCEEEHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA