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The map label for this gene is cmoA

Identifier: 119774980

GI number: 119774980

Start: 2248292

End: 2249023

Strand: Direct

Name: cmoA

Synonym: Sama_1845

Alternate gene names: 119774980

Gene position: 2248292-2249023 (Clockwise)

Preceding gene: 119774972

Following gene: 119774981

Centisome position: 52.21

GC content: 51.37

Gene sequence:

>732_bases
ATGACCAATCAACAGGACACACTGTTCGCCGAGCCAGGCGAGCATCAGGGTAACTTCCAGTTTGACAGTCGCGTTGCCGG
TGTATTTGGCGACATGATCCGCCGCTCAGTGCCCGGTTACACGCAAATCATTAACACGATTGGTGAAATTGCTGACCGCT
GCGTCACGCCAGGCTCCAATGTTTATGATCTGGGCTGTTCTCTGGGAGCCGCGACTCTTGCCATCCGCCGCAAAATCGAA
GGTCGCAATGCGCGCATTTTTGCCATCGATAACAGCGAGCCTATGTTGGTACGGGCTGAAGAAAACCTCTCCGCTTACGT
GAGCGACACCAAAGTTTTCTTTCAGCTGGCTGATATTCGAGATCAAACGTTTGAAAATGCCTCTCTGGTGGTGCTCAACT
TTACCCTGCAGTTTTTGCCGCCAGACGACAGAGACACCCTGCTGGCACGCATCTATCAGGGACTTAACCCCGGCGGTATC
CTGCTGCTGTCTGAAAAACTCAAATTTGACGGCGTCGATGTCCAGGCATTACTGGACTCGCTGCATCTCGATTTCAAACG
GGCAAATGGTTATAGCGAACTGGAAATCAGTCAAAAACGCAGCGCCATTGAGAATGTACTGATCCCCGACACGCTGGAAC
AGCACAAAACCCGACTGAACCAAGCCGGCTTCACCCAGGCTGACCTTTGGTTCCAATGTTTTAATTTTGCATCTATGGTG
GCTATCAAGTGA

Upstream 100 bases:

>100_bases
ATATATTAGACATAAATTTCCACGAAATAGCCAGTGTGCCCTTGCTGGTCAGAAAAGCGTTTCGTTAAAATACAAGGCTA
TATTGTGAGATAAGAATCCC

Downstream 100 bases:

>100_bases
TCAGTTTCTCAAGCTTTTATCGCCAAATCGCCGATACTCAATTGCAACACTGGCTTGAGTCTTTGCCCGCAATTCTGGGT
GAATGGCAACGCCAACATAA

Product: methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 243; Mature: 242

Protein sequence:

>243_residues
MTNQQDTLFAEPGEHQGNFQFDSRVAGVFGDMIRRSVPGYTQIINTIGEIADRCVTPGSNVYDLGCSLGAATLAIRRKIE
GRNARIFAIDNSEPMLVRAEENLSAYVSDTKVFFQLADIRDQTFENASLVVLNFTLQFLPPDDRDTLLARIYQGLNPGGI
LLLSEKLKFDGVDVQALLDSLHLDFKRANGYSELEISQKRSAIENVLIPDTLEQHKTRLNQAGFTQADLWFQCFNFASMV
AIK

Sequences:

>Translated_243_residues
MTNQQDTLFAEPGEHQGNFQFDSRVAGVFGDMIRRSVPGYTQIINTIGEIADRCVTPGSNVYDLGCSLGAATLAIRRKIE
GRNARIFAIDNSEPMLVRAEENLSAYVSDTKVFFQLADIRDQTFENASLVVLNFTLQFLPPDDRDTLLARIYQGLNPGGI
LLLSEKLKFDGVDVQALLDSLHLDFKRANGYSELEISQKRSAIENVLIPDTLEQHKTRLNQAGFTQADLWFQCFNFASMV
AIK
>Mature_242_residues
TNQQDTLFAEPGEHQGNFQFDSRVAGVFGDMIRRSVPGYTQIINTIGEIADRCVTPGSNVYDLGCSLGAATLAIRRKIEG
RNARIFAIDNSEPMLVRAEENLSAYVSDTKVFFQLADIRDQTFENASLVVLNFTLQFLPPDDRDTLLARIYQGLNPGGIL
LLSEKLKFDGVDVQALLDSLHLDFKRANGYSELEISQKRSAIENVLIPDTLEQHKTRLNQAGFTQADLWFQCFNFASMVA
IK

Specific function: Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U)

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. CmoA family

Homologues:

Organism=Escherichia coli, GI1788177, Length=241, Percent_Identity=59.3360995850622, Blast_Score=296, Evalue=8e-82,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CMOA_SHEAM (A1S6P4)

Other databases:

- EMBL:   CP000507
- RefSeq:   YP_927720.1
- ProteinModelPortal:   A1S6P4
- SMR:   A1S6P4
- STRING:   A1S6P4
- GeneID:   4604095
- GenomeReviews:   CP000507_GR
- KEGG:   saz:Sama_1845
- NMPDR:   fig|326297.7.peg.1736
- eggNOG:   COG0500
- HOGENOM:   HBG296860
- OMA:   YSELEVS
- PhylomeDB:   A1S6P4
- ProtClustDB:   CLSK906731
- HAMAP:   MF_01589
- InterPro:   IPR013216
- InterPro:   IPR005271
- PIRSF:   PIRSF006325
- TIGRFAMs:   TIGR00740

Pfam domain/function: PF08241 Methyltransf_11

EC number: NA

Molecular weight: Translated: 27157; Mature: 27026

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: NA

Important sites: BINDING 40-40 BINDING 90-90 BINDING 133-133 BINDING 200-200

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNQQDTLFAEPGEHQGNFQFDSRVAGVFGDMIRRSVPGYTQIINTIGEIADRCVTPGSN
CCCCCCCEEECCCCCCCCEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCC
VYDLGCSLGAATLAIRRKIEGRNARIFAIDNSEPMLVRAEENLSAYVSDTKVFFQLADIR
EEECCCCHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEECCCCEEHHHHHHHHHHHHHHH
DQTFENASLVVLNFTLQFLPPDDRDTLLARIYQGLNPGGILLLSEKLKFDGVDVQALLDS
HCCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHH
LHLDFKRANGYSELEISQKRSAIENVLIPDTLEQHKTRLNQAGFTQADLWFQCFNFASMV
HHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHE
AIK
ECC
>Mature Secondary Structure 
TNQQDTLFAEPGEHQGNFQFDSRVAGVFGDMIRRSVPGYTQIINTIGEIADRCVTPGSN
CCCCCCEEECCCCCCCCEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCC
VYDLGCSLGAATLAIRRKIEGRNARIFAIDNSEPMLVRAEENLSAYVSDTKVFFQLADIR
EEECCCCHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEECCCCEEHHHHHHHHHHHHHHH
DQTFENASLVVLNFTLQFLPPDDRDTLLARIYQGLNPGGILLLSEKLKFDGVDVQALLDS
HCCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHH
LHLDFKRANGYSELEISQKRSAIENVLIPDTLEQHKTRLNQAGFTQADLWFQCFNFASMV
HHHHHHHCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHE
AIK
ECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA