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The map label for this gene is dapA [H]

Identifier: 119775043

GI number: 119775043

Start: 2336495

End: 2337376

Strand: Reverse

Name: dapA [H]

Synonym: Sama_1908

Alternate gene names: 119775043

Gene position: 2337376-2336495 (Counterclockwise)

Preceding gene: 119775046

Following gene: 119775042

Centisome position: 54.28

GC content: 54.42

Gene sequence:

>882_bases
ATGATAAACGGAAGCATCGTAGCCTTAATCACGCCTATGAACAGTGATGGCTCAGTGGATTTTGCAAGTCTTGAGAGTTT
AGTCGAGTTTCATATCGCCAATGGCACCGACGCCATTGTGGCCGTGGGGACCACGGGCGAATCGGCTACTCTGCCAATGA
AAGAACACATCAATGTGGTAGCCAAAACCGTTGAGTTTGCCAAGGGCCGTATTCCGGTTATCGGCGGCAACGGCGCTAAT
GCCACTGCCGAGGCAATCGAGCTGACCCAGGCCCTGTCTGCAACTGGTGTTGCGGCCATGCTGGGGGTGACGCCTTATTA
CAACAAGCCCACGCCTAAAGGCCTGGTTGCCCACTATAAAGCGGTGGCTGCAGCTACTGACATTCCGCAAATTCTGTATA
ACGTGCCCGGCCGTACTGCGCTGGACTTGAAGCCTGAGACTGTTGCTGAGCTTTGCGACGTGGCTAACATCATCGGCATC
AAAGAAGCCACGGGTGATGTGAGCCGTGTAGCCCGCCTGCGTGAACTCTGCGGCCCCGACTTTTTGCTGTACAGCGGCGA
TGATGCCACTGCACGTGAGTTTTTGCTGGCTGGCGGTGATGGGGTGATTTCGGTTGCCAACAACATAGTGCCTGCTCAGT
TTAAAAAGATGTGCGCACTGGCGCTGGCCGGTGACATCGAGGGCTCTTTGGCGGCCGATGAACCCATGCGTGGTCTCTAC
AGCACACTCTTTTGCGAAGCCAACCCTATCCCGGTGAAATGGGCTGCCCATCGTATGGGACTCATCAAGGAGGGTTTTAT
TCGTTTGCCACTGACTGAACTTTCTGAGTCCTGCCATGGTCTACTGCTCGATGCCATGAAAAAAGCTGGACTGGAGGTCT
AA

Upstream 100 bases:

>100_bases
ATGCTACCACAAACAAATCCTTTTGAGAGCCCTGTAAATGGCTTGTCAATCGCCATAGGGGTCAGTACCATAGCGAATCC
TGCAACCTTGGGGAAGTCAG

Downstream 100 bases:

>100_bases
GTCTTGAAGTTGAAACAAATTACCCCATTCGTTCTCGTTGCCATGGCAGCTGGTTGCACCACGCCAATGGAGCGCCGTCA
GGCCAACGGGAACGATGAGT

Product: dihydrodipicolinate synthase

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MINGSIVALITPMNSDGSVDFASLESLVEFHIANGTDAIVAVGTTGESATLPMKEHINVVAKTVEFAKGRIPVIGGNGAN
ATAEAIELTQALSATGVAAMLGVTPYYNKPTPKGLVAHYKAVAAATDIPQILYNVPGRTALDLKPETVAELCDVANIIGI
KEATGDVSRVARLRELCGPDFLLYSGDDATAREFLLAGGDGVISVANNIVPAQFKKMCALALAGDIEGSLAADEPMRGLY
STLFCEANPIPVKWAAHRMGLIKEGFIRLPLTELSESCHGLLLDAMKKAGLEV

Sequences:

>Translated_293_residues
MINGSIVALITPMNSDGSVDFASLESLVEFHIANGTDAIVAVGTTGESATLPMKEHINVVAKTVEFAKGRIPVIGGNGAN
ATAEAIELTQALSATGVAAMLGVTPYYNKPTPKGLVAHYKAVAAATDIPQILYNVPGRTALDLKPETVAELCDVANIIGI
KEATGDVSRVARLRELCGPDFLLYSGDDATAREFLLAGGDGVISVANNIVPAQFKKMCALALAGDIEGSLAADEPMRGLY
STLFCEANPIPVKWAAHRMGLIKEGFIRLPLTELSESCHGLLLDAMKKAGLEV
>Mature_293_residues
MINGSIVALITPMNSDGSVDFASLESLVEFHIANGTDAIVAVGTTGESATLPMKEHINVVAKTVEFAKGRIPVIGGNGAN
ATAEAIELTQALSATGVAAMLGVTPYYNKPTPKGLVAHYKAVAAATDIPQILYNVPGRTALDLKPETVAELCDVANIIGI
KEATGDVSRVARLRELCGPDFLLYSGDDATAREFLLAGGDGVISVANNIVPAQFKKMCALALAGDIEGSLAADEPMRGLY
STLFCEANPIPVKWAAHRMGLIKEGFIRLPLTELSESCHGLLLDAMKKAGLEV

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; first step. [C]

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=234, Percent_Identity=29.0598290598291, Blast_Score=89, Evalue=5e-18,
Organism=Escherichia coli, GI1788823, Length=291, Percent_Identity=52.5773195876289, Blast_Score=310, Evalue=8e-86,
Organism=Escherichia coli, GI87082415, Length=283, Percent_Identity=28.6219081272085, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1789620, Length=227, Percent_Identity=30.8370044052863, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1786463, Length=233, Percent_Identity=30.4721030042918, Blast_Score=106, Evalue=2e-24,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625
- InterPro:   IPR020624 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 30632; Mature: 30632

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS00665 DHDPS_1 ; PS00666 DHDPS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINGSIVALITPMNSDGSVDFASLESLVEFHIANGTDAIVAVGTTGESATLPMKEHINVV
CCCCEEEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHH
AKTVEFAKGRIPVIGGNGANATAEAIELTQALSATGVAAMLGVTPYYNKPTPKGLVAHYK
HHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
AVAAATDIPQILYNVPGRTALDLKPETVAELCDVANIIGIKEATGDVSRVARLRELCGPD
HHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHCCCC
FLLYSGDDATAREFLLAGGDGVISVANNIVPAQFKKMCALALAGDIEGSLAADEPMRGLY
EEEECCCCHHHHHHEEECCCCEEEHHCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
STLFCEANPIPVKWAAHRMGLIKEGFIRLPLTELSESCHGLLLDAMKKAGLEV
HHHHCCCCCCCEEHHHHHHHHHHCCCEECCHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MINGSIVALITPMNSDGSVDFASLESLVEFHIANGTDAIVAVGTTGESATLPMKEHINVV
CCCCEEEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHH
AKTVEFAKGRIPVIGGNGANATAEAIELTQALSATGVAAMLGVTPYYNKPTPKGLVAHYK
HHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
AVAAATDIPQILYNVPGRTALDLKPETVAELCDVANIIGIKEATGDVSRVARLRELCGPD
HHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHCCCC
FLLYSGDDATAREFLLAGGDGVISVANNIVPAQFKKMCALALAGDIEGSLAADEPMRGLY
EEEECCCCHHHHHHEEECCCCEEEHHCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
STLFCEANPIPVKWAAHRMGLIKEGFIRLPLTELSESCHGLLLDAMKKAGLEV
HHHHCCCCCCCEEHHHHHHHHHHCCCEECCHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA