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The map label for this gene is hypE [H]

Identifier: 119774806

GI number: 119774806

Start: 2042878

End: 2043882

Strand: Reverse

Name: hypE [H]

Synonym: Sama_1670

Alternate gene names: 119774806

Gene position: 2043882-2042878 (Counterclockwise)

Preceding gene: 119774807

Following gene: 119774805

Centisome position: 47.46

GC content: 57.51

Gene sequence:

>1005_bases
ATGTCGACTAACAGTATTCAGCTTGCCCACGGTGGCGGCGGCCTGGAAATGAATAAACTCATTCGTAACCTGTTTTTCAA
GGCCTTTGATAATTGCATCCTGAGAAATGAAGAAGATGCCGCGCTGCTGAACCTGCAGGGCCCCACCGCCTTTACCACAG
ACTCTTTCACCGTATCACCGCTGTTTTTTGCCGGGGGCGACATAGGCAAGCTGGCCATTGCCGGTACGGTCAATGATTTG
GCCATGATGGGCGCCGAGCCCCAGTATTTAAGCCTTGGGGTAATCATTGAAGAAGGCTTCCCCATGGCATCACTCGAAAC
CATAGTGGCCTCCATGGCCAGCGAGCTGAAAAAGTGCGGTGCTAAAATCGTCTGCGGCGATACCAAGGTGGTTCCCAAAG
GCTGTGCCGATGGTCTCTTTTTAAACACCACAGGGGTGGGCCGTATTGTGAAACCGGGCTTGTCAGCCAAACGCCTGATG
CCCGGTGATGCGATTCTGGTGTCCGGCGACATAGGACGCCACGGGGCGGCCATCCTGATGGCGCGGGAAGGACTGGAGCT
GGAGTCCGGCCTTGTGAGCGACTGTGCCACCCTCTGGGGCGCAGTTGAGCAGCTCTTGGTGCATCCGTTCGATATCCATG
CCATGCGCGACGCTACCCGGGGCGGACTTTCCGCCGTACTGAATGAGTGGGCCGCTGCCTCTGATGTGATGATTGAAGTC
GACGAGGCTGCCGTTCCTGTGAGCGATGAAGTAAAAGGCCTGTGTGAACTCTACGGCTTTGAGGCCACAGATCTCGCCAA
TGAAGGCACCTTCGTCATGGCGCTGCCTGCCGCGCAGGCTGACGGTGCACTGGAGGTCCTCAAGCGCTTTGGCCATTGCG
AGAATGCGGTCATCATAGGCCGCGTCGGTGAAAGCCCGGCCGGGCGAGTGATACTGCACACCCCATGGGGCAGTAACAGG
TACCTCGACCTGCCCGCCGGTGAATTACTGCCAAGGATTTGCTGA

Upstream 100 bases:

>100_bases
GTCTTTGGCCGTGGCTGCACGCCCCAAACGCCCCTTGGCAGTTGCATGGTCAGCTCAGAAGGCGCCTGCAATGCCTATTA
CCGCTACCATGGAGTCCAGC

Downstream 100 bases:

>100_bases
TGCATGAATTTTCCATCGTCCAGGCGCTGCTCGACAGCTGCGAGCAACATGCCCGCAGCGTCGGGGCAACTGGGATAAGT
CGGGTCAGTATTCGCATTGG

Product: hydrogenase expression/formation protein HypE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MSTNSIQLAHGGGGLEMNKLIRNLFFKAFDNCILRNEEDAALLNLQGPTAFTTDSFTVSPLFFAGGDIGKLAIAGTVNDL
AMMGAEPQYLSLGVIIEEGFPMASLETIVASMASELKKCGAKIVCGDTKVVPKGCADGLFLNTTGVGRIVKPGLSAKRLM
PGDAILVSGDIGRHGAAILMAREGLELESGLVSDCATLWGAVEQLLVHPFDIHAMRDATRGGLSAVLNEWAAASDVMIEV
DEAAVPVSDEVKGLCELYGFEATDLANEGTFVMALPAAQADGALEVLKRFGHCENAVIIGRVGESPAGRVILHTPWGSNR
YLDLPAGELLPRIC

Sequences:

>Translated_334_residues
MSTNSIQLAHGGGGLEMNKLIRNLFFKAFDNCILRNEEDAALLNLQGPTAFTTDSFTVSPLFFAGGDIGKLAIAGTVNDL
AMMGAEPQYLSLGVIIEEGFPMASLETIVASMASELKKCGAKIVCGDTKVVPKGCADGLFLNTTGVGRIVKPGLSAKRLM
PGDAILVSGDIGRHGAAILMAREGLELESGLVSDCATLWGAVEQLLVHPFDIHAMRDATRGGLSAVLNEWAAASDVMIEV
DEAAVPVSDEVKGLCELYGFEATDLANEGTFVMALPAAQADGALEVLKRFGHCENAVIIGRVGESPAGRVILHTPWGSNR
YLDLPAGELLPRIC
>Mature_333_residues
STNSIQLAHGGGGLEMNKLIRNLFFKAFDNCILRNEEDAALLNLQGPTAFTTDSFTVSPLFFAGGDIGKLAIAGTVNDLA
MMGAEPQYLSLGVIIEEGFPMASLETIVASMASELKKCGAKIVCGDTKVVPKGCADGLFLNTTGVGRIVKPGLSAKRLMP
GDAILVSGDIGRHGAAILMAREGLELESGLVSDCATLWGAVEQLLVHPFDIHAMRDATRGGLSAVLNEWAAASDVMIEVD
EAAVPVSDEVKGLCELYGFEATDLANEGTFVMALPAAQADGALEVLKRFGHCENAVIIGRVGESPAGRVILHTPWGSNRY
LDLPAGELLPRIC

Specific function: Unknown

COG id: COG0309

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypE family [H]

Homologues:

Organism=Escherichia coli, GI226510967, Length=338, Percent_Identity=48.5207100591716, Blast_Score=278, Evalue=4e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR011854
- InterPro:   IPR016188 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: NA

Molecular weight: Translated: 35114; Mature: 34983

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTNSIQLAHGGGGLEMNKLIRNLFFKAFDNCILRNEEDAALLNLQGPTAFTTDSFTVSP
CCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEECCCEEECE
LFFAGGDIGKLAIAGTVNDLAMMGAEPQYLSLGVIIEEGFPMASLETIVASMASELKKCG
EEECCCCCCEEEEECCHHHHHHHCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHCC
AKIVCGDTKVVPKGCADGLFLNTTGVGRIVKPGLSAKRLMPGDAILVSGDIGRHGAAILM
CEEEECCCEECCCCCCCCEEEECCCCCCEECCCCCCCCCCCCCEEEEECCCCCCCEEEEE
AREGLELESGLVSDCATLWGAVEQLLVHPFDIHAMRDATRGGLSAVLNEWAAASDVMIEV
EECCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEE
DEAAVPVSDEVKGLCELYGFEATDLANEGTFVMALPAAQADGALEVLKRFGHCENAVIIG
CCCCCCCCHHHHHHHHHHCCCHHHCCCCCEEEEEECCCCCCCHHHHHHHHCCCCCEEEEE
RVGESPAGRVILHTPWGSNRYLDLPAGELLPRIC
ECCCCCCCCEEEECCCCCCEEEECCHHHHHCCCC
>Mature Secondary Structure 
STNSIQLAHGGGGLEMNKLIRNLFFKAFDNCILRNEEDAALLNLQGPTAFTTDSFTVSP
CCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEECCCEEECE
LFFAGGDIGKLAIAGTVNDLAMMGAEPQYLSLGVIIEEGFPMASLETIVASMASELKKCG
EEECCCCCCEEEEECCHHHHHHHCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHHHHHCC
AKIVCGDTKVVPKGCADGLFLNTTGVGRIVKPGLSAKRLMPGDAILVSGDIGRHGAAILM
CEEEECCCEECCCCCCCCEEEECCCCCCEECCCCCCCCCCCCCEEEEECCCCCCCEEEEE
AREGLELESGLVSDCATLWGAVEQLLVHPFDIHAMRDATRGGLSAVLNEWAAASDVMIEV
EECCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEE
DEAAVPVSDEVKGLCELYGFEATDLANEGTFVMALPAAQADGALEVLKRFGHCENAVIIG
CCCCCCCCHHHHHHHHHHCCCHHHCCCCCEEEEEECCCCCCCHHHHHHHHCCCCCEEEEE
RVGESPAGRVILHTPWGSNRYLDLPAGELLPRIC
ECCCCCCCCEEEECCCCCCEEEECCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1849603; 9278503 [H]