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The map label for this gene is cmoB

Identifier: 119774981

GI number: 119774981

Start: 2249020

End: 2250012

Strand: Direct

Name: cmoB

Synonym: Sama_1846

Alternate gene names: 119774981

Gene position: 2249020-2250012 (Clockwise)

Preceding gene: 119774980

Following gene: 119774982

Centisome position: 52.23

GC content: 51.46

Gene sequence:

>993_bases
GTGATCAGTTTCTCAAGCTTTTATCGCCAAATCGCCGATACTCAATTGCAACACTGGCTTGAGTCTTTGCCCGCAATTCT
GGGTGAATGGCAACGCCAACATAAACATGGAAACCTGCCCAAATGGGAGAAGGTGCTGGCAAAGCTGCACTATCCGGCCC
CTGAGTTCCTTGACTTGAAAGACAGCGTGACGATTGGCGATGGGCTGCAACTTGACAGCGGACAAACCGAGAAACTCGAA
AACCTGCTGAAAATACTGCAACCATGGCGCAAGGGGCCGTTCCATGTACATGGGATTCATATTGATACCGAGTGGCGCAG
CGACTGGAAATGGGACAGGGTTTCCCCCCACTTAAGCCCGCTGACCAATCGCACGGTATTGGATGTGGGATGTGGCAGCG
GCTATCACATGTGGCGCATGCTGGGTGCGGGAGCCAAACGGGTGGTGGGAATAGACCCATCTGCACTGTTTCTGTGCCAG
TTTGAAGCCATTAAGCGCCTGATAGATACCGAGCTGCCAGTGCACCTATTGCCACTGGGCATAGAGGAACTGCCGCCGCT
GGATGCGTTCGATACTGTGTTCTCTATGGGCGTGCTTTATCACAGACGCTCCCCCATCGATCACTTGTTACAACTTAGGG
ATCAATTGCGAATGGGTGGTGAACTTGTGTTGGAAACCCTGGTGGTAGATGGTGATAAAGACACGGTTCTGGTGCCCCAA
GATAGATATGGCAAGATGAATAATGTATGGTTTTTACCATCAATTGATGCACTTAAGCTGTGGCTTGAGAAATGTGACTT
TACCGATGTGCGCTGTGTGAATGTGGATGTCACCTCCCTTGCGGAGCAGCGCAGTACCCCATGGATGCAAAATGAATCGC
TTGTGGATTACCTGGATCCCAAGGACGTCAATCTTACAGTAGAGGGATATCCGGCACCCAAGCGGGCCACCTTCATTGCG
GTAAAGAACCGCAGTCCACAGGATGCAGACTGA

Upstream 100 bases:

>100_bases
ACACGCTGGAACAGCACAAAACCCGACTGAACCAAGCCGGCTTCACCCAGGCTGACCTTTGGTTCCAATGTTTTAATTTT
GCATCTATGGTGGCTATCAA

Downstream 100 bases:

>100_bases
GACAAGAACCGCTATCGAAAGGGAAGCAAAGACTATGTTCAAACATACCCTGGCCGTTGCCATCATCGCCGTATGTGCAG
GTTGCAGCACTACCTCCAAA

Product: methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MISFSSFYRQIADTQLQHWLESLPAILGEWQRQHKHGNLPKWEKVLAKLHYPAPEFLDLKDSVTIGDGLQLDSGQTEKLE
NLLKILQPWRKGPFHVHGIHIDTEWRSDWKWDRVSPHLSPLTNRTVLDVGCGSGYHMWRMLGAGAKRVVGIDPSALFLCQ
FEAIKRLIDTELPVHLLPLGIEELPPLDAFDTVFSMGVLYHRRSPIDHLLQLRDQLRMGGELVLETLVVDGDKDTVLVPQ
DRYGKMNNVWFLPSIDALKLWLEKCDFTDVRCVNVDVTSLAEQRSTPWMQNESLVDYLDPKDVNLTVEGYPAPKRATFIA
VKNRSPQDAD

Sequences:

>Translated_330_residues
MISFSSFYRQIADTQLQHWLESLPAILGEWQRQHKHGNLPKWEKVLAKLHYPAPEFLDLKDSVTIGDGLQLDSGQTEKLE
NLLKILQPWRKGPFHVHGIHIDTEWRSDWKWDRVSPHLSPLTNRTVLDVGCGSGYHMWRMLGAGAKRVVGIDPSALFLCQ
FEAIKRLIDTELPVHLLPLGIEELPPLDAFDTVFSMGVLYHRRSPIDHLLQLRDQLRMGGELVLETLVVDGDKDTVLVPQ
DRYGKMNNVWFLPSIDALKLWLEKCDFTDVRCVNVDVTSLAEQRSTPWMQNESLVDYLDPKDVNLTVEGYPAPKRATFIA
VKNRSPQDAD
>Mature_330_residues
MISFSSFYRQIADTQLQHWLESLPAILGEWQRQHKHGNLPKWEKVLAKLHYPAPEFLDLKDSVTIGDGLQLDSGQTEKLE
NLLKILQPWRKGPFHVHGIHIDTEWRSDWKWDRVSPHLSPLTNRTVLDVGCGSGYHMWRMLGAGAKRVVGIDPSALFLCQ
FEAIKRLIDTELPVHLLPLGIEELPPLDAFDTVFSMGVLYHRRSPIDHLLQLRDQLRMGGELVLETLVVDGDKDTVLVPQ
DRYGKMNNVWFLPSIDALKLWLEKCDFTDVRCVNVDVTSLAEQRSTPWMQNESLVDYLDPKDVNLTVEGYPAPKRATFIA
VKNRSPQDAD

Specific function: Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. CmoB family

Homologues:

Organism=Escherichia coli, GI1788178, Length=322, Percent_Identity=61.8012422360248, Blast_Score=415, Evalue=1e-117,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CMOB_SHEAM (A1S6P5)

Other databases:

- EMBL:   CP000507
- RefSeq:   YP_927721.1
- ProteinModelPortal:   A1S6P5
- SMR:   A1S6P5
- STRING:   A1S6P5
- GeneID:   4604096
- GenomeReviews:   CP000507_GR
- KEGG:   saz:Sama_1846
- NMPDR:   fig|326297.7.peg.1737
- eggNOG:   COG0500
- HOGENOM:   HBG296882
- OMA:   DVIFCLG
- PhylomeDB:   A1S6P5
- ProtClustDB:   PRK15068
- HAMAP:   MF_01590
- InterPro:   IPR010017
- TIGRFAMs:   TIGR00452

Pfam domain/function: PF08003 Methyltransf_9

EC number: NA

Molecular weight: Translated: 37775; Mature: 37775

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISFSSFYRQIADTQLQHWLESLPAILGEWQRQHKHGNLPKWEKVLAKLHYPAPEFLDLK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHCCCC
DSVTIGDGLQLDSGQTEKLENLLKILQPWRKGPFHVHGIHIDTEWRSDWKWDRVSPHLSP
CCEEECCCCEECCCCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCCCCCC
LTNRTVLDVGCGSGYHMWRMLGAGAKRVVGIDPSALFLCQFEAIKRLIDTELPVHLLPLG
CCCCEEEEECCCCCHHHHHHHCCCCCEEEECCCCHHEEHHHHHHHHHHCCCCCEEEECCC
IEELPPLDAFDTVFSMGVLYHRRSPIDHLLQLRDQLRMGGELVLETLVVDGDKDTVLVPQ
HHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHEEHHHEECCCCCEEECCC
DRYGKMNNVWFLPSIDALKLWLEKCDFTDVRCVNVDVTSLAEQRSTPWMQNESLVDYLDP
HHCCCCCCEEECCCHHHHHHHHHHCCCCCEEEEECCHHHHHHHHCCCCCCCCCHHHCCCC
KDVNLTVEGYPAPKRATFIAVKNRSPQDAD
CCCEEEEECCCCCCCEEEEEEECCCCCCCC
>Mature Secondary Structure
MISFSSFYRQIADTQLQHWLESLPAILGEWQRQHKHGNLPKWEKVLAKLHYPAPEFLDLK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHCCCC
DSVTIGDGLQLDSGQTEKLENLLKILQPWRKGPFHVHGIHIDTEWRSDWKWDRVSPHLSP
CCEEECCCCEECCCCHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCCCCCC
LTNRTVLDVGCGSGYHMWRMLGAGAKRVVGIDPSALFLCQFEAIKRLIDTELPVHLLPLG
CCCCEEEEECCCCCHHHHHHHCCCCCEEEECCCCHHEEHHHHHHHHHHCCCCCEEEECCC
IEELPPLDAFDTVFSMGVLYHRRSPIDHLLQLRDQLRMGGELVLETLVVDGDKDTVLVPQ
HHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCHHHEEHHHEECCCCCEEECCC
DRYGKMNNVWFLPSIDALKLWLEKCDFTDVRCVNVDVTSLAEQRSTPWMQNESLVDYLDP
HHCCCCCCEEECCCHHHHHHHHHHCCCCCEEEEECCHHHHHHHHCCCCCCCCCHHHCCCC
KDVNLTVEGYPAPKRATFIAVKNRSPQDAD
CCCEEEEECCCCCCCEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA