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The map label for this gene is hdfR [H]

Identifier: 119775132

GI number: 119775132

Start: 2427012

End: 2427884

Strand: Reverse

Name: hdfR [H]

Synonym: Sama_1997

Alternate gene names: 119775132

Gene position: 2427884-2427012 (Counterclockwise)

Preceding gene: 119775137

Following gene: 119775130

Centisome position: 56.38

GC content: 53.38

Gene sequence:

>873_bases
ATGGACACAGATCTGCTGAAAACCTTTTTGGAAGTTTCACGTACCCGCCATTTCGGAAAAGCTGCCGAAAATCTTTATCT
TACCCGAAGCGCAGTCAGTTTTCGGGTGAAGCAGCTTGAAACGATACTCGGGGTGGAGCTGTTTGAGCGCCAACGGAACA
ATATTCAGCCAACACCGGCTGGCGAGCGCATGCTGAATCATGCCGAGGCTGTGCTGACGGCTTGGGAGCGTGCGAAGCAG
GACGTGTCATTAAGTCGATTACAATCGACACAATTGACCATAGGTGCTGGCCCCAATATCTGGGATGCGTTTTTACAGGG
CAACCTGCAATCCTTGCACAAGGGCTTGCCGGGCGTGGCGTTACGCACCGAGGTGTTGCCCCAGAACGTGATGACCCGTC
AGTTGATGGAGCGCACCCTGGACATGGCGATTTCCTTCGACCCGCCCAAAATGGAGGATTTTGAACAGATCCGTATCGGC
GTGGTGCAGTTGTGGCTGGTGTCCAGTATCGGACCACTCAGTTTGTCAGAGTGTCTTAAACACCATTACATAAAGGTTGA
CTGGGGTACTGCCTTTAATATCCTTCACGCACAGGAATTTGGCGATATGCCATTGCCGGTGTTGCACACCAGTTCATCGC
GTATAGCCCTGGATTTTGTGCTCAATAACGGCGGCAGTGCGTTTTTGCCGGATCACATGGTGAGCCCGTATCTCGAGCGG
GGCGAGTTATGCCGGGTGGAAGGTGCACGCTCCATCCCCCGTAACGTGTATGTCGTGTATTGGTCGCAAAATGACAGACT
ATCGCAAATAGAGCGGGCGGTGAGTTTTCTGGCGCGGGAGTCTGATGAAGGCGCTGAAGAGCTCAGCGCCTGA

Upstream 100 bases:

>100_bases
ATGATTACCTAAGCTGTGGGATAATTTGCAACTGGAGTATTGGCTAGTATCCTTGAATTAGGAATCAAAAAATTTTGGTC
TTGTTGGTCAAAGAAATTTT

Downstream 100 bases:

>100_bases
GTAAAAAAGCGCAGCAATTACCAGAGCAGCGGCAGCAGGATAAAGGCCCACACCAGGGCGCACAGTGCCAGGCTCATAAA
CACGGCTGCTGAGGCTATGT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: H-NS-dependent flhDC regulator [H]

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MDTDLLKTFLEVSRTRHFGKAAENLYLTRSAVSFRVKQLETILGVELFERQRNNIQPTPAGERMLNHAEAVLTAWERAKQ
DVSLSRLQSTQLTIGAGPNIWDAFLQGNLQSLHKGLPGVALRTEVLPQNVMTRQLMERTLDMAISFDPPKMEDFEQIRIG
VVQLWLVSSIGPLSLSECLKHHYIKVDWGTAFNILHAQEFGDMPLPVLHTSSSRIALDFVLNNGGSAFLPDHMVSPYLER
GELCRVEGARSIPRNVYVVYWSQNDRLSQIERAVSFLARESDEGAEELSA

Sequences:

>Translated_290_residues
MDTDLLKTFLEVSRTRHFGKAAENLYLTRSAVSFRVKQLETILGVELFERQRNNIQPTPAGERMLNHAEAVLTAWERAKQ
DVSLSRLQSTQLTIGAGPNIWDAFLQGNLQSLHKGLPGVALRTEVLPQNVMTRQLMERTLDMAISFDPPKMEDFEQIRIG
VVQLWLVSSIGPLSLSECLKHHYIKVDWGTAFNILHAQEFGDMPLPVLHTSSSRIALDFVLNNGGSAFLPDHMVSPYLER
GELCRVEGARSIPRNVYVVYWSQNDRLSQIERAVSFLARESDEGAEELSA
>Mature_290_residues
MDTDLLKTFLEVSRTRHFGKAAENLYLTRSAVSFRVKQLETILGVELFERQRNNIQPTPAGERMLNHAEAVLTAWERAKQ
DVSLSRLQSTQLTIGAGPNIWDAFLQGNLQSLHKGLPGVALRTEVLPQNVMTRQLMERTLDMAISFDPPKMEDFEQIRIG
VVQLWLVSSIGPLSLSECLKHHYIKVDWGTAFNILHAQEFGDMPLPVLHTSSSRIALDFVLNNGGSAFLPDHMVSPYLER
GELCRVEGARSIPRNVYVVYWSQNDRLSQIERAVSFLARESDEGAEELSA

Specific function: Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994962, Length=269, Percent_Identity=38.2899628252788, Blast_Score=178, Evalue=3e-46,
Organism=Escherichia coli, GI1788626, Length=275, Percent_Identity=27.2727272727273, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI157672245, Length=195, Percent_Identity=28.2051282051282, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020890
- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32701; Mature: 32701

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTDLLKTFLEVSRTRHFGKAAENLYLTRSAVSFRVKQLETILGVELFERQRNNIQPTPA
CCHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GERMLNHAEAVLTAWERAKQDVSLSRLQSTQLTIGAGPNIWDAFLQGNLQSLHKGLPGVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCHHHHHHHHCCHHHHHCCCCCCC
LRTEVLPQNVMTRQLMERTLDMAISFDPPKMEDFEQIRIGVVQLWLVSSIGPLSLSECLK
HHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
HHYIKVDWGTAFNILHAQEFGDMPLPVLHTSSSRIALDFVLNNGGSAFLPDHMVSPYLER
HCEEEEECCCHHHHEEHHHCCCCCCCEEECCCCCEEEEEEEECCCCCCCCHHHHCHHHHC
GELCRVEGARSIPRNVYVVYWSQNDRLSQIERAVSFLARESDEGAEELSA
CCEEECCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCHHHHCC
>Mature Secondary Structure
MDTDLLKTFLEVSRTRHFGKAAENLYLTRSAVSFRVKQLETILGVELFERQRNNIQPTPA
CCHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GERMLNHAEAVLTAWERAKQDVSLSRLQSTQLTIGAGPNIWDAFLQGNLQSLHKGLPGVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCHHHHHHHHCCHHHHHCCCCCCC
LRTEVLPQNVMTRQLMERTLDMAISFDPPKMEDFEQIRIGVVQLWLVSSIGPLSLSECLK
HHHHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
HHYIKVDWGTAFNILHAQEFGDMPLPVLHTSSSRIALDFVLNNGGSAFLPDHMVSPYLER
HCEEEEECCCHHHHEEHHHCCCCCCCEEECCCCCEEEEEEEECCCCCCCCHHHHCHHHHC
GELCRVEGARSIPRNVYVVYWSQNDRLSQIERAVSFLARESDEGAEELSA
CCEEECCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA