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The map label for this gene is hlyB [H]

Identifier: 119775089

GI number: 119775089

Start: 2382430

End: 2383944

Strand: Direct

Name: hlyB [H]

Synonym: Sama_1954

Alternate gene names: 119775089

Gene position: 2382430-2383944 (Clockwise)

Preceding gene: 119775083

Following gene: 119775090

Centisome position: 55.33

GC content: 53.27

Gene sequence:

>1515_bases
ATGAAAGAAGTGAAGTTTCGCTGGATAGATCAATATCTCATCCACATGACACTCAAAACCAAGTTTGCCATTTTGGCTAT
TGTCCCGGTGCTGATGGTGCTGTCCCTGGCACTGGTGCTGAACATCAAATTTAACGAGACCTTGCTCGAAACCCACCTGA
CACAAAGCCAAAAGCATACCAATGAGGTCAATCAGCTGGTATCGCAGGCGCTCAATTATATTCCCGCTGAGCAGCAAGGC
GCATTTTTGCAAAGTCTCTCCGGTAACACTCAGGTAGTGCCGGTCAATAACTTGGGTAATAAGGCCCAGCAATTGGCCCG
CAGTGGTGGCGGCAGCGACCAGGCTAACGCTAACGCCCGTTATCAAACAGTCAGTGCCATCAGCGACAAGCAGTTGGTCG
CAGTGAATATGCTTGATGCCAAAGCGGTAGCACTGGAATCCGGTAACGATACCTGGTTCGTCATGGGCGCCATCGCGCTG
GTGCTCTTTATCATCTTTATCTTCAGCTACTACATCTCCACCTTTGTTGGTGGCGCCCTGTATACCACGGTAATGGCGCT
TAAACGTGCCGCCGATGGCGACCTCACAGGCAGACTTAACTTCTTCCAGGTCAAAGATGAGTTCAGTATTCTGGCCATCA
GCATCGACTCTTTGGTTGAACGTCAGCATAACCTGGTGAAAAGCATCAACGACGCCACCCGCCAAATCCGTACTGTGGTG
GAGTCCTTCCGCACCAATGCACGGGACGGTCAGGCCCTTGCTGCCAGTCAACGTGCCCATCTCGACTCCCTTGCCACCGC
CATGGAGCAAATGACCGCTGCAGTGCGGGAAGTCGCAAGTAACGCCGAGCATTCATCCCAGGAAACTCAGGAAGCAAACC
AGCAAGTGGCGGCCGGCTCCAAGGATATTGCAACCACAGTGAGCGCCATAGGTCAGCTTTCCAATGAAATCGCCAGGGCA
TCAGATGCTGTAACCGTACTCAATGAAAACGCCAGCCGTATCGATGAGGTGGTAACCACCATTAACGCCATTTCCGAGCA
AACCAATCTGCTGGCGCTTAACGCCGCCATCGAAGCAGCACGCGCCGGTGAACAGGGACGAGGCTTTGCGGTAGTGGCAG
ATGAAGTGCGTACCCTCGCGGGTCGTACGCAGGCAGCCACGGTGGAAATCAAATCCATGATTGAGGCACTGCAATCCGGC
TCCCGTAACCTCACTCAAGTGATGGCGCGGACCGTTGAGCAAGCCGAAGAAGGCAAAAAGCATGTGATAAAGACCGGTGA
GGATCTCGACAGCATCGCCCATCACAGTGCCAAGGTGTTTGAGATGAGCGTGCTGATTGCCACCTCCGCAGAAGAGCAGT
CCGCCGTTGCCAACGAAATTGCCGGCAATCTGATGGAAATCCGTAACCAGTCCCACGATGTGGAACAGTCGGCGAACCAG
TCGGTATCGGGTTGTGATGAACTCCATGCCACCGCCGAAAAACTCGATAAGCTTTTGGTCGGATTAAAACTCTGA

Upstream 100 bases:

>100_bases
AAGTATTCATTCACAAGCATAATTCGGCTGCAATAATAAAGTTCGGTCATCAAGAACCGATAAACATAGGGTCACACGCA
GCCCCGCTCCGAGGTAATTC

Downstream 100 bases:

>100_bases
CCACGCAAAAGGCACCCGGAAGGGTGCCTTTTAGCTTTAAGCTAATGGCAAACAAGAAATTATCCGTTAGACTGGCTGCT
GAGAATGTCATTTTCAGCCC

Product: putative methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 504; Mature: 504

Protein sequence:

>504_residues
MKEVKFRWIDQYLIHMTLKTKFAILAIVPVLMVLSLALVLNIKFNETLLETHLTQSQKHTNEVNQLVSQALNYIPAEQQG
AFLQSLSGNTQVVPVNNLGNKAQQLARSGGGSDQANANARYQTVSAISDKQLVAVNMLDAKAVALESGNDTWFVMGAIAL
VLFIIFIFSYYISTFVGGALYTTVMALKRAADGDLTGRLNFFQVKDEFSILAISIDSLVERQHNLVKSINDATRQIRTVV
ESFRTNARDGQALAASQRAHLDSLATAMEQMTAAVREVASNAEHSSQETQEANQQVAAGSKDIATTVSAIGQLSNEIARA
SDAVTVLNENASRIDEVVTTINAISEQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLAGRTQAATVEIKSMIEALQSG
SRNLTQVMARTVEQAEEGKKHVIKTGEDLDSIAHHSAKVFEMSVLIATSAEEQSAVANEIAGNLMEIRNQSHDVEQSANQ
SVSGCDELHATAEKLDKLLVGLKL

Sequences:

>Translated_504_residues
MKEVKFRWIDQYLIHMTLKTKFAILAIVPVLMVLSLALVLNIKFNETLLETHLTQSQKHTNEVNQLVSQALNYIPAEQQG
AFLQSLSGNTQVVPVNNLGNKAQQLARSGGGSDQANANARYQTVSAISDKQLVAVNMLDAKAVALESGNDTWFVMGAIAL
VLFIIFIFSYYISTFVGGALYTTVMALKRAADGDLTGRLNFFQVKDEFSILAISIDSLVERQHNLVKSINDATRQIRTVV
ESFRTNARDGQALAASQRAHLDSLATAMEQMTAAVREVASNAEHSSQETQEANQQVAAGSKDIATTVSAIGQLSNEIARA
SDAVTVLNENASRIDEVVTTINAISEQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLAGRTQAATVEIKSMIEALQSG
SRNLTQVMARTVEQAEEGKKHVIKTGEDLDSIAHHSAKVFEMSVLIATSAEEQSAVANEIAGNLMEIRNQSHDVEQSANQ
SVSGCDELHATAEKLDKLLVGLKL
>Mature_504_residues
MKEVKFRWIDQYLIHMTLKTKFAILAIVPVLMVLSLALVLNIKFNETLLETHLTQSQKHTNEVNQLVSQALNYIPAEQQG
AFLQSLSGNTQVVPVNNLGNKAQQLARSGGGSDQANANARYQTVSAISDKQLVAVNMLDAKAVALESGNDTWFVMGAIAL
VLFIIFIFSYYISTFVGGALYTTVMALKRAADGDLTGRLNFFQVKDEFSILAISIDSLVERQHNLVKSINDATRQIRTVV
ESFRTNARDGQALAASQRAHLDSLATAMEQMTAAVREVASNAEHSSQETQEANQQVAAGSKDIATTVSAIGQLSNEIARA
SDAVTVLNENASRIDEVVTTINAISEQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLAGRTQAATVEIKSMIEALQSG
SRNLTQVMARTVEQAEEGKKHVIKTGEDLDSIAHHSAKVFEMSVLIATSAEEQSAVANEIAGNLMEIRNQSHDVEQSANQ
SVSGCDELHATAEKLDKLLVGLKL

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=307, Percent_Identity=31.2703583061889, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI2367378, Length=306, Percent_Identity=30.718954248366, Blast_Score=115, Evalue=7e-27,
Organism=Escherichia coli, GI1788195, Length=205, Percent_Identity=36.5853658536585, Blast_Score=108, Evalue=9e-25,
Organism=Escherichia coli, GI1788194, Length=197, Percent_Identity=37.0558375634518, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1789453, Length=243, Percent_Identity=31.6872427983539, Blast_Score=89, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 54435; Mature: 54435

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEVKFRWIDQYLIHMTLKTKFAILAIVPVLMVLSLALVLNIKFNETLLETHLTQSQKHT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
NEVNQLVSQALNYIPAEQQGAFLQSLSGNTQVVPVNNLGNKAQQLARSGGGSDQANANAR
HHHHHHHHHHHHCCCCCCCCHHHHHCCCCCEEEECCCCCHHHHHHHHCCCCCCCCCCCCH
YQTVSAISDKQLVAVNMLDAKAVALESGNDTWFVMGAIALVLFIIFIFSYYISTFVGGAL
HHHHHHCCCCCEEEEEEHHHHHEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
YTTVMALKRAADGDLTGRLNFFQVKDEFSILAISIDSLVERQHNLVKSINDATRQIRTVV
HHHHHHHHHHCCCCCCCCEEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
ESFRTNARDGQALAASQRAHLDSLATAMEQMTAAVREVASNAEHSSQETQEANQQVAAGS
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCC
KDIATTVSAIGQLSNEIARASDAVTVLNENASRIDEVVTTINAISEQTNLLALNAAIEAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCEEEHHHHHHHH
RAGEQGRGFAVVADEVRTLAGRTQAATVEIKSMIEALQSGSRNLTQVMARTVEQAEEGKK
HCCCCCCCEEEEHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHH
HVIKTGEDLDSIAHHSAKVFEMSVLIATSAEEQSAVANEIAGNLMEIRNQSHDVEQSANQ
HHHCCCCHHHHHHHHHHHHHHEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCHHHHHCC
SVSGCDELHATAEKLDKLLVGLKL
CCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKEVKFRWIDQYLIHMTLKTKFAILAIVPVLMVLSLALVLNIKFNETLLETHLTQSQKHT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
NEVNQLVSQALNYIPAEQQGAFLQSLSGNTQVVPVNNLGNKAQQLARSGGGSDQANANAR
HHHHHHHHHHHHCCCCCCCCHHHHHCCCCCEEEECCCCCHHHHHHHHCCCCCCCCCCCCH
YQTVSAISDKQLVAVNMLDAKAVALESGNDTWFVMGAIALVLFIIFIFSYYISTFVGGAL
HHHHHHCCCCCEEEEEEHHHHHEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
YTTVMALKRAADGDLTGRLNFFQVKDEFSILAISIDSLVERQHNLVKSINDATRQIRTVV
HHHHHHHHHHCCCCCCCCEEEEEECCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
ESFRTNARDGQALAASQRAHLDSLATAMEQMTAAVREVASNAEHSSQETQEANQQVAAGS
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCC
KDIATTVSAIGQLSNEIARASDAVTVLNENASRIDEVVTTINAISEQTNLLALNAAIEAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCEEEHHHHHHHH
RAGEQGRGFAVVADEVRTLAGRTQAATVEIKSMIEALQSGSRNLTQVMARTVEQAEEGKK
HCCCCCCCEEEEHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHH
HVIKTGEDLDSIAHHSAKVFEMSVLIATSAEEQSAVANEIAGNLMEIRNQSHDVEQSANQ
HHHCCCCHHHHHHHHHHHHHHEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCHHHHHCC
SVSGCDELHATAEKLDKLLVGLKL
CCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]