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The map label for this gene is speA

Identifier: 119775098

GI number: 119775098

Start: 2391322

End: 2393232

Strand: Reverse

Name: speA

Synonym: Sama_1963

Alternate gene names: 119775098

Gene position: 2393232-2391322 (Counterclockwise)

Preceding gene: 119775099

Following gene: 119775097

Centisome position: 55.58

GC content: 53.69

Gene sequence:

>1911_bases
ATGAACGAATGGTCAATTGACGACGCCCGCGCCGGGTACAACGTTGCCCACTGGAGTCAGGGTTTTTATGGGATCAGCGA
CGAGGGTGAGGTAACCGTCTCCCCGGATCCTAAAAATCCCACCTTCAAAATTGGTTTGAACGCGCTGGCCAAGGATATGG
TTAAAGCCGGTGTGAGTTTGCCAGTGTTGGTGCGTTTCCCGCAAATTCTGCACCACAGAGTTGATCACCTGTGCCAGATG
TTCAATCAGGCCATTCAGAAATACGAGTATCAATCTGACTACCTGCTGGTGTACCCCATCAAGGTAAACCAACAGCAGAC
CGTGGTTGAGGAAATCCTCGCAAGCCAGGTAAGCAAGACTGTGCCTCAGCTGGGTCTTGAGGCTGGCAGTAAGCCTGAGC
TGATGGCTGTGCTTGCCATGGCGCAAAAGGCCAGTTCAGTAATCGTGTGTAACGGTTACAAAGACAAAGAATACATTCGC
CTGGCGCTGATTGGTGAGAAACTCGGCCACAGTGTATACATAGTGCTCGAGAAGATGTCCGAGCTGCAGATGGTGCTCGA
AGAGTCCAAGAAGCTGGGTGTTACCCCACGCCTGGGTCTGCGCGCCCGTTTGGCTTTTCAGGGCAAGGGTAAGTGGCAGG
CCAGCGGCGGTGAAAAGTCCAAGTTTGGTCTGTCTGCTGCGCAAATCTTAAAGGTCGTCGAGCGTCTGAAAGATGAAGAC
ATGCTGGAATCGCTGCAGTTGCTGCACTTCCACCTGGGTTCGCAAATCGCCAACATCCGTGATATTCGCCACGGTGTAGG
TGAGGCCGCACGTTTCTACTGTGAACTGCGTAAACTGGGCGCCAAGGTTAACTGCTTTGACGTGGGCGGCGGCTTGGCCG
TGGATTACGACGGTACCCGCAGTCAGTCAAACAACTCCATGAACTACGCGCTGGCAGAATACGCCAACAACATCGTATCT
GTGCTCACCGATGTGTGTAATCAGAACGAACAGCCAATGCCGCGCATTATTTCTGAGTCAGGCCGTTACCTCACTGCCCA
CCACGCGGTACTCATCACCGACGTGATTGGCACCGAGGCATACAGCCCGGAAGACATTCCTGCGCCGGAAGAAGAAGCGC
CTCAGCTGCTGCACAACATGTGGCGTAGCTGGAATGAAATCAGCTCACGTCTCGATCAGCGTGCTCTGATTGAAATCTTC
CACGATACTCAGTCTGATCTGGCCGAGGCCCAATCCCTCTTTGCGTTGGGACAGCTGAGCCTGGAAGACCGCGCCTGGGC
CGAGCAGTGTAACCTTGCTGTGTGTCACGAGTTGCAGGGCTTGATGAACGCCCGTAACCGTTATCAGCGCCCGATCATCG
ATGAACTGAACGAGAAACTGGCTGACAGATTCTTTGTTAACTTCTCCTTATTCCAGTCACTGCCCGATGCCTGGGGTATC
GACCAGGTATTCCCTGTGCTGCCGCTGTCAGGTTTGGACAAGGTGCCTGAGCGCCGTGCTGTGATGCTGGATATCACCTG
TGACTCAGACGGTATTGTTGACCAATACGTAGATGGTCAGGGTATTGAAACCACGCTGCCGGTACCTAACTGGTCAGCTG
AAGATCCGTATCTGATTGGCTTCTTCCTGGTGGGTGCTTATCAGGAAATCCTCGGCGACCTGCACAACCTCTTTGGTGAT
ACCAACTCAGCAGTGGTGCGTATCGACGAAGAAGGCCAGACCAATATCGAGTCTGTACTTGCCGGTGATACGGTAGCCGA
CGTACTGCGCTATGTGAACCTCGATGCCGTGTCCTTCATGCGCACCTACGAGGAGCTGGTGAATTCACACATCGCAGAAG
ACGAGCGCGCGATGATCCTCGAAGAACTCCAGGTGGGCCTCAAGGGCTACACCTATCTGGAAGACTTTTAA

