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The map label for this gene is nagD [H]

Identifier: 119775234

GI number: 119775234

Start: 2543313

End: 2544059

Strand: Direct

Name: nagD [H]

Synonym: Sama_2099

Alternate gene names: 119775234

Gene position: 2543313-2544059 (Clockwise)

Preceding gene: 119775233

Following gene: 119775235

Centisome position: 59.06

GC content: 53.15

Gene sequence:

>747_bases
ATGAAAAACATCATCTGTGATATCGACGGAGTACTGCTGCACGACAACAAACTGGTGCCCGGCAGCGACAAATTTATTCA
TCGGGTGCTGGAACAAGGCAACCCCTTGGTTATCCTGACTAATTACCCGGTACAAACCGGCAAAGATCTGCAAAACCGCC
TCGATGCCGCGGGCATTAACGTCCCCGAGGAATGTTTTTACACCGCCGCCATGGCCACCGCCGACTTTTTGAAACATCAG
GAAGGCAGCAAAGCCTTTGTGATTGGCGAAGGCGCTCTCACCCACGAACTCTACAAGGCCGGTTTTACCATCACCGACAT
CAACCCCGACTTTGTGATTGTGGGTGAAACCCGCTCTTACAACTGGGATATGATCCATAAAGCGGCACGGTTTGTAGCCG
ATGGCGCCCGCTTTATTGCCACCAATCCAGATACCCATGGCCCGGCATTTTCACCGGCTTGTGGCGCCCTGTGCGCGCCC
ATTGAGCGGATCACCGGCCGCAAACCCTTTTACGTGGGTAAACCCAGCAGCTGGATAGTGCGTTCGGCCTTAAACCACAT
CAACGGCCACTCGGAAAACACGGTTATCATTGGCGATAATATGCGCACCGACATTCTGGCCGGTTTCCAGGCGGGCCTTG
AGACCATACTGGTACTCACTGGCGTGAGCCGTCTTGAGGACATAGAGAAAGAGCCGTTCAGGCCCAATCATGTGTTTAAT
TGTGCCGGTGACATCGATATTTTCTGA

Upstream 100 bases:

>100_bases
AACTCGCTCTGTTATCGTTGAATTTGCCGCCGATTTGGCTTTAGATAATGAGGCCGTCCATTCTTTTCGCCAGCGACGGA
ACCTTGAACAGGATTTTTCA

Downstream 100 bases:

>100_bases
TCCGCACCAACGCCTGCACGATATCACTTTCCCAAATGTGTGAACGTGCGTGTCAGCCCAAGTGCATTCACCCAGGGTAT
GTTCACAAATTGACACATAA

Product: UMP phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MKNIICDIDGVLLHDNKLVPGSDKFIHRVLEQGNPLVILTNYPVQTGKDLQNRLDAAGINVPEECFYTAAMATADFLKHQ
EGSKAFVIGEGALTHELYKAGFTITDINPDFVIVGETRSYNWDMIHKAARFVADGARFIATNPDTHGPAFSPACGALCAP
IERITGRKPFYVGKPSSWIVRSALNHINGHSENTVIIGDNMRTDILAGFQAGLETILVLTGVSRLEDIEKEPFRPNHVFN
CAGDIDIF

Sequences:

>Translated_248_residues
MKNIICDIDGVLLHDNKLVPGSDKFIHRVLEQGNPLVILTNYPVQTGKDLQNRLDAAGINVPEECFYTAAMATADFLKHQ
EGSKAFVIGEGALTHELYKAGFTITDINPDFVIVGETRSYNWDMIHKAARFVADGARFIATNPDTHGPAFSPACGALCAP
IERITGRKPFYVGKPSSWIVRSALNHINGHSENTVIIGDNMRTDILAGFQAGLETILVLTGVSRLEDIEKEPFRPNHVFN
CAGDIDIF
>Mature_248_residues
MKNIICDIDGVLLHDNKLVPGSDKFIHRVLEQGNPLVILTNYPVQTGKDLQNRLDAAGINVPEECFYTAAMATADFLKHQ
EGSKAFVIGEGALTHELYKAGFTITDINPDFVIVGETRSYNWDMIHKAARFVADGARFIATNPDTHGPAFSPACGALCAP
IERITGRKPFYVGKPSSWIVRSALNHINGHSENTVIIGDNMRTDILAGFQAGLETILVLTGVSRLEDIEKEPFRPNHVFN
CAGDIDIF

Specific function: Unknown

COG id: COG0647

COG function: function code G; Predicted sugar phosphatases of the HAD superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI10092677, Length=250, Percent_Identity=26.8, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI108796653, Length=262, Percent_Identity=29.0076335877863, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI14149777, Length=236, Percent_Identity=26.271186440678, Blast_Score=80, Evalue=2e-15,
Organism=Escherichia coli, GI1786890, Length=247, Percent_Identity=71.6599190283401, Blast_Score=391, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI17562458, Length=286, Percent_Identity=27.2727272727273, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17560956, Length=286, Percent_Identity=27.2727272727273, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17558880, Length=281, Percent_Identity=27.0462633451957, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71984613, Length=265, Percent_Identity=25.6603773584906, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI193210059, Length=258, Percent_Identity=25.968992248062, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17557870, Length=253, Percent_Identity=25.296442687747, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17562356, Length=231, Percent_Identity=24.6753246753247, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319965, Length=234, Percent_Identity=24.3589743589744, Blast_Score=74, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24666141, Length=254, Percent_Identity=29.1338582677165, Blast_Score=104, Evalue=6e-23,
Organism=Drosophila melanogaster, GI24656326, Length=254, Percent_Identity=24.0157480314961, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24656330, Length=251, Percent_Identity=26.2948207171315, Blast_Score=76, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006357
- InterPro:   IPR023215 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: NA

Molecular weight: Translated: 27207; Mature: 27207

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNIICDIDGVLLHDNKLVPGSDKFIHRVLEQGNPLVILTNYPVQTGKDLQNRLDAAGIN
CCCEEEECCCEEEECCEECCCCHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHCCCC
VPEECFYTAAMATADFLKHQEGSKAFVIGEGALTHELYKAGFTITDINPDFVIVGETRSY
CCHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHCCCEEEECCCCEEEEECCCCC
NWDMIHKAARFVADGARFIATNPDTHGPAFSPACGALCAPIERITGRKPFYVGKPSSWIV
CHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCEEECCCHHHHH
RSALNHINGHSENTVIIGDNMRTDILAGFQAGLETILVLTGVSRLEDIEKEPFRPNHVFN
HHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCEEE
CAGDIDIF
CCCCCCCC
>Mature Secondary Structure
MKNIICDIDGVLLHDNKLVPGSDKFIHRVLEQGNPLVILTNYPVQTGKDLQNRLDAAGIN
CCCEEEECCCEEEECCEECCCCHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHCCCC
VPEECFYTAAMATADFLKHQEGSKAFVIGEGALTHELYKAGFTITDINPDFVIVGETRSY
CCHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHCCCEEEECCCCEEEEECCCCC
NWDMIHKAARFVADGARFIATNPDTHGPAFSPACGALCAPIERITGRKPFYVGKPSSWIV
CHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCEEECCCHHHHH
RSALNHINGHSENTVIIGDNMRTDILAGFQAGLETILVLTGVSRLEDIEKEPFRPNHVFN
HHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCEEE
CAGDIDIF
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]