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The map label for this gene is yfbQ [H]

Identifier: 119774833

GI number: 119774833

Start: 2076712

End: 2077926

Strand: Reverse

Name: yfbQ [H]

Synonym: Sama_1697

Alternate gene names: 119774833

Gene position: 2077926-2076712 (Counterclockwise)

Preceding gene: 119774835

Following gene: 119774832

Centisome position: 48.25

GC content: 51.11

Gene sequence:

>1215_bases
ATGCGTCCTATCATTAAGTCCAATAAATTAGACACCGTTTGCTACGATATTCGTGGTCCGGTGCACAAGGAAGCCCGTCG
TCTGGAAGACGAAGGCCACAGGATCCTCAAACTGAATATTGGCAACCCGGCCCCCTTTGGTTTCGAAGCACCGGAAGAAA
TCGTCCGTGATGTCATTTTGAATCTCCCCAGCGCCCAGGGCTATTGTGAGTCCAAGGGGCTGTTTTCTGCCCGAAAAGCC
ATAGTGCAGCATTATCAGTCCCAGGGTATTTTTGGCGTTGATATTGAAGATGTGTATATAGGTAACGGTGTCTCTGAATT
GATTGTGATGGCATTGCAGGGGCTTCTAAACGGTGATGATGAAGTGCTTATCCCGTCCCCCGATTACCCACTTTGGACCG
CTGCGGCCAACCTCGCCGGCGGCAAAGCGGTACACTATCGCTGTGATGAAGAATCCGATTGGTTTCCCTGTCTCGATGAT
ATCAAAGCCAAAATCAGCCCACGCACTCGGGCGATTGTGATAATCAATCCCAACAATCCAACCGGTGCGGTATACAGCCG
TGAACTTTTACTCGAGATTATTGAGCTTTGTCGCCAGCATTCCCTAATCCTCTTTGCCGATGAGATTTACGATAAAATCC
TCTACGACGACGCTGTGCACATCCCGGCTGCCGGTCTGTCCGATGACATTCTTACTGTGACCTTTAATGGCCTGTCCAAG
GCCTATCGCGCAGCCGGATTCCGTGTCGGTTGGATGATGCTCTCAGGCAACCTTAAAGCCGCCAAAAGCTATATCGAAGG
TCTGGATATGCTGGCCTCCATGCGGCTGTGTGCAAACGTGCCCAACCAACATGCGGTGCAAACTGCGCTCGGTGGCTACC
AGAGTATTAACGAGCTAATTTTGCCTAAAGGCCGGTTAAGTGTGCAGCGCGACACCTGCTACGAGTACCTCAATGCGATC
CCCGGGGTCAGCTGTAAAAAGCCCAAGGGTGCGCTGTATGCCTTCCCCAAATTGGATCCCAAGCGATTTAACCTGCGTGA
CGACGAGCGATTGGTGCTGGATTTGTTAAAGGAAAAGAAAATTCTGCTGGTCCAGGGCAGTGCCTTTAACTGGCCGGAGC
CGGATCATTTGCGGGTGGTATTTTTACCCCACAAGGAAGATCTGGAAAAGGCGCTGGGCGCCTTTGGTGAGTTTTTGGAA
AACTATCGCCAGTAA

Upstream 100 bases:

>100_bases
TTTGAGGTTTATTCTCTTTTATGTTGTCTTGAACTTGGTTATTGTGAGCCTCTGCAAGCACGCCATATTTTTCCAACATA
ATAGGGTCCAGAGGTACAGG

Downstream 100 bases:

>100_bases
CCCAGCCGCATCCTATTACGCCTGAGACAGAAAACAGACGCCGACAGCCATGTCGGCGTCTGTGTTTATGCAGTTCGCTT
GTTCATGTGACATTCTTCAT

Product: aminotransferase AlaT

Products: oxaloacetate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MRPIIKSNKLDTVCYDIRGPVHKEARRLEDEGHRILKLNIGNPAPFGFEAPEEIVRDVILNLPSAQGYCESKGLFSARKA
IVQHYQSQGIFGVDIEDVYIGNGVSELIVMALQGLLNGDDEVLIPSPDYPLWTAAANLAGGKAVHYRCDEESDWFPCLDD
IKAKISPRTRAIVIINPNNPTGAVYSRELLLEIIELCRQHSLILFADEIYDKILYDDAVHIPAAGLSDDILTVTFNGLSK
AYRAAGFRVGWMMLSGNLKAAKSYIEGLDMLASMRLCANVPNQHAVQTALGGYQSINELILPKGRLSVQRDTCYEYLNAI
PGVSCKKPKGALYAFPKLDPKRFNLRDDERLVLDLLKEKKILLVQGSAFNWPEPDHLRVVFLPHKEDLEKALGAFGEFLE
NYRQ

Sequences:

>Translated_404_residues
MRPIIKSNKLDTVCYDIRGPVHKEARRLEDEGHRILKLNIGNPAPFGFEAPEEIVRDVILNLPSAQGYCESKGLFSARKA
IVQHYQSQGIFGVDIEDVYIGNGVSELIVMALQGLLNGDDEVLIPSPDYPLWTAAANLAGGKAVHYRCDEESDWFPCLDD
IKAKISPRTRAIVIINPNNPTGAVYSRELLLEIIELCRQHSLILFADEIYDKILYDDAVHIPAAGLSDDILTVTFNGLSK
AYRAAGFRVGWMMLSGNLKAAKSYIEGLDMLASMRLCANVPNQHAVQTALGGYQSINELILPKGRLSVQRDTCYEYLNAI
PGVSCKKPKGALYAFPKLDPKRFNLRDDERLVLDLLKEKKILLVQGSAFNWPEPDHLRVVFLPHKEDLEKALGAFGEFLE
NYRQ
>Mature_404_residues
MRPIIKSNKLDTVCYDIRGPVHKEARRLEDEGHRILKLNIGNPAPFGFEAPEEIVRDVILNLPSAQGYCESKGLFSARKA
IVQHYQSQGIFGVDIEDVYIGNGVSELIVMALQGLLNGDDEVLIPSPDYPLWTAAANLAGGKAVHYRCDEESDWFPCLDD
IKAKISPRTRAIVIINPNNPTGAVYSRELLLEIIELCRQHSLILFADEIYDKILYDDAVHIPAAGLSDDILTVTFNGLSK
AYRAAGFRVGWMMLSGNLKAAKSYIEGLDMLASMRLCANVPNQHAVQTALGGYQSINELILPKGRLSVQRDTCYEYLNAI
PGVSCKKPKGALYAFPKLDPKRFNLRDDERLVLDLLKEKKILLVQGSAFNWPEPDHLRVVFLPHKEDLEKALGAFGEFLE
NYRQ

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4507369, Length=376, Percent_Identity=26.8617021276596, Blast_Score=132, Evalue=6e-31,
Organism=Homo sapiens, GI4885351, Length=450, Percent_Identity=27.1111111111111, Blast_Score=128, Evalue=7e-30,
Organism=Homo sapiens, GI19263340, Length=468, Percent_Identity=26.9230769230769, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI215599424, Length=377, Percent_Identity=28.1167108753316, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI95147551, Length=170, Percent_Identity=30.5882352941176, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI169881279, Length=170, Percent_Identity=30.5882352941176, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI56713254, Length=303, Percent_Identity=25.0825082508251, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI56713256, Length=303, Percent_Identity=25.0825082508251, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI169881281, Length=167, Percent_Identity=29.940119760479, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI149944424, Length=379, Percent_Identity=22.6912928759894, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1788627, Length=404, Percent_Identity=70.2970297029703, Blast_Score=610, Evalue=1e-176,
Organism=Escherichia coli, GI1788722, Length=399, Percent_Identity=24.5614035087719, Blast_Score=109, Evalue=4e-25,
Organism=Escherichia coli, GI1786816, Length=281, Percent_Identity=22.7758007117438, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1787909, Length=297, Percent_Identity=21.5488215488215, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17567663, Length=377, Percent_Identity=28.1167108753316, Blast_Score=154, Evalue=9e-38,
Organism=Caenorhabditis elegans, GI71981209, Length=466, Percent_Identity=25.9656652360515, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI71981215, Length=295, Percent_Identity=27.1186440677966, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI71994476, Length=204, Percent_Identity=27.4509803921569, Blast_Score=81, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI71994472, Length=204, Percent_Identity=27.4509803921569, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17567369, Length=174, Percent_Identity=29.3103448275862, Blast_Score=80, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6323118, Length=378, Percent_Identity=28.5714285714286, Blast_Score=130, Evalue=3e-31,
Organism=Saccharomyces cerevisiae, GI6320317, Length=472, Percent_Identity=26.271186440678, Blast_Score=126, Evalue=6e-30,
Organism=Saccharomyces cerevisiae, GI6322401, Length=237, Percent_Identity=26.5822784810127, Blast_Score=106, Evalue=6e-24,
Organism=Drosophila melanogaster, GI18859735, Length=378, Percent_Identity=25.3968253968254, Blast_Score=144, Evalue=8e-35,
Organism=Drosophila melanogaster, GI45551451, Length=472, Percent_Identity=25.635593220339, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24641770, Length=472, Percent_Identity=25.635593220339, Blast_Score=112, Evalue=5e-25,
Organism=Drosophila melanogaster, GI24641760, Length=472, Percent_Identity=25.635593220339, Blast_Score=112, Evalue=5e-25,
Organism=Drosophila melanogaster, GI24641768, Length=472, Percent_Identity=25.635593220339, Blast_Score=112, Evalue=5e-25,
Organism=Drosophila melanogaster, GI24641766, Length=472, Percent_Identity=25.635593220339, Blast_Score=112, Evalue=5e-25,
Organism=Drosophila melanogaster, GI24641764, Length=472, Percent_Identity=25.635593220339, Blast_Score=112, Evalue=5e-25,
Organism=Drosophila melanogaster, GI28573069, Length=331, Percent_Identity=25.6797583081571, Blast_Score=85, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24646114, Length=331, Percent_Identity=25.6797583081571, Blast_Score=85, Evalue=8e-17,
Organism=Drosophila melanogaster, GI28573067, Length=331, Percent_Identity=25.6797583081571, Blast_Score=85, Evalue=8e-17,
Organism=Drosophila melanogaster, GI28573065, Length=331, Percent_Identity=25.6797583081571, Blast_Score=85, Evalue=8e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.1

Molecular weight: Translated: 45137; Mature: 45137

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPIIKSNKLDTVCYDIRGPVHKEARRLEDEGHRILKLNIGNPAPFGFEAPEEIVRDVIL
CCCCCCCCCCCEEEEECCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHH
NLPSAQGYCESKGLFSARKAIVQHYQSQGIFGVDIEDVYIGNGVSELIVMALQGLLNGDD
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEECCCCCEEECCCHHHHHHHHHHHHCCCCC
EVLIPSPDYPLWTAAANLAGGKAVHYRCDEESDWFPCLDDIKAKISPRTRAIVIINPNNP
CEEECCCCCCHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHCCCCEEEEEEEECCCC
TGAVYSRELLLEIIELCRQHSLILFADEIYDKILYDDAVHIPAAGLSDDILTVTFNGLSK
CCHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEHHHHH
AYRAAGFRVGWMMLSGNLKAAKSYIEGLDMLASMRLCANVPNQHAVQTALGGYQSINELI
HHHHCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHH
LPKGRLSVQRDTCYEYLNAIPGVSCKKPKGALYAFPKLDPKRFNLRDDERLVLDLLKEKK
CCCCCCEECHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHCCCC
ILLVQGSAFNWPEPDHLRVVFLPHKEDLEKALGAFGEFLENYRQ
EEEEECCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRPIIKSNKLDTVCYDIRGPVHKEARRLEDEGHRILKLNIGNPAPFGFEAPEEIVRDVIL
CCCCCCCCCCCEEEEECCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHH
NLPSAQGYCESKGLFSARKAIVQHYQSQGIFGVDIEDVYIGNGVSELIVMALQGLLNGDD
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCEEECCCCCEEECCCHHHHHHHHHHHHCCCCC
EVLIPSPDYPLWTAAANLAGGKAVHYRCDEESDWFPCLDDIKAKISPRTRAIVIINPNNP
CEEECCCCCCHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHCCCCEEEEEEEECCCC
TGAVYSRELLLEIIELCRQHSLILFADEIYDKILYDDAVHIPAAGLSDDILTVTFNGLSK
CCHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEHHHHH
AYRAAGFRVGWMMLSGNLKAAKSYIEGLDMLASMRLCANVPNQHAVQTALGGYQSINELI
HHHHCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHH
LPKGRLSVQRDTCYEYLNAIPGVSCKKPKGALYAFPKLDPKRFNLRDDERLVLDLLKEKK
CCCCCCEECHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHCCCC
ILLVQGSAFNWPEPDHLRVVFLPHKEDLEKALGAFGEFLENYRQ
EEEEECCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate; 2-oxoglutarate

Specific reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]