Upstream 100 bases:

>100_bases
CATCAGGCAAGCTTTGCCTTGCCTAAATACGTCGAACAGGCGATCCGGTCAGCCATGACCGTGACCGCTTAATATCTCTC
TATATATAGGCACAATTGAG

Downstream 100 bases:

>100_bases
CCCATACTAAGGCAAGGTGAAGCCAGGCCGGGGAACCAGGGCGTAAGCCCTCCCGGCCCTCAGGTAGAGAAAAATGTTTT
TTGAAGGTTCAGAAAAAAAA

Product: arginine decarboxylase

Products: NA

Alternate protein names: ADC

Number of amino acids: Translated: 636; Mature: 636

Protein sequence:

>636_residues
MNEWSIDDARAGYNVAHWSQGFYGISDEGEVTVSPDPKNPTFKIGLNALAKDMVKAGVSLPVLVRFPQILHHRVDHLCQM
FNQAIQKYEYQSDYLLVYPIKVNQQQTVVEEILASQVSKTVPQLGLEAGSKPELMAVLAMAQKASSVIVCNGYKDKEYIR
LALIGEKLGHSVYIVLEKMSELQMVLEESKKLGVTPRLGLRARLAFQGKGKWQASGGEKSKFGLSAAQILKVVERLKDED
MLESLQLLHFHLGSQIANIRDIRHGVGEAARFYCELRKLGAKVNCFDVGGGLAVDYDGTRSQSNNSMNYALAEYANNIVS
VLTDVCNQNEQPMPRIISESGRYLTAHHAVLITDVIGTEAYSPEDIPAPEEEAPQLLHNMWRSWNEISSRLDQRALIEIF
HDTQSDLAEAQSLFALGQLSLEDRAWAEQCNLAVCHELQGLMNARNRYQRPIIDELNEKLADRFFVNFSLFQSLPDAWGI
DQVFPVLPLSGLDKVPERRAVMLDITCDSDGIVDQYVDGQGIETTLPVPNWSAEDPYLIGFFLVGAYQEILGDLHNLFGD
TNSAVVRIDEEGQTNIESVLAGDTVADVLRYVNLDAVSFMRTYEELVNSHIAEDERAMILEELQVGLKGYTYLEDF

Sequences:

