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The map label for this gene is pdxH

Identifier: 119775096

GI number: 119775096

Start: 2389402

End: 2390040

Strand: Reverse

Name: pdxH

Synonym: Sama_1961

Alternate gene names: 119775096

Gene position: 2390040-2389402 (Counterclockwise)

Preceding gene: 119775097

Following gene: 119775094

Centisome position: 55.5

GC content: 56.03

Gene sequence:

>639_bases
ATGACAGATCTCAGCGACATTCGCCGTGAATACACCAAAGGCGGCCTCAGGCGCAGCGAATTGCCCGAAGACCCCATGGC
ATTGTTTGAGCGCTGGATGGAGCAGGCCAAGGCCGCAGAGCTTACCGACCCCACGGCCATGTGTGTGGCGACAGTCGATG
AGCTAGGCCAACCCTATCAACGGATAGTGCTTCTCAAACGCTTCGACGAGCAGGGTTTTGTATTTTTCACCAATCTGGGT
AGCCGCAAGGCGACTCAACTGAAGCATAACGCCCACATCAGCTTGCTCTTTCCCTGGCACCCTCTGGAGCGACAGGTGGC
TGTGACAGGCATTGCCGAACCACTTTCAACGGCTGAGGTACTCAAGTACTTCGTTACCCGACCGAAAGACAGCCAGATTG
CAGCCTGGGTATCTGCTCAGTCATCCAAACTCAGTGCCAGGCAGGTCCTGGAAGCCAAGTTTATGGAGATGAAGCAGAAG
TTTTCCGCCGGTGAAGTGCCATTGCCATCTTTCTGGGGCGGCTATCTGGTCCGTCCCGCCAGTATTGAGTTCTGGCAGGG
CGGGGAACACAGGCTGCACGACCGCTTTATTTATGAAAAAACGGCGGCGGGTTGGGATATTGAGCGCCTGGCGCCCTGA

Upstream 100 bases:

>100_bases
TTGGCGGATAAAATCAAAAGCCGACCTCACTGTCGGCTTTTTTGTTGCACGTCAAGCGGCTAGAATGCCTCAAACGATAC
AGTGCCCATAAGGAATCACC

Downstream 100 bases:

>100_bases
TCACAGTGGCGTGACGTTTGCTGCCAGGAGGCCCTTTTGGCCTTCAACCAGGCTGAAGCTGACTTTTTGACCTTCTTTTA
AAGTGCGTCTTCCCTGAGTA

Product: pyridoxamine 5'-phosphate oxidase

Products: NA

Alternate protein names: PNP/PMP oxidase; PNPOx; Pyridoxal 5'-phosphate synthase

Number of amino acids: Translated: 212; Mature: 211

Protein sequence:

>212_residues
MTDLSDIRREYTKGGLRRSELPEDPMALFERWMEQAKAAELTDPTAMCVATVDELGQPYQRIVLLKRFDEQGFVFFTNLG
SRKATQLKHNAHISLLFPWHPLERQVAVTGIAEPLSTAEVLKYFVTRPKDSQIAAWVSAQSSKLSARQVLEAKFMEMKQK
FSAGEVPLPSFWGGYLVRPASIEFWQGGEHRLHDRFIYEKTAAGWDIERLAP

Sequences:

>Translated_212_residues
MTDLSDIRREYTKGGLRRSELPEDPMALFERWMEQAKAAELTDPTAMCVATVDELGQPYQRIVLLKRFDEQGFVFFTNLG
SRKATQLKHNAHISLLFPWHPLERQVAVTGIAEPLSTAEVLKYFVTRPKDSQIAAWVSAQSSKLSARQVLEAKFMEMKQK
FSAGEVPLPSFWGGYLVRPASIEFWQGGEHRLHDRFIYEKTAAGWDIERLAP
>Mature_211_residues
TDLSDIRREYTKGGLRRSELPEDPMALFERWMEQAKAAELTDPTAMCVATVDELGQPYQRIVLLKRFDEQGFVFFTNLGS
RKATQLKHNAHISLLFPWHPLERQVAVTGIAEPLSTAEVLKYFVTRPKDSQIAAWVSAQSSKLSARQVLEAKFMEMKQKF
SAGEVPLPSFWGGYLVRPASIEFWQGGEHRLHDRFIYEKTAAGWDIERLAP

Specific function: Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP)

COG id: COG0259

COG function: function code H; Pyridoxamine-phosphate oxidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxamine 5'-phosphate oxidase family

Homologues:

Organism=Homo sapiens, GI8922498, Length=229, Percent_Identity=40.6113537117904, Blast_Score=157, Evalue=8e-39,
Organism=Escherichia coli, GI1787926, Length=212, Percent_Identity=67.9245283018868, Blast_Score=312, Evalue=1e-86,
Organism=Caenorhabditis elegans, GI17553712, Length=220, Percent_Identity=35.9090909090909, Blast_Score=132, Evalue=9e-32,
Organism=Saccharomyces cerevisiae, GI6319509, Length=209, Percent_Identity=37.799043062201, Blast_Score=146, Evalue=3e-36,
Organism=Drosophila melanogaster, GI24644901, Length=207, Percent_Identity=42.9951690821256, Blast_Score=162, Evalue=2e-40,
Organism=Drosophila melanogaster, GI45551845, Length=207, Percent_Identity=42.9951690821256, Blast_Score=162, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24644903, Length=188, Percent_Identity=30.3191489361702, Blast_Score=100, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PDXH_SHEAM (A1S710)

Other databases:

- EMBL:   CP000507
- RefSeq:   YP_927836.1
- ProteinModelPortal:   A1S710
- SMR:   A1S710
- STRING:   A1S710
- GeneID:   4604211
- GenomeReviews:   CP000507_GR
- KEGG:   saz:Sama_1961
- NMPDR:   fig|326297.7.peg.1841
- eggNOG:   COG0259
- HOGENOM:   HBG327559
- OMA:   FTFFTNY
- PhylomeDB:   A1S710
- ProtClustDB:   PRK05679
- HAMAP:   MF_01629
- InterPro:   IPR000659
- InterPro:   IPR019740
- InterPro:   IPR019576
- InterPro:   IPR011576
- InterPro:   IPR012349
- InterPro:   IPR009002
- Gene3D:   G3DSA:2.30.110.10
- PANTHER:   PTHR10851
- PIRSF:   PIRSF000190
- TIGRFAMs:   TIGR00558

Pfam domain/function: PF10590 PNPOx_C; PF01243 Pyridox_oxidase; SSF50475 FMN_binding

EC number: =1.4.3.5

Molecular weight: Translated: 24230; Mature: 24099

Theoretical pI: Translated: 7.72; Mature: 7.72

Prosite motif: PS01064 PYRIDOX_OXIDASE

Important sites: BINDING 61-61 BINDING 64-64 BINDING 66-66 BINDING 83-83 BINDING 123-123 BINDING 127-127 BINDING 131-131

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDLSDIRREYTKGGLRRSELPEDPMALFERWMEQAKAAELTDPTAMCVATVDELGQPYQ
CCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHH
RIVLLKRFDEQGFVFFTNLGSRKATQLKHNAHISLLFPWHPLERQVAVTGIAEPLSTAEV
HHHHHHHCCCCCEEEEECCCCCHHHHHHCCCEEEEEECCCCCCHHHHHHHHHCHHHHHHH
LKYFVTRPKDSQIAAWVSAQSSKLSARQVLEAKFMEMKQKFSAGEVPLPSFWGGYLVRPA
HHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCC
SIEFWQGGEHRLHDRFIYEKTAAGWDIERLAP
CEEECCCCCHHHHHHHHHHHHCCCCCHHHCCC
>Mature Secondary Structure 
TDLSDIRREYTKGGLRRSELPEDPMALFERWMEQAKAAELTDPTAMCVATVDELGQPYQ
CCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHH
RIVLLKRFDEQGFVFFTNLGSRKATQLKHNAHISLLFPWHPLERQVAVTGIAEPLSTAEV
HHHHHHHCCCCCEEEEECCCCCHHHHHHCCCEEEEEECCCCCCHHHHHHHHHCHHHHHHH
LKYFVTRPKDSQIAAWVSAQSSKLSARQVLEAKFMEMKQKFSAGEVPLPSFWGGYLVRPA
HHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCC
SIEFWQGGEHRLHDRFIYEKTAAGWDIERLAP
CEEECCCCCHHHHHHHHHHHHCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA