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The map label for this gene is eco [H]

Identifier: 119774889

GI number: 119774889

Start: 2145540

End: 2146097

Strand: Reverse

Name: eco [H]

Synonym: Sama_1754

Alternate gene names: 119774889

Gene position: 2146097-2145540 (Counterclockwise)

Preceding gene: 119774895

Following gene: 119774888

Centisome position: 49.84

GC content: 51.08

Gene sequence:

>558_bases
ATGCAAAAAGCCTTTTCTGTTAAAAATCTGATGTTGACCGGCCTCTTTTCACTGGCAACCCTGTCAGTTGCCCATGCCAC
TTCGCCGGCGCATCCTGACGGGGTAAATCAAAACATGATCACCGCCCAGCACTTTACCTCTGCCGATTATCAGGCGCAGG
AAGCCAGCAAGATGTTTCCGGCCCCCGCTGCCGGTATGGTGCAGCACATCCTGACCCTGCCTGCCCTTGAAAATGAGGGT
AATTACATGGTGGAAGTGCAAATCGGCCAAACCAAGCTGGTGGACTGTAACAAACATGGCCTCAGAGGCGAGCTGCAAAC
CAGAGATCTTCAGGGATGGGGCTACAACTACTATGAAGTCACCGAAATTGGTGAGGGTCCAAGCACCATGATGGCCTGTT
TCGATAAAGCCAAGACAGAAGCCTTTGTGCGCATACCTGGCGACTACAAGTTTGCTTACAACAGCAAGCTGCCGATGGTG
TTTTATATTCCTGAGGGTGCTGAGCTTAAGTACCGCGTATGGCGGGCTGATACTGTGTTCAACACCTCTAAAAACTGA

Upstream 100 bases:

>100_bases
CATGGGCTTTAACCCTTTTTCGAATTAGCCTCGTTTACAGGAATACAGCGGGTATCAAGCCCGATGACTTTTTGGGGATA
TCCCCTATCAAGGAGCTATT

Downstream 100 bases:

>100_bases
TTTTGGCCGGACTTAGCCAATAGCCAGACGAGATACAATTCACGCACGATAAACGAAAAGCCGCACATATGCGGCTTTTT
TATTGGCATAAAGATACCCG

Product: ecotin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MQKAFSVKNLMLTGLFSLATLSVAHATSPAHPDGVNQNMITAQHFTSADYQAQEASKMFPAPAAGMVQHILTLPALENEG
NYMVEVQIGQTKLVDCNKHGLRGELQTRDLQGWGYNYYEVTEIGEGPSTMMACFDKAKTEAFVRIPGDYKFAYNSKLPMV
FYIPEGAELKYRVWRADTVFNTSKN

Sequences:

>Translated_185_residues
MQKAFSVKNLMLTGLFSLATLSVAHATSPAHPDGVNQNMITAQHFTSADYQAQEASKMFPAPAAGMVQHILTLPALENEG
NYMVEVQIGQTKLVDCNKHGLRGELQTRDLQGWGYNYYEVTEIGEGPSTMMACFDKAKTEAFVRIPGDYKFAYNSKLPMV
FYIPEGAELKYRVWRADTVFNTSKN
>Mature_185_residues
MQKAFSVKNLMLTGLFSLATLSVAHATSPAHPDGVNQNMITAQHFTSADYQAQEASKMFPAPAAGMVQHILTLPALENEG
NYMVEVQIGQTKLVDCNKHGLRGELQTRDLQGWGYNYYEVTEIGEGPSTMMACFDKAKTEAFVRIPGDYKFAYNSKLPMV
FYIPEGAELKYRVWRADTVFNTSKN

Specific function: General inhibitor of family S1 serine proteases [H]

COG id: COG4574

COG function: function code R; Serine protease inhibitor ecotin

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protease inhibitor I11 (ecotin) family [H]

Homologues:

Organism=Escherichia coli, GI1788538, Length=139, Percent_Identity=41.0071942446043, Blast_Score=108, Evalue=2e-25,

Paralogues:

None

Copy number: 260 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005658
- InterPro:   IPR023189
- InterPro:   IPR023084 [H]

Pfam domain/function: PF03974 Ecotin [H]

EC number: NA

Molecular weight: Translated: 20613; Mature: 20613

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKAFSVKNLMLTGLFSLATLSVAHATSPAHPDGVNQNMITAQHFTSADYQAQEASKMFP
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHCCC
APAAGMVQHILTLPALENEGNYMVEVQIGQTKLVDCNKHGLRGELQTRDLQGWGYNYYEV
CCHHHHHHHHHHCCCEECCCCEEEEEEECCEEEEECCCCCCCCCCCCCCCCCCCCCEEEE
TEIGEGPSTMMACFDKAKTEAFVRIPGDYKFAYNSKLPMVFYIPEGAELKYRVWRADTVF
EECCCCHHHHHHHHHHCCCEEEEECCCCEEEEECCCCCEEEECCCCCCEEEEEEEECEEE
NTSKN
CCCCC
>Mature Secondary Structure
MQKAFSVKNLMLTGLFSLATLSVAHATSPAHPDGVNQNMITAQHFTSADYQAQEASKMFP
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHCCC
APAAGMVQHILTLPALENEGNYMVEVQIGQTKLVDCNKHGLRGELQTRDLQGWGYNYYEV
CCHHHHHHHHHHCCCEECCCCEEEEEEECCEEEEECCCCCCCCCCCCCCCCCCCCCEEEE
TEIGEGPSTMMACFDKAKTEAFVRIPGDYKFAYNSKLPMVFYIPEGAELKYRVWRADTVF
EECCCCHHHHHHHHHHCCCEEEEECCCCEEEEECCCCCEEEECCCCCCEEEEEEEECEEE
NTSKN
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]