>Translated_636_residues
MNEWSIDDARAGYNVAHWSQGFYGISDEGEVTVSPDPKNPTFKIGLNALAKDMVKAGVSLPVLVRFPQILHHRVDHLCQM
FNQAIQKYEYQSDYLLVYPIKVNQQQTVVEEILASQVSKTVPQLGLEAGSKPELMAVLAMAQKASSVIVCNGYKDKEYIR
LALIGEKLGHSVYIVLEKMSELQMVLEESKKLGVTPRLGLRARLAFQGKGKWQASGGEKSKFGLSAAQILKVVERLKDED
MLESLQLLHFHLGSQIANIRDIRHGVGEAARFYCELRKLGAKVNCFDVGGGLAVDYDGTRSQSNNSMNYALAEYANNIVS
VLTDVCNQNEQPMPRIISESGRYLTAHHAVLITDVIGTEAYSPEDIPAPEEEAPQLLHNMWRSWNEISSRLDQRALIEIF
HDTQSDLAEAQSLFALGQLSLEDRAWAEQCNLAVCHELQGLMNARNRYQRPIIDELNEKLADRFFVNFSLFQSLPDAWGI
DQVFPVLPLSGLDKVPERRAVMLDITCDSDGIVDQYVDGQGIETTLPVPNWSAEDPYLIGFFLVGAYQEILGDLHNLFGD
TNSAVVRIDEEGQTNIESVLAGDTVADVLRYVNLDAVSFMRTYEELVNSHIAEDERAMILEELQVGLKGYTYLEDF
>Mature_636_residues
MNEWSIDDARAGYNVAHWSQGFYGISDEGEVTVSPDPKNPTFKIGLNALAKDMVKAGVSLPVLVRFPQILHHRVDHLCQM
FNQAIQKYEYQSDYLLVYPIKVNQQQTVVEEILASQVSKTVPQLGLEAGSKPELMAVLAMAQKASSVIVCNGYKDKEYIR
LALIGEKLGHSVYIVLEKMSELQMVLEESKKLGVTPRLGLRARLAFQGKGKWQASGGEKSKFGLSAAQILKVVERLKDED
MLESLQLLHFHLGSQIANIRDIRHGVGEAARFYCELRKLGAKVNCFDVGGGLAVDYDGTRSQSNNSMNYALAEYANNIVS
VLTDVCNQNEQPMPRIISESGRYLTAHHAVLITDVIGTEAYSPEDIPAPEEEAPQLLHNMWRSWNEISSRLDQRALIEIF
HDTQSDLAEAQSLFALGQLSLEDRAWAEQCNLAVCHELQGLMNARNRYQRPIIDELNEKLADRFFVNFSLFQSLPDAWGI
DQVFPVLPLSGLDKVPERRAVMLDITCDSDGIVDQYVDGQGIETTLPVPNWSAEDPYLIGFFLVGAYQEILGDLHNLFGD
TNSAVVRIDEEGQTNIESVLAGDTVADVLRYVNLDAVSFMRTYEELVNSHIAEDERAMILEELQVGLKGYTYLEDF

Specific function: Catalyzes the biosynthesis of agmatine from arginine

COG id: COG1166

COG function: function code E; Arginine decarboxylase (spermidine biosynthesis)

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-II family. SpeA subfamily

Homologues:

Organism=Escherichia coli, GI1789307, Length=624, Percent_Identity=55.6089743589744, Blast_Score=720, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SPEA_SHEAM (A1S712)

Other databases:

- EMBL:   CP000507
- RefSeq:   YP_927838.1
- ProteinModelPortal:   A1S712
- STRING:   A1S712
- GeneID:   4604213
- GenomeReviews:   CP000507_GR
- KEGG:   saz:Sama_1963
- NMPDR:   fig|326297.7.peg.1843
- eggNOG:   COG1166
- HOGENOM:   HBG321436
- OMA:   TCDSDGE
- PhylomeDB:   A1S712
- ProtClustDB:   PRK05354
- HAMAP:   MF_01417
- InterPro:   IPR009006
- InterPro:   IPR002985
- InterPro:   IPR022643
- InterPro:   IPR022644
- InterPro:   IPR000183
- Gene3D:   G3DSA:2.40.37.10
- PANTHER:   PTHR11482:SF3
- PIRSF:   PIRSF001336
- PRINTS:   PR01180
- PRINTS:   PR01179
- TIGRFAMs:   TIGR01273

Pfam domain/function: PF02784 Orn_Arg_deC_N; PF00278 Orn_DAP_Arg_deC

EC number: =4.1.1.19

Molecular weight: Translated: 71126; Mature: 71126

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: PS00878 ODR_DC_2_1; PS00879 ODR_DC_2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEWSIDDARAGYNVAHWSQGFYGISDEGEVTVSPDPKNPTFKIGLNALAKDMVKAGVSL
CCCCCCCHHHCCCCHHHCCCCCCCCCCCCCEEECCCCCCCEEEECHHHHHHHHHHCCCCC
PVLVRFPQILHHRVDHLCQMFNQAIQKYEYQSDYLLVYPIKVNQQQTVVEEILASQVSKT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHH
VPQLGLEAGSKPELMAVLAMAQKASSVIVCNGYKDKEYIRLALIGEKLGHSVYIVLEKMS
HHHHHCCCCCCHHHHHHHHHHHHCCCEEEECCCCCCHHEEEEEEHHHHCCEEEHHHHHHH
ELQMVLEESKKLGVTPRLGLRARLAFQGKGKWQASGGEKSKFGLSAAQILKVVERLKDED
HHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEECCCCCCCCCCCCHHHHHHHHHHHCCHH
MLESLQLLHFHLGSQIANIRDIRHGVGEAARFYCELRKLGAKVNCFDVGGGLAVDYDGTR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCEEECCCCCC
SQSNNSMNYALAEYANNIVSVLTDVCNQNEQPMPRIISESGRYLTAHHAVLITDVIGTEA
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCEEEECHHEEEEHHHCCCC
YSPEDIPAPEEEAPQLLHNMWRSWNEISSRLDQRALIEIFHDTQSDLAEAQSLFALGQLS
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCC
LEDRAWAEQCNLAVCHELQGLMNARNRYQRPIIDELNEKLADRFFVNFSLFQSLPDAWGI
CHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
DQVFPVLPLSGLDKVPERRAVMLDITCDSDGIVDQYVDGQGIETTLPVPNWSAEDPYLIG
HHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCHHHCCCCCCCEEECCCCCCCCCCCEEHH
FFLVGAYQEILGDLHNLFGDTNSAVVRIDEEGQTNIESVLAGDTVADVLRYVNLDAVSFM
HHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHCCCHHHHHHHHHCHHHHHHH
RTYEELVNSHIAEDERAMILEELQVGLKGYTYLEDF
HHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHCCC
>Mature Secondary Structure
MNEWSIDDARAGYNVAHWSQGFYGISDEGEVTVSPDPKNPTFKIGLNALAKDMVKAGVSL
CCCCCCCHHHCCCCHHHCCCCCCCCCCCCCEEECCCCCCCEEEECHHHHHHHHHHCCCCC
PVLVRFPQILHHRVDHLCQMFNQAIQKYEYQSDYLLVYPIKVNQQQTVVEEILASQVSKT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHH
VPQLGLEAGSKPELMAVLAMAQKASSVIVCNGYKDKEYIRLALIGEKLGHSVYIVLEKMS
HHHHHCCCCCCHHHHHHHHHHHHCCCEEEECCCCCCHHEEEEEEHHHHCCEEEHHHHHHH
ELQMVLEESKKLGVTPRLGLRARLAFQGKGKWQASGGEKSKFGLSAAQILKVVERLKDED
HHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEECCCCCCCCCCCCHHHHHHHHHHHCCHH
MLESLQLLHFHLGSQIANIRDIRHGVGEAARFYCELRKLGAKVNCFDVGGGLAVDYDGTR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCEEECCCCCC
SQSNNSMNYALAEYANNIVSVLTDVCNQNEQPMPRIISESGRYLTAHHAVLITDVIGTEA
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCEEEECHHEEEEHHHCCCC
YSPEDIPAPEEEAPQLLHNMWRSWNEISSRLDQRALIEIFHDTQSDLAEAQSLFALGQLS
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCC
LEDRAWAEQCNLAVCHELQGLMNARNRYQRPIIDELNEKLADRFFVNFSLFQSLPDAWGI
CHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
DQVFPVLPLSGLDKVPERRAVMLDITCDSDGIVDQYVDGQGIETTLPVPNWSAEDPYLIG
HHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCHHHCCCCCCCEEECCCCCCCCCCCEEHH
FFLVGAYQEILGDLHNLFGDTNSAVVRIDEEGQTNIESVLAGDTVADVLRYVNLDAVSFM
HHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHCCCHHHHHHHHHCHHHHHHH
RTYEELVNSHIAEDERAMILEELQVGLKGYTYLEDF
HHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA