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The map label for this gene is uvrC [H]

Identifier: 119774745

GI number: 119774745

Start: 1965437

End: 1967257

Strand: Direct

Name: uvrC [H]

Synonym: Sama_1608

Alternate gene names: 119774745

Gene position: 1965437-1967257 (Clockwise)

Preceding gene: 119774744

Following gene: 119774746

Centisome position: 45.64

GC content: 53.54

Gene sequence:

>1821_bases
GTGTTTGACCATAAAGCCTTTTTAAAAACGGTTTCCAGTGCCAGTGGCGTCTACCGCATGTATGACGCTGCGGCTGAGGT
TATCTATGTAGGAAAGGCAAAAGATCTGAAAAAGCGGCTGTCGTCCTATTTCCGGACGAATCTGCCCAATATCAAGACCC
AGGCTTTGGTTTCCAACATCGCCAACATCGATGTCACCCTTACCCACAGTGAGACCGAAGCATTAATCCTGGAAAATGAT
TACATCAAGCAGTACATGCCCAAATACAATGTGCTGCTCAGAGATGATAAATCCTACCCCTATATTTTGCTCAGTGGCCA
TAAACATCCCAGACTGGCCTACCACAGAGGCGCCCAGCGGGAGAAAGGGGAGTACTTTGGGCCGTACCCCAATGGCGGCG
CCGTGCGTGAAAGCCTCAATCTGATGCAAAAGCTGTTTCCCATCCGCCAGTGTGAAGATGCCTACTACCGCGCCCGCTCA
CGTCCCTGTCTGCAGTATCAAATTGGCCGCTGTTCGGCGCCCTGCGTCGGCAAAATTTCCGATGAGGACTACGACGAGCA
GGTAAGGCTGGCAACCCTGTTCCTCAGAGGAAAGGACCAACAGGTTATCGCCAGTTTGGTCGGCAAAATGGAAGCCGCAG
CACTGGCGATGGAATACGAGGCTGCAGCGCGCTATCGTGACCAAATTCAGGCGCTGCGCAAGGTTGCTGAGCAGCAAAAT
GTCTCAGGACAGCAGGGGGATATGGATGTTATCGGGGTGAATTACGCCTCAGGTATTGCCTGTTTTCATATCCTGTTTAT
CCGCGAAGGCAAGATTTTTGGCAGTCGCAGTTATTTCCCTGCGGTGCCTGATGCCACTGAGCTTGGCGAAGTGTTACGTG
CCTTTATGCTGCAATTCTATTTGGGAAATGAGGCGCACCGCAGCATTCCCAAGGAAGTCTTACTTGGCGAAGAGTTCGAA
GATCTCCATGAGCTTGAAGCCGCCATGCAGGATTCACTCGGTCACAGGCTTGAAATCAAAACCAAGGTGAGGGCAGATAG
GGCCGCGTTTTTACGCCTGGCCAATACCAATGCCGCCAATGCCGTTGTGACCAAGCTGGCACATAAAAGCACGGTTGAGC
AGCGTATGGAACTCCTGGAGGAAGTGCTGGGCCTTGGCGCACCCATACAACGCATGGAGTGTTTTGATATCAGTCACACC
ATGGGGGAAAGCACCGTTGCCTCCTGCGTGGTCTTTAACCGTGAAGGCCCCAATAAGGGGGAGTATCGTCGCTACAATAT
AAGCGGCATTACAGGGGGGGACGACTACGCGGCCATGGCTCAGGCGCTTTCCCGTCGGTTTGATAAGATTGAACGCACCG
GCAAGGTGCCCGATGTGCTTTTTATCGACGGCGGCCTGGGGCAGCTGCGAGCTGCCATGACGATAGTCAACGACAAGTTT
GCCGAACTTGACCGGCAACCGCTGCTTGTTGGGGTTGCAAAAGGGGAGAGCAGAAAGCCTGGGCTTGAAACCCTCATCTT
TGGTGGCAGTGAGGCCGAGTTTTCGTTGGAGTCCGATAATCCCGCGCTGCACCTCATCCAGCATATTCGCGATGAGTCCC
ACCGCTTTGCCATTACCGGCCACAGGGCGAAAAGGCAGCAAACCCGAAATACCTCGACTCTGGAGTCAATTCCCGGAATT
GGTCCCAAACGACGCAAGGCACTTCTGCAATATCTCGGCGGATTACAGCAAGTTAAAAATGCCAGTGTCGCCGAGCTTGC
GAAGGTGCCCGGGATCAGCGCAGAAATGGCGCAAACTATCCACGACGCATTGCGGGGGTGA

Upstream 100 bases:

>100_bases
ACCGCTATCGCCTATTTGCCAAATTAGGCATCAGCAGTGACGTTGAACTGACCCGTTTGGCTATTCGACATAAGATTATT
GATCCCGGCAAGTTTTAAGC

Downstream 100 bases:

>100_bases
CAAAAATCAGGCAAGATTGGCGCTGCTTTCGAACTCCCAGGGTTTCCCATGCCGTTTAATTTACCCATTGCCTTGACCTT
ATTCCGACTGTTTTTGTTAC

Product: excinuclease ABC subunit C

Products: NA

Alternate protein names: Protein uvrC; Excinuclease ABC subunit C [H]

Number of amino acids: Translated: 606; Mature: 606

Protein sequence:

>606_residues
MFDHKAFLKTVSSASGVYRMYDAAAEVIYVGKAKDLKKRLSSYFRTNLPNIKTQALVSNIANIDVTLTHSETEALILEND
YIKQYMPKYNVLLRDDKSYPYILLSGHKHPRLAYHRGAQREKGEYFGPYPNGGAVRESLNLMQKLFPIRQCEDAYYRARS
RPCLQYQIGRCSAPCVGKISDEDYDEQVRLATLFLRGKDQQVIASLVGKMEAAALAMEYEAAARYRDQIQALRKVAEQQN
VSGQQGDMDVIGVNYASGIACFHILFIREGKIFGSRSYFPAVPDATELGEVLRAFMLQFYLGNEAHRSIPKEVLLGEEFE
DLHELEAAMQDSLGHRLEIKTKVRADRAAFLRLANTNAANAVVTKLAHKSTVEQRMELLEEVLGLGAPIQRMECFDISHT
MGESTVASCVVFNREGPNKGEYRRYNISGITGGDDYAAMAQALSRRFDKIERTGKVPDVLFIDGGLGQLRAAMTIVNDKF
AELDRQPLLVGVAKGESRKPGLETLIFGGSEAEFSLESDNPALHLIQHIRDESHRFAITGHRAKRQQTRNTSTLESIPGI
GPKRRKALLQYLGGLQQVKNASVAELAKVPGISAEMAQTIHDALRG

Sequences:

>Translated_606_residues
MFDHKAFLKTVSSASGVYRMYDAAAEVIYVGKAKDLKKRLSSYFRTNLPNIKTQALVSNIANIDVTLTHSETEALILEND
YIKQYMPKYNVLLRDDKSYPYILLSGHKHPRLAYHRGAQREKGEYFGPYPNGGAVRESLNLMQKLFPIRQCEDAYYRARS
RPCLQYQIGRCSAPCVGKISDEDYDEQVRLATLFLRGKDQQVIASLVGKMEAAALAMEYEAAARYRDQIQALRKVAEQQN
VSGQQGDMDVIGVNYASGIACFHILFIREGKIFGSRSYFPAVPDATELGEVLRAFMLQFYLGNEAHRSIPKEVLLGEEFE
DLHELEAAMQDSLGHRLEIKTKVRADRAAFLRLANTNAANAVVTKLAHKSTVEQRMELLEEVLGLGAPIQRMECFDISHT
MGESTVASCVVFNREGPNKGEYRRYNISGITGGDDYAAMAQALSRRFDKIERTGKVPDVLFIDGGLGQLRAAMTIVNDKF
AELDRQPLLVGVAKGESRKPGLETLIFGGSEAEFSLESDNPALHLIQHIRDESHRFAITGHRAKRQQTRNTSTLESIPGI
GPKRRKALLQYLGGLQQVKNASVAELAKVPGISAEMAQTIHDALRG
>Mature_606_residues
MFDHKAFLKTVSSASGVYRMYDAAAEVIYVGKAKDLKKRLSSYFRTNLPNIKTQALVSNIANIDVTLTHSETEALILEND
YIKQYMPKYNVLLRDDKSYPYILLSGHKHPRLAYHRGAQREKGEYFGPYPNGGAVRESLNLMQKLFPIRQCEDAYYRARS
RPCLQYQIGRCSAPCVGKISDEDYDEQVRLATLFLRGKDQQVIASLVGKMEAAALAMEYEAAARYRDQIQALRKVAEQQN
VSGQQGDMDVIGVNYASGIACFHILFIREGKIFGSRSYFPAVPDATELGEVLRAFMLQFYLGNEAHRSIPKEVLLGEEFE
DLHELEAAMQDSLGHRLEIKTKVRADRAAFLRLANTNAANAVVTKLAHKSTVEQRMELLEEVLGLGAPIQRMECFDISHT
MGESTVASCVVFNREGPNKGEYRRYNISGITGGDDYAAMAQALSRRFDKIERTGKVPDVLFIDGGLGQLRAAMTIVNDKF
AELDRQPLLVGVAKGESRKPGLETLIFGGSEAEFSLESDNPALHLIQHIRDESHRFAITGHRAKRQQTRNTSTLESIPGI
GPKRRKALLQYLGGLQQVKNASVAELAKVPGISAEMAQTIHDALRG

Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision [H]

COG id: COG0322

COG function: function code L; Nuclease subunit of the excinuclease complex

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Escherichia coli, GI87081999, Length=610, Percent_Identity=60.655737704918, Blast_Score=752, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003583
- InterPro:   IPR010994
- InterPro:   IPR001943
- InterPro:   IPR009055
- InterPro:   IPR004791
- InterPro:   IPR001162
- InterPro:   IPR000305 [H]

Pfam domain/function: PF01541 GIY-YIG; PF02151 UVR; PF08459 UvrC_HhH_N [H]

EC number: NA

Molecular weight: Translated: 67602; Mature: 67602

Theoretical pI: Translated: 8.56; Mature: 8.56

Prosite motif: PS50151 UVR ; PS50164 UVRC_1 ; PS50165 UVRC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDHKAFLKTVSSASGVYRMYDAAAEVIYVGKAKDLKKRLSSYFRTNLPNIKTQALVSNI
CCCHHHHHHHHHHCCCHHHHHHHHHHEEEECCHHHHHHHHHHHHHCCCCCHHHHHHHHHH
ANIDVTLTHSETEALILENDYIKQYMPKYNVLLRDDKSYPYILLSGHKHPRLAYHRGAQR
CCEEEEEEECCCCEEEEECHHHHHHCCCCCEEEECCCCCCEEEEECCCCCCHHHHCCCCC
EKGEYFGPYPNGGAVRESLNLMQKLFPIRQCEDAYYRARSRPCLQYQIGRCSAPCVGKIS
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCC
DEDYDEQVRLATLFLRGKDQQVIASLVGKMEAAALAMEYEAAARYRDQIQALRKVAEQQN
CCCHHHHHEEHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
VSGQQGDMDVIGVNYASGIACFHILFIREGKIFGSRSYFPAVPDATELGEVLRAFMLQFY
CCCCCCCEEEEECCHHHHHHHHHHHHEECCCEECCCCCCCCCCCHHHHHHHHHHHHHHHH
LGNEAHRSIPKEVLLGEEFEDLHELEAAMQDSLGHRLEIKTKVRADRAAFLRLANTNAAN
HCCHHHHCCCHHHHCCCHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHEECCCCHHH
AVVTKLAHKSTVEQRMELLEEVLGLGAPIQRMECFDISHTMGESTVASCVVFNREGPNKG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHEEEEECCCCCCC
EYRRYNISGITGGDDYAAMAQALSRRFDKIERTGKVPDVLFIDGGLGQLRAAMTIVNDKF
CEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHH
AELDRQPLLVGVAKGESRKPGLETLIFGGSEAEFSLESDNPALHLIQHIRDESHRFAITG
HHCCCCCEEEEEECCCCCCCCCCEEEECCCCCEEEECCCCHHHHHHHHHHCCCCEEEEEC
HRAKRQQTRNTSTLESIPGIGPKRRKALLQYLGGLQQVKNASVAELAKVPGISAEMAQTI
CHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHH
HDALRG
HHHHCC
>Mature Secondary Structure
MFDHKAFLKTVSSASGVYRMYDAAAEVIYVGKAKDLKKRLSSYFRTNLPNIKTQALVSNI
CCCHHHHHHHHHHCCCHHHHHHHHHHEEEECCHHHHHHHHHHHHHCCCCCHHHHHHHHHH
ANIDVTLTHSETEALILENDYIKQYMPKYNVLLRDDKSYPYILLSGHKHPRLAYHRGAQR
CCEEEEEEECCCCEEEEECHHHHHHCCCCCEEEECCCCCCEEEEECCCCCCHHHHCCCCC
EKGEYFGPYPNGGAVRESLNLMQKLFPIRQCEDAYYRARSRPCLQYQIGRCSAPCVGKIS
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCC
DEDYDEQVRLATLFLRGKDQQVIASLVGKMEAAALAMEYEAAARYRDQIQALRKVAEQQN
CCCHHHHHEEHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
VSGQQGDMDVIGVNYASGIACFHILFIREGKIFGSRSYFPAVPDATELGEVLRAFMLQFY
CCCCCCCEEEEECCHHHHHHHHHHHHEECCCEECCCCCCCCCCCHHHHHHHHHHHHHHHH
LGNEAHRSIPKEVLLGEEFEDLHELEAAMQDSLGHRLEIKTKVRADRAAFLRLANTNAAN
HCCHHHHCCCHHHHCCCHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHEECCCCHHH
AVVTKLAHKSTVEQRMELLEEVLGLGAPIQRMECFDISHTMGESTVASCVVFNREGPNKG
HHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHEEEEECCCCCCC
EYRRYNISGITGGDDYAAMAQALSRRFDKIERTGKVPDVLFIDGGLGQLRAAMTIVNDKF
CEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHH
AELDRQPLLVGVAKGESRKPGLETLIFGGSEAEFSLESDNPALHLIQHIRDESHRFAITG
HHCCCCCEEEEEECCCCCCCCCCEEEECCCCCEEEECCCCHHHHHHHHHHCCCCEEEEEC
HRAKRQQTRNTSTLESIPGIGPKRRKALLQYLGGLQQVKNASVAELAKVPGISAEMAQTI
CHHHHHHHCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHH
HDALRG
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA