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The map label for this gene is hypB [H]

Identifier: 119774809

GI number: 119774809

Start: 2045274

End: 2046050

Strand: Reverse

Name: hypB [H]

Synonym: Sama_1673

Alternate gene names: 119774809

Gene position: 2046050-2045274 (Counterclockwise)

Preceding gene: 119774810

Following gene: 119774808

Centisome position: 47.51

GC content: 53.15

Gene sequence:

>777_bases
ATGTGCCAGGACTGTGGCTGCTCATTACCGCGATTCGGGATGCAAGATACCCATCAGCACGCTCATGAACATCATGAGCT
CACCACCAATCCCCAACTGAACGACGCCAAAACGCTGTCAGTTATCCATAAGATTCTGGATAAGAATGACGTGGAAGCGG
CTCACAACCGCGGTCATTTCGAAGCCCATCAGATAAGCGCCTATAACCTGATGAGCAGTCCCGGCAGCGGTAAAACCACC
TTGCTGGAGTGCTTGCATGAATATCTGGGACTGACCTACGGCGTGATTGAGGGCGATCTTGAGACCTCAAAAGATGCCGA
TCGCCTGCTGGCGAAAGGTATCCAGGCGGTGCAAATTCAAACCGGCAGCGCCTGCCATTTGGACGCCTTTATGGTCCATG
GTGCCCTGCACCGTCTTACTCTGGATGAAGGCTCCATCGCCTTTATCGAAAACGTGGGCAATCTGGTGTGCCCGGCTAGC
TATGATGTGGGTACCCATCGCAATATCGTGCTCTTATCCGTGCCTGAGGGTGACGACAAAATTGCAAAATACCCGGTGAT
GTTCCGCCGCGCGGATCTGGTTCTTATTACCAAGTCCGATCTCACGCCCTACTTTGACTTCAGTATTGAGAGCGCCAAAG
AGAGCCTCAGAGCGCTCAATCCCCAGTGTGAAGTGATTGAATTGTCTGTCAAGGATGGTCGCGGCATGGACAGGCTCGCA
ACCTGGTTAAAGCAGGACCACAGCAGCCGCTATCATGCCGACGTTGGGGGAAATTGA

Upstream 100 bases:

>100_bases
CGCCAGATTGTCCCGTCATTCCGAAATGCTGACCCACATCAAACCTTTCGTTAATCAGCTGTATCAGAATTGTGCCAAAT
AGCTCAAGGAGACTCCCTAC

Downstream 100 bases:

>100_bases
GTTATGTGCCTTTCTGTCCCTTCTGAAGTGGTGGCACTGCATGACGATGAGCAGGCCATTACCGTCGATACCCTGGGGGT
ACGGCGAAAAGTCAGTCGTC

Product: hydrogenase accessory protein HypB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MCQDCGCSLPRFGMQDTHQHAHEHHELTTNPQLNDAKTLSVIHKILDKNDVEAAHNRGHFEAHQISAYNLMSSPGSGKTT
LLECLHEYLGLTYGVIEGDLETSKDADRLLAKGIQAVQIQTGSACHLDAFMVHGALHRLTLDEGSIAFIENVGNLVCPAS
YDVGTHRNIVLLSVPEGDDKIAKYPVMFRRADLVLITKSDLTPYFDFSIESAKESLRALNPQCEVIELSVKDGRGMDRLA
TWLKQDHSSRYHADVGGN

Sequences:

>Translated_258_residues
MCQDCGCSLPRFGMQDTHQHAHEHHELTTNPQLNDAKTLSVIHKILDKNDVEAAHNRGHFEAHQISAYNLMSSPGSGKTT
LLECLHEYLGLTYGVIEGDLETSKDADRLLAKGIQAVQIQTGSACHLDAFMVHGALHRLTLDEGSIAFIENVGNLVCPAS
YDVGTHRNIVLLSVPEGDDKIAKYPVMFRRADLVLITKSDLTPYFDFSIESAKESLRALNPQCEVIELSVKDGRGMDRLA
TWLKQDHSSRYHADVGGN
>Mature_258_residues
MCQDCGCSLPRFGMQDTHQHAHEHHELTTNPQLNDAKTLSVIHKILDKNDVEAAHNRGHFEAHQISAYNLMSSPGSGKTT
LLECLHEYLGLTYGVIEGDLETSKDADRLLAKGIQAVQIQTGSACHLDAFMVHGALHRLTLDEGSIAFIENVGNLVCPAS
YDVGTHRNIVLLSVPEGDDKIAKYPVMFRRADLVLITKSDLTPYFDFSIESAKESLRALNPQCEVIELSVKDGRGMDRLA
TWLKQDHSSRYHADVGGN

Specific function: Plays a role in both the hydrogenase and the urease nickel cofactor insertion step [H]

COG id: COG0378

COG function: function code OK; Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypB/hupM family [H]

Homologues:

Organism=Escherichia coli, GI1789082, Length=244, Percent_Identity=45.0819672131148, Blast_Score=196, Evalue=2e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR004392
- InterPro:   IPR012202 [H]

Pfam domain/function: PF02492 cobW [H]

EC number: NA

Molecular weight: Translated: 28502; Mature: 28502

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: PS00028 ZINC_FINGER_C2H2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCQDCGCSLPRFGMQDTHQHAHEHHELTTNPQLNDAKTLSVIHKILDKNDVEAAHNRGHF
CCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHCCCCC
EAHQISAYNLMSSPGSGKTTLLECLHEYLGLTYGVIEGDLETSKDADRLLAKGIQAVQIQ
CHHHEEEEHHCCCCCCCHHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHCCCEEEEEE
TGSACHLDAFMVHGALHRLTLDEGSIAFIENVGNLVCPASYDVGTHRNIVLLSVPEGDDK
CCCCHHHHHHHHHHHHHEEEECCCCEEEEECCCCEECCCCCCCCCCCCEEEEECCCCCCC
IAKYPVMFRRADLVLITKSDLTPYFDFSIESAKESLRALNPQCEVIELSVKDGRGMDRLA
HHHCCCEEEECCEEEEECCCCCEEECCCHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHH
TWLKQDHSSRYHADVGGN
HHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MCQDCGCSLPRFGMQDTHQHAHEHHELTTNPQLNDAKTLSVIHKILDKNDVEAAHNRGHF
CCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHCCCCC
EAHQISAYNLMSSPGSGKTTLLECLHEYLGLTYGVIEGDLETSKDADRLLAKGIQAVQIQ
CHHHEEEEHHCCCCCCCHHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHCCCEEEEEE
TGSACHLDAFMVHGALHRLTLDEGSIAFIENVGNLVCPASYDVGTHRNIVLLSVPEGDDK
CCCCHHHHHHHHHHHHHEEEECCCCEEEEECCCCEECCCCCCCCCCCCEEEEECCCCCCC
IAKYPVMFRRADLVLITKSDLTPYFDFSIESAKESLRALNPQCEVIELSVKDGRGMDRLA
HHHCCCEEEECCEEEEECCCCCEEECCCHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHH
TWLKQDHSSRYHADVGGN
HHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682; 11123699 [H]