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The map label for this gene is can [H]

Identifier: 119774778

GI number: 119774778

Start: 2008318

End: 2008929

Strand: Reverse

Name: can [H]

Synonym: Sama_1642

Alternate gene names: 119774778

Gene position: 2008929-2008318 (Counterclockwise)

Preceding gene: 119774779

Following gene: 119774777

Centisome position: 46.65

GC content: 55.07

Gene sequence:

>612_bases
ATGAAACTACTCAAACCCTTGTTCGACAATAACCGTCGATGGGCACAGCGCATCCTGCAGGAAAACCCGGGCTTTTTCGA
AACCCTGGCCAAGCAGCAAAACCCCGAATACCTGTGGATTGGTTGCTCCGATAGCCGAGTTCCCTCCAATCAAATCATTG
ACTTGCTGCCCGGAGAGGTCTTTGTTCACCGTAATATCGCCAACATGGTGATCCACACCGACCTCAACTGTCTGTCGGTG
CTTCAGTACGCAGTGGACGTGCTGCAGGTGAAACACATCATGGTGGTGGGCCATTACGGCTGCGGCGGCGTCCGTGCCGC
CATGGGCAGCGCTCGCCTTGGCCTTATCGACAACTGGCTGGGTCATCTTCGTGATATACATCGCCTGCACAACGATGAGC
TGACAAACCTTGACGATCAGGCACGCTTTGACCGCCTGTGCGAGCTCAATGTGATTGAGCAGGTGGCCAATGTCAGCGAA
TCAAACATAGTCCAGGAAGCCTGGGCCCGCGGTCAGGAAGTCGCCATCCACGGTTGGATATATGGCATCACCAACGGACT
GCTCACCGACCTGGATGTTACCGTCGACCGGGAGACCTTTCTTGGCCAATAA

Upstream 100 bases:

>100_bases
GTATTTTCGTTTGGATCACAGCTTTTTAAGATGGATTGACCAGCCACGGGAAAATTTCCTGATACACTAGCGCCGAATTT
CGCCAAATTACGACGACAAG

Downstream 100 bases:

>100_bases
GGCTGAGTAAATCCACAGGCAGCCAGCGCGCTGCCTTTTTTGTTTTTTTTCGCCCTCCCCATCGCTATCACCTTGCCAAC
ACAGGTATAATCTTCAGGTT

Product: carbonate dehydratase

Products: NA

Alternate protein names: Carbonate dehydratase 2 [H]

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MKLLKPLFDNNRRWAQRILQENPGFFETLAKQQNPEYLWIGCSDSRVPSNQIIDLLPGEVFVHRNIANMVIHTDLNCLSV
LQYAVDVLQVKHIMVVGHYGCGGVRAAMGSARLGLIDNWLGHLRDIHRLHNDELTNLDDQARFDRLCELNVIEQVANVSE
SNIVQEAWARGQEVAIHGWIYGITNGLLTDLDVTVDRETFLGQ

Sequences:

>Translated_203_residues
MKLLKPLFDNNRRWAQRILQENPGFFETLAKQQNPEYLWIGCSDSRVPSNQIIDLLPGEVFVHRNIANMVIHTDLNCLSV
LQYAVDVLQVKHIMVVGHYGCGGVRAAMGSARLGLIDNWLGHLRDIHRLHNDELTNLDDQARFDRLCELNVIEQVANVSE
SNIVQEAWARGQEVAIHGWIYGITNGLLTDLDVTVDRETFLGQ
>Mature_203_residues
MKLLKPLFDNNRRWAQRILQENPGFFETLAKQQNPEYLWIGCSDSRVPSNQIIDLLPGEVFVHRNIANMVIHTDLNCLSV
LQYAVDVLQVKHIMVVGHYGCGGVRAAMGSARLGLIDNWLGHLRDIHRLHNDELTNLDDQARFDRLCELNVIEQVANVSE
SNIVQEAWARGQEVAIHGWIYGITNGLLTDLDVTVDRETFLGQ

Specific function: Unknown

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI1786318, Length=201, Percent_Identity=60.1990049751244, Blast_Score=258, Evalue=2e-70,
Organism=Escherichia coli, GI1786534, Length=196, Percent_Identity=30.1020408163265, Blast_Score=93, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6324292, Length=194, Percent_Identity=31.9587628865979, Blast_Score=100, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765
- InterPro:   IPR015892 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 23053; Mature: 23053

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: PS00705 PROK_CO2_ANHYDRASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLLKPLFDNNRRWAQRILQENPGFFETLAKQQNPEYLWIGCSDSRVPSNQIIDLLPGEV
CCCCHHHHCCCHHHHHHHHHCCCCHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHCCCCE
FVHRNIANMVIHTDLNCLSVLQYAVDVLQVKHIMVVGHYGCGGVRAAMGSARLGLIDNWL
EEECCHHHHHHHCCHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHCCCHHHHHHHHH
GHLRDIHRLHNDELTNLDDQARFDRLCELNVIEQVANVSESNIVQEAWARGQEVAIHGWI
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEEHHH
YGITNGLLTDLDVTVDRETFLGQ
HHHHCCHHCCCEEEECHHHHCCC
>Mature Secondary Structure
MKLLKPLFDNNRRWAQRILQENPGFFETLAKQQNPEYLWIGCSDSRVPSNQIIDLLPGEV
CCCCHHHHCCCHHHHHHHHHCCCCHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHCCCCE
FVHRNIANMVIHTDLNCLSVLQYAVDVLQVKHIMVVGHYGCGGVRAAMGSARLGLIDNWL
EEECCHHHHHHHCCHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHCCCHHHHHHHHH
GHLRDIHRLHNDELTNLDDQARFDRLCELNVIEQVANVSESNIVQEAWARGQEVAIHGWI
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEEHHH
YGITNGLLTDLDVTVDRETFLGQ
HHHHCCHHCCCEEEECHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8202364; 9278503; 10493123 [